10 results on '"Brundage, Michael D."'
Search Results
2. Engaging stakeholders to improve presentation of patient-reported outcomes data in clinical practice
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Smith, Katherine C., Brundage, Michael D., Tolbert, Elliott, Little, Emily A., Bantug, Elissa T., Snyder, Claire F., and PRO Data Presentation Stakeholder Advisory Board
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- 2016
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3. Application of Value Frameworks to the Design of Clinical Trials: The Canadian Cancer Trials Group Experience.
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Paggio, Joseph C Del, Fundytus, Adam M, Hopman, Wilma M, Pater, Joseph L, Chen, Bingshu E, Brundage, Michael D, Hay, Annette E, Booth, Christopher M, and Del Paggio, Joseph C
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EXPERIMENTAL design ,OVERALL survival ,PROGRESSION-free survival ,RANDOMIZED controlled trials ,STATISTICAL power analysis ,TUMORS ,ONCOLOGY - Abstract
Background: Use of value framework thresholds in the design of clinical trials may increase the proportion of randomized controlled trials that identify clinically meaningful advances for patients. Existing frameworks have not been applied to the research output of a cooperative cancer trials group. We apply value frameworks to the randomized controlled trial output of the Canadian Cancer Trials Group (CCTG).Methods: Statistical design, study characteristics, and results of all published phase III trials of CCTG were abstracted. We applied the European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) and American Society of Clinical Oncology Net Health Benefit to study results and the statistical power calculations to identify the proportion of all trials that were designed to detect a substantial clinical benefit.Results: During 1979 to 2017, CCTG published 113 phase III trials; 52.2% (59 of 113) of these trials were positive. One-half (50.4%, 57 of 113) of the trials were conducted in the palliative setting. In 37.2% (42 of 113) of trials, the primary endpoint was overall survival; disease-free survival or progression-free survival was used in 38.9% (44 of 113) of trials. The ESMO-MCBS could be applied to the power calculation for 69 trials; 73.9% (51 of 69) of these trials were designed to detect an effect size that could meet ESMO-MCBS thresholds for substantial benefit. Among the 51 positive trials for which the ESMO-MCBS could be applied, 41.1% (21 of 51) met thresholds for substantial benefit.Conclusions: Most CCTG phase III trials were designed to detect clinically meaningful differences in outcome, although less than one-half of positive trials met the threshold for substantial benefit. Application of value frameworks to the design of clinical trials is practical and may improve research efficiency and treatment options for patients. [ABSTRACT FROM AUTHOR]- Published
- 2021
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4. Medical Oncology in India: Workload, Infrastructure, and Delivery of Care.
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Sengar, Manju, Fundytus, Adam, Hopman, Wilma M., Malhotra, Hemant, Gupta, Sudeep, Pramesh, C. S., Hammad, Nazik, Sullivan, Richard, Vanderpuye, Verna, Seruga, Bostjan, Lopes, Gilberto, Brundage, Michael D., and Booth, Christopher M.
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ONCOLOGISTS ,HUMAN resource planning ,ONCOLOGY ,HEALTH planning ,TUMORS in children ,EMPLOYEE vacations - Abstract
Background: The growing burden of cancer within India has implications across the health system including operational delivery of cancer care and planning for human health resources. Here, we report the Indian results of a global survey of medical oncology (MO) workload in comparison to medical oncologists (MOs) in other low-middle-income countries (LMICs). Methods: An online survey was distributed through a snowball method through national oncology societies to chemotherapy-prescribing physicians in 22 LMICs. The survey was distributed to Indian MOs by the Indian Society of Medical and Pediatric Oncology and the National Cancer Grid of India. The workload was measured as the annual number of new cancer patient consults seen per oncologist. Results: One hundred and forty-seven oncologists from LMICs completed the survey; 82 from India and 65 from other LMICs. About 59% (48/82) of Indian MOs reported working exclusively in the private health system compared to 23% (15/65) of MOs in other LMICs (P < 0.001). The median number of annual consults per MO was 475 in India compared with 350 in other LMICs. The proportion of MOs seeing >1000 new consults/year was 24% (20/82) in India and 20% (13/65) in other LMICs (P = 0.530). The median number of patients seen in a full-day clinic was 35 in India and 25 in other LMCs (P = 0.003); 26% of Indian MO reported seeing >50 patients per day. Compared to other LMICs, Indian MOs worked more days/week (median 6 vs. 5, P < 0.001) and hours/week (median 51-60 vs. 41-50, P = 0.004) and had less annual leave for vacation (3 weeks vs. 4, P = 0.017). Conclusion: Indian MOs have higher clinical volumes and workload than MOs in other LMICs and substantially higher workload than MOs in high-income countries. Indian health policymakers should consider alternative models of care and increasing MO workforce supply to address the growing burden of cancer. [ABSTRACT FROM AUTHOR]
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- 2019
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5. Delivery of Global Cancer Care: An International Study of Medical Oncology Workload.
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Fundytus, Adam, Sullivan, Richard, Vanderpuye, Verna, Seruga, Bostjan, Lopes, Gilberto, Hammad, Nazik, Sengar, Manju, Hopman, Wilma M., Brundage, Michael D., and Booth, Christopher M.
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ONCOLOGY ,CANCER chemotherapy ,DRUG prescribing ,CANCER patients ,CANCER treatment - Abstract
Background To our knowledge, there is no literature that has described medical oncology (MO) workload in the global context. Here, we report results of an international study of global MO workload. Methods An online survey was distributed through a snowball method via national oncology societies to chemotherapy-prescribing physicians in 65 countries. Countries were classified into low- or low-middle–income countries (LMICs), upper-middle–income countries (UMICs), and high-income countries (HICs) on the basis of World Bank criteria. Workload was measured as the annual number of new consultations provided to patients with cancer per oncologist. Results A total of 1,115 physicians completed the survey: 13% (147 of 1,115) from LMICs, 17% (186 of 1,115) from UMICs, and 70% (782 of 1,115) from HICs. Eighty percent (897 of 1,115) of respondents were medical oncologists, 10% (109 of 1,115) were clinical oncologists, and 10% (109 of 1,115) were other. The median number of annual consults per oncologist was 175 (interquartile range, 75 to 275); 13% (140 of 1,103) saw ≥ 500 new patients in a year. Annual case volume in LMICs (median consults, 425; 40% of respondents seeing > 500 consults) was substantially higher than in UMICs (median consults, 175; 14% > 500) and HICs (median consults, 175; 7% > 500; P < .001). Among LMICs, UMICs, and HICs, median working days per week were 6, 5, and 5, respectively (P < .001). The highest annual case volumes per oncologist were in Pakistan (median consults, 950; 73% > 500 consults), India (median consults, 475; 43% > 500), and Turkey (median consults, 475; 27% > 500). Conclusion There is substantial global variation in medical oncology case volumes and clinical workload; this is most striking among LMICs, where huge deficits exist. Additional work is needed, particularly detailed country-level mapping, to quantify activity-based global MO practice and workload to inform training needs and the design of new pathways and models of care. [ABSTRACT FROM AUTHOR]
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- 2018
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6. How do interventions designed to improve provider-patient communication work? Illustrative applications of a framework for communication.
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Brundage, Michael D., Feldman-Stewart, Deb, and Tishelman, Carol
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PHYSICIAN-patient relations , *MEDICAL communication , *CANCER patient medical care , *COMMUNICATIONS research , *ONCOLOGY - Abstract
In this broad overview for the Conference: “State of the Science in Cancer Care”, we review a conceptual framework of physician-patient communication and use the framework to inform the application of theory regarding communication and patient preferences in clinical practice. Using a selection of research, we illustrate how problematic issues in communication can be represented by the framework. We further illustrate how interventions designed to improve communication or to elicit patients’ preferences in a medical encounter may have their desired effect, or may be optimally evaluated. [ABSTRACT FROM AUTHOR]
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- 2010
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7. Patient–professional communication research in cancer: an integrative review of research methods in the context of a conceptual framework.
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Carlson, Linda E., Feldman-Stewart, Deb, Tishelman, Carol, and Brundage, Michael D.
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CANCER patients ,PHYSICIAN-patient relations ,PROFESSIONAL-patient communication ,PATIENT-professional relations ,INTERPERSONAL relations ,ONCOLOGY ,RESEARCH ,INTERPERSONAL communication - Abstract
This paper uses the conceptual framework of Feldman-Stewart et al. to organize and review the types of research methodologies used to investigate various aspects of patient-health care professional communication in the context of cancer. Research methods employed are classified as either non-experimental or experimental. Non-experimental designs include naturalistic observational studies (e.g. participant observation, audio- or videotaping of interactions) and retrospective introspective descriptions (e.g. self-report questionnaires, qualitative interview methods). Experimental designs often involve interventions aimed at improving communication, such as physician or patient training, and the use of technology to enhance communication (e.g. audiotapes, computers). Using the conceptualization of the communication framework description, we argue that the outcome measures used in these studies address either primary goals, enabling goals, or secondary communication outcomes. Outcomes that are related to primary goals of the communication exchange include assessing the level of understanding of information conveyed, aspects of decision making, planning around treatments, or general provision of care. Outcomes related to enabling goals focus on elements that affect the ability to achieve primary goals. Outcomes secondary to the communication do not relate directly to what the communication is attempting to achieve. We conclude by identifying priority areas for further research, such as identifying the goals of both participants, understanding how particular aspects of the communication process affect their ability to achieve their goals, and examining the external environment in which communication takes place. Copyright © 2005 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
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- 2005
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8. What do we know about facilitating patient communication in the cancer care setting?
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Parker, Patricia A., Davison, B. Joyce, Tishelman, Carol., and Brundage, Michael D.
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CANCER patients ,PHYSICIAN-patient relations ,PROFESSIONAL-patient communication ,PATIENT-professional relations ,INTERPERSONAL communication ,INTERPERSONAL relations ,ONCOLOGY - Abstract
Throughout the cancer diagnosis and treatment period, patients interact with multiple healthcare providers. In order to facilitate these communications, researchers have developed interventions primarily for providers, and, more recently, for patients. The aim of this paper is to conduct a critical examination of a sample of the empirical literature regarding current knowledge about the types of interventions that have been designed to facilitate cancer patients' communication with their healthcare providers. Overall, the empirical literature suggests that some types of patient-based interventions (e.g. prompt sheets, audiotapes, coaching sessions) may be beneficial in specific areas (e.g. increasing the number of questions asked, increased patient satisfaction). However, there are few consistent findings and the outcome measures that have been examined have varied substantially across studies. More controlled studies using carefully chosen outcome variables are needed. Increasing patients' communication skills so that their goals are met has the potential to positively affect the communication process. Copyright © 2005 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]
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- 2005
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9. Cancer care workforce in Africa: perspectives from a global survey.
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Vanderpuye, Verna, Hammad, Nazik, Martei, Yehoda, Hopman, Wilma M., Fundytus, Adam, Sullivan, Richard, Seruga, Bostjan, Lopes, Gilberto, Sengar, Manju, Brundage, Michael D., and Booth, Christopher M.
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ATTITUDE (Psychology) ,CANCER patient medical care ,COMPARATIVE studies ,JOB satisfaction ,MEDICAL appointments ,MEDICAL care ,MEDICAL quality control ,MEDICAL personnel ,ONCOLOGY ,ONLINE information services ,STATISTICAL sampling ,SCALE analysis (Psychology) ,SURVEYS ,WORLD health ,EMPLOYEES' workload ,PRIVATE sector ,DESCRIPTIVE statistics - Abstract
Background: While the burden of cancer in Africa is rapidly rising, there is a lack of investment in healthcare professionals to deliver care. Here we report the results of a survey of systemic therapy workload of oncologists in Africa in comparison to oncologists in other countries. Methods: An online survey was distributed through a snowball method via national oncology societies to chemotherapy-prescribing physicians in 65 countries. The survey was distributed within Africa through a network of physicians associated with the African Organisation for Research and Training in Cancer (AORTIC). Workload was measured as the annual number of new cancer patient consults seen per oncologist. Job satisfaction was ranked on a 10-point Likert scale; scores of 9–10 were considered to represent high job satisfaction. Results: Thirty-six oncologists from 18 countries in Africa and 1079 oncologists from 47 other countries completed the survey. Compared to oncologists from other countries, African oncologists were older (median age 51 vs 44 years, p = 0.007), more likely to prescribe chemotherapy and radiation [61% (22/36) vs 10% (108/1079), p < 0.001], less likely to have completed training in their home country [50% (18/36) vs 91% (979/1079), p < 0.001], and more likely to work in the private sector [47% (17/36) vs 34% (364/1079), p = 0.037]. The median number of annual consults per oncologist was 325 in Africa compared to175 in other countries. The proportion of oncologists seeing > 500 consults/year was 31% (11/36) in Africa compared to 12% (129/1079) in other countries (p = 0.001). African oncologists were more likely than global colleagues to see all cancer sites [72% (26/26) vs 24% (261/1079), p < 0.001]. Oncologists in Africa were less likely than other oncologists to have high job satisfaction [17% (6/36) vs 30% (314/1079), p = 0.013]. Conclusion: African oncologists within the AORTIC network have a substantially higher clinical workload and lower job satisfaction than oncologists elsewhere in the world. There is an urgent need for governments and health systems to improve the oncologist-to-patient ratio and develop new models of capacity building, retention and skills enhancement to strengthen the wide variety of cancer care systems across continental Africa. [ABSTRACT FROM AUTHOR]
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- 2019
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10. Directly Improving the Quality of Radiation Treatment Through Peer Review: A Cross-sectional Analysis of Cancer Centers Across a Provincial Cancer Program.
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Rouette, Julie, Gutierrez, Eric, O'Donnell, Jennifer, Reddeman, Lindsay, Hart, Margaret, Foxcroft, Sophie, Mitera, Gunita, Warde, Padraig, Brundage, Michael D., O'Donnell, Jennifer, Cancer Care Ontario Radiation Oncology Program Leads and, Pan-Canadian Peer Review Steering Committee, and Cancer Care Ontario Radiation Oncology Program Leads
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CANCER radiotherapy , *RADIOTHERAPY treatment planning , *MEDICAL quality control , *CROSS-sectional method , *HEALTH outcome assessment , *HOSPITAL statistics , *HUMAN body , *CANCER treatment , *COMPARATIVE studies , *HOSPITALS , *RESEARCH methodology , *MEDICAL cooperation , *COMPUTERS in medicine , *ONCOLOGY , *PROFESSIONAL peer review , *QUALITY assurance , *RADIATION doses , *RADIOTHERAPY , *RESEARCH , *TIME , *TUMORS , *EVALUATION research , *SPECIALTY hospitals , *TREATMENT effectiveness , *STANDARDS - Abstract
Purpose: To describe the outcomes of peer review across all 14 cancer centers in Ontario.Methods and Materials: We identified all peer-reviewed, curative treatment plans delivered in Ontario within a 3-month study period from 2013 to 2014 using a provincial cancer treatment database and collected additional data on the peer-review outcomes.Results: Considerable variation was found in the proportion of peer-reviewed plans across the centers (average 70.2%, range 40.8%-99.2%). During the study period, 5561 curative plans underwent peer review. Of those, 184 plans (3.3%) had changes recommended. Of the 184 plans, the changes were major (defined as requiring repeat planning or having a major effect on planning or clinical outcomes, or both) in 40.2% and minor in 47.8%. For the remaining 12.0%, data were missing. The proportions of recommended changes varied among disease sites (0.0%-7.0%). The disease sites with the most recommended changes to treatment plans after peer review and with the greatest potential for benefit were the esophagus (7.0%), uterus (6.7%), upper limb (6.3%), cervix and lower limb (both 6.0%), head and neck and bilateral lung (both 5.9%), right supraclavicular lymph nodes (5.7%), rectum (5.3%), and spine (5.0%). Although the heart is an organ at risk in left-sided breast treatment plans, the proportions of recommended changes did not significantly differ between the left breast treatment plans (3.0%, 95% confidence interval 2.0%-4.5%) and right breast treatment plans (2.4%, 95% confidence interval 1.5%-3.8%). The recommended changes were more frequently made when peer review occurred before radiation therapy (3.8%) than during treatment (1.4%-2.8%; P=.0048). The proportion of plans with recommended changes was not significantly associated with patient volume (P=.23), peer-review performance (P=.36), or center academic status (P=.75).Conclusions: Peer review of treatment plans directly affects the quality of care by identifying important clinical and planning changes. Provincial strategies are underway to optimize its conduct in radiation oncology. [ABSTRACT FROM AUTHOR]- Published
- 2017
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