Search

Background: The authors present the results of medical examinations of workers employed in an aluminum electrolysis plant with occupational exposure to aluminum dust, polycyclic aromatic hydrocarbons, and magnetic field., Methods and Materials: The study covered a selected group of 39 male workers (mean age, 44,9; SD = 7.5 years; range 29-55 years) involved in the aluminum production. Their employment duration ranged between 5 and 32 years (mean, 17.8; SD = 6.7 years). Urine aluminum concentrations in workers ranged from 8.9 to 70.2 microg/g creatinine (mean, 31.72; SD = 18.3 microg/g creatinine). Urine 1-hydroxypyrene concentrations recorded in workers ranged from 0.67 to 10.09 microg/g creatinine (mean, 3.42; SD = 2.1 microg/g creatinine). The control group consisted of 39 men matched by gender, age and work shifts., Results: Clinical symptoms, such as headache (46.2%), increased emotional irritability (66.7%), concentration difficulty (25.6%), insomnia (30.8%), hypersomnia (15.4%), and mood lability (10.3%) predominated among functional disorders of the nervous system in workers chronically exposed to chemical and physical factors. The objective neurological examinations did not reveal organic lesions in the central or peripheral nervous system. In EEG recordings, classified as abnormal, paroxysmal changes were most common (20.5%)., Conclusions: The authors emphasized great difficulty in evaluating the combined effects of toxic and physical factors exerted on the nervous system.

Background: Studies conducted to assess aluminum (Al)-induced toxicity to humans and environment. It has been implicated that Al is involved in the etiology of Alzheimer's disease and other neurodegenerative disorders, though this is controversial. The aim of the present study was to assess Al effects on the nervous system functions in workers chronically exposed to this metal., Methods and Materials: The study covered a selected group of 67 male workers (mean age, 38.7 +/- 10.3 years; range 23-55 years) involved in aluminum production. Their employment duration ranged between 2 and 34 years (mean, 14.6 +/- 8.9 years). Aluminum oxide (Al2O3) concentrations varied from 0.2 to 1.95 mg/m3 (arithmetic mean, 0.40 mg/m3, geometric mean, 0.35 mg/m3, SD = 0.29). Urine aluminum concentrations found in smelters ranged from 8.5 to 93.0microg/l (mean, 42.9 +/- 20.5 microg/l). The control group consisted of 57 men non-occupationally exposed to Al matched by gender, age and work shifts., Results: Clinically, headache (41,8%), increased emotional irritability (56,7%), concentration difficulty (22,4%), insomnia (22,4%) and mood lability (14,9%) predominated among functional disorders of the nervous system in workers chronically exposed to Al. The objective neurological examinations did not reveal organic lesions in the central or peripheral nervous system. In EEG classified as abnormal, generalized and paroxysmal changes were most common. Examinations of visual evoked potentials (VEP) revealed abnormalities, primarily in the latency of the response evoked., Conclusions: The results of this study suggest that exposure to Al2O3 at concentrations within MAC values induces subclinical effect in the nervous system.

Exposure of MMA/Plasma/Cu welders to fumes and soluble and insoluble Cu was assessed. Mean weighted concentrations of dusts/fumes and copper compounds at the welders' breathing zone were: 3.1 mg/m3 (0.7-7.6 mg/m3) for fumes; 0.08 mg/m3 (0.02-0.17 mg/m3) for soluble Cu; and 0.39 mg/m3 (0.08-0.76 mg/m3) for insoluble Cu. Correlation was found between the concentration of Cu compounds and fume/dust concentrations (r = 0.55 MMA/Plasma/Cu; r = 0.93 MMA/Cu). The mean percentage of copper in fumes/dusts was 17 (9.5-28.5%). Our results show that copper welding may pose a hazard to the welders' health. The index of combined exposure to determined agents was 1.2 (0.3-2.6), including soluble Cu (0.8) and insoluble Cu (0.4). The proportion of respirable fraction of fumes and their components varied between 40-80%. The background concentrations of the components (about 6 times lower than those in the welders' breathing zone) did not exceed the MAC value.

The measurements of air pollutions in the rolling mill of non-ferrous metals aimed at the evaluation of occupational exposure to nickel and other metals (Cu, Zn, Mn, Mg) used during the production of nickel alloys. It was found that nickel fumes and dusts concentration can be the only hazardous factor for the workers' health. The majority (ca 85%) of the crew of 28 workers is exposed to the nickel concentration in air exceeding 0.05 mg/m3. Smelters (8 persons) at the stand of 97-99% nickel smelting are at the highest risk of the loss of health; average exposure of this group during 8 hours' shift may surpass 2 mg Ni/m3. Mean concentration in air of the fumes and dusts of copper, zinc, manganese and magnesium do not make a hygienic problem.