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1. Contents Vol. 53, 2008

Author

Sylvia Cruchet, Helmut F. Erbersdobler, F. Shojaee-Moradie, Mirosław Jarosz, J.V. Bargieri, Aisha Al-Kubaisi, Chong-Eon Lee, Jae-Youn Kim, A.A.J. Quadros, G. Oriani, Anne Noatsch, Masoumeh Sadeghi, Elzbieta Sochacka-Tatara, Alison E. Harvey, Choong-Nam Kim, Young-Hoon Yang, S. Verwied-Jorky, Savita Mehendale, V. Dolz, Tingna Lu, Gerardo Guiter, Cristina Campoy, Zengnan Mo, Marcellina Mian, Juan O Talavera, P. Buono, Elisabeth Haschke-Becher, Gerardo Huitrón-Bravo, A. Daniele, J.C. Galofré, G. Salvatori, Veronika Somoza, Gabriele I. Stangl, Marise Lazaretti-Castro, Yinglong Xu, Rebekah R. Smith, Luis Ortiz-Hernández, Corinna Brandsch, Sarah Egert, Agnieszka Pac, Gaby Andersen, G. Calcagno, T. Martin, Grażyna Sygitowicz, J.C. Díaz-Montiel, Esperanza Martínez-Abundis, M. Siavash, Yunfei Cao, L. Cuellar, Basma Basha, Klaus Eder, Umberto Maugeri, M.C. Terroba, Samer A. Al Baz, Vaishali Taralekar, Amit Abraham, A.C. Silva, Amer Alsaied, Kamini Dangat, J.F. Pariz López-Madrueño, Tamás Decsi, C. Abreu, Alejandra Jiménez-Aguilar, P. Pujante, Martin Gotteland, C. Nardelli, Manuel González-Ortiz, Sadhana Joshi, Tamara Lewis, Grażyna Nowicka, Hosam M. Habib, Daniel Diaz, M. Amini, O. Izaola, Kyu-Il Kim, Wissam H. Ibrahim, Julia Spielmann, Hemlata R. Yadav, Ferdinand Haschke, F. Guillen-Grima, Abdulbari Bener, Elizabeth Halley-Castillo, Roberto Medina-Santillán, Maricarmen Teresa Genis Gómez, Oscar Brunser, L. Sacchetti, Aleksander Galas, A.J.B. Oliveira, Nomeli P. Nunez, J. Salvador, Danuta Zapolska-Downar, F. Salarifar, Jina Hong, C. Finelli, Abdelmonem S. Hassan, Amjad H. Jarrar, G. Frühbeck, G. Labruna, Manfred Fobker, Roberto Dias Batista Pereira, Anitha Kilari, Berthold Koletzko, Feng Gao, R. Cammarata, Wieslaw Jedrychowski, Nancy Paulina López Olmedo, Dulce Paola Melchor López, Mariam Al-Ali, M. Trak-Fellermeier, R. Bracale, S. Santos, Claude Bachmann, D. Pineda-Pérez, Jesús Valdés Flores, F. Contaldo, Omar Jacques-Camarena, Ihab Tewfik, Ursel Wahrburg, D. Pacheco, Edgar Denova-Gutiérrez, C. Franke, Jorge Salmerón, D.A. de Luis, and F. Pasanisi

Subjects
Gerontology, Nutrition and Dietetics, Anthropology, Philosophy, Medicine (miscellaneous)
Published
2008

2. Differential susceptibility to obesity between male, female and ovariectomized female mice

Author

Alison E. Harvey, Nomeli P. Nunez, Renee E. Stubbins, Jina Hong, and Rebekah R. Smith

Subjects
Male, medicine.medical_specialty, Calorie, Ovariectomy, Short Report, Medicine (miscellaneous), 030209 endocrinology & metabolism, lcsh:TX341-641, Clinical nutrition, Weight Gain, Mice, 03 medical and health sciences, Absorptiometry, Photon, Sex Factors, 0302 clinical medicine, Internal medicine, Animals, Medicine, Obesity, lcsh:RC620-627, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Nutrition and Dietetics, business.industry, Incidence (epidemiology), Confounding, medicine.disease, Dietary Fats, 3. Good health, Mice, Inbred C57BL, Menopause, lcsh:Nutritional diseases. Deficiency diseases, Endocrinology, Female, Disease Susceptibility, medicine.symptom, Energy Intake, business, Weight gain, lcsh:Nutrition. Foods and food supply, Gonadal Hormones, Hormone
Abstract

Background The prevalence of obesity has increased dramatically. A direct comparison in the predisposition to obesity between males, premenopausal females, and postmenopausal females with various caloric intakes has not been made. To determine the effects of sex and ovarian hormones on the susceptibility to obesity, we conducted laboratory studies with mice. To eliminate confounders that can alter body weight gain, such as age and food consumption; we used mice with the same age and controlled the amount of calories they consumed. Methods We determined sex-specific susceptibility to obesity between male, non-ovariectomized female, and ovariectomized female mice. To compare susceptibility to gaining body weight between males and females, animals from each sex were exposed to either a 30% calorie-restricted, low-fat (5% fat), or high-fat (35% fat) diet regimen. To establish the role of ovarian hormones in weight gain, the ovaries were surgically removed from additional female mice, and then were exposed to the diets described above. Percent body fat and percent lean mass in the mice were determined by dual energy x-ray absorptiometry (DEXA). Results In all three diet categories, male mice had a greater propensity of gaining body weight than female mice. However, ovariectomy eliminated the protection of female mice to gaining weight; in fact, ovariectomized female mice mimicked male mice in their susceptibility to weight gain. In summary, results show that male mice are more likely to become obese than female mice and that the protection against obesity in female mice is eliminated by ovariectomy. Conclusion Understanding metabolic differences between males and females may allow the discovery of better preventive and treatment strategies for diseases associated with body weight such as cancer and cardiovascular disease.

Published
2009

3. Alcohol consumption promotes insulin sensitivity without affecting body fat levels

Author

Nomeli P. Nunez, Rebekah R. Smith, Jina Hong, and Alison E. Harvey

Subjects
Blood Glucose, Male, medicine.medical_specialty, Alcohol Drinking, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Medicine (miscellaneous), Adipose tissue, Mice, Insulin resistance, Internal medicine, medicine, Animals, Glucose tolerance test, Nutrition and Dietetics, medicine.diagnostic_test, business.industry, Insulin, Insulin tolerance test, Body Weight, Glucose Tolerance Test, medicine.disease, Obesity, Diet, Mice, Inbred C57BL, Endocrinology, Adipose Tissue, Lean body mass, Blood sugar regulation, Insulin Resistance, business
Abstract

Alcohol consumption promotes insulin sensitivity. In obesity, a decrease in body fat levels decreases the risk of developing insulin resistance; therefore, it is possible that alcohol improves insulin sensitivity by negatively affecting body fat. The aim of this study was to determine whether alcohol consumption promotes insulin sensitivity by reducing body fat levels in C57BL/6 male mice. We examined the effects of alcohol consumption on insulin sensitivity in male mice with three different body weight (BW) phenotypes. The BWs were induced by feeding the mice a 30% calorie-restricted (CR) regimen, a low-fat (LF) diet and a high-fat (HF) diet. The mice had free access to water or 20% ethanol in the drinking water. To determine the effects of the three different BW phenotypes and of alcohol on glucose regulation and insulin sensitivity, we performed the insulin tolerance test (ITT) and glucose tolerance test (GTT) on the mice. The effects of the diets and alcohol on body composition, percent body fat (% BF), percent lean mass and bone mineral density (BMD) were determined by dual-energy X-ray absorptiometry (DEXA). Data show that mice with the highest body fat levels (HF) were insulin resistant and glucose intolerant. In contrast, mice with the lowest body fat levels (CR) were the most insulin sensitive and cleared the injected endogenous glucose the fastest. Results show that alcohol did not affect GTT in any of the BW phenotypes. However, alcohol consumption promoted insulin sensitivity in mice consuming both the LF and HF diets. Alcohol consumption increased insulin sensitivity without affecting body fat levels, as body fat levels were similar in mice consuming the LF or HF diets and drinking either water or alcohol. Alcohol consumption promotes insulin sensitivity without affecting body fat levels in mice consuming LF and HF diets.

Published
2009

4. Ethanol consumption does not promote weight gain in female mice

Author

Rebekah R. Smith, Alison E. Harvey, Jina Hong, Nomeli P. Nunez, Tamara Lewis, and Daniel Diaz

Subjects
Diet, Reducing, Ovariectomy, Medicine (miscellaneous), Weight Gain, chemistry.chemical_compound, Mice, Random Allocation, High fat, Medicine, Animals, Food science, Obesity, Random allocation, Consumption (economics), Nutrition and Dietetics, Ethanol, business.industry, Extramural, Adipose tissue metabolism, Obese adult, Dietary Fats, Specific Pathogen-Free Organisms, chemistry, Adipose Tissue, Body Composition, Female, medicine.symptom, business, Energy Intake, Weight gain
Abstract

Background: The prevalence of obese adult women has increased dramatically in the United States. Individuals consuming alcoholic beverages may obtain as much as 6–10% of their calories from ethanol; consequently, ethanol may contribute to a positive energy balance and weight gain in women consuming ethanol. The objective of these studies is to determine if ethanol consumption affects weight gain or body fat levels in female mice. Methods: In order to determine the effects of ethanol consumption on weight gain, female mice were given either water or 20% w/v ethanol in the drinking water; mice were then placed on 1 of 3 diets for 20 weeks: (1) 30% calorie-restricted diet, (2) low-fat diet or (3) high-fat diet. Mice were scanned using a GE Lunar Piximus Densitometer to determine body fat, lean body mass and bone mineral density. Results: Mice consuming the high-fat diet had the highest body weight. Moreover, ovariectomy exacerbated the effects of the high-fat diet. That is, ovariectomized female mice consuming the high-fat diet gained a higher amount of body weight and adipose tissue than nonovariectomized mice consuming the high-fat diet. Ethanol-consuming mice did not have a higher susceptibility to gaining body weight or body fat, even though they tended to have higher caloric intake than water-consuming mice. Conclusions: In female mice that consumed a high-fat diet, chronic ethanol consumption did not increase susceptibility to gaining weight or becoming obese.

Published
2008

5. Subject Index Vol. 53, 2008

Author

Marise Lazaretti-Castro, Yinglong Xu, Elisabeth Haschke-Becher, Rebekah R. Smith, A. Daniele, Cristina Campoy, G. Calcagno, Tingna Lu, Gabriele I. Stangl, F. Pasanisi, Claude Bachmann, D. Pineda-Pérez, Helmut F. Erbersdobler, M.C. Terroba, Feng Gao, J.C. Galofré, Jae-Youn Kim, Masoumeh Sadeghi, G. Oriani, Hemlata R. Yadav, A.J.B. Oliveira, S. Verwied-Jorky, Elzbieta Sochacka-Tatara, Jesús Valdés Flores, Abdelmonem S. Hassan, F. Guillen-Grima, Samer A. Al Baz, Vaishali Taralekar, Aisha Al-Kubaisi, A.C. Silva, Luis Ortiz-Hernández, R. Cammarata, V. Dolz, Elizabeth Halley-Castillo, M. Amini, Tamás Decsi, Amit Abraham, Martin Gotteland, A.A.J. Quadros, G. Salvatori, Aleksander Galas, C. Abreu, Kamini Dangat, Basma Basha, Amjad H. Jarrar, L. Sacchetti, Wieslaw Jedrychowski, Wissam H. Ibrahim, T. Martin, Grażyna Sygitowicz, P. Pujante, Gerardo Guiter, J.C. Díaz-Montiel, Ferdinand Haschke, Yunfei Cao, R. Bracale, Nancy Paulina López Olmedo, Juan O Talavera, Agnieszka Pac, G. Frühbeck, Alison E. Harvey, Savita Mehendale, Anne Noatsch, Zengnan Mo, Marcellina Mian, Sylvia Cruchet, Klaus Eder, S. Santos, G. Labruna, Veronika Somoza, Sarah Egert, F. Shojaee-Moradie, J.V. Bargieri, Umberto Maugeri, Young-Hoon Yang, J. Salvador, F. Salarifar, Mirosław Jarosz, Manfred Fobker, C. Nardelli, Jina Hong, Mariam Al-Ali, Ihab Tewfik, Ursel Wahrburg, D. Pacheco, Chong-Eon Lee, Roberto Dias Batista Pereira, Edgar Denova-Gutiérrez, Roberto Medina-Santillán, Anitha Kilari, M. Trak-Fellermeier, Julia Spielmann, Maricarmen Teresa Genis Gómez, Oscar Brunser, Manuel González-Ortiz, C. Franke, Sadhana Joshi, Jorge Salmerón, Tamara Lewis, Berthold Koletzko, D.A. de Luis, Corinna Brandsch, F. Contaldo, Omar Jacques-Camarena, J.F. Pariz López-Madrueño, Daniel Diaz, Kyu-Il Kim, Amer Alsaied, P. Buono, Gerardo Huitrón-Bravo, Dulce Paola Melchor López, Gaby Andersen, L. Cuellar, Grażyna Nowicka, O. Izaola, Nomeli P. Nunez, Danuta Zapolska-Downar, C. Finelli, Alejandra Jiménez-Aguilar, Hosam M. Habib, Esperanza Martínez-Abundis, M. Siavash, Abdulbari Bener, and Choong-Nam Kim

Subjects
Gerontology, Nutrition and Dietetics, Index (economics), business.industry, Medicine (miscellaneous), Medicine, Subject (documents), business
Published
2008

6. Acknowledgement to the 2008 Reviewers

Author

G. Salvatori, Grażyna Nowicka, Gerardo Guiter, Juan O Talavera, Manuel González-Ortiz, O. Izaola, Sadhana Joshi, J.C. Díaz-Montiel, Tamara Lewis, Yunfei Cao, Roberto Medina-Santillán, Zengnan Mo, J.C. Galofré, Tamás Decsi, Abdelmonem S. Hassan, Marcellina Mian, Claude Bachmann, D. Pineda-Pérez, Sylvia Cruchet, R. Cammarata, Maricarmen Teresa Genis Gómez, S. Verwied-Jorky, J.F. Pariz López-Madrueño, M. Amini, F. Shojaee-Moradie, J.V. Bargieri, Gaby Andersen, Amjad H. Jarrar, G. Oriani, Anitha Kilari, Luis Ortiz-Hernández, Oscar Brunser, L. Cuellar, Marise Lazaretti-Castro, Yinglong Xu, Rebekah R. Smith, Corinna Brandsch, Wissam H. Ibrahim, S. Santos, Samer A. Al Baz, Vaishali Taralekar, Mirosław Jarosz, Aisha Al-Kubaisi, T. Martin, Grażyna Sygitowicz, Amit Abraham, Wieslaw Jedrychowski, C. Abreu, Daniel Diaz, Jesús Valdés Flores, Ferdinand Haschke, Elzbieta Sochacka-Tatara, J. Salvador, Chong-Eon Lee, Kyu-Il Kim, V. Dolz, Choong-Nam Kim, Nancy Paulina López Olmedo, F. Salarifar, Elizabeth Halley-Castillo, Agnieszka Pac, C. Nardelli, Jina Hong, Martin Gotteland, M. Trak-Fellermeier, L. Sacchetti, Hemlata R. Yadav, Julia Spielmann, Young-Hoon Yang, Tingna Lu, R. Bracale, Klaus Eder, F. Guillen-Grima, P. Pujante, Savita Mehendale, A.A.J. Quadros, Berthold Koletzko, Umberto Maugeri, G. Frühbeck, M.C. Terroba, G. Labruna, Manfred Fobker, Roberto Dias Batista Pereira, Dulce Paola Melchor López, Feng Gao, Mariam Al-Ali, Cristina Campoy, Aleksander Galas, Gabriele I. Stangl, A.J.B. Oliveira, Elisabeth Haschke-Becher, A. Daniele, F. Pasanisi, Helmut F. Erbersdobler, Jae-Youn Kim, Masoumeh Sadeghi, G. Calcagno, P. Buono, Gerardo Huitrón-Bravo, Kamini Dangat, Alison E. Harvey, Veronika Somoza, Sarah Egert, Anne Noatsch, Basma Basha, A.C. Silva, Amer Alsaied, Alejandra Jiménez-Aguilar, Hosam M. Habib, Ihab Tewfik, Ursel Wahrburg, D. Pacheco, Edgar Denova-Gutiérrez, Abdulbari Bener, Esperanza Martínez-Abundis, C. Franke, Jorge Salmerón, M. Siavash, D.A. de Luis, F. Contaldo, Omar Jacques-Camarena, Nomeli P. Nunez, Danuta Zapolska-Downar, and C. Finelli

Subjects
Gerontology, medicine.medical_specialty, Medical education, Nutrition and Dietetics, business.industry, Acknowledgement, Alternative medicine, Medicine (miscellaneous), Medicine, business
Published
2008

7. NuGO Society News

Author

Elisabeth Haschke-Becher, Mariam Al-Ali, A. Daniele, Savita Mehendale, A.C. Silva, Marise Lazaretti-Castro, Yinglong Xu, M. Amini, Wissam H. Ibrahim, Rebekah R. Smith, Ferdinand Haschke, Umberto Maugeri, Roberto Medina-Santillán, Claude Bachmann, D. Pineda-Pérez, L. Sacchetti, Dulce Paola Melchor López, Julia Spielmann, G. Calcagno, Manuel González-Ortiz, Abdulbari Bener, Alison E. Harvey, Sadhana Joshi, Tamara Lewis, Hemlata R. Yadav, C. Franke, Maricarmen Teresa Genis Gómez, C. Nardelli, F. Guillen-Grima, Young-Hoon Yang, Amer Alsaied, Sylvia Cruchet, S. Santos, Jorge Salmerón, F. Shojaee-Moradie, P. Buono, Gerardo Huitrón-Bravo, Oscar Brunser, D.A. de Luis, J.V. Bargieri, Veronika Somoza, Luis Ortiz-Hernández, Sarah Egert, Corinna Brandsch, Alejandra Jiménez-Aguilar, Daniel Diaz, Jesús Valdés Flores, Wieslaw Jedrychowski, Anitha Kilari, Elizabeth Halley-Castillo, J. Salvador, Kyu-Il Kim, Ihab Tewfik, Ursel Wahrburg, F. Pasanisi, Amit Abraham, D. Pacheco, J.C. Galofré, Hosam M. Habib, Gaby Andersen, Edgar Denova-Gutiérrez, F. Salarifar, Helmut F. Erbersdobler, Nancy Paulina López Olmedo, C. Abreu, Mirosław Jarosz, Aisha Al-Kubaisi, L. Cuellar, Jina Hong, Jae-Youn Kim, T. Martin, Grażyna Sygitowicz, Chong-Eon Lee, Aleksander Galas, Masoumeh Sadeghi, Esperanza Martínez-Abundis, Abdelmonem S. Hassan, Samer A. Al Baz, F. Contaldo, M. Siavash, Kamini Dangat, Vaishali Taralekar, R. Cammarata, R. Bracale, Nomeli P. Nunez, Danuta Zapolska-Downar, Grażyna Nowicka, J.F. Pariz López-Madrueño, C. Finelli, Omar Jacques-Camarena, Martin Gotteland, Gerardo Guiter, Amjad H. Jarrar, Agnieszka Pac, Berthold Koletzko, O. Izaola, M. Trak-Fellermeier, Anne Noatsch, Juan O Talavera, A.J.B. Oliveira, G. Frühbeck, Klaus Eder, G. Labruna, Manfred Fobker, Tamás Decsi, Roberto Dias Batista Pereira, Feng Gao, G. Salvatori, J.C. Díaz-Montiel, Yunfei Cao, Zengnan Mo, Marcellina Mian, G. Oriani, Elzbieta Sochacka-Tatara, P. Pujante, M.C. Terroba, A.A.J. Quadros, Cristina Campoy, Gabriele I. Stangl, Basma Basha, S. Verwied-Jorky, V. Dolz, Choong-Nam Kim, and Tingna Lu

Subjects
Gerontology, Medical education, Nutrition and Dietetics, business.industry, Medicine (miscellaneous), Medicine, business
Published
2008

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