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Abstract Aim To evaluate the late‐onset post‐traumatic stress disorder (PTSD) situation, coping strategies and social supports for frontline clinical nurses 6 months after involvement in fighting against coronavirus disease 2019 (COVID–19) outbreak in China. Design A cross‐sectional design. Methods We recently randomly distributed a questionnaire online to Chinese nurses who had taken care of COVID‐19 patients since the end of January 2020. The questionnaire was made up of three professional scales, the impact of event scale‐revised, simplified coping style questionnaire and social support rating scale included. Results The general prevalence of late‐onset PTSD among frontline nurses was 88.19%. Nurses who worked in Hubei Province (the kindle place of the COVID‐19 outbreak) showed lower risk of late‐onset PTSD symptoms than those who did not. We also found that positive coping strategies were correlated with less late‐onset PTSD symptoms. Meanwhile, getting more social supports could help these nurses to obtain positive coping strategies.