1. Preeclampsia and future cardiovascular risk: A point of view from the clearance of plasma vasoactive amines.
- Author
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Zhou SS, Zhou YM, Li D, and Chen NN
- Subjects
- Cardiovascular Diseases blood, Female, Humans, Menstruation blood, Pregnancy, Risk Factors, Cardiovascular Diseases etiology, Histamine blood, Norepinephrine blood, Pre-Eclampsia blood, Serotonin blood
- Abstract
Objective: To summarize the reported evidence on the relationship between vasoactive amines and preeclampsia., Methods: A literature search was conducted in MEDLINE/PubMed and EMBASE., Results: The summarized results are as follows: (1) Menstruation can effectively eliminate vasoactive amines norepinephrine, serotonin and histamine. (2) Pregnancy increases norepinephrine production due to fetal brain development and decreases vasoactive-amine elimination due to amenorrhea. (3) Preeclampsia is associated with a low renal and/or sweating capacity, or in rare cases, with increased norepinephrine production due to maternal pheochromocytoma and fetal neuroblastoma., Conclusion: Preeclampsia is mainly due to decreased excretion of norepinephrine and other vasoactive amines.
- Published
- 2016
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