1. Stretchable and Photocatalytically Renewable Electrochemical Sensor Based on Sandwich Nanonetworks for Real-Time Monitoring of Cells.
- Author
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Wang YW, Liu YL, Xu JQ, Qin Y, and Huang WH
- Subjects
- Catalysis, Gold chemistry, Human Umbilical Vein Endothelial Cells metabolism, Humans, Mast Cells metabolism, Nanotubes chemistry, Nanowires chemistry, Nitric Oxide metabolism, Particle Size, Photochemical Processes, Receptor, Serotonin, 5-HT1D metabolism, Surface Properties, Time Factors, Titanium chemistry, Biosensing Techniques, Electrochemical Techniques, Human Umbilical Vein Endothelial Cells chemistry, Mast Cells chemistry, Nitric Oxide analysis, Receptor, Serotonin, 5-HT1D analysis
- Abstract
Stretchable electrochemical (EC) sensors have broad prospects in real-time monitoring of living cells and tissues owing to their excellent elasticity and deformability. However, the redox reaction products and cell secretions are easily adsorbed on the electrode, resulting in sensor fouling and passivation. Herein, we developed a stretchable and photocatalytically renewable EC sensor based on Au nanotubes (NTs) and TiO
2 nanowires (NWs) sandwich nanonetworks. The external Au NTs are used for EC sensing, and internal TiO2 NWs provide photocatalytic performance to degrade contaminants, which endows the sensor with excellent EC performance, high photocatalytic activity, and favorable mechanical tensile property. This allows highly sensitive recycling monitoring of NO released from endothelial cells and 5-HT released from mast cells under their stretching states in real time, therefore providing a promising tool to unravel elastic and mechanically sensitive cells, tissues, and organs.- Published
- 2018
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