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5 results on '"PAPA, IRENE"'

1. Assessing risks of leaving the umbilical cord uncut: A case–control study.

Author

Bedetti, Luca, Zinani, Isotta, Lugli, Licia, Iughetti, Lorenzo, Facchinetti, Fabio, Loizzo, Vitaliana, Bianco, Valentina, Martignoni, Laura, Papa, Irene, Bonvicini, Chiara, Rizzo, Vittoria, Capuano, Ciro, and Berardi, Alberto

Subjects
UMBILICAL cord, NEONATAL sepsis, CASE-control method, NEONATAL intensive care units, URINARY tract infections
Abstract

Keywords: lotus birth; neonatal care; newborn; sepsis; umbilical cord nonseverance EN lotus birth neonatal care newborn sepsis umbilical cord nonseverance 2378 2380 3 10/11/23 20231101 NES 231101 A lotus birth is when the umbilical cord remains connected to the placenta until separation occurs naturally.[1] The benefits have not been demonstrated, but the risks can include systemic infections, as the tissue becomes colonised by multiple bacteria.[1] Some case reports have documented omphalitis, bacteraemia, urinary tract infections and hepatitis,[[1], [3]] but the study designs did not enable causal associations to be established. Lotus birth, neonatal care, newborn, sepsis, umbilical cord nonseverance Assessing risks of leaving the umbilical cord uncut: A case-control study. [Extracted from the article]

Published
2023
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2. Maternal Carriage in Late-Onset Group B Streptococcus Disease, Italy.

Author

Berardi, Alberto, Spada, Caterina, Creti, Roberta, Auriti, Cinzia, Gambini, Lucia, Rizzo, Vittoria, Capretti, Mariagrazia, Laforgia, Nicola, Papa, Irene, Tarocco, Anna, Lanzoni, Angela, Biasucci, Giacomo, Piccinini, Giancarlo, Nardella, Giovanna, Latorre, Giuseppe, Merazzi, Daniele, Travan, Laura, Letizia, Maria, Reggiani, Bacchi, and Baroni, Lorenza

Abstract

We retrospectively investigated mother-to-infant transmission of group B Streptococcus (GBS) in 98 cases of lateonset disease reported during 2007-2018 by a network in Italy. Mothers with full assessment of vaginal/rectal carriage tested at prenatal screening (APS) and at time of late onset (ATLO) were included. Thirty-three mothers (33.7%) were never GBS colonized; 65 (66.3%) were vaginal/rectal colonized, of which 36 (36.7%) were persistently colonized. Mothers with vaginal/rectal colonization ATLO had high rates of GBS bacteriuria (33.9%) and positive breast milk culture (27.5%). GBS strains from mother-infant pairs were serotype III and possessed the surface protein antigen Rib. All but 1 strain belonged to clonal complex 17. GBS strains from 4 mother-infant pairs were indistinguishable through pulsed-field gel electrophoresis. At least two thirds of late-onset cases are transmitted from mothers, who often have vaginal/rectal carriage, positive breast milk culture, or GBS bacteriuria, which suggests heavy maternal colonization. [ABSTRACT FROM AUTHOR]

Published
2021
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3. Stewardship antimicrobica nel neonato e nel piccolo lattante: Perché e come praticarla

Author

Berardi, Alberto, Ficara, Monica, Pietrella, Elisa, Boncompagni, Alessandra, Toffoli, Carlotta, Bianchini, Anastasia, Della Casa, Elisa, Spada, Caterina, Spaggiari, Eugenio, Ciccia, Matilde, Gargano, Giancarlo, Rizzo, Vittoria, Azzalli, Milena, Biasucci, Giacomo, Gambini, Lucia, Bolognesi, Serenella, Ferrari, Fabrizio, Memo, L., Nicolini, G., Ciccia, M., Sandri, F., Capretti, M. G., Dondi, A., Pasini, L., Ragni, L., Albarelli, A., Fiorini, V., Giugno, C., Lanzoni, P., Di Grande, E., Polese, A., China, M. C., Rizzo, V., Stella, M., Zucchini, A., Malaguti, L., Azzalli, M., Garani, G., Nasi, S., Bacchini, P., Fragni, G., Baldassarri, P., Pulvirenti, R. M., Valletta, E., Bidetti, M. L., Incerti, S. Storchi, Di Carlo, C., Lanzoni, A., Serra, L., Silvestrini, D., Berardi, A., Ferrari, F., Lugli, L., Venturelli, C., Sarti, M., Volta, A., Dodi, I., Magnani, C., Guidi, B., Biasucci, G., Chiarabini, R., De Paulis, N., Padrini, D., Riboni, S., Pedna, M. F., Casadio, L., Marchetti, F., Muratori, C., Piccinini, G., Renzelli, C., Amarri, S., Baroni, L., Carretto, E., Gargano, G., Pedori, S., Riva, M., Zuelli, C., Ancona, G., Bolognesi, S., Vergine, G., Viola, L., Chiossi, C., Pagano, R., Zanacca, C., Palmieri, R., PICCININI, GIANCARLO, BASTELLI, ANNALISA, AMBRETTI, SIMONE, CORVAGLIA, LUIGI TOMMASO, LANARI, MARCELLO, LAMA, CARLA, VENTUROLI, VINCENZO, ALESSANDRINI, CATERINA, FACCHINETTI, FABRIZIO, GAMBINI, LUIGI, BERTELLI, MICHELE, SAMBRI, VITTORIO, FORNACIARI, SILVIA, PAPA, IRENE, RIVI, CLAUDIA, BONVICINI, CARLOTTA, Berardi, Alberto, Ficara, Monica, Pietrella, Elisa, Boncompagni, Alessandra, Toffoli, Carlotta, Bianchini, Anastasia, Della Casa, Elisa, Spada, Caterina, Spaggiari, Eugenio, Ciccia, Matilde, Gargano, Giancarlo, Rizzo, Vittoria, Azzalli, Milena, Biasucci, Giacomo, Gambini, Lucia, Bolognesi, Serenella, Piccinini, Giancarlo, Ferrari, Fabrizio, Memo, L., Nicolini, G., Ciccia, M., Bastelli, A., Sandri, F., Ambretti, S., Capretti, M. G., Corvaglia, L., Dondi, A., Lanari, M., Pasini, L., Ragni, L., Albarelli, A., Fiorini, V., Giugno, C., Lanzoni, P., Di Grande, E., Polese, A., China, M. C., Rizzo, V., Stella, M., Zucchini, A., Malaguti, L., Azzalli, M., Garani, G., Lama, C., Nasi, S., Bacchini, P., Fragni, G., Baldassarri, P., Pulvirenti, R. M., Valletta, E., Venturoli, V., Alessandrini, C., Bidetti, M. L., Incerti, S. Storchi, Di Carlo, C., Lanzoni, A., Serra, L., Silvestrini, D., Berardi, A., Facchinetti, F., Ferrari, F., Lugli, L., Venturelli, C., Sarti, M., Volta, A., Dodi, I., Gambini, L., Magnani, C., Guidi, B., Bertelli, M., Biasucci, G., Chiarabini, R., De Paulis, N., Padrini, D., Riboni, S., Pedna, M. F., Sambri, V., Casadio, L., Marchetti, F., Muratori, C., Piccinini, G., Renzelli, C., Amarri, S., Baroni, L., Carretto, E., Fornaciari, S., Gargano, G., Pedori, S., Riva, M., Zuelli, C., Ancona, G., Bolognesi, S., Papa, I., Vergine, G., Viola, L., Chiossi, C., Pagano, R., Rivi, C., Zanacca, C., Bonvicini, C., and Palmieri, R.

Subjects
Sepsi, Pediatrics, Perinatology and Child Health, Antibiotic, Antimicrobial stewardship, Prophylaxi, Infection, Newborn
Abstract

Antimicrobial resistances are increasing worldwide, due to the misuse of antibiotic therapies in humans as well as in animals. It is expected that within a few decades multi-resistant pathogens will become the leading cause of death worldwide. The misuse of antibiotics in the neonatal period depends on the lack of predictive diagnostic tests and the peculiarity of symptoms of sepsis, which frequently are vague and unspecific at the time of presentation. Policies to prevent the emergence of antimicrobial resistances rely on a judicious use of antibiotics, on protocols and additional measures shared by health care providers. This document summarizes recent indications issued in the Emilia-Romagna subsequent to a review of the literature.

Published
2017

4. An area-based study on intrapartum antibiotic prophylaxis for preventing group B streptococcus early-onset disease: advances and limitations.

Author

Berardi, Alberto, Rossi, Cecilia, Bacchi Reggiani, Maria Letizia, Bastelli, Annalisa, Capretti, Maria Grazia, Chiossi, Claudio, Fiorini, Valentina, Gambini, Lucia, Gavioli, Sara, Lanari, Marcello, Memo, Luigi, Papa, Irene, Pini, Luana, Rizzo, Maria Vittoria, Zucchini, Andrea, Facchinetti, Fabio, and Ferrari, Fabrizio

Subjects
STREPTOCOCCUS, PREVENTIVE medicine, FEMALES, STREPTOCOCCACEAE, STREPTOCOCCAL disease prevention, ANTIBIOTICS, PREMATURE infants, MATERNAL health services, MEDICAL protocols, RECTUM, STREPTOCOCCAL diseases, VAGINA, RETROSPECTIVE studies, VERTICAL transmission (Communicable diseases), AMPICILLIN, ANTIBIOTIC prophylaxis, INFECTIOUS disease transmission
Abstract

Introduction: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking.Materials and Methods: This was a 3-month retrospective area-based study including all regional deliveries  ≥35 weeks' gestation (in 2012). The sensitivity, specificity, positive and negative predictive values, odds ratio and receiver operating characteristic (ROC) curve for intrapartum antibiotic prophylaxis (IAP) among full-term and preterm deliveries and prolonged membrane rupture (PROM) were calculated.Results: Among 7133 women, 259 (3.6%) were preterm (35-36 weeks' gestation). Full-term women were 6874, and 876 (12.7%) had at least 1 RF. Most women (6495) had prenatal screening and 21.4% (1390) were GBS positive. IAP was given to 2369 (33.2%) women (preterm, n = 166; full term, n = 2203). Compared to full-term, preterm women were less likely to receive IAP when indicated (73.2% versus 90.3%, p < 0.01). Full-term women represented the largest area under the curve (AUC, 0.87). PROM showed the highest sensitivity (98.6%), but the lowest specificity (6.9%) and AUC (0.53).Conclusions: Large-scale prenatal screening and IAP are feasible. Women delivering preterm are less likely to receive IAP when indicated. Most unnecessary antibiotics are given in cases of PROM. [ABSTRACT FROM AUTHOR]

Published
2017
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5. An area-based study on intrapartum antibiotic prophylaxis for preventing group B streptococcus early-onset disease: advances and limitations

Author

Luana Pini, Lucia Gambini, Alberto Berardi, Fabio Facchinetti, Irene Papa, Claudio Chiossi, Maria Grazia Capretti, Valentina Fiorini, Luigi Memo, Fabrizio Ferrari, Maria Letizia Bacchi Reggiani, Maria Vittoria Rizzo, Andrea Zucchini, Marcello Lanari, Cecilia Rossi, Annalisa Bastelli, Sara Gavioli, Berardi, Alberto, Rossi, Cecilia, Bacchi Reggiani, Maria Letizia, Bastelli, Annalisa, Capretti, Maria Grazia, Chiossi, Claudio, Fiorini, Valentina, Gambini, Lucia, Gavioli, Sara, Lanari, Marcello, Memo, Luigi, Papa, Irene, Pini, Luana, Rizzo, Maria Vittoria, Zucchini, Andrea, Facchinetti, Fabio, and Ferrari, Fabrizio

Subjects
medicine.medical_specialty, Group B streptococcus, Prom, Group B, sepsis, 03 medical and health sciences, 0302 clinical medicine, prevention, newborn, Pregnancy, Risk Factors, intrapartum antibiotic prophylaxis, risk factors, 030225 pediatrics, Positive predicative value, Streptococcal Infections, Medicine, Humans, 030212 general & internal medicine, Antibiotic prophylaxis, Full Term, Retrospective Studies, Group B streptococcu, Receiver operating characteristic, business.industry, Obstetrics, Rectum, Obstetrics and Gynecology, Odds ratio, Antibiotic Prophylaxis, Infectious Disease Transmission, Vertical, Anti-Bacterial Agents, Perinatal Care, intrapartum antibiotic prophylaxi, risk factor, Pediatrics, Perinatology and Child Health, Vagina, Gestation, Premature Birth, Ampicillin, Female, Guideline Adherence, business
Abstract

INTRODUCTION: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking. MATERIALS AND METHODS: This was a 3-month retrospective area-based study including all regional deliveries ≥35 weeks' gestation (in 2012). The sensitivity, specificity, positive and negative predictive values, odds ratio and receiver operating characteristic (ROC) curve for intrapartum antibiotic prophylaxis (IAP) among full-term and preterm deliveries and prolonged membrane rupture (PROM) were calculated. RESULTS: Among 7133 women, 259 (3.6%) were preterm (35-36 weeks' gestation). Full-term women were 6874, and 876 (12.7%) had at least 1 RF. Most women (6495) had prenatal screening and 21.4% (1390) were GBS positive. IAP was given to 2369 (33.2%) women (preterm, n = 166; full term, n = 2203). Compared to full-term, preterm women were less likely to receive IAP when indicated (73.2% versus 90.3%, p

Published
2016

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