1. Delusional Belief induced by clomiphene treatment
- Author
-
Grimm, Dr. Oliver and Hubrich, Dr. Petra
- Subjects
Neuroscience: Neuropsychiatry ,Neuropsychiatry - Abstract
We report the case of a 35 year old women who developed a complex paranoid delusion during the course of clomiphene treatment für ovulation. The psychopathology was remarkable, because after a short hypomanic period the patient was without severe cognitive disturbance but struggled with a complex monothematic delusion. The delusion vanished in the course of a combination treatment with olanzapine a cognitive behavioral therapy. We could not entirely rule out the possibility of an endogenous psychiatric disease but nevertheless we encountered an unusual monothematic delusion which showed a strong temporal correlation with the intake of clomiphene. We provide some speculation about underlying neurobiological mechanisms on the basis of the dopamine theory of delusion.
- Published
- 2006