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Objectives: We aimed to investigate the effect of sugammadex on the motor, sensory and deep sensory block in the sciatic nerve created by bupivacaine in rats., Materials and Methods: 18 Sprague-Dawley adult male rats treated with unilateral sciatic nerve block by bupivacaine (0.2 ml) were randomly divided into three groups. Control group (Group C, n = 6, 1.5 mL saline) perineural sugammadex group (Group PNS, n = 6, 16 mg/kg) and intraperitoneal sugammadex group (Group IPS, n = 6, 16 mg/kg) Motor, sensory, and deep sensory functions were evaluated every 10 minutes by a blind researcher. 6 tissue samples each belonging to the sciatic nerve, 1.5 cm in length and 0.2 cm in diameter, were taken from paraffin blocks. Sections of 3-4 micrometers were stained with Hematoxylin + Eosin, Masson Trichrome dyes and examined under a light microscope., Results: There was no statistically significant difference between 3 groups in terms of the time to return to normal motor, sensory and deep sensory function. There was also no significant difference in edema, extracellular matrix, and myelin. Inflammatory cells were seen in all groups, mainly epineurium, epineurium, and perineurium., Conclusion: There are findings of no histological effects or effects on local block of sugammadex in rats undergoing sciatic nerve block.

Objective: To evaluate the suitability of spinal and general anaesthesia for cesarean section., Methods: The prospective, double-blinded study, done between March and December 2009, at Central Education and Research Hospital, Erzurum, Turkey, involved 60 patients undergoing elective cesarean surgery. They were grouped according to the kind of anaesthesia, with each group having 30 patients each. Postoperative pain scores, opioid requirement, side effects and patient satisfaction were compared through statistical analysis using SPSS version 10., Results: Patient demographics were similar in both groups. Patients in the general anaesthesia group consumed 638.4 +/- 179.10 microg fentanyl, while patients in the spinal anaesthesia group consumed 356.3 +/- 87.1 microg. The number of patients requiring opioid via Patient Controlled Analgesia in the first 24 hours was significantly higher in the general anaesthesia group. Patient satisfaction was significantly higher in the spinal anaesthesia group., Conclusion: Type of anaesthesia for elective cesarean section is important to provide sufficient post-operative analgesia and patient satisfaction.

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