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4 results on '"Olugbade, K."'

1. Patient-Reported Quality of Life and Convalescence After Minimally Invasive Kidney Cancer Surgery.

Author

Althaus AB, Chang P, Mao J, Olugbade K, Taylor K, Dewey L, Percy A, Crociani C, McNally K, and Wagner AA

Subjects
Adult, Aged, Counseling, Female, Humans, Kidney Neoplasms psychology, Male, Middle Aged, Nephrectomy methods, Patient Satisfaction, Prospective Studies, Quality of Life, Time Factors, Convalescence psychology, Kidney Neoplasms surgery, Laparoscopy adverse effects, Nephrectomy adverse effects, Patient Reported Outcome Measures
Abstract

Objective: To better characterize recovery after minimally invasive kidney surgery, we present a study describing patient-reported health-related quality of life (HRQOL) following minimally invasive radical nephrectomy (RN) and partial nephrectomy (PN)., Methods: Patients who underwent minimally invasive PN or RN for renal cancer were invited to enroll in a prospective, patient-reported HRQOL study using the Convalescence and Recovery Evaluation (CARE) instrument and Short Form-12. Patients completed questionnaires at baseline, 2, 4, 8, and 12 weeks after surgery. Mixed repeated measures model were used to assess time effect on HRQOL scores and predictors of scores within each surgery groups., Results: One hundred seventy-seven patients were included in the study: 50 had RN and 127 had PN. At 2 weeks, both groups had significant decreases in Overall CARE, as well as the Pain, Gastrointestinal, and Activity domain scores which remained slightly below baseline at 4 weeks. At 4 weeks only 50% of patients in both the RN and PN cohorts returned to baseline overall CARE score. By 12 weeks 82% returned to baseline overall CARE score in the RN group while 76% of patients did so in the PN group., Conclusion: Convalescence after minimally invasive renal surgery can often extend beyond 4 weeks post-treatment in PN and RN subjects. This information may be used to provide more accurate preoperative counseling in an attempt to improve overall patient satisfaction., (Copyright © 2020 Elsevier Inc. All rights reserved.)

Published
2020
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2. Predictors of 30-day acute kidney injury following radical and partial nephrectomy for renal cell carcinoma.

Author

Schmid M, Abd-El-Barr AE, Gandaglia G, Sood A, Olugbade K Jr, Ruhotina N, Sammon JD, Varda B, Chang SL, Kibel AS, Chun FK, Menon M, Fisch M, and Trinh QD

Subjects
Adolescent, Adult, Aged, Carcinoma, Renal Cell pathology, Female, Humans, Kidney Neoplasms pathology, Male, Middle Aged, Nephrectomy methods, Prognosis, Treatment Outcome, Young Adult, Acute Kidney Injury etiology, Carcinoma, Renal Cell surgery, Kidney Neoplasms surgery, Nephrectomy adverse effects
Abstract

Introduction: Patients with renal cell carcinoma who were treated with radical nephrectomy (RN) or partial nephrectomy (PN) are at risk of postoperative acute kidney injury (AKI), and in consequence, short- and long-term adverse outcomes. We sought to identify independent predictors of 30-day AKI in patients undergoing RN or PN., Materials and Methods: Between 2005 and 2011, patients who underwent RN or PN for renal cell carcinoma within the National Surgical Quality Improvement Program data set were identified. Patients with preexisting severe renal failure, defined as a preoperative estimated glomerular filtration rate<30 ml/min/1.73 m(2), were excluded from the analyses. AKI was defined as an elevation of serum creatinine>2mg/dl above baseline or the need for dialysis within 30 days of surgery. Univariable and multivariable logistic regression analyses were used to examine the association between preoperative factors and the risk of postoperative AKI., Results: Overall, 1,944 (58.6%) and 1,376 (41.4%) patients underwent RN and PN, respectively. Overall, 1.8% of the patients included in the study experienced AKI within an average of 5.4 days after RN or PN. Independent predictors for AKI included obesity (odds ratio [OR] = 2.24, P = 0.04), history of neurovascular disease (OR = 5.29, P<0.001), and a preoperative chronic kidney disease stage II (OR = 10.00, P = 0.03) or stage III (OR = 26.49, P = 0.02). Furthermore, RN (OR = 2.87, P = 0.02) or the open approach (OR = 2.18, P = 0.04) was significantly associated with postoperative AKI. AKI was significantly associated with adverse postoperative outcomes, such as prolonged length of stay, occurrence of any complication, and mortality (all P <0.001)., Conclusions: The assessment of preoperative kidney function and comorbidity status is essential to identify patients at risk of postoperative AKI. In addition to preoperative chronic kidney disease stages II and III, neurovascular disease, obesity, and surgical approach (RN or open) represent predictors of 30-day AKI. Careful patient selection as well as preoperative planning may help reduce this unfavorable postoperative outcome., (Copyright © 2014 Elsevier Inc. All rights reserved.)

Published
2014
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3. Predictors of 30-day acute kidney injury following radical and partial nephrectomy for renal cell carcinoma

Author

Briony Varda, Giorgio Gandaglia, Marianne Schmid, Nedim Ruhotina, Felix K.-H. Chun, Margit Fisch, Kola Olugbade, Quoc-Dien Trinh, Adam S. Kibel, Jesse D. Sammon, Akshay Sood, Mani Menon, Steven L. Chang, Abd El Rahman M Abd-El-Barr, Schmid, M, Abd-El-Barr, A, Gandaglia, G, Sood, A, Olugbade, K, Ruhotina, N, Sammon, Jd, Varda, B, Chang, Sl, Kibel, A, Chun, Fk, Menon, M, Fisch, M, and Trinh, Qd

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Urology, medicine.medical_treatment, Renal function, urologic and male genital diseases, Nephrectomy, Young Adult, Renal cell carcinoma, medicine, Humans, Carcinoma, Renal Cell, Dialysis, Aged, business.industry, Acute kidney injury, Odds ratio, Acute Kidney Injury, Middle Aged, medicine.disease, Prognosis, Comorbidity, Kidney Neoplasms, Surgery, Treatment Outcome, Oncology, Female, business, Kidney disease
Abstract

Introduction: Patients with renal cell carcinoma who were treated with radical nephrectomy (RN) or partial nephrectomy (PN) are at risk of postoperative acute kidney injury (AKI), and in consequence, short-and long-term adverse outcomes. We sought to identify independent predictors of 30-day AKI in patients undergoing RN or PN. Materials and methods: Between 2005 and 2011, patients who underwent RN or PN for renal cell carcinoma Within the National Surgical Quality Improvement Program data set were identified. Patients with preexisting severe renal failure, defined as a preoperative estimated glomerular filtration rate 2 mg/d1 above baseline or the need for dialysis within 30 days of surgery. Univariable and multivariable logistic regression analyses were used to examine the association between preoperative factors and the risk of postoperative AKI. Results: Overall, 1,944 (58.6%) and 1,376 (41.4%) patients underwent RN and PN, respectively. Overall, 1.8% of the patients included in the study experienced AKI within an average of 5.4 days after RN or PN. Independent predictors for AKI included obesity (odds ratio [OR] = 2.24, P = 0.04), history of neurovascular disease (OR = 5.29, P < 0.001), and a preoperative chronic kidney disease stage R (OR = 10.00, P = 0.03) or stage III (OR = 26.49, P = 0.02). Furthermore, RN (OR = 2.87, P = 0.02) or the open approach (OR = 2.18, P = 0.04) was significantly associated with postoperative AKI. AKI was significantly associated with adverse postoperative outcomes, such as prolonged length of stay, occurrence of any complication, and mortality (all P < 0.001). Conclusions: The assessment of preoperative kidney function and comorbidity status is essential to identify patients at risk of postoperative AKI. In addition to preoperative chronic kidney disease stages II and III, neurovascular disease, obesity, and surgical approach (RN or open) represent predictors of 30-day AKI. Careful patient selection as well as preoperative planning may help reduce this unfavorable postoperative outcome. (C) 2014 Elsevier Inc. All rights reserved.

Published
2014

4. The impact of resident involvement in minimally-invasive urologic oncology procedures

Author

Kevin C. Zorn, Jeffrey J. Leow, Nedim Ruhotina, Julien Dagenais, Firas Abdollah, Quoc-Dien Trinh, Akshay Sood, Kola Olugbade, Briony Varda, Adam S. Kibel, Jesse D. Sammon, Arun Rai, Steven L. Chang, Mani Menon, Giorgio Gandaglia, Marianne Schmid, Ruhotina, N, Dagenais, J, Gandaglia, G, Sood, A, Abdollah, F, Chang, Sl, Leow, Jj, Olugbade, K, Rai, A, Sammon, Jd, Schmid, M, Varda, B, Zorn, Kc, Menon, M, Kibel, A, and Trinh, Qd

Subjects
medicine.medical_specialty, business.industry, Prostatectomy, Urology, medicine.medical_treatment, General surgery, MEDLINE, Urologic Oncology, Odds ratio, Logistic regression, Nephrectomy, Surgery, Oncology, Medicine, Observational study, business, Complication, Original Research
Abstract

Introduction: Robotic and laparoscopic surgical training is an integral part of resident education in urology, yet the effect of resident involvement on outcomes of minimally-invasive urologic procedures remains largely unknown. We assess the impact of resident participation on surgical outcomes using a large multi-institutional prospective database.Methods: Relying on the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) Participant User Files (2005-2011), we abstracted the 3 most frequently performed minimally-invasive urologic oncology procedures. These included radical prostatectomy, radical nephrectomy and partial nephrectomy. Multivariable logistic regression models were constructed to assess the impact of trainee involvement (PGY 1-2: junior, PGY 3-4: senior, PGY ≥5: chief) versus attending-only on operative time, length-of-stay, 30-day complication, reoperation and readmission rates.Results: A total of 5459 minimally-invasive radical prostatectomies,1740 minimally-invasive radical nephrectomies and 786 minimally-invasive partial nephrectomies were performed during the study period, for which data on resident surgeon involvement was available. In multivariable analyses, resident involvement was not associated with increased odds of overall complications, reoperation, or readmission rates for minimally-invasive prostatectomy, radical and partial nephrectomy. However, operative time was prolonged when residents were involved irrespective of the type of procedure. Length-of-stay was decreased with senior resident involvement in minimally-invasive partial nephrectomies (odds ratio [OR] 0.49, p = 0.04) and prostatectomies (OR 0.68, p = 0.01). The major limitations of this study include its retrospective observational design, inability to adjust for the case complexity and surgeon/hospital characteristics, and the lack of information regarding the minimally-invasive approach utilized (whether robotic or laparoscopic).Conclusions: Resident involvement is associated with increased operative time in minimally-invasive urologic oncology procedures. However, it does not adversely affect the complication, reoperation or readmission rates, as well as length-of-stay.

Published
2014

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