1. Sulfemodin 8-O-β-<scp>d</scp>-Glucoside, a New Sulfated Anthraquinone Glycoside, and Antioxidant Phenolic Compounds from Rheum emodi
- Author
-
Riddhi Pradhan, B. Kopp, Beate Bahr, Klaus K. Mayer, Liselotte Krenn, D. H. Paper, and Armin Presser
- Subjects
DPPH ,Pharmaceutical Science ,Anthraquinones ,Plant Roots ,Antioxidants ,Analytical Chemistry ,Inhibitory Concentration 50 ,chemistry.chemical_compound ,Nepal ,Picrates ,Glucoside ,Drug Discovery ,Organic chemistry ,Glycosides ,Phenols ,Rheum ,Nuclear Magnetic Resonance, Biomolecular ,Benzofurans ,Pharmacology ,chemistry.chemical_classification ,Plants, Medicinal ,Molecular Structure ,biology ,Rheum emodi ,Biphenyl Compounds ,Organic Chemistry ,Glycoside ,biology.organism_classification ,Biphenyl compound ,Complementary and alternative medicine ,chemistry ,Molecular Medicine ,Emodin - Abstract
A sulfated emodin glucoside, emodin 8-O-beta-D-glucopyranosyl-6-O-sulfate (1), was isolated from the roots of Rheum emodi in an investigation of the active constituents of this Nepalese medicinal plant, and its structure was determined by spectroscopic and chemical methods. Additionally, two rare auronols, carpusin (2) and maesopsin (3), besides other anthraquinones and phenolics, were isolated and identified. Compounds 2 and 3 showed significant antioxidant activity in the DPPH assay, while chrysophanol, physcion, and emodin and their 8-O-glucosides were found to be inactive.
- Published
- 2003