1. Effects of diabetes on the development of radiation pneumonitis
- Author
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Wei Hou, Qiyao Zhao, Guangtong Dong, Yuxiao Li, Junping Wei, Bing Pang, and Xin Qi
- Subjects
0301 basic medicine ,Oncology ,medicine.medical_specialty ,medicine.medical_treatment ,Review ,Risk Assessment ,03 medical and health sciences ,Diseases of the respiratory system ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Diabetes mellitus ,Neoplasms ,medicine ,Diabetes Mellitus ,Animals ,Humans ,In patient ,Risk factor ,Adverse effect ,Radiation Pneumonitis ,RC705-779 ,business.industry ,Incidence (epidemiology) ,Incidence ,Diabetes ,Radiation pneumonia ,medicine.disease ,Prognosis ,Influence factors ,Radiation therapy ,Pneumonia ,Oxidative Stress ,030104 developmental biology ,030220 oncology & carcinogenesis ,Inflammation Mediators ,business ,Reactive Oxygen Species - Abstract
Radiation pneumonia (RP) is a common adverse reaction to radiation therapy in patients with chest tumors. Recent studies have shown that diabetes mellitus (DM), which can cause systemic multisystem damage, specifically targets lungs, and the incidence of RP in patients with a history of diabetes is higher than that in other patients with tumors who have undergone radiotherapy. DM is an important risk factor for RP in tumor patients undergoing RT, and patients with DM should be treated with caution. This article reviews research on the clinical aspects, as well as the mechanism, of the effects of diabetes on RP and suggests future research needed to reduce RP.
- Published
- 2021