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Life sciences research and experimentation are resource-intensive, requiring extensive trials and considerable time. Often, experiments do not achieve their intended objectives, but progress is made through trial and error, eventually leading to breakthroughs. Machine learning is transforming this traditional approach, providing methods to expedite processes and accelerate discoveries. Deep Learning is becoming increasingly prominent in chemistry, with Convolutional Graph Networks (CGN) being a key focus, though other approaches also show significant potential. This research explores the application of Natural Language Processing (NLP) to evaluate the effectiveness of chemical language representations, specifically SMILES and SELFIES, using tokenization methods such as Byte Pair Encoding (BPE) and a novel approach developed in this study, Atom Pair Encoding (APE), in BERT-based models. The primary objective is to assess how these tokenization techniques influence the performance of chemical language models in biophysics and physiology classification tasks. The findings reveal that APE, particularly when used with SMILES representations, significantly outperforms BPE by preserving the integrity and contextual relationships among chemical elements, thereby enhancing classification accuracy. Performance was evaluated in downstream classification tasks using three distinct datasets for HIV, toxicology, and blood-brain barrier penetration, with ROC-AUC serving as the evaluation metric. This study highlights the critical role of tokenization in processing chemical language and suggests that refining these techniques could lead to significant advancements in drug discovery and material science., (© 2024. The Author(s).)

Narratives posted on the internet by patients contain a vast amount of information about various concerns. This study aimed to extract multiple concerns from interviews with breast cancer patients using the natural language processing (NLP) model bidirectional encoder representations from transformers (BERT). A total of 508 interview transcriptions of breast cancer patients written in Japanese were labeled with five types of concern labels: "treatment," "physical," "psychological," "work/financial," and "family/friends." The labeled texts were used to create a multi-label classifier by fine-tuning a pre-trained BERT model. Prior to fine-tuning, we also created several classifiers with domain adaptation using (1) breast cancer patients' blog articles and (2) breast cancer patients' interview transcriptions. The performance of the classifiers was evaluated in terms of precision through 5-fold cross-validation. The multi-label classifiers with only fine-tuning had precision values of over 0.80 for "physical" and "work/financial" out of the five concerns. On the other hand, precision for "treatment" was low at approximately 0.25. However, for the classifiers using domain adaptation, the precision of this label took a range of 0.40-0.51, with some cases improving by more than 0.2. This study showed combining domain adaptation with a multi-label classifier on target data made it possible to efficiently extract multiple concerns from interviews., Competing Interests: HY is the CEO of Mediaid Corporation, which operates LifePalette. The other authors declare no competing. This does not alter our adherence to PLOS ONE policies on sharing data and materials., (Copyright: © 2024 Watabe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Recent advances in Natural Language Processing (NLP) have produced state of the art results on several sequence to sequence (seq2seq) tasks. Enhancements in embedders and their training methodologies have shown significant improvement on downstream tasks. Word vector models like Word2Vec, FastText & Glove were widely used over one-hot encoded vectors for years until the advent of deep contextualized embedders. Protein sequences consist of 20 naturally occurring amino acids that can be treated as the language of nature. These amino acids in combinations with each other makeup the biological functions. The choice of vector representation and architecture design for a biological task is highly dependent upon the nature of the task. We utilize unlabelled protein sequences to train a Convolution and Gated Recurrent Network (CGRN) embedder using Masked Language Modeling (MLM) technique that shows significant performance boost under resource constraint setting on two downstream tasks i.e., F1-score(Q8) of 73.1% on Secondary Structure Prediction (SSP) & F1-score of 84% on Intrinsically Disordered Region Prediction (IDRP). We also compare different architectures on downstream tasks to show the impact of the nature of biological task on the performance of the model.

Algorithmic automatic item generation can be used to obtain large quantities of cognitive items in the domains of knowledge and aptitude testing. However, conventional item models used by template-based automatic item generation techniques are not ideal for the creation of items for non-cognitive constructs. Progress in this area has been made recently by employing long short-term memory recurrent neural networks to produce word sequences that syntactically resemble items typically found in personality questionnaires. To date, such items have been produced unconditionally, without the possibility of selectively targeting personality domains. In this article, we offer a brief synopsis on past developments in natural language processing and explain why the automatic generation of construct-specific items has become attainable only due to recent technological progress. We propose that pre-trained causal transformer models can be fine-tuned to achieve this task using implicit parameterization in conjunction with conditional generation. We demonstrate this method in a tutorial-like fashion and finally compare aspects of validity in human- and machine-authored items using empirical data. Our study finds that approximately two-thirds of the automatically generated items show good psychometric properties (factor loadings above .40) and that one-third even have properties equivalent to established and highly curated human-authored items. Our work thus demonstrates the practical use of deep neural networks for non-cognitive automatic item generation., (© 2021. The Author(s).)

Over the past two decades, language modeling (LM) has emerged as a primary methodology for language understanding and generation. This technology has become a cornerstone within the field of natural language processing (NLP). At its core, LM is designed to train models to predict the probability of the next word or token, thereby generating natural and fluent language. The advent of large language models (LLMs), such as Bidirectional Encoder Representations from Transformers and GPT-3, marks a significant milestone in the evolution of LM. These LLMs have left a profound impact on the field of artificial intelligence (AI) while also paving the way for advancements in other domains. This progression underscores the power and efficacy of AI, illustrating how the landscape of AI research has been reshaped by the rapid advancement of LLMs. This paper provides a comprehensive review of the evolution of LLMs, focusing on the technical architecture, model scale, training methods, optimization techniques, and evaluation metrics. Language models have evolved significantly over time, starting from initial statistical language models, moving onto neural network-based models, and now embracing the era of advanced pre-trained language models. As the scale of these models has expanded, so has their performance in language understanding and generation. This has led to notable results across various sectors, including education, healthcare, finance, and industry. However, the application of LLMs also presents certain challenges, such as data quality, model generalization capabilities, and computational resources. This paper delves into these issues, providing an analysis of the strengths and limitations of LLMs. Furthermore, the rise of LLMs has sparked a series of ethical, privacy, and security concerns. For instance, LLMs may generate discriminatory, false, or misleading information, infringe on personal privacy, or even be exploited for malicious activities such as cyber-attacks. To tackle these issues, this paper explores relevant technical measures, such as model interpretability, privacy protection, and security assessments. Ultimately, the paper outlines potential future research trends of LLMs. With ongoing enhancements to model scale and efficiency, LLMs are expected to play an even greater role in multimodal processing and societal impact. For example, by integrating information from different modalities, such as images and sound, LLMs can better understand and generate language. Additionally, they can be employed for societal impact assessment, providing support for policy formulation and decision-making. By thoroughly analyzing the current state of research and potential future directions, this paper aims to offer researchers valuable insights and inspiration regarding LLMs, thereby fostering further advancement in the field.

Detecting plagiarism poses a significant challenge for academic institutions, research centers, and content-centric organizations, especially in cases involving subtle paraphrasing and content manipulation where conventional methods often prove inadequate. Our paper proposes FTLM (Fuzzy TOPSIS Language Modeling), a novel method for detecting plagiarism within decision science. FTLM integrates language models with fuzzy sorting techniques to assess plagiarism severity by evaluating the similarity of potential solutions to a reference. The method involves two stages: leveraging language modeling to define criteria and alternatives and implementing enhanced fuzzy TOPSIS. Word usage patterns, grammatical structures, and semantic coherence represent fuzzy membership functions. Moreover, pre-trained language models enhance semantic similarity analysis. This approach highlights the benefits of combining fuzzy logic’s tolerance for imprecision with the semantic evaluation capabilities of advanced language models, thereby offering a comprehensive and contextually aware method for analyzing plagiarism severity. The experimental results on the benchmark dataset demonstrate effective features that enhance performance on the user-defined severity ranking order.

Purpose: Radiology-pathology correlation has long been foundational to continuing education, peer learning, quality assurance, and multidisciplinary patient care. The objective of this study was to determine whether modern deep-learning language-modeling techniques could reliably match pathology reports to pertinent radiology reports., Methods: The recently proposed Universal Language Model Fine-Tuning for Text Classification methodology was used. Two hundred thousand radiology and pathology reports were used for adaptation to the radiology-pathology space. One hundred thousand candidate radiology-pathology pairs, evenly split into match and no-match categories, were used for training the final binary classification model. Matches were defined by a previous-generation artificial intelligence anatomic concept radiology-pathology correlation system., Results: The language model rapidly adapted very closely to the prior anatomic concept-matching approach, with 100% specificity, 65.1% sensitivity, and 73.7% accuracy. For comparison, the previous methodology, which was intentionally designed to be specific at the expense of sensitivity, had 98.0% specificity, 65.1% sensitivity, and 73.2% accuracy., Conclusions: Modern deep-learning language-modeling approaches are promising for radiology-pathology correlation. Because of their rapid adaptation to underlying training labels, these models advance previous artificial intelligence work in that they can be continuously improved and tuned to improve performance and adjust to user and site-level preference., (Copyright © 2019 American College of Radiology. Published by Elsevier Inc. All rights reserved.)

Abstract Background Longitudinal data on key cancer outcomes for clinical research, such as response to treatment and disease progression, are not captured in standard cancer registry reporting. Manual extraction of such outcomes from unstructured electronic health records is a slow, resource-intensive process. Natural language processing (NLP) methods can accelerate outcome annotation, but they require substantial labeled data. Transfer learning based on language modeling, particularly using the Transformer architecture, has achieved improvements in NLP performance. However, there has been no systematic evaluation of NLP model training strategies on the extraction of cancer outcomes from unstructured text. Results We evaluated the performance of nine NLP models at the two tasks of identifying cancer response and cancer progression within imaging reports at a single academic center among patients with non-small cell lung cancer. We trained the classification models under different conditions, including training sample size, classification architecture, and language model pre-training. The training involved a labeled dataset of 14,218 imaging reports for 1112 patients with lung cancer. A subset of models was based on a pre-trained language model, DFCI-ImagingBERT, created by further pre-training a BERT-based model using an unlabeled dataset of 662,579 reports from 27,483 patients with cancer from our center. A classifier based on our DFCI-ImagingBERT, trained on more than 200 patients, achieved the best results in most experiments; however, these results were marginally better than simpler “bag of words” or convolutional neural network models. Conclusion When developing AI models to extract outcomes from imaging reports for clinical cancer research, if computational resources are plentiful but labeled training data are limited, large language models can be used for zero- or few-shot learning to achieve reasonable performance. When computational resources are more limited but labeled training data are readily available, even simple machine learning architectures can achieve good performance for such tasks.

Objective: In this work we propose a probabilistic graphical model framework that uses language priors at the level of words as a mechanism to increase the performance of P300-based spellers., Approach: This paper is concerned with brain-computer interfaces based on P300 spellers. Motivated by P300 spelling scenarios involving communication based on a limited vocabulary, we propose a probabilistic graphical model framework and an associated classification algorithm that uses learned statistical models of language at the level of words. Exploiting such high-level contextual information helps reduce the error rate of the speller., Main Results: Our experimental results demonstrate that the proposed approach offers several advantages over existing methods. Most importantly, it increases the classification accuracy while reducing the number of times the letters need to be flashed, increasing the communication rate of the system., Significance: The proposed approach models all the variables in the P300 speller in a unified framework and has the capability to correct errors in previous letters in a word, given the data for the current one. The structure of the model we propose allows the use of efficient inference algorithms, which in turn makes it possible to use this approach in real-time applications.

Hundreds of millions of people now interact with language models, with uses ranging from help with writing 1,2 to informing hiring decisions 3 . However, these language models are known to perpetuate systematic racial prejudices, making their judgements biased in problematic ways about groups such as African Americans 4-7 . Although previous research has focused on overt racism in language models, social scientists have argued that racism with a more subtle character has developed over time, particularly in the United States after the civil rights movement 8,9 . It is unknown whether this covert racism manifests in language models. Here, we demonstrate that language models embody covert racism in the form of dialect prejudice, exhibiting raciolinguistic stereotypes about speakers of African American English (AAE) that are more negative than any human stereotypes about African Americans ever experimentally recorded. By contrast, the language models' overt stereotypes about African Americans are more positive. Dialect prejudice has the potential for harmful consequences: language models are more likely to suggest that speakers of AAE be assigned less-prestigious jobs, be convicted of crimes and be sentenced to death. Finally, we show that current practices of alleviating racial bias in language models, such as human preference alignment, exacerbate the discrepancy between covert and overt stereotypes, by superficially obscuring the racism that language models maintain on a deeper level. Our findings have far-reaching implications for the fair and safe use of language technology., (© 2024. The Author(s).)

Large Language Models (LLMs) have ushered in a major paradigm shift in Natural Language Processing (NLP), where large pre-trained Language models (LMs) have become a fundamental component of most NLP tasks. These models are intelligent enough to find relevant and meaningful representations of a language without any supervision. They are used to fine-tune typical NLP tasks with substantially higher precision than conventional shallow learning techniques. However, training these models requires a massively large corpus that adequately represents a language. Due to the availability of enormous corpora, English LLMs typically perform better than their counterparts. This effort focuses on the design and development of a large Arabic corpus. The corpus comprises over 500 GB of Arabic cleaned text, intended to improve cross-domain knowledge and downstream generalization capability of LLMs. The corpus was employed in the training of a large Arabic LLM. In order to assess the efficacy of the LLM, a variety of typical NLP tasks were fine-tuned. The fine-tuned tasks exhibited a significant boost in accuracy ranging between 4.5 and 8.5%, when compared to those downstreamed from multi-lingual BERT (mBERT). To the best of our knowledge, this is currently the largest clean and diverse Arabic corpus ever assembled. [ABSTRACT FROM AUTHOR]

In today’s world, news outlets have changed dramatically; newspapers are obsolete, and radio is no longer in the picture. People look for news online and on social media, such as Twitter and Facebook. Social media contributors share information and trending stories before verifying their truthfulness, thus, spreading rumors. Early identification of rumors from social media has attracted many researchers. However, a relatively smaller number of studies focused on other languages, such as Arabic. In this study, an Arabic rumor detection model is proposed. The model was built using transformer-based deep learning architecture. According to the literature, transformers are neural networks with outstanding performance in natural language processing tasks. Two transformers-based models, AraBERT and MARBERT, were employed, tested, and evaluated using three recently developed Arabic datasets. These models are extensions to the BERT, Bidirectional Encoder Representations from Transformers, a deep learning model that uses transformer architecture to learn the text representations and leverages the attention mechanism. We have also mitigated the challenges introduced by the imbalanced training datasets by employing two sampling techniques. The experimental results of our proposed approaches achieved a maximum accuracy of 0.97. This result demonstrated the effectiveness of the proposed method and outperformed other existing Arabic rumor detection methods.

Purpose: A large share of the information in electronic medical records (EMRs) consists of free-text compositions. From a computational point-of-view, the continuing prevalence of free-text entry is a major hindrance when the goal is to increase automation in EMRs. However, the efforts in developing standards for the structured representation of medical information have not proven to be a panacea. The information space of clinical medicine is very diverse and constantly evolving, making it challenging to develop standards for the domain. This paper reports a study aiming to increase automation in the EMR through the computational understanding of specific class of medical text in English, namely emergency department chief complaints., Methods: We apply domain-specific analytical modeling for the computational understanding of chief complaints. We evaluate the performance of this approach in the automatic classification of chief complaints, e.g., for use in automatic syndromic surveillance., Results: The evaluation in a multi-hospital setting showed that the presented algorithm was accurate in terms of classification correctness. Also, use of approximate matching in the algorithm to cope with typographic variance did not affect classification correctness while increasing classification completeness.

We are developing an automatic captioning system for teleconsultation video teleconferencing (TC-VTC) in telemedicine, based on large vocabulary conversational speech recognition. In TC-VTC, doctors' speech contains a large number of infrequently used medical terms in spontaneous styles. Due to insufficiency of data, we adopted mixture language modeling, with models trained from several datasets of medical and nonmedical domains. This paper proposes novel modeling and estimation methods for the mixture language model (LM). Component LMs are trained from individual datasets, with class n-gram LMs trained from in-domain datasets and word n-gram LMs trained from out-of-domain datasets, and they are interpolated into a mixture LM. For class LMs, semantic categories are used for class definition on medical terms, names, and digits. The interpolation weights of a mixture LM are estimated by a greedy algorithm of forward weight adjustment (FWA). The proposed mixing of in-domain class LMs and out-of-domain word LMs, the semantic definitions of word classes, as well as the weight-estimation algorithm of FWA are effective on the TC-VTC task. As compared with using mixtures of word LMs with weights estimated by the conventional expectation-maximization algorithm, the proposed methods led to a 21% reduction of perplexity on test sets of five doctors, which translated into improvements of captioning accuracy.

The article is an essay on the development of technologies for natural language processing, which formed the basis of BERT (Bidirectional Encoder Representations from Transformers), a language model from Google, showing high results on the whole class of problems associated with the understanding of natural language. Two key ideas implemented in BERT are knowledge transfer and attention mechanism. The model is designed to solve two problems on a large unlabeled data set and can reuse the identified language patterns for effective learning for a specific text processing problem. Architecture Transformer is based on the attention mechanism, i.e. it involves evaluation of relationships between input data tokens. In addition, the article notes strengths and weaknesses of BERT and the directions for further model improvement.

Post marketing safety surveillance depends in part on the ability to detect concerning clinical events at scale. Spontaneous reporting might be an effective component of safety surveillance, but it requires awareness and understanding among healthcare professionals to achieve its potential. Reliance on readily available structured data such as diagnostic codes risks under-coding and imprecision. Clinical textual data might bridge these gaps, and natural language processing (NLP) has been shown to aid in scalable phenotyping across healthcare records in multiple clinical domains. In this study, we developed and validated a novel incident phenotyping approach using unstructured clinical textual data agnostic to Electronic Health Record (EHR) and note type. It's based on a published, validated approach (PheRe) used to ascertain social determinants of health and suicidality across entire healthcare records. To demonstrate generalizability, we validated this approach on two separate phenotypes that share common challenges with respect to accurate ascertainment: (1) suicide attempt; (2) sleep-related behaviors. With samples of 89,428 records and 35,863 records for suicide attempt and sleep-related behaviors, respectively, we conducted silver standard (diagnostic coding) and gold standard (manual chart review) validation. We showed Area Under the Precision-Recall Curve of ~ 0.77 (95% CI 0.75-0.78) for suicide attempt and AUPR ~ 0.31 (95% CI 0.28-0.34) for sleep-related behaviors. We also evaluated performance by coded race and demonstrated differences in performance by race differed across phenotypes. Scalable phenotyping models, like most healthcare AI, require algorithmovigilance and debiasing prior to implementation., (© 2024. The Author(s).)

Probabilistic Bayesian methods are widely used in the machine learning domain. Variational Autoencoder (VAE) is a common architecture for solving the Language Modeling task in a self-supervised way. VAE consists of a concept of latent variables inside the model. Latent variables are described as a random variable that is fit by the data. Up to now, in the majority of cases, latent variables are considered normally distributed. The normal distribution is a well-known distribution that can be easily included in any pipeline. Moreover, the normal distribution is a good choice when the Central Limit Theorem (CLT) holds. It makes it effective when one is working with i.i.d. (independent and identically distributed) random variables. However, the conditions of CLT in Natural Language Processing are not easy to check. So, the choice of distribution family is unclear in the domain. This paper studies the priors selection impact of continuous distributions in the Low-Resource Language Modeling task with VAE. The experiment shows that there is a statistical difference between the different priors in the encoder-decoder architecture. We showed that family distribution hyperparameter is important in the Low-Resource Language Modeling task and should be considered for the model training. [ABSTRACT FROM AUTHOR]

Personality Traits Detection is one of the important problems as a text analytics task in Natural Language Processing (NLP). Text analytics is the process of finding out insight knowledge over written text. Although most deep learning models give high performance, they often lack interpretability. Computer Vision (CV) has been affected significantly with inductive transfer learning, however training from scratch and task-specific modifications are still wanted in many NLP techniques. This paper addresses the problem of personality traits classification. We adopted the use of the Universal Language Model Fine-Tuning (ULMFiT) in personality traits detection. The model makes use of transfer learning rather than the classical shallow methods of word embedding and proved to be the most powerful model in many NLP problems. The basic advantage of using this model is that there is no need to do feature engineering before classification. When applied to benchmark dataset, the proposed method shows a statistical accuracy improvement of about 1% compared to the state-of-the-art results for the big five personality traits. [ABSTRACT FROM AUTHOR]

Background: Clinical narratives are essential components of electronic health records. The adoption of electronic health records has increased documentation time for hospital staff, leading to the use of abbreviations and acronyms more frequently. This brevity can potentially hinder comprehension for both professionals and patients., Objective: This review aims to provide an overview of the types of short forms found in clinical narratives, as well as the natural language processing (NLP) techniques used for their identification, expansion, and disambiguation., Methods: In the databases Web of Science, Embase, MEDLINE, EBMR (Evidence-Based Medicine Reviews), and ACL Anthology, publications that met the inclusion criteria were searched according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines for a systematic scoping review. Original, peer-reviewed publications focusing on short-form processing in human clinical narratives were included, covering the period from January 2018 to February 2023. Short-form types were extracted, and multidimensional research methodologies were assigned to each target objective (identification, expansion, and disambiguation). NLP study recommendations and study characteristics were systematically assigned occurrence rates for evaluation., Results: Out of a total of 6639 records, only 19 articles were included in the final analysis. Rule-based approaches were predominantly used for identifying short forms, while string similarity and vector representations were applied for expansion. Embeddings and deep learning approaches were used for disambiguation., Conclusions: The scope and types of what constitutes a clinical short form were often not explicitly defined by the authors. This lack of definition poses challenges for reproducibility and for determining whether specific methodologies are suitable for different types of short forms. Analysis of a subset of NLP recommendations for assessing quality and reproducibility revealed only partial adherence to these recommendations. Single-character abbreviations were underrepresented in studies on clinical narrative processing, as were investigations in languages other than English. Future research should focus on these 2 areas, and each paper should include descriptions of the types of content analyzed., (©Amila Kugic, Ingrid Martin, Luise Modersohn, Peter Pallaoro, Markus Kreuzthaler, Stefan Schulz, Martin Boeker. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 26.09.2024.)

Large language models have been shown to achieve remarkable performance across a variety of natural language tasks using few-shot learning, which drastically reduces the number of task-specific training examples needed to adapt the model to a particular application. To further our understanding of the impact of scale on few-shot learning, we trained a 540-billion parameter, densely activated, Transformer language model, which we call Pathways Language Model (PaLM). We trained PaLM on 6144 TPU v4 chips using Pathways, a new ML system which enables highly efficient training across multiple TPU Pods. We demonstrate continued benefits of scaling by achieving state-of-the-art few-shot learning results on hundreds of language understanding and generation benchmarks. On a number of these tasks, PaLM 540B achieves breakthrough performance, outperforming the fine-tuned state-of-the-art on a suite of multi-step reasoning tasks, and outperforming average human performance on the recently released BIG-bench benchmark. A significant number of BIG-bench tasks showed discontinuous improvements from model scale, meaning that performance steeply increased as we scaled to our largest model. PaLM also has strong capabilities in multilingual tasks and source code generation, which we demonstrate on a wide array of benchmarks. We additionally provide a comprehensive analysis on bias and toxicity, and study the extent of training data memorization with respect to model scale. Finally, we discuss the ethical considerations related to large language models and discuss potential mitigation strategies. [ABSTRACT FROM AUTHOR]

• We compare and map the semantic spaces of sensory vocabularies of wine, perfume, and food reviews. • Vocabularies differ with respect to domain specificity, concreteness, descriptor type preference and degree of gustatory vs. olfactory association. • Wine vocabulary distinguishes between white and red wine qualities. Food vocabulary drinkables and edibles, as well as savory and non-savory products. • All vocabularies distinguish descriptors in terms of concreteness and valence, but valence is less prominent than in general olfactory vocabulary. • Our novel method allows a systematic comparison of sensory domains and provides a data-driven approach to derive domain-specific sensory lexicons. Chemosensory sensations are often hard to describe and quantify. Language models may facilitate a systematic understanding of sensory descriptions. We accessed consumer and expert reviews of wine, perfume, and food products (English language; about 68 million words in total) and analyzed their sensory descriptions. Using a novel data-driven method based on natural language data, we compared the three chemosensory vocabularies (wine, perfume, food) with respect to their vocabulary overlap and semantic properties, and explored their semantic spaces. The three vocabularies primarily differ with respect to domain specificity, concreteness, descriptor type preference and degree of gustatory vs. olfactory association. Wine vocabulary primarily distinguishes between white wine and red wine flavors and qualities. Food vocabulary separates drinkable and edible food products and ingredients, on the one hand, and savory and non-savory products, on the other. A salient distinction in all three vocabularies is between concrete and abstract/evaluative terms. Valence also plays a role in the semantic spaces of all three vocabularies, but valence is less prominent here than in general olfactory vocabulary. Our method allows a systematic comparison of sensory descriptors in the three product domains and provides a data-driven approach to derive sensory lexicons that can be applied by sensory scientists. [ABSTRACT FROM AUTHOR]

Here we represent human lives in a way that shares structural similarity to language, and we exploit this similarity to adapt natural language processing techniques to examine the evolution and predictability of human lives based on detailed event sequences. We do this by drawing on a comprehensive registry dataset, which is available for Denmark across several years, and that includes information about life-events related to health, education, occupation, income, address and working hours, recorded with day-to-day resolution. We create embeddings of life-events in a single vector space, showing that this embedding space is robust and highly structured. Our models allow us to predict diverse outcomes ranging from early mortality to personality nuances, outperforming state-of-the-art models by a wide margin. Using methods for interpreting deep learning models, we probe the algorithm to understand the factors that enable our predictions. Our framework allows researchers to discover potential mechanisms that impact life outcomes as well as the associated possibilities for personalized interventions., (© 2023. The Author(s), under exclusive licence to Springer Nature America, Inc.)

Proving mathematical theorems at the olympiad level represents a notable milestone in human-level automated reasoning 1-4 , owing to their reputed difficulty among the world's best talents in pre-university mathematics. Current machine-learning approaches, however, are not applicable to most mathematical domains owing to the high cost of translating human proofs into machine-verifiable format. The problem is even worse for geometry because of its unique translation challenges 1,5 , resulting in severe scarcity of training data. We propose AlphaGeometry, a theorem prover for Euclidean plane geometry that sidesteps the need for human demonstrations by synthesizing millions of theorems and proofs across different levels of complexity. AlphaGeometry is a neuro-symbolic system that uses a neural language model, trained from scratch on our large-scale synthetic data, to guide a symbolic deduction engine through infinite branching points in challenging problems. On a test set of 30 latest olympiad-level problems, AlphaGeometry solves 25, outperforming the previous best method that only solves ten problems and approaching the performance of an average International Mathematical Olympiad (IMO) gold medallist. Notably, AlphaGeometry produces human-readable proofs, solves all geometry problems in the IMO 2000 and 2015 under human expert evaluation and discovers a generalized version of a translated IMO theorem in 2004., (© 2024. The Author(s).)

In the contemporary digital age, social media platforms like Facebook, Twitter, and YouTube serve as vital channels for individuals to express ideas and connect with others. Despite fostering increased connectivity, these platforms have inadvertently given rise to negative behaviors, particularly cyberbullying. While extensive research has been conducted on high-resource languages such as English, there is a notable scarcity of resources for low-resource languages like Bengali, Arabic, Tamil, etc., particularly in terms of language modeling. This study addresses this gap by developing a cyberbullying text identification system called BullyFilterNeT tailored for social media texts, considering Bengali as a test case. The intelligent BullyFilterNeT system devised overcomes Out-of-Vocabulary (OOV) challenges associated with non-contextual embeddings and addresses the limitations of context-aware feature representations. To facilitate a comprehensive understanding, three non-contextual embedding models GloVe, FastText, and Word2Vec are developed for feature extraction in Bengali. These embedding models are utilized in the classification models, employing three statistical models (SVM, SGD, Libsvm), and four deep learning models (CNN, VDCNN, LSTM, GRU). Additionally, the study employs six transformer-based language models: mBERT, bELECTRA, IndicBERT, XML-RoBERTa, DistilBERT, and BanglaBERT, respectively to overcome the limitations of earlier models. Remarkably, BanglaBERT-based BullyFilterNeT achieves the highest accuracy of 88.04% in our test set, underscoring its effectiveness in cyberbullying text identification in the Bengali language. [ABSTRACT FROM AUTHOR]

Initial results of neural architecture search (NAS) in natural language processing (NLP) have been achieved, but the search space of most NAS methods is based on the simplest recurrent cell and thus does not consider the modeling of long sequences. The remote information tends to disappear gradually when the input sequence is long, resulting in poor model performance. In this paper, we present an approach based on dual cells to search for a better-performing network architecture. We construct a search space that is more compatible with language modeling tasks by adding an information storage cell inside the search cell, so that we can make better use of the remote information of the sequence and improve the performance of the model. The language model searched by our method achieves better results than those of the baseline method on the Penn Treebank data set and WikiText-2 data set. [ABSTRACT FROM AUTHOR]

Background and Objectives: Clinical registries are critical for modern surgery and underpin outcomes research, device monitoring, and trial development. However, existing approaches to registry construction are labor-intensive, costly, and prone to manual error. Natural language processing techniques combined with electronic health record (EHR) data sets can theoretically automate the construction and maintenance of registries. Our aim was to automate the generation of a spine surgery registry at an academic medical center using regular expression (regex) classifiers developed by neurosurgeons to combine domain expertise with interpretable algorithms., Methods: We used a Hadoop data lake consisting of all the information generated by an academic medical center. Using this database and structured query language queries, we retrieved every operative note written in the department of neurosurgery since our transition to EHR. Notes were parsed using regex classifiers and compared with a random subset of 100 manually reviewed notes., Results: A total of 31 502 operative cases were downloaded and processed using regex classifiers. The codebase required 5 days of development, 3 weeks of validation, and less than 1 hour for the software to generate the autoregistry. Regex classifiers had an average accuracy of 98.86% at identifying both spinal procedures and the relevant vertebral levels, and it correctly identified the entire list of defined surgical procedures in 89% of patients. We were able to identify patients who required additional operations within 30 days to monitor outcomes and quality metrics., Conclusion: This study demonstrates the feasibility of automatically generating a spine registry using the EHR and an interpretable, customizable natural language processing algorithm which may reduce pitfalls associated with manual registry development and facilitate rapid clinical research., (Copyright © Congress of Neurological Surgeons 2023. All rights reserved.)

As dialogue agents become increasingly human-like in their performance, we must develop effective ways to describe their behaviour in high-level terms without falling into the trap of anthropomorphism. Here we foreground the concept of role play. Casting dialogue-agent behaviour in terms of role play allows us to draw on familiar folk psychological terms, without ascribing human characteristics to language models that they in fact lack. Two important cases of dialogue-agent behaviour are addressed this way, namely, (apparent) deception and (apparent) self-awareness., (© 2023. Springer Nature Limited.)