17 results on '"Penner, Reginald M."'
Search Results
2. Electrically Transduced Sensors Based on Nanomaterials (2012-2016).
- Author
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Chandran GT, Li X, Ogata A, and Penner RM
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- Animals, Carbon chemistry, Humans, Polymers chemistry, Electricity, Nanostructures, Nanotechnology instrumentation
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- 2017
- Full Text
- View/download PDF
3. A year for nanoscience.
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Chan WC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Khademhosseini A, Kotov NA, Lee ST, Möhwald H, Mulvaney PA, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Willson CG, and Weiss PS
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- Nanotechnology, Periodicals as Topic, Science
- Published
- 2014
- Full Text
- View/download PDF
4. Wafer-scale fabrication of nanofluidic arrays and networks using nanoimprint lithography and lithographically patterned nanowire electrodeposition gold nanowire masters.
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Halpern AR, Donavan KC, Penner RM, and Corn RM
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- Dimethylpolysiloxanes chemistry, Electroplating, Microscopy, Atomic Force, Microscopy, Electron, Scanning, Nanowires ultrastructure, Printing, Silicon Dioxide chemistry, Surface Properties, Gold chemistry, Nanotechnology methods, Nanowires chemistry
- Abstract
Wafer scale (cm(2)) arrays and networks of nanochannels were created in polydimethylsiloxane (PDMS) from a surface pattern of electrodeposited gold nanowires in a master-replica process and characterized with scanning electron microscopy (SEM), atomic force microscopy (AFM), and fluorescence imaging measurements. Patterns of gold nanowires with cross-sectional dimensions as small as 50 nm in height and 100 nm in width were prepared on silica substrates using the process of lithographically patterned nanowire electrodeposition (LPNE). These nanowire patterns were then employed as masters for the fabrication of inverse replica nanochannels in a special formulation of PDMS. SEM and AFM measurements verified a linear correlation between the widths and heights of the nanowires and nanochannels over a range of 50 to 500 nm. The PDMS replica was then oxygen plasma-bonded to a glass substrate in order to create a linear array of nanofluidic channels (up to 1 mm in length) filled with solutions of either fluorescent dye or 20 nm diameter fluorescent polymer nanoparticles. Nanochannel continuity and a 99% fill success rate was determined from the fluorescence imaging measurements, and the electrophoretic injection of both dye and nanoparticles in the nanochannel arrays was also demonstrated. Employing a double LPNE fabrication method, this master-replica process was also used to create a large two-dimensional network of crossed nanofluidic channels.
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- 2012
- Full Text
- View/download PDF
5. Joule heating a palladium nanowire sensor for accelerated response and recovery to hydrogen gas.
- Author
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Yang F, Taggart DK, and Penner RM
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- Adsorption, Electric Impedance, Temperature, Time Factors, Heating, Hydrogen analysis, Nanotechnology instrumentation, Nanowires chemistry, Palladium chemistry
- Abstract
The properties of a single heated palladium (Pd) nanowire for the detection of hydrogen gas (H(2)) are explored. In these experiments, a Pd nanowire, 48-98 microm in length, performs three functions in parallel: 1) Joule self-heating is used to elevate the nanowire temperature by up to 128 K, 2) the 4-contact wire resistance in the absence of H(2) is used to measure its temperature, and 3) the nanowire resistance in the presence of H(2) is correlated with its concentration, allowing it to function as a H(2) sensor. Compared with the room-temperature response of a Pd nanowire, the response of the heated nanowire to hydrogen is altered in two ways: First, the resistance change (DeltaR/R(0)) induced by H(2) exposure at any concentration is reduced by a factor of up to 30 and second, the rate of the resistance change - observed at the beginning ("response") and at the end ("recovery") of a pulse of H(2) - is increased by more than a factor of 50 at some H(2) concentrations. Heating nearly eliminates the retardation of response and recovery seen from 1-2% H(2), caused by the alpha --> beta phase transition of PdH(x), a pronounced effect for nanowires at room temperature. The activation energies associated with sensor response and recovery are measured and interpreted.
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- 2010
- Full Text
- View/download PDF
6. 20 micros photocurrent response from lithographically patterned nanocrystalline cadmium selenide nanowires.
- Author
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Kung SC, van der Veer WE, Yang F, Donavan KC, and Penner RM
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- Electrochemistry, Electrodes, Gold chemistry, Light, Particle Size, Photochemistry, Surface Properties, Cadmium Compounds chemistry, Nanotechnology methods, Nanowires chemistry, Selenium Compounds chemistry
- Abstract
Lithographically patterned nanowire electrodeposition (LPNE) provides a method for patterning nanowires composed of nanocrystalline cadmium selenide (nc-CdSe) over wafer-scale areas. We assess the properties of (nc-CdSe) nanowires for detecting light as photoconductors. Structural characterization of these nanowires by X-ray diffraction and transmission electron microscopy reveals they are composed of stoichiometric, single phase, cubic CdSe with a mean grain diameter of 10 nm. For nc-CdSe nanowires with lengths of many millimeters, the width and height dimensions could be varied over the range from 60 to 350 nm (w) and 20 to 80 nm (h). Optical absorption and photoluminescence spectra for nc-CdSe nanowires were both dominated by band-edge transitions. The photoconductivity properties of nc-CdSe nanowire arrays containing approximately 350 nanowires were evaluated by electrically isolating 5 microm nanowire lengths using evaporated gold electrodes. Photocurrents, i(photo), of 10-100 x (i(dark)) were observed with a spectral response characterized by an onset at 1.75 eV. i(photo) response and recovery times were virtually identical and in the range from 20 to 40 micros for 60 x 200 nm nanowires.
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- 2010
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- View/download PDF
7. Wafer-scale patterning of lead telluride nanowires: structure, characterization, and electrical properties.
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Yang Y, Taggart DK, Brown MA, Xiang C, Kung SC, Yang F, Hemminger JC, and Penner RM
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- Electric Conductivity, Macromolecular Substances chemistry, Materials Testing, Molecular Conformation, Nanotubes chemistry, Particle Size, Surface Properties, Crystallization methods, Lead chemistry, Nanotechnology methods, Nanotubes ultrastructure, Tellurium chemistry, Titanium chemistry
- Abstract
Nanowires of lead telluride (PbTe) were patterned on glass surfaces using lithographically patterned nanowire electrodeposition (LPNE). LPNE involved the fabrication by photolithography of a contoured nickel nanoband that is recessed by approximately 300 nm into a horizontal photoresist trench. Cubic PbTe was then electrodeposited from a basic aqueous solution containing Pb(2+) and TeO(3)(2-) at the nickel nanoband using a cyclic deposition/stripping potential program in which lead-rich PbTe was first deposited in a negative-going potential scan and excess lead was then anodically stripped from the nascent nanowire by scanning in the positive direction to produce near stoichiometric PbTe. Repeating this scanning procedure permitted PbTe nanowires 60-400 nm in width to be obtained. The wire height was controlled over the range of 20-100 nm based upon the nickel film thickness. Nanowires with lengths exceeding 1 cm were prepared in this study. We report the characterization of these nanowires using X-ray diffraction, transmission electron microscopy and electron diffraction, scanning electron microscopy, and X-ray photoelectron spectroscopy (XPS). The surface chemical composition of PbTe nanowires was monitored by XPS as a function of time during the exposure of these nanowires to laboratory air. One to two monolayers of a mixed Pb and Te oxide are formed during a 24 h exposure. The electrical conductivity of PbTe nanowires was strongly affected by air oxidation, declining from an initial value of 2.0(+/-1.5) x 10 (4) S/m by 61% (for nanowires with a 20 nm thickness), 55% (for 40 nm), and 12% (for 60 nm).
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- 2009
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8. Lithographically patterned nanowire electrodeposition: a method for patterning electrically continuous metal nanowires on dielectrics.
- Author
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Xiang C, Kung SC, Taggart DK, Yang F, Thompson MA, Güell AG, Yang Y, and Penner RM
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- Electric Conductivity, Macromolecular Substances chemistry, Materials Testing, Molecular Conformation, Particle Size, Surface Properties, Crystallization methods, Electroplating methods, Gold chemistry, Nanostructures chemistry, Nanostructures ultrastructure, Nanotechnology methods, Nickel chemistry
- Abstract
Lithographically patterned nanowire electrodeposition (LPNE) is a new method for fabricating polycrystalline metal nanowires using electrodeposition. In LPNE, a sacrificial metal (M(1)=silver or nickel) layer, 5-100 nm in thickness, is first vapor deposited onto a glass, oxidized silicon, or Kapton polymer film. A (+) photoresist (PR) layer is then deposited, photopatterned, and the exposed Ag or Ni is removed by wet etching. The etching duration is adjusted to produce an undercut approximately 300 nm in width at the edges of the exposed PR. This undercut produces a horizontal trench with a precisely defined height equal to the thickness of the M(1) layer. Within this trench, a nanowire of metal M(2) is electrodeposited (M(2)=gold, platinum, palladium, or bismuth). Finally the PR layer and M(1) layer are removed. The nanowire height and width can be independently controlled down to minimum dimensions of 5 nm (h) and 11 nm (w), for example, in the case of platinum. These nanowires can be 1 cm in total length. We measure the temperature-dependent resistance of 100 microm sections of Au and Pd wires in order to estimate an electrical grain size for comparison with measurements by X-ray diffraction and transmission electron microscopy. Nanowire arrays can be postpatterned to produce two-dimensional arrays of nanorods. Nanowire patterns can also be overlaid one on top of another by repeating the LPNE process twice in succession to produce, for example, arrays of low-impedance, nanowire-nanowire junctions.
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- 2008
- Full Text
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9. Investigation of a single Pd nanowire for use as a hydrogen sensor.
- Author
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Im Y, Lee C, Vasquez RP, Bangar MA, Myung NV, Menke EJ, Penner RM, and Yun M
- Subjects
- Biosensing Techniques methods, Electric Conductivity, Electric Wiring, Electrochemistry methods, Equipment Design, Equipment Failure Analysis, Hydrogen chemistry, Materials Testing, Molecular Conformation, Nanostructures ultrastructure, Nanotechnology methods, Particle Size, Surface Properties, Biosensing Techniques instrumentation, Crystallization methods, Electrochemistry instrumentation, Hydrogen analysis, Nanostructures chemistry, Nanotechnology instrumentation, Palladium chemistry
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- 2006
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10. Moving Electrons Purposefully through Single Molecules and Nanostructures: A Tribute to the Science of Professor Nongjian Tao (1963–2020)
- Author
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Forzani, Erica S, He, Huixin, Hihath, Joshua, Lindsay, Stuart, Penner, Reginald M, Wang, Shaopeng, and Xu, Bingqian
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Electrochemistry ,Electrons ,Humans ,Nanostructures ,Nanotechnology ,Nanoscience & Nanotechnology - Abstract
Electrochemistry intersected nanoscience 25 years ago when it became possible to control the flow of electrons through single molecules and nanostructures. Many surprises and a wealth of understanding were generated by these experiments. Professor Nongjian Tao was among the pioneering scientists who created the methods and technologies for advancing this new frontier. Achieving a deeper understanding of charge transport in molecules and low-dimensional materials was the first priority of his experiments, but he also succeeded in discovering applications in chemical sensing and biosensing for these novel nanoscopic systems. In parallel with this work, the investigation of a range of phenomena using novel optical microscopic methods was a passion of his and his students. This article is a review and an appreciation of some of his many contributions with a view to the future.
- Published
- 2020
11. Diverse Applications of Nanomedicine.
- Author
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Pelaz, Beatriz, Alexiou, Christoph, Alvarez-Puebla, Ramon A, Alves, Frauke, Andrews, Anne M, Ashraf, Sumaira, Balogh, Lajos P, Ballerini, Laura, Bestetti, Alessandra, Brendel, Cornelia, Bosi, Susanna, Carril, Monica, Chan, Warren CW, Chen, Chunying, Chen, Xiaodong, Chen, Xiaoyuan, Cheng, Zhen, Cui, Daxiang, Du, Jianzhong, Dullin, Christian, Escudero, Alberto, Feliu, Neus, Gao, Mingyuan, George, Michael, Gogotsi, Yury, Grünweller, Arnold, Gu, Zhongwei, Halas, Naomi J, Hampp, Norbert, Hartmann, Roland K, Hersam, Mark C, Hunziker, Patrick, Jian, Ji, Jiang, Xingyu, Jungebluth, Philipp, Kadhiresan, Pranav, Kataoka, Kazunori, Khademhosseini, Ali, Kopeček, Jindřich, Kotov, Nicholas A, Krug, Harald F, Lee, Dong Soo, Lehr, Claus-Michael, Leong, Kam W, Liang, Xing-Jie, Ling Lim, Mei, Liz-Marzán, Luis M, Ma, Xiaowei, Macchiarini, Paolo, Meng, Huan, Möhwald, Helmuth, Mulvaney, Paul, Nel, Andre E, Nie, Shuming, Nordlander, Peter, Okano, Teruo, Oliveira, Jose, Park, Tai Hyun, Penner, Reginald M, Prato, Maurizio, Puntes, Victor, Rotello, Vincent M, Samarakoon, Amila, Schaak, Raymond E, Shen, Youqing, Sjöqvist, Sebastian, Skirtach, Andre G, Soliman, Mahmoud G, Stevens, Molly M, Sung, Hsing-Wen, Tang, Ben Zhong, Tietze, Rainer, Udugama, Buddhisha N, VanEpps, J Scott, Weil, Tanja, Weiss, Paul S, Willner, Itamar, Wu, Yuzhou, Yang, Lily, Yue, Zhao, Zhang, Qian, Zhang, Qiang, Zhang, Xian-En, Zhao, Yuliang, Zhou, Xin, and Parak, Wolfgang J
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Animals ,Humans ,Neoplasms ,Drug Carriers ,Drug Delivery Systems ,Particle Size ,Nanotechnology ,Nanomedicine ,Nanoparticles ,Bioengineering ,Prevention ,Biotechnology ,5.1 Pharmaceuticals ,Generic Health Relevance ,Nanoscience & Nanotechnology - Abstract
The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these developments are starting to be translated into viable clinical products. Here, we provide an overview of recent developments in nanomedicine and highlight the current challenges and upcoming opportunities for the field and translation to the clinic.
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- 2017
12. Nano Day: Celebrating the Next Decade of Nanoscience and Nanotechnology.
- Author
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Kagan, Cherie R, Fernandez, Laura E, Gogotsi, Yury, Hammond, Paula T, Hersam, Mark C, Nel, André E, Penner, Reginald M, Willson, C Grant, and Weiss, Paul S
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Nanotechnology ,Bioengineering ,Nanoscience & Nanotechnology - Abstract
Nanoscience and nanotechnology are poised to contribute to a wide range of fields, from health and medicine to electronics, energy, security, and more. These contributions come both directly in the form of new materials, interfaces, tools, and even properties as well as indirectly by connecting fields together. We celebrate how far we have come, and here, we look at what is to come over the next decade that will leverage the strong and growing base that we have built in nanoscience and nanotechnology.
- Published
- 2016
13. Moving Electrons Purposefully through Single Molecules and Nanostructures: A Tribute to the Science of Nongjian Tao
- Author
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Forzani, Erica S., He, Huixin, Hihath, Josh, Lindsay, Stuart, Penner, Reginald M., Wang, Shaopeng, and Xu, Bingqian
- Subjects
Electrochemistry ,Humans ,Nanotechnology ,Electrons ,Article ,Nanostructures - Abstract
Electrochemistry intersected nanoscience 25 years ago when it became possible to control the flow of electrons through single molecules and nanostructures. Many surprises and a wealth of understanding were generated by these experiments. Professor Nongjian Tao was among the pioneering scientists who created the methods and technologies for advancing this new frontier. Achieving a deeper understanding of charge transport in molecules and low-dimensional materials was the first priority of his experiments, but he also succeeded in discovering applications in chemical sensing and biosensing for these novel nanoscopic systems. In parallel with this work, the investigation of a range of phenomena using novel optical microscopic methods was a passion of his and his students. This article is a review and an appreciation of some of his many contributions with a view to the future.
- Published
- 2020
14. Virus-Polymer Hybrid Nanowires Tailored to Detect Prostate-Specific Membrane Antigen.
- Author
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Arter, Jessica A., Diaz, Juan E., Donavan, Keith C., Yuan, Tom, Penner, Reginald M., and Weiss, Gregory A.
- Subjects
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BIOSENSORS , *MACHINE design , *PROSTATE-specific membrane antigen , *SYNTHESIS of nanowires , *MICROFABRICATION , *ELECTROPLATING , *NANOTECHNOLOGY , *VIRION - Abstract
We demonstrate the de novo fabrication of a biosensor, based upon virus-containing poly(3,4-ethylene-dioxythiophene) (PEDOT) nanowires, that detects prostate-specific membrane antigen (PSMA). This development process occurs in three phases: (1) isolation of a M13 virus with a displayed polypeptide receptor, from a library of ≈1011 phage-displayed peptides, which binds PSMA with high affinity and selectivity, (2) microfabrication of PEDOT nanowires that entrain these virus particles using the lithographically patterned nanowire electrodeposition (LPNE) method, and (3) electrical detection of the PSMA in high ionic strength (150 mM salt) media, including synthetic urine, using an array of virus-PEDOT nanowires with the electrical resistance of these nanowires for transduction. The electrical resistance of an array of these nanowires increases linearly with the PSMA concentration from 20 to 120 nM in high ionic strength phosphate-buffered fluoride (PBF) buffer, yielding a limit of detection (LOD) for PSMA of 56 nM. [ABSTRACT FROM AUTHOR]
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- 2012
- Full Text
- View/download PDF
15. Fabricating Nanoscale DNA Patterns with Gold Nanowires.
- Author
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Yulin Chen, Sheng-Chin Kung, Taggart, David K., Halpern, Aaron R., Penner, Reginald M., and Corn, Robert M.
- Subjects
- *
NANOTECHNOLOGY , *NANOPARTICLES , *NANOWIRES , *DNA , *ATOMIC force microscopy , *FLUORESCENCE - Abstract
Surface patterns of single-stranded DNA (ssDNA) consisting of nanoscale lines as thin as 40 nan were fabricated on polymer substrates for nanotechnology and bioaffinity sensing applications. Iarge scale arrays (with areas up to 4 cm2) of ssDNA "nanolines" were created on streptavidin-coated polymer (PDMS) surfaces by transferring biotinylated ssDNA from a master pattern of gold nanowires attached to a glass substrate. The gold nanowires were first formed on the glass substrate by the process of lithographically patterned nanowire electrodeposition (LPNE), and then "inked" with biotinylated ssDNA by hybridization adsorption to a thiolmodified ssDNA monolayer attached to the gold nanowires. The transferred ssDNA nanolines were capable of hybridizing with ssDNA from solution to form double-stranded DNA (dsDNA) patterns; a combination of fluorescence and atomic force microscopy (AFM) measurements were used to characterize the dsDNA nanoline arrays. To demonstrate the utility of these surices for biosensing, optical diffraction measurements of the hybridization adsorption of DNA-coated gold nanoparticles onto the ssDNA nanoline arrays were used to detect a specific target sequence of unlabeled ssDNA in solution. [ABSTRACT FROM AUTHOR]
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- 2010
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16. Nanoscience and Nanotechnology Cross Borders
- Author
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Yury Gogotsi, Jeffrey Brinker, Takhee Lee, Manishkumar Chhowalla, C. N.R. Rao, Darrell J. Irvine, Wolfgang J. Parak, Ali Khademhosseini, Paula T. Hammond, Xing-Jie Liang, Emily A. Weiss, Warren W.C. Chan, Jill E. Millstone, Andre E. Nel, Molly M. Stevens, Christoph Gerber, Andrey L. Rogach, Graham J. Leggett, Yan Li, David S. Ginger, Maurizio Prato, Kostas Kostarelos, Cherie R. Kagan, Raymond E. Schaak, Andrew T. S. Wee, Sharon C. Glotzer, Luis M. Liz-Marzán, Nicholas A. Kotov, Laura L. Kiessling, Paul S. Weiss, Teri W. Odom, Reginald M. Penner, Michael F. Crommie, Xiaoyuan Chen, Omid C. Farokhzad, Christy Landes, Paul Mulvaney, Cees Dekker, Ali Javey, Michael J. Sailor, Shuit-Tong Lee, Mark C. Hersam, Lifeng Chi, Helmuth Möhwald, Aydogan Ozcan, Jason H. Hafner, Khademhosseini, Ali, Chan, Warren W. C., Chhowalla, Manish, Glotzer, Sharon C., Gogotsi, Yury, Hafner, Jason H., Hammond, Paula T., Hersam, Mark C., Javey, Ali, Kagan, Cherie R., Kotov, Nicholas A., Lee, Shuit Tong, Li, Yan, Möhwald, Helmuth, Mulvaney, Paul A., Nel, Andre E., Parak, Wolfgang J., Penner, Reginald M., Rogach, Andrey L., Schaak, Raymond E., Stevens, Molly M., Wee, Andrew T. S., Brinker, Jeffrey, Chen, Xiaoyuan, Chi, Lifeng, Crommie, Michael, Dekker, Cee, Farokhzad, Omid, Gerber, Christoph, Ginger, David S., Irvine, Darrell J., Kiessling, Laura L., Kostarelos, Kosta, Landes, Christy, Lee, Takhee, Leggett, Graham J., Liang, Xing Jie, Liz Marzán, Lui, Millstone, Jill, Odom, Teri W., Ozcan, Aydogan, Prato, Maurizio, Rao, C. N. R., Sailor, Michael J., Weiss, Emily, and Weiss, Paul S.
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Materials science ,Andrey ,Materials Science (all) ,Engineering (all) ,Physics and Astronomy (all) ,General Engineering ,General Physics and Astronomy ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,General Materials Science ,Nanoscience & Nanotechnology ,0210 nano-technology - Abstract
The recent ExecutiveOrder by President Trump attempting to ban temporarily the citizens of seven countries (Iran, Iraq, Libya, Somalia, Sudan, Syria, and Yemen) from entering the United States is having significant consequences within the country and around the world. The Order poses a threat to the health and vitality of science, barring students and scientists from these countries from traveling to the United States to study or to attend conferences. In preventing those members of the international scientific community from traveling beyond U.S. borders without guaranteed safe return, the Executive Order demeans them; in so doing, it demeans us all. Universities and research communities are especially impacted, as major universities have students and often faculty holding passports from one of these seven countries. This temporary ban would affect refugees fleeing war-torn areas, challenging the long-standing notion that the United States is a safe haven for those fleeing persecution and war in addition to being a magnet for talent from every corner of the world. The pages of this journal reflect the geographic, ethnic, and cultural diversity that underpins great science. The ban impacts domestic and global scientific efforts and communities. Science succeeds through the cooperation between collections of individuals and teams around the world discovering and learning from each other. To ensure rapid scientific progress, open communication and exchange between scientists are essential. As scientists, engineers, and clinicians, we have benefited from open interactions and collaborations with visitors and students from all parts of the world as well as through scientific publications and discussions at scientific meetings.
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- 2017
17. Diverse applications of nanomedicine
- Author
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Philipp Jungebluth, Ali Khademhosseini, Xian-En Zhang, Yuzhou Wu, Tai Hyun Park, Christian Dullin, Helmuth Möhwald, Neus Feliu, Mahmoud Soliman, Michael D. George, Nicholas A. Kotov, Buddhisha Udugama, Paul Mulvaney, Ramon A. Alvarez-Puebla, Warren C. W. Chan, Kazunori Kataoka, Sumaira Ashraf, Beatriz Pelaz, Xingyu Jiang, Yury Gogotsi, Naomi J. Halas, Yuliang Zhao, Arnold Grünweller, Laura Ballerini, Jose Oliveira, Ben Zhong Tang, Sebastian Sjöqvist, Susanna Bosi, Andre G. Skirtach, Anne M. Andrews, Teruo Okano, Daxiang Cui, Shuming Nie, Maurizio Prato, Qian Zhang, Patrick Hunziker, Alberto Escudero, Xin Zhou, Qiang Zhang, Huan Meng, Claus-Michael Lehr, Christoph Alexiou, Youqing Shen, Wolfgang J. Parak, Luis M. Liz-Marzán, Lajos P. Balogh, Ji Jian, Andre E. Nel, Molly M. Stevens, Xiaowei Ma, Paul S. Weiss, Zhao Yue, Rainer Tietze, Xiaodong Chen, Raymond E. Schaak, Zhongwei Gu, Chunying Chen, Hsing-Wen Sung, Jindřich Kopeček, Xing-Jie Liang, Alessandra Bestetti, Lily Yang, Harald F. Krug, Paolo Macchiarini, Mei Ling Lim, Vincent M. Rotello, Mónica Carril, Tanja Weil, Zhen Cheng, Pranav Kadhiresan, J. Scott VanEpps, Roland K. Hartmann, Mark C. Hersam, Xiaoyuan Chen, Itamar Willner, Mingyuan Gao, Dong Soo Lee, Amila Samarakoon, Peter Nordlander, Norbert Hampp, Víctor F. Puntes, Cornelia Brendel, Reginald M. Penner, Kam W. Leong, Jianzhong Du, Frauke Alves, Helmholtz-Institute for Pharmaceutical Research Saarland (HIPS),Saarland 9 University, 66123 Saarbrücken, Germany., Pelaz, Beatriz, Alexiou, Christoph, Alvarez Puebla, Ramon A., Alves, Frauke, Andrews, Anne M., Ashraf, Sumaira, Balogh, Lajos P., Ballerini, Laura, Bestetti, Alessandra, Brendel, Cornelia, Bosi, Susanna, Carril, Monica, Chan, Warren C. W., Chen, Chunying, Chen, Xiaodong, Chen, Xiaoyuan, Cheng, Zhen, Cui, Daxiang, Du, Jianzhong, Dullin, Christian, Escudero, Alberto, Feliu, Neu, Gao, Mingyuan, George, Michael, Gogotsi, Yury, Grünweller, Arnold, Gu, Zhongwei, Halas, Naomi J., Hampp, Norbert, Hartmann, Roland K., Hersam, Mark C., Hunziker, Patrick, Jian, Ji, Jiang, Xingyu, Jungebluth, Philipp, Kadhiresan, Pranav, Kataoka, Kazunori, Khademhosseini, Ali, Kopeček, Jindřich, Kotov, Nicholas A., Krug, Harald F., Lee, Dong Soo, Lehr, Claus Michael, Leong, Kam W., Liang, Xing Jie, Ling Lim, Mei, Liz Marzán, Luis M., Ma, Xiaowei, Macchiarini, Paolo, Meng, Huan, Möhwald, Helmuth, Mulvaney, Paul, Nel, Andre E., Nie, Shuming, Nordlander, Peter, Okano, Teruo, Oliveira, Jose, Park, Tai Hyun, Penner, Reginald M., Prato, Maurizio, Puntes, Victor, Rotello, Vincent M., Samarakoon, Amila, Schaak, Raymond E., Shen, Youqing, Sjöqvist, Sebastian, Skirtach, Andre G., Soliman, Mahmoud G., Stevens, Molly M., Sung, Hsing Wen, Tang, Ben Zhong, Tietze, Rainer, Udugama, Buddhisha N., Vanepps, J. Scott, Weil, Tanja, Weiss, Paul S., Willner, Itamar, Wu, Yuzhou, Yang, Lily, Yue, Zhao, Zhang, Qian, Zhang, Qiang, Zhang, Xian En, Zhao, Yuliang, Zhou, Xin, Parak, Wolfgang J., German Academic Exchange Service, Chinese Academy of Sciences, National Natural Science Foundation of China, National Basic Research Program (China), European Commission, Ministerio de Economía y Competitividad (España), Generalitat de Catalunya, Swiss National Science Foundation, Julian Schwinger Foundation, Claude Leon Foundation, National Science Foundation (US), Canadian Institutes of Health Research, Natural Sciences and Engineering Research Council of Canada, Alexander von Humboldt Foundation, Lars Hierta Memorial Foundation, Eusko Jaurlaritza, Research Grants Council (Hong Kong), National Cancer Institute (US), Junta de Andalucía, Research Foundation - Flanders, and German Research Foundation
- Subjects
Technology ,Chemistry, Multidisciplinary ,neurons ,General Physics and Astronomy ,02 engineering and technology ,Settore BIO/09 - Fisiologia ,01 natural sciences ,Engineering (all) ,Drug Delivery Systems ,Imaging tools ,Neoplasms ,Medicine and Health Sciences ,Nanotechnology ,General Materials Science ,Diverse applications ,nanomaterials ,Wearable technology ,Drug Carriers ,Chemistry, Physical ,General Engineering ,021001 nanoscience & nanotechnology ,Wearable devices ,3. Good health ,Chemistry ,Nanomedicine ,Physical Sciences ,QUANTUM-DOT BARCODES ,Science & Technology - Other Topics ,Medicine ,Materials Science (all) ,0210 nano-technology ,Nano Focus ,Materials science ,Materials Science ,Physics and Astronomy (all) ,Materials Science, Multidisciplinary ,010402 general chemistry ,MESENCHYMAL STEM-CELLS ,Vaccine development ,TARGETED DRUG-DELIVERY ,LABEL-FREE DETECTION ,MESOPOROUS SILICA NANOPARTICLES ,High throughput screening ,MD Multidisciplinary ,Animals ,Humans ,SURFACE-PLASMON RESONANCE ,Nanoscience & Nanotechnology ,Particle Size ,cell physiology ,FIELD-EFFECT TRANSISTOR ,Biomedicine ,Science & Technology ,carbon nanotubes ,business.industry ,COATED GOLD NANOPARTICLES ,neurology ,IRON-OXIDE NANOPARTICLES ,Biology and Life Sciences ,Data science ,nanomedicine, neurology, nanomaterials, carbon nanotubes, cell physiology, neurons ,0104 chemical sciences ,Physics and Astronomy ,Targeted drug delivery ,Nanoscale size ,Nanoparticles ,ENHANCED RAMAN-SCATTERING ,Drug Delivery ,business - Abstract
The design and use of materials in the nanoscale size range for addressing medical and health-related issues continues to receive increasing interest. Research in nanomedicine spans a multitude of areas, including drug delivery, vaccine development, antibacterial, diagnosis and imaging tools, wearable devices, implants, high-throughput screening platforms, etc. using biological, nonbiological, biomimetic, or hybrid materials. Many of these developments are starting to be translated into viable clinical products. Here, we provide an overview of recent developments in nanomedicine and highlight the current challenges and upcoming opportunities for the field and translation to the clinic., This work was supported by the Deutscher Akademischer Austauschdienst (DAAD to Philipps Universität Marburg and Zhejiang University, Hangzhou), the Chinesisch Deutsches Zentrum für Wissenschaftsförderung (“CDZ” to Z.G. and W.J.P.), and the Chinese Academy of Science (CAS). Part of this work was supported by the National Natural Science Foundation (51390481, 81227902, 81625011), National Basic Research Program (2014CB931900) of China (to Y.S.), by the European Commission grant Futurenanoneeds (to V.P. and W.J.P.), by the Spanish Ministerio de Economia y Competitividad (CTQ2011-23167 and CTQ2014-59808R to R.A.A.P.), the Generalitat of Catalunya (2014-SGR-612 to R.A.A.P.), the Deutsche Forschungsgemeinschaft (DFG) (AL552/8-1 to R.T.), the Swiss National Science Foundation (NRP62 to P.H.), the Claude & Julianna Foundation (grant to P.H.), the National Science Foundation (NSF) grants CHE-1306928 (to R.P.) and ECS-0601345; CBET 0933384; CBET 0932823; and CBET 1036672 (to N.A.K.), Canadian Institute of Health Research (grant to W.C.W.C.), and Natural Sciences and Engineering Research Council of Canada (grant to W.C.W.C.). S.A. and B.P. acknowledge a fellowship from the Alexander von Humboldt Foundation. N.F. acknowledges the Lars Hiertas Minne Foundation. M.C. acknowledges Ikerbasque for a Research Fellow position. X.C. acknowledges the Intramural Research Program (IRP), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH). B.Z.T. acknowledges the Innovation and Technology Commission of Hong Kong (ITC-CNERC14SC01). The Pancreatic Cancer research of A.E.N. and H.M. was funded by the U.S. National Cancer Institute, NIH grant # U01CA198846. A.E. acknowledges Junta de Andalucía (Spain) for a Talentia Postdoc Fellowship, co-financed by the European Union's Seventh Framework Programme, grant agreement no 267226. A.G.S. acknowledges support by BOF (UGent) and FWO (Research Foundation Flanders). Part of this work was supported by the National Natural Science Foundation of China.
- Published
- 2017
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