1. Future of the particle replication in nonwetting templates (PRINT) technology.
- Author
-
Xu J, Wong DH, Byrne JD, Chen K, Bowerman C, and DeSimone JM
- Subjects
- Biopharmaceutics methods, Drug Design, Electromagnetic Fields, Electronics, Humans, Materials Testing, Particle Size, Prodrugs chemical synthesis, RNA, Small Interfering metabolism, Surface Properties, Nanomedicine methods, Nanoparticles chemistry, Nanotechnology methods
- Abstract
Particle replication in nonwetting templates (PRINT) is a continuous, roll-to-roll, high-resolution molding technology which allows the design and synthesis of precisely defined micro- and nanoparticles. This technology adapts the lithographic techniques from the microelectronics industry and marries these with the roll-to-roll processes from the photographic film industry to enable researchers to have unprecedented control over particle size, shape, chemical composition, cargo, modulus, and surface properties. In addition, PRINT is a GMP-compliant (GMP=good manufacturing practice) platform amenable for particle fabrication on a large scale. Herein, we describe some of our most recent work involving the PRINT technology for application in the biomedical and material sciences., (Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
- Published
- 2013
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