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Electrochemical reduction of CO2 presents a persistent challenge in achieving high selectivity and stability, particularly in acidic electrolytes. Here, we successfully engineer an efficient armor-like catalyst, comprising Fe nanoparticles within nitrogen-doped carbon (Fe@NC) based on a solvent-free mechanochemistry method followed by pyrolysis. Porous nitrogen-doped carbon shells served as an effective protective layer for the Fe nanoparticles, facilitating the conversion of CO2 to CO with an impressive FECO of 99.0% in acidic electrolytes. As a result, the armored Fe@NC sustained its catalytic activity throughout 14 hours electrolysis period. [ABSTRACT FROM AUTHOR]

Abstract: In this study, ibuprofen, a common non-steroidal anti-inflammatory drug with low water-solubility was used as a model drug for its nanosizing via a PGSS™ (particles from gas-saturated solutions)-based method. A modified PGSS™ process was employed to prepare PEG6000-ibuprofen composite particles after investigating the solid–liquid–gas phase equilibrium behavior of the PEG6000–ibuprofen–CO2 system. The composite powder was then dispersed into water to remove PEG6000 and obtain ibuprofen nanoparticles. The effects of pressure, temperature, and mass fraction of ibuprofen in the composite on the ibuprofen particle size and particle morphology were investigated. Results showed that spherical ibuprofen nanoparticles with diameter of 20–500nm were prepared at different conditions. Additionally, the dissolution rates of different ibuprofen particles were studied, indicating much faster dissolution of the obtained ibuprofen nanoparticles compared with the raw material and those from the direct physical mixing approach in the phosphate buffer solution (pH=7.2±0.02). This can be attributed to the reduced size and the reduced crystallinity of the ibuprofen particles from the modified PGSS™-based process. [Copyright &y& Elsevier]

Abstract: A supercritical fluid-based method is proposed to produce coenzyme Q10 (CoQ10) nanoparticles. First, CoQ10/polyethylene glycol 6000 composite particles are prepared by a modified PGSS (particles from gas-saturated solutions) process with controlling the flow rate of the gas-saturated solution. Then, CoQ10 nanoparticles are obtained by dissolving the composite particles into water. The effect of experimental variables of the modified PGSS process, including pressure, temperature, flow rate of the gas-saturated solution, and mass fraction of CoQ10, on the CoQ10 particle size and particle size distribution was investigated. Results show that CoQ10 slurry product with a median diameter of 190nm and yield of 89.8% can be prepared at an optimum condition (operating pressure of 25MPa, operating temperature of 80°C, gas-saturated solution flow rate of 1.02mL/min, CoQ10 mass fraction of 40% and nozzle diameter of 100μm) via the supercritical fluid-based method. [Copyright &y& Elsevier]