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Heavy metal ions (HMIs) have become a significant contaminant in recent years. The increase in heavy metal pollution is a serious situation, requiring progressively robust, fast sensing, highly sensitive, and suitable techniques for heavy metal detection. Compared to other classical analytical methods, electroanalytical techniques, especially stripping voltammetric techniques with modified screen-printed electrodes (SPEs), have several advantages, such as fast sensing, great sensitivity, specificity, and long-time stability. Therefore, these techniques are more suitable for HMI detection. In this review, the nanostructured materials used to coat SPEs for the electrochemical determination of HMI are summarized. Additionally, the electrode fabrication method, modification steps, and electroanalytical study of these materials are systematically discussed. Hence, this review will support the researchers in precisely evaluating the electrochemical HMIs detection through highly sensitive stripping voltammetric techniques using SPE modified with nanostructured carbon and their allotropes, metal, metal oxides and their nanocomposites as sensor materials. Moreover, modified electrodes real time detection of HMIs in different food and environmental samples were briefly discussed., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)

Electroanalytical and optical techniques are widely used in the development of nanomaterials-based sensor platforms. These techniques have a quick response, high sensitivity, and selectivity. Electroanalytical and optical techniques are widely used in the development of nanomaterial-based sensor platforms. These sensors must be able to detect biomarkers, pathogens, toxins, and pharmaceuticals in biological matrices associated with cardiovascular disease, cancer, and neurodegenerative diseases. Considering these pathophysiologies, numerous investigations have been undertaken to develop sensors for early diagnosis and treatment, utilizing nanomaterials such as quantum dots. Graphene quantum dots (GQDs), which are ideally nanometer-sized graphene fragments, have recently received increased attention due to their excellent physicochemical properties such as fast electron mobility, photostability, water solubility, biocompatibility, high specific surface area, and nontoxicity. Apart from the properties mentioned above, GQDs provide π–π interactions, electrostatic, and covalent interactions with an analyte, and ease of synthesis as well as the ability to combine with other nanomaterials, which have enabled their use in various sensing platforms. This review summarizes recent advances in GQDs-based nanocomposites for sensor applications, with a focus on electroanalytical and optical techniques, as well as current challenges and future prospects. [ABSTRACT FROM AUTHOR]