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Purpose: To compare higher-order aberrations (HOAs) after foldable phakic intraocular lens (pIOL) implantation and wavefront-guided photorefractive keratectomy (PRK) for the correction of myopia., Setting: Department of Ophthalmology, Medisch Centrum Haaglanden, Den Haag, The Netherlands., Design: Comparative case series., Methods: This retrospective comparative case series comprised eyes that had implantation of an Artiflex foldable pIOL or wavefront-guided PRK. Preoperative and postoperative refractive data, pupil diameter, endothelial cell density, and higher-order aberrations (HOAs) were measured and compared., Results: The median follow-up was 13 months in the pIOL group and 10 months in the PRK group. The mean spherical equivalent (SE) in the pIOL group was -5.50 diopters (D) ± 1.05 (SD) (range -3.25 to -7.13 D) preoperatively and -0.26 ± 0.28 D (range -0.88 to 0.38 D) postoperatively and the mean in the PRK group, -5.72 ± 0.88 D (range -4.25 to -7.50 D) and -0.03 ± 0.42 D (range -0.75 to 1.00 D), respectively. The postoperative SE was within ±0.50 D in 86.4% of eyes and 85.2% of eyes, respectively. Postoperatively, the significant changes in the pIOL group and the PRK group, respectively, were as follows: total HOAs, 0.03 μm and 0.26 μm (P = .001); trefoil-y, 0.09 μm and -0.04 μm (P = .004); spherical aberration, -0.05 μm and 0.21 μm (P = .002)., Conclusions: Foldable pIOL implantation increased total HOAs and spherical aberration less than wavefront-guided PRK to correct low to moderate myopia, suggesting foldable pIOL implantation maintains the cornea's prolate shape better., (Copyright © 2011 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.)

Purpose: To determine the effects of Artiflex phakic intraocular lens (PIOL) implantation on best spectacle-corrected high and low contrast visual acuity under photopic and mesopic conditions., Methods: Forty-two consecutive eyes had implantation of a foldable iris-supported PIOL to correct myopia. The mean preoperative spherical equivalent refraction was -7.26+/-1.91 diopters (D) (range: -4.90 to -13.60 D). The high (100%) and low (2.5%) contrast visual acuity with best spectacle correction was tested with translucent logarithmic visual acuity charts (Precision Vision) under photopic and mesopic conditions., Results: At mean 7.6+/-5.4 months after PIOL implantation, the mean high and low contrast visual acuity under photopic and mesopic conditions had significantly increased from preoperatively: photopic high contrast visual acuity from -0.07+/-0.11 logMAR to -0.14+/-0.08 logMAR (P<.001); photopic low contrast visual acuity from 0.48+/-0.14 logMAR to 0.36+/-0.11 logMAR (P=.011); mesopic high contrast visual acuity from -0.09+/-0.09 logMAR to -0.16+/-0.08 logMAR (P<.001); and mesopic low contrast visual acuity from 0.50+/-0.13 logMAR to 0.33+/-0.10 logMAR (P<.001). Mean postoperative spherical equivalent refraction was -0.21+/-0.28 D (range: +0.50 to -0.75 D). Of all eyes, 91.9% were within 0.50 D of attempted correction, and 67% gained 1 or more lines of best spectacle-corrected visual acuity (BSCVA). No eye lost 2 or more lines of BSCVA., Conclusions: Artiflex PIOL implantation for the correction of moderate to high myopia seems to be a safe and predictable procedure, which resulted in increased high and low contrast visual acuity under photopic and mesopic conditions., (Copyright 2010, SLACK Incorporated.)