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Purpose: To study the morphologic alterations around the optic disc by spectral optical coherence tomography (SD OCT) in eyes with high myopia., Patients and Methods: Two hundred eyes (113 patients) with high myopia were included. The participants had complete ophthalmologic examinations and OCT examinations. OCT scans were obtained around the optic in each patient., Results: We detected by OCT, a peripapillary detachment in 14 eyes (11.0%), a retinischisis peripapillary in 10 eyes (5%) and paravascular abnormalities as microfolds and paravascular cysts in 80 eyes (40%). A statistically significant difference was found between patients with microfolds paravascular and the rest of the patients concerning age (P=0.0034) and axial length (P=0.001). The patients with paravascular cysts were older (P=0.0022), had a greater axial length (P=0.0044) and a high rate of posterior staphyloma compared to other patients., Conclusion: Perpapillary changes detected by SD OCT in eyes in high myopia are relatively frequent and don't always present a clinical or ophthalmoscopic changes., (Copyright © 2014 Elsevier Masson SAS. All rights reserved.)

Purpose: To investigate the factors linked to foveoschisis in high myopia., Methods: Retrospective study of 113 patients (200 eyes) with high myopia was conducted between January 2010 and June 2012. Subjects underwent a complete ophthalmic examination, spectral domain optical coherence tomography (OCT TOPCON 2000) and ocular echography., Results: Of the 200 eyes, 22 (11%) had foveoschisis on OCT examination. On the basis of univariate analysis, five variables were associated with the pathologic changes, including spherical equivalent over 10 diopters (P=0.044), axial length over 30 mm (P=0.0028), macular chorioretinal atrophy (P=0.0009), posterior staphyloma (P=0.0007) and vitreoretinal interface factors (P=0.0002). In the multivariate analysis, three factors were independently associated with foveoschisis in high myopia: axial length (adjusted OR, 16.7; IC 95% 1.4-219.7, P=0.036), macular chorioretinal atrophy (adjusted OR, 13.2; IC 95%, 1.3-133.1, P=0.044), and vitreoretinal interface factors (adjusted OR, 36.1; IC 95%, 3.5-376.9, P=0.002)., Conclusions: In our study, axial length, macular chorioretinal atrophy, and vitreoretinal interface factors were independently associated foveoschisis in highly myopic eyes., (Copyright © 2014 Elsevier Masson SAS. All rights reserved.)

Purpose To investigate the morphologic alterations around the optic disc by SD‐OCT with high myopia Methods One hundred eyes (54 patients) with high myopia (>‐6.00 diopters) were included. The participants had ophthalmologic examinations including stereoscopic fundus observations, OCT examinations. For OCT, multiple horizontal and vertical and cercle scans were obtained around the optic disc and fovea in each patient. Results Patients were mean age 43.2+/‐9.4 years, with a spherical‐equivalent refractive error of ‐11.26+/‐4.85 D and mean axial length of 27.65+/‐1.82 mm. A peripapillary detachment was detected by OCT in 8 eyes (8%) as a hyporeflective space intrachoroidally and subretinally. It was also observed within the tissue posterior to the conus in eyes without the typical ophthalmoscopic yellow‐orange lesions. Microfolds in the retinal vessels were detected at the conus edge in 40 of the highly myopic eyes (40%), and 10 of these eyes had paravascular cysts (10%). A retinoschisis was present at the site of the retinal vessels in 10 eyes (10%). Conclusion The SD OCT examinations demonstrated different types of peripapillary changes in highly myopic eyes. It is important to detect these peripapillary changes especially peripapillary detachment by OCT to be able to predict the later development of visually disabling conditions. [ABSTRACT FROM AUTHOR]