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Start Over Author "Frederiks, Aaron J." Topic mycosis fungoides
1 results on '"Frederiks, Aaron J."'

1. Complete remission of stage IV erythrodermic mycosis fungoides with large cell transformation through combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation.

Author

Frederiks AJ, Creeper KJ, Spagnolo DV, Cannell P, and Radeski D

Subjects
Aminopterin therapeutic use, Female, Humans, Middle Aged, Mycosis Fungoides pathology, Remission Induction, Skin Neoplasms pathology, Treatment Outcome, Aminopterin analogs & derivatives, Antibiotics, Antineoplastic therapeutic use, Depsipeptides therapeutic use, Hematopoietic Stem Cell Transplantation, Mycosis Fungoides therapy, Skin Neoplasms therapy
Abstract

We report the case of a 59-year-old woman with stage IV erythrodermic mycosis fungoides (MF) and large cell transformation who, despite failing multiple previous treatments, achieved complete remission through a combination of pralatrexate and romidepsin followed by allogeneic hematopoietic stem cell transplantation (alloSCT). Further studies are needed in focussing on this combined regimen in treating cutaneous T-cell lymphoma (CTCL) and its efficacy as a bridging regimen in facilitating successful alloSCT., (© 2021 The Australasian College of Dermatologists.)

Published
2021
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