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1. Cyclic mechanical strain-induced proliferation and migration of human airway smooth muscle cells: role of EMMPRIN and MMPs.

Author

Hasaneen, Nadia A., Zucker, Stanley, Jian Cao, Chiarelli, Christian, Panettieri, Reynold A., and Foda, Hussein D.

Subjects
CELL migration, CELL proliferation, EXTRACELLULAR matrix proteins, MUSCLE cells, SMOOTH muscle, METALLOPROTEINASES, EXTRACELLULAR matrix
Abstract

Presents findings of a study which determined the role of the mechanical strain of human airway smooth muscle (HASM) cells in inducing their proliferation and migration. Contribution of matrix metalloproteinases (MMP) to strain-induced HASM proliferation and migration; Integration of extracellular matrix metalloproteinase inducer within HASM cells; Role of MMP in HASM cell migration and invasion; Effect of cyclic strain of HSM on Tenascin-C release.

Published
2005
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