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23 results on '"Denison, M"'

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1. Proteolytic Processing of the Coronavirus Replicase Nonstructural Protein 14 Exonuclease Is Not Required for Virus Replication but Alters RNA Synthesis and Viral Fitness.

2. Mouse hepatitis virus replicase protein complexes are translocated to sites of M protein accumulation in the ERGIC at late times of infection.

3. MHV-A59 gene 1 proteins are associated with two distinct membrane populations.

4. The cell biology of coronavirus infection.

5. Mouse hepatitis virus replicase proteins associate with two distinct populations of intracellular membranes.

6. Four proteins processed from the replicase gene polyprotein of mouse hepatitis virus colocalize in the cell periphery and adjacent to sites of virion assembly.

7. Localization of mouse hepatitis virus nonstructural proteins and RNA synthesis indicates a role for late endosomes in viral replication.

8. The putative helicase of the coronavirus mouse hepatitis virus is processed from the replicase gene polyprotein and localizes in complexes that are active in viral RNA synthesis.

9. Mouse hepatitis virus 3C-like protease cleaves a 22-kilodalton protein from the open reading frame 1a polyprotein in virus-infected cells and in vitro.

10. Expression, purification, and activity of recombinant MHV-A59 3CLpro.

11. Processing of the MHV-A59 gene 1 polyprotein by the 3C-like proteinase.

12. Determinants of mouse hepatitis virus 3C-like proteinase activity.

13. Intracellular and in vitro-translated 27-kDa proteins contain the 3C-like proteinase activity of the coronavirus MHV-A59.

14. Identification and characterization of a serine-like proteinase of the murine coronavirus MHV-A59.

15. Coronavirus protein processing and RNA synthesis is inhibited by the cysteine proteinase inhibitor E64d.

16. Identification and characterization of a 65-kDa protein processed from the gene 1 polyprotein of the murine coronavirus MHV-A59.

17. Inhibition of coronavirus MHV-A59 replication by proteinase inhibitors.

18. Coronavirus polyprotein processing.

19. A newly identified MHV-A59 ORF1a polypeptide p65 is temperature sensitive in two RNA negative mutants.

20. Intracellular processing of the N-terminal ORF 1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events.

22. Identification of putative polymerase gene product in cells infected with murine coronavirus A59.

23. Translation and processing of mouse hepatitis virus virion RNA in a cell-free system.

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