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Your search keyword '"Orr, Meghan J."' showing total 1 results
Start Over Author "Orr, Meghan J." Topic multicomponent reactions
1 results on '"Orr, Meghan J."'

1. Acid‐Promoted Cascade Reaction of <italic>N</italic>‐(4‐Chloroquinolin‐3‐yl)carbamates with Amines: One‐Pot Assembly of Imidazo[4,5‐<italic>c</italic>]quinolin‐2‐ones.

Author

Lu, Xiao, Kim, Myunghoon, Orr, Meghan J., Li, Hao, and Huang, Wenwei

Subjects
CARBAMATES, AMINES, CHEMICAL bonds, CHEMICAL derivatives, SUZUKI reaction
Abstract

An acid‐promoted cascade reaction of N‐(4‐chloroquinolin‐3‐yl)carbamates with amines is described. This method achieves the formation of two new C–N bonds through an intermolecular amination/intramolecular cyclization reaction sequence. In combination with a subsequent Suzuki coupling reaction, this three‐component telescopic procedure provides rapid access to various bioactive imidazo[4,5‐c]quinolin‐2‐one derivatives. [ABSTRACT FROM AUTHOR]

Published
2018
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