1. Nonbubble‐Propelled Biodegradable Microtube Motors Consisting Only of Protein.
- Author
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Sugai, Natsuho, Morita, Yoshitsugu, and Komatsu, Teruyuki
- Subjects
- *
MOLECULAR motor proteins , *PROTEINS , *UREASE , *PROTEIN synthesis , *MOTORS - Abstract
This paper describes the synthesis of protein microtube motors having a urease interior surface and highlights their nonbubble‐propelled behavior driven by enzymatic reaction (urea→NH3 and CO2). The precursor microtubes were prepared by layer‐by‐layer assembly using a track‐etched microporous polycarbonate membrane. Immobilization of a urease on the internal wall was accomplished using avidin–biotin interaction. The tubules swam smoothly in an aqueous media containing a physiological concentration of urea. Each tubule was rotating laterally while moving forward. It is remarkable that the microtubes were digested completely by proteases, demonstrating perfect biodegradability. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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