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Lateral epicondylitis (LE) is a common overuse injury related to a mechanical overload of the wrist extensors' origin; however, some patients also complain of clumsiness suggesting a possible motor control problem. The purpose of this study was to examine for differences in fine motor control ability between subjects with LE and matched control subjects. Subtests of the Purdue Pegboard Test (PPT) and the Complete Manual Dexterity Test (CMDT) were administered to 28 subjects with LE, and 28 age, gender, and hand dominance-matched control subjects. The LE group demonstrated a significant decrease in fine motor control ability on both measures, compared with the control group on both the PPT, F(1,52)=9.98, P=0.003, and the CMDT, F(1,52)=18.11, P=0.001. There appeared to be no effect for the length of time since injury. There were significant differences in fine motor control ability between individuals with LE and a matched control group for both measures used. These results suggest that tests of fine motor control should be considered in the assessment of clients with LE. The mechanism related to the deficit is unknown and warrants further research.