Search

Background: Guillain-Barré syndrome (GBS) is a rare disease that consists of a group of neuropathic conditions. Very few epidemiological studies of GBS have been carried out in Spain. The aim of this study was to determine the trends in GBS mortality in the total population of Spain for the period 1999 to 2013., Methods: Data on GBS deaths were drawn from the National Statistics Institute of Spain. Crude and overall age-standardised GBS mortality rates were calculated and joinpoint regression models were used to describe trend changes. Mean age of deceased by GBS each year was also assessed., Results: The overall age-standardised GBS mortality rate was 0.71 per million in 1999 and 0.40 in 2013. It was higher in men, 1.08 vs. 0.42 in 1999 and 0.48 vs. 0.35 in 2013. There was a statistically significant decrease in mortality during the study period. All the age-standardised mortality rates decreased (overall and by gender) from 1999 to 2013. The mean age at death increased with time, from 73 years in 1999 to 77 years in 2013., Conclusions: GBS mortality has improved in Spain during the last 15 years. The age of death has risen and the mortality rate has decreased.

Objective: To describe the evolution of the number of potential years of life lost (PYLL) because of AIDS in La Rioja between 1986 and 1993., Design: Descriptive study., Setting: Autonomous Community of La Rioja., Patients and Other Participants: Secondary data from the regional Register of AIDS cases in La Rioja, from the Register of Deaths in La Rioja and from the mortality statistics found in the National Statistics Institute., Measurements and Main Results: From 1986 the increase in PYLL because of AIDS as a percentage of all causes of premature death was constant. If proportional mortality because of AIDS is grouped in two periods (1986-1989 and 1990-1993), in the first period and for men 1.1% of all PYLL were due to AIDS, whereas in the second this figure was 7.7%. For women these figures went from 0.7 to 8,5. Expressed as a risk, for men the probability that PYLL was due to AIDS was 4 times greater in the second period than in the first. For women this probability was 12 times greater in the second period than in the first. Among men the rates of PYLL adjusted for age kept roughly constant or with a light downward tendency for all the causes studied except AIDS, which occupied second place in the last year studied. Rates of PYLL adjusted for age were more irregular over the years in the case of women, but the increase in AIDS was notable and in 1993 took third place., Conclusions: Interpreting the results of this study enables the impact of AIDS on premature mortality in La Rioja to be quantified.

The article presents a study which examined the trends in the systemic lupus erythematosus (SLE) mortality in Spain from 1981-2010. The researchers gathered data on SLE deaths from the National Statistics Institute of Spain. They found that overall age-standardized SLE mortality rate in 1981 reached 1.82 per million and 2.24 per million in 2010. They indicated the increase in the overall-age standardized SLE mortality rate from 1981-1999 and the stabilization of mortality rate from 2000-2010.