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17,108 results on '"Tumor Suppressor Protein p53"'

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1. Transcriptomic Landscape Analysis Reveals a Persistent DNA Damage Response in Metabolic Dysfunction-associated Steatohepatitis Post-dietary Intervention.

2. MicroRNA-21 is a potential link between non-alcoholic fatty liver disease and hepatocellular carcinoma via modulation of the HBP1-p53-Srebp1c pathway

3. Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury

4. Phase separation of p53 induced by its unstructured basic region and prevented by oncogenic mutations in tetramerization domain

5. Coiled-coil domain containing 3 suppresses breast cancer growth by protecting p53 from proteasome-mediated degradation

6. EXOSC8 promotes colorectal cancer tumorigenesis via regulating ribosome biogenesis-related processes

7. USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma

8. A common pathway to cancer: Oncogenic mutations abolish p53 oscillations

9. Deletion of Smurf1 attenuates liver steatosis via stabilization of p53

10. CRISPR-based kinome-screening revealed MINK1 as a druggable player to rewire 5FU-resistance in OSCC through AKT/MDM2/p53 axis

11. Mitochondria-targeting folic acid-modified nanoplatform based on mesoporous carbon and a bioactive peptide for improved colorectal cancer treatment

12. Neat1 promotes acute kidney injury to chronic kidney disease by facilitating tubular epithelial cells apoptosis via sequestering miR-129-5p

13. Clonal evolution in chronic lymphocytic leukemia is associated with an unmutated IGHV status and frequently leads to a combination of loss of TP53 and TP53 mutation

14. RNA sequencing reveals lncRNA-mediated non-mendelian inheritance of feather growth change in chickens

15. The C-terminus of Gain-of-Function Mutant p53 R273H Is Required for Association with PARP1 and Poly-ADP-Ribose

16. Proteasomal and autophagy-mediated degradation of mutp53 proteins through mitochondria-targeting aggregation-induced-emission materials

17. Chlorambucil-conjugated PI-polyamides (Chb-M’), a transcription inhibitor of RUNX family, has an anti-tumor activity against SHH-type medulloblastoma with p53 mutation

18. Understanding the interaction of 14-3-3 proteins with hDMX and hDM2

19. Involvement of the p53/p21 complex in p53-dependent gene expression

20. Thymol has anticancer effects in U-87 human malignant glioblastoma cells

21. CTPS1 inhibition suppresses proliferation and migration in colorectal cancer cells

22. Enhancement of MDM2 inhibitory effects through blocking nuclear export mechanisms in ovarian cancer cells

23. Activation of p53: How phosphorylated Ser15 triggers sequential phosphorylation of p53 at Thr18 by <scp>CK1δ</scp>

24. Identification of mutant p53-specific proteins interaction network using TurboID-based proximity labeling

25. Evolution of germline TP53 variant classification in children with cancer

26. The role of autophagy in cadmium-induced acute toxicity in glomerular mesangial cells and tracking polyubiquitination of cytoplasmic p53 as a biomarker

27. Predictive value of p53, Ki67 and TLR5 in neoplastic progression of Barrett’s esophagus: a matched case–control study

28. RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2

29. CHMP1A suppresses the growth of renal cell carcinoma cells via regulation of the PI3K/mTOR/p53 signaling pathway

30. Decreased EMILIN2 correlates to metabolism phenotype and poor prognosis of ovarian cancer

31. Ezh2 competes with p53 to license lncRNA Neat1 transcription for inflammasome activation

32. Motor unit recovery following Smn restoration in mouse models of spinal muscular atrophy

33. RDIVpSGP motif of ASPP2 binds to 14-3-3 and enhances ASPP2/k18/14-3-3 ternary complex formulation to promote BRAF/MEK/ERK signal inhibited cell proliferation in hepatocellular carcinoma

34. Deciphering the mechanism of p73 recognition of p53 response elements using the crystal structure of p73-DNA complexes and computational studies

35. Compound cellular stress maximizes apoptosis independently of p53 in glioblastoma

36. LncRNA RUNX1-IT1 affects the differentiation of Th1 cells by regulating NrCAM transcription in Graves' disease

37. Deciphering the acetylation code of p53 in transcription regulation and tumor suppression

38. Targeting the miR-34a/LRPPRC/MDR1 axis collapse the chemoresistance in P53 inactive colorectal cancer

39. Exosomes Derived from Senescent Endothelial Cells Contain Distinct Pro-angiogenic miRNAs and Proteins

40. Of the many cellular responses activated by TP53, which ones are critical for tumour suppression?

41. The genotypes and phenotypes of missense mutations in the proline domain of the p53 protein

42. Induction of Apoptosis and Autophagy by Ternary Copper Complex Towards Breast Cancer Cells

43. A Novel Imidazo[1,2-a]pyridine Compound Reduces Cell Viability and Induces Apoptosis of HeLa Cells by p53/Bax-Mediated Activation of Mitochondrial Pathway

44. Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death

45. Cell cycle regulation: p53-p21-RB signaling

46. Preclinical activity of fluvastatin‐loaded self‐nanoemulsifying delivery system against breast cancer models: Emphasis on apoptosis

47. Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence

48. Characterization of chikusetsusaponin IV and V induced apoptosis in HepG2 cancer cells

49. TP53 mutations in head and neck cancer

50. Treatments targeting autophagy ameliorate the age-related macular degeneration phenotype in mice lacking APOE (apolipoprotein E)

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