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We investigate nonequilibrium stationary distributions induced by stochastic dichotomous noise in double-well and multiwell models of ion channel gating kinetics. The channel kinetics is analyzed using both overdamped Langevin equations and master equations. With the Langevin equation approach we show a nontrivial focusing effect due to the external stochastic noise, namely, the concentration of the probability distribution in one of the two wells of a double-well system or in one or more of the wells of the multiwell model. In the multiwell system, focusing in the outer wells is shown to be achievable under physiological conditions, while focusing in the central wells has proved possible so far only at very low temperatures. We also discuss the strength of the focusing effect and obtain the conditions necessary for maximal focusing to appear. These conditions cannot be predicted by a simple master equation approach.

Using the phenomenological expression for the level spacing distribution with only one parameter 0 ≤ β ≤ ∞ covering all regimes of chaos and complexity in a quantum system, we show that transport properties of the one-dimensional Anderson model of finite size can be expressed in terms of this parameter. Specifically, we demonstrate a strictly linear relation between β and the normalized localization length for the whole transition from strongly localized to extended states. This result allows one to describe all transport properties in the open system entirely in terms of the parameter β and the strength of the coupling to the continuum. For nonperfect coupling, our data show a quite unusual interplay between the degree of internal chaos defined by β and the degree of openness of the model. The results can be experimentally tested in single-mode waveguides with either bulk or surface disorder.