Producing an accurate and valid mineral prospectivity map is one of the most significant parts of mineral exploration studies. For this purpose, it is needed to obtain valid evidential layers and integrate them with an accurate methodology. Knowledge and data‐driven methods are two primary techniques applied to combine various evidential layers for mineral prospectivity mapping, of which each of them includes a variety of analytical techniques. In this study, in the first step, satellite data, aeromagnetic and airborne radiometric data, stream sediment geochemical data and geological data were applied to create valid remote sensing, geophysical, geochemical, lineaments and lithological evidential layers of the study area that are an essential factor in recognition porphyry copper mineralization, then in the second step, based on the known mineralization occurrences data, the evidential layers were weighted. Finally, these layers were integrated using fuzzy logic and index overlay methods in a combination of knowledge and data‐driven way. Validation of each layer was done using available data in the second step. The final mineral prospectivity map was evaluated, and the confirmation of this layer detected that the final mineral prospectivity map obtained from data‐driven multi‐index overlay method has a higher ore prediction rate of 76%, which identifies 24% of the area as potential zones for further exploration. [ABSTRACT FROM AUTHOR]