1. Short-term PM exposure and social stress cause pulmonary and cardiac dysfunction
- Author
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David M. Aslaner, Ty A. Saldaña, Duncan M. MacKenzie, Devin R. O’Piela, Roy A. Miller, Neill A. Schwieterman, Michael J. Falvo, Matthew W. Gorr, and Loren E. Wold
- Subjects
Male ,Air Pollutants ,Mice ,Heart Diseases ,Air Pollution ,Animals ,Particulate Matter ,General Medicine ,Environmental Exposure ,Toxicology ,Lung ,Methacholine Chloride ,Stress, Psychological - Abstract
Ambient particulate matter (PM) exposure increases risk for cardiopulmonary health problems which may be exacerbated in a stressful environment. Co-exposure to PM and stress characterizes the experience of many deployed military personnel and first responders but has not been thoroughly investigated. This is especially relevant to military personnel who have been exposed to high PM levels in conjunction with stressful military conflict situations. To understand the mechanisms and time-course of the health consequences following burn pit exposure, we exposed mice to moderate levels of ambient PM less than 2.5 μM in diameter (PM
- Published
- 2022