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Abstract Background Decompressive laminectomy (DI) is a standard operation for lumbar spinal stenosis (LSS) patient with severe claudication symptoms for many years. However, patients whose symptom severity does not meet undergoing invasive surgery make therapeutic options into dilemma. Interspinous spacers (ISP) bridge the gap between surgical interventions and CC in management of LSS. In our study, we aim to systematically assess the two FDA-approved interspinous spacers for treatment of lumbar spinal stenosis: Superion versus X-STOP. Methods Electronic databases, including PubMed, Embase, MEDLINE, Cochrane Library were searched to retrieve clinical trials concerning the comparison between Superion and X-STOP in treatment for lumbar spinal stenosis before April 2017. The following outcome measures were extracted: (1) Zurich Claudication Questionnaire (ZCQ) patient satisfaction score, (2) axial pain severity, (3) extremity pain severity, (4) back-specific functional impairment, (5) reoperation, and (6) complication. The data analysis was conducted with Review Manager 5.3. Results Five randomized controlled trials (RCTs) with 1118 patients were included in this meta-analysis. The pooled analysis indicated that the Superion group is superior to X-STOP in axial pain severity (SMD: 0.03; 95% CI 0.15, 0.45; p

Objective: To evaluate the effectiveness of different acupuncture treatments in the treatment of lumbar disc herniation. Methods: Searching PubMed, EMBASE, Cochrane Library, web of by computer Science, Chinese Journal Full-text Database, Wanfang database, VIP database and Chinese biomedical literature database, the retrieval time is from the establishment of the database to January 1, 2020. Two researchers conducted literature screening, quality evaluation and data extraction according to the nano platoon standard, and used stata16.0 for network meta-analysis. Results: a total of 69 RCTs were included, involving 6168 patients with lumbar disc herniation, 5 kinds of acupuncture therapy (warm acupuncture, fire acupuncture, electroacupuncture, acupuncture thread embedding, general acupuncture). The results of network meta-analysis showed that the effect of electroacupuncture was inferior to that of warm acupuncture, acupuncture thread embedding, and the effect of general acupuncture was inferior to that of warm acupuncture, fire acupuncture, electroacupuncture, acupuncture thread embedding, and the difference was statistically significant. In terms of efficiency, acupuncture and moxibustion embedding thread > warming acupuncture and moxibustion > fire acupuncture > electroacupuncture > ordinary acupuncture. Conclusion: in the treatment of lumbar disc herniation, the clinical effect of acupuncture thread embedding is better than the other four interventions. However, the quality and quantity of literature in this study are limited, and the conclusion of this study needs to be verified by high-quality RCT with multiple centers and large samples. [ABSTRACT FROM AUTHOR]

Objective: To explore the clinical effect of Duhuo Jisheng Decoction in the treatment of lumbar disc herniation. Methods: CNKI, VIP, Wan Fang Data, Pubmed, Cochrane Library, Medline Complete and Embase databases were searched by computer. The randomized controlled trial (RCT) of Duhuo Jisheng Decoction combined with western medicine in the treatment of lumbar intervertebral disc herniation was studied. The searching time was from the establishment of the database to July 20, 2019. Data were extracted and analyzed by Revman 5.3 software. Results: Twenty-four literatures involving 1980 patients were included. Meta-analysis showed that the total effective rate of Duhuo Jisheng Decoction group was significantly higher (OR = 5.26, 95% CI (4.13, 6.69), Z = 13.47, P < 0.00001) and the incidence of adverse reactions was significantly lower (OR = 0.45, 95% CI (0.23, 0.87), Z = 2.36, P = 0.00001) than that of Western medicine group. 02). Conclusion: Duhuo Jisheng Decoction is effective and safe in the treatment of lumbar intervertebral disc herniation. However, the literature included in this study is limited, and the quality of the literature is low. It is necessary to carry out in-depth verification of high-quality, large-sample RCT. [ABSTRACT FROM AUTHOR]