21 results on '"Jin, Xi"'
Search Results
2. Percutaneous tibial nerve stimulation for overactive bladder syndrome: a systematic review and meta-analysis
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Wang, Menghua, Jian, Zhongyu, Ma, Yucheng, Jin, Xi, Li, Hong, and Wang, Kunjie
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- 2020
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3. Vitamin E and Multiple Health Outcomes: An Umbrella Review of Meta-Analyses.
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Xiong, Zheyu, Liu, Linhu, Jian, Zhongyu, Ma, Yucheng, Li, Hong, Jin, Xi, Liao, Banghua, and Wang, Kunjie
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The relationship between vitamin E intake or circulating α-tocopherol and various health outcomes is still debatable and uncertain. We conducted an umbrella review to identify the relationships between vitamin E intake or circulating tocopherol and health outcomes by merging and recalculating earlier meta-analyses. The connections that were found to be statistically significant were then classified into different evidence levels based on p values, between-study heterogeneity, prediction intervals, and small study effects. We finally included 32 eligible meta-analyses with four vitamin E sources and 64 unique health outcomes. Only the association between circulating α-tocopherol and wheeze or asthma in children was substantiated by consistent evidence. Suggestive evidence was suggested for seven results on endothelial function (supplemental vitamin E): serum C-reactive protein (CRP) concentrations (supplemental vitamin E), cervical cancer (dietary vitamin E), esophageal cancer (dietary vitamin E), cervical intraepithelial neoplasia (CIN, dietary vitamin E), pancreatic cancer (total vitamin E intake), and colorectal cancer (circulating α-tocopherol levels); all of these showed a protective effect consistent with the vitamin E source. In conclusion, our work has indicated that vitamin E is protective for several particular health outcomes. Further prospective studies are required when other factors that may contribute to bias are considered. [ABSTRACT FROM AUTHOR]
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- 2023
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4. The Effect of Preoperative Tamsulosin on Ureteral Navigation, Operation, and Safety: A Systematic Review and Meta-Analysis.
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Cheng, Chao, Ma, Yucheng, Wen, Jun, Xiang, Liyuan, and Jin, Xi
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TAMSULOSIN ,URETEROSCOPY ,RANDOMIZED controlled trials ,POSTOPERATIVE pain ,NAVIGATION - Abstract
Introduction: Urolithiasis is one of the most common diseases in the world, and at present, ureteroscopy (URS) is the first choice for its treatment. Although the effect is good, there is a risk of insertion failure of ureteroscope. Tamsulosin, as an α-receptor blocker, has the function of relaxing ureteral muscles, and can help stones to be discharged from ureteral orifice. In this study, we aimed to determine the effect of preoperative tamsulosin on ureteral navigation, operation, and safety. Methods: This study was conducted and reported according to the meta-analysis extension of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The PubMed and Embase databases were searched for studies. Data were extracted according to the PRISMA principles. We collected and combined randomized controlled trial and researches in reviews of preoperative tamsulosin to explore the effect of preoperative tamsulosin on ureteral navigation, operation, and safety. A data synthesis was performed using RevMan 5.4.1 software (Cochrane). Heterogeneity was mainly evaluated with I2 tests. Key metrics include: success rate of ureteral navigation, time of URS, stone-free rate, and postoperative symptoms. Result: We summarized and analyzed 6 studies. We noted a statistically significant improvement in the success rate of ureteral navigation (Mantel-Haenszel [M-H], odds ratio [OR]: 3.78, 95% confidence interval [CI]: [2.34, 6.12], p < 0.01) and stone-free rate (M-H, OR: 2.25, 95% CI: [1.16, 4.36], p = 0.02) with tamsulosin preoperatively. At the same time, we also observed that postoperative fever (M-H, OR: 0.37, 95% CI: [0.16, 0.89], p = 0.03) and postoperative analgesia (M-H, OR: 0.21, 95% CI: [0.05, 0.92], p = 0.04) were also reduced because of preoperative tamsulosin. Conclusion: Preoperative tamsulosin can not only increase the one-time success rate of ureteral navigation and the stone-free rate of URS but also reduce the incidence of postoperative adverse symptoms such as postoperative fever and postoperative pain. [ABSTRACT FROM AUTHOR]
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- 2023
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5. Comparison of Contrast-Enhanced Ultrasound vs Conventional Ultrasound-Guided Percutaneous Nephrolithotomy in Nondilated Collecting System: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
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Ma, Yucheng, Li, Puhan, Xiang, Liyuan, Wen, Jun, and Jin, Xi
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CONTRAST-enhanced ultrasound ,RANDOMIZED controlled trials ,PERCUTANEOUS nephrolithotomy ,NEPHROSTOMY ,ODDS ratio - Abstract
Background: It has been demonstrated that ultrasound (US)-guided renal collecting system access during percutaneous nephrolithotomy (PCNL) is efficient and secure. The puncture success rate fell to 82%, and the total complication rate rose to 15% in kidneys with nondilated collecting systems. Contrast-enhanced ultrasonography (CEUS) has been used in PCNL techniques to address this issue. Methods: We did this meta-analysis following the preferred reporting criteria for systematic reviews and meta-analysis to combine the data of published studies to compare the CEUS-guided PCNL and the standard US-guided PCNL (PRISMA). For relevant literature, we searched PubMed, Embase, Web of Science, CKNI, and the Cochrane Library. The final inclusion date for this meta-analysis was May 1, 2022, and three randomized controlled trials (RCTs) were finally included. RevMan V5.4.1 was used in this work. Standard mean difference (SMD) with a 95% confidence interval (CI) was utilized as the major estimate in the synthesis of continuous data, while odds ratio (OR) with a 95% CI was synthesized as the main estimate in the synthesis of discontinuous data. Results: We found that compared with traditional US-guided PCNL, CEUS-guided PCNL could offer more benefits in terms of single-needle success rate (OR: 3.02, 95% CI: 1.62 to 5.61, p = 0.0005), shorter puncture time (SMD: −1.33, 95% CI: −2.06 to −0.60, p = 0.0004), shorter hospital stays (SMD: −0.37, 95% CI: −0.60 to −0.13, p = 0.002), and a better stone clearance rate (OR: 2.32, 95% CI: 1.15 to 4.68. p = 0.02). Although the PCNL complication rate after surgery was not significantly reduced by the CEUS technique (overall complication: OR = 0.70, 95% CI: 0.37 to 1.30, p = 0.25. Grade 1/2 complication: OR = 0.79, 95% CI: 0.41 to 1.53, p = 0.48; Grade 3/4 complication: OR = 0.44, 95% CI: 0.10 to 1.98, p = 0.28), it could reduce hemoglobin dropping compared with conventional US-guided PCNL (SMD: −0.82, 95% CI: −1.06 to −0.58, p < 0.001). Conclusion: The CEUS-guided PCNL technique is superior to the US-guided PCNL, according to almost all synthesized data. Additional randomized studies are still required. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Acupuncture and combination therapy in the treatment of postpartum depression:a meta-analysis
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Jie Shen, Jin Xi, Jing-yu Liu, Youbing Xia, Yan Pan, and Jie Cheng
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Postpartum depression ,medicine.medical_specialty ,Combination therapy ,business.industry ,Meta-analysis ,Internal medicine ,Acupuncture ,Medicine ,business ,medicine.disease - Published
- 2021
7. Traditional Chinese medicine based on Zheng differentiation versus angiotensin receptor blocker/angiotensin-converting enzyme antagonist in efficacy of treating diabetic kidney disease: A meta-analysis of randomized clinical trials
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Hua Zhang, Shi-Dong Wang, Jin-Xi Zhao, Fan Shao, Chuan-Jiang Liu, Qing Gong, Tao Yang, Hong Yue, Yong-Hua Xiao, Qiang Fu, and Wei-Jun Huang
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medicine.medical_specialty ,Angiotensin receptor ,lcsh:R5-920 ,biology ,business.industry ,Urinary system ,Urology ,Renal function ,Angiotensin-converting enzyme ,Traditional Chinese medicine ,Cochrane Library ,diabetic kidney disease ,angiotensin-converting enzyme inhibitors ,meta-analysis ,traditional Chinese medicine ,Complementary and alternative medicine ,Meta-analysis ,medicine ,biology.protein ,business ,lcsh:Medicine (General) ,Glomerular hyperfiltration ,Angiotensin receptor antagonists - Abstract
Objective: To compare the efficacy of traditional Chinese medicine (TCM) based on Zheng differentiation with angiotensin receptor blocker/angiotensin-converting enzyme inhibitor (ARB/ACEI) in treating diabetic kidney disease (DKD) from the aspects of decreasing urinary microalbumin, declining 24-h urinary protein, reducing endpoint events, and renal function protection. Methods: The Chinese Biomedical Literature Database (CBM), the Chinese Academy of Sciences database (CNKI), the VIP Chinese journal database, Wanfang DATA, Medline database, Cochrane library, excerpt medical database (Embase), and Web of science were used for literature searching. The reviewer manager 5.3 software was utilized to analyze the data. Results: Twenty-four studies including 1956 participants were involved in this review. Results showed that TCM had a better effect (mean difference [MD], −23.20, 95% confidence interval [CI], −30.60 to −15.79, P < 0.00001) than ARB/ACEI on lowering urinary albumin excretion rate (UAER) and urine albumin-to-creatinine ratio (MD −4.56 mg/mmol, 95% CI, −5.76 to −3.36, P < 0.00001). Moreover, the advantage of decreasing UAER was greater as the follow-up period become longer (P = 0.04). TCM also had a better effect in 24-h urinal protein, decreasing 0.36 g/24 h (95% CI, −0.45 to −0.27, P < 0.00001) more than the control in shorter follow-up period (ranged from 12 to 24 weeks) subgroup but only 0.08 g/24 h (95% CI, −0.13 to −0.03, P = 0.0006) in the longer follow-up period (>24 weeks) subgroup. TCM worked as well as ACEI/ARB in reducing endpoint events (relative risk, 0.67, 95% CI, 0.20–2.224, P = 0.51) and decreasing urinary albumin concentration (UAC) (MD, −16.50, 95% CI, −46.28–13.28, P = 0.28). As for protecting renal function, TCM had an equal effect to AECI/ARB in improving creatinine clearance ratio (MD, −3.30, 95% CI, −6.66–0.03, P = 0.05) or estimated glomerular filtration rate (MD, 1.00, 95% CI, −0.59–2.58, P = 0.22). However, TCM had a better effect in releasing the glomerular hyperfiltration state (MD, −9.64, 95% CI, −14.45 to −4.84, P < 0.0001). Conclusions: TCM based on Zheng differentiation can work as well as ACEI/ARB in treating DKD and even better in decreasing urinary microalbumin and releasing glomerular hyperfiltration. It is a good alternative treatment of DKD.
- Published
- 2019
8. Qingre Yiqi Method along with Oral Hypoglycemic Drugs in Treating Adults with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
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Jin-Xi Zhao, Esther Aijia Shen, Shi-Dong Wang, Yong-Hua Xiao, Jiayue Li, Wei-Jun Huang, Zhuang Li, Qiang Fu, Guanxun Su, Yu Chen, Hua Zhang, Tao Yang, Yaofu Zhang, and Li Jiang
- Subjects
medicine.medical_specialty ,Article Subject ,business.industry ,Standard treatment ,Type 2 Diabetes Mellitus ,Blood sugar ,Subgroup analysis ,Traditional Chinese medicine ,Cochrane Library ,Gastroenterology ,law.invention ,Other systems of medicine ,Complementary and alternative medicine ,Randomized controlled trial ,law ,Meta-analysis ,Internal medicine ,Medicine ,business ,RZ201-999 ,Research Article - Abstract
Objective. To evaluate the efficacy of the Qingre Yiqi method in the treatment of type 2 diabetes mellitus (T2DM) with meta-analysis. Method. The randomized controlled trials (RCTs) of the Qingre Yiqi method in the treatment of T2DM in the PubMed, Medline, EMBase, Cochrane Library, Web of Science, Weipu Journal, China Knowledge Network (CNKI), and Wanfang database were conducted. Three reviewers independently conducted the screening, extracted the data, and assessed methodological quality. Data analysis was performed using Rev Man 5.3 software for statistical analysis. Results. A total of 15 RCTs, including 1440 patients, were included. The results showed that compared with oral hypoglycemic drugs alone, the add-on treatment of the Qingre Yiqi method could significantly improve Chinese medicine syndrome (OR (95%CI) = 3.66 [2.47,5.42], P < 0.00001 ) and lower the level of HbA1c (MD (95%CI) = −0.68 [0.91, −0.45], P < 0.00001 ), triglyceride (TG) (MD (95%CI) = −0.38 [−0.58,-0.17], P = 0.0004 ), low-density lipoprotein cholesterol (LDL-C) (MD (95%CI) = −0.25 [−0.37, −0.13], P < 0.0001 ), and total cholesterol(TC) (MD(95%CI) = −0.40[−0.67, −0.13], P = 0.003 ). In terms of fasting blood glucose (FBG) and postprandial blood sugar (PBG), subgroup analysis showed that the baseline of FBG and the number of combined oral hypoglycemic drugs of PBG were the major sources of heterogeneity. Conclusion. Compared with the standard treatment, the Qingre Yiqi method along with oral hypoglycemic drugs showed the more beneficial effects for T2DM on improving TCM syndromes and reducing the blood glucose and partial lipid parameter.
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- 2021
9. Is short-term therapy really sufficient to eradicate Helicobacter pylori infection?
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Zhou, Ning, Chen, Wei-xing, Zhang, Wei, Li, Lan, Jin, Xi, and Li, You-ming
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- 2010
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10. Uric Acid and Cognitive Impairment in Patients with Acute Ischemic Stroke: A Meta-Analysis.
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Yan, Xue, Ren, Zhong, Wen, Quan, Jin, Xi, Wang, Ying, and Zhang, Weimin
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URIC acid ,STROKE patients ,META-analysis ,COGNITION disorders - Abstract
Serum uric acid (UA) has been suggested to be correlated with outcomes after stroke. We performed a meta-analysis to evaluate the association between serum UA and post-stroke cognitive impairment (PSCI) in patients with acute ischemic stroke (AIS). Relevant observational studies were identified by search of electronic databases including PubMed, Embase, and Web of Science. A randomized-effect model incorporating the possible between-study heterogeneity was used to pool the results. Overall, eleven studies with 4246 patients of AIS were included, 2073 (48.8%) of them had PSCI. Pooled results showed that patients with PSCI had significantly higher level of serum UA as compared to those without PSCI (mean difference: 35.70 μmol/l, 95% confidence interval (CI): 8.36 to 63.01, p=0.01; I2=95%). Subgroup analysis showed significant higher level of serum UA in patients with PSCI evaluated during follow-up of 3 months to 3 years, but not for those evaluated during hospitalization (p for subgroup difference=0.01). In addition, results of meta-analysis also showed that compared to patients with lower serum UA, AIS patients with higher serum UA had increased risk of PSCI (odds ratio: 1.33, 95% CI: 1.02 to 1.73, p=0.04; I2=72%). Higher level of serum UA after disease onset may be a marker of increased risk of PSCI in patients with AIS. Although these findings need to be validated in large-scale prospective studies, the possible mechanisms underlying the association between UA and PSCI should be also investigated. [ABSTRACT FROM AUTHOR]
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- 2022
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11. The Impact of Diabetes on the Prognosis of Upper Tract Urothelial Carcinoma After Radical Nephroureterectomy: A Systematic Review and Meta-Analysis.
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Gao, Xiaoshuai, Zhou, Liang, Ai, Jianzhong, Wang, Wei, Di, Xingpeng, Peng, Liao, Liao, Banghua, Jin, Xi, Li, Hong, and Wang, Kunjie
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TRANSITIONAL cell carcinoma ,SURVIVAL rate ,OVERALL survival ,DIABETES ,PROGNOSIS ,BLADDER cancer - Abstract
Background: Studies have reported that diabetes is related to the prognosis of upper tract urothelial carcinoma (UTUC) after radical nephroureterectomy (RNU), but this conclusion is still controversial. Here, we performed a meta-analysis to comprehensively explore the association between diabetes and UTUC prognosis. Methods: In November 2020, we searched PubMed, Web of science and the Cochrane Library to find relevant studies that evaluated the effect of diabetes on the prognosis of UTUC. The Newcastle Ottawa Scale was used to assess the quality of the literature. Review Manager 5.3 was used to pool cancer-specific survival (CSS), overall survival (OS), recurrence-free survival (RFS) and intravesical recurrence (IVR). Results: A total of 10 studies with 11,303 patients were included in this meta-analysis. Our pooled results showed that diabetes did not affect the survival outcome of UTUC, including CSS (HR: 1.33, 95% CI: 0.89-1.98; P = 0.16), OS (HR: 1.18, 95% CI: 0.77-1.80; P = 0.45) and RFS (HR: 1.37, 95% CI: 0.91-2.05; P = 0.13). However, diabetes increased the risk of IVR of UTUC patients (HR: 1.26, 95% CI: 1.11-1.43; P = 0.0004). Conclusion: Although diabetes has no significant impact on the survival outcomes of UTUC after RNU, it increases the risk of IVR. Therefore, special attention should be paid to monitoring the IVR for UTUC patients with diabetes and the necessity of appropriate intravesical adjuvant treatment when needed. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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12. Efficacy and Safety of External Physical Vibration Lithecbole After Extracorporeal Shock Wave Lithotripsy or Retrograde Intrarenal Surgery for Urinary Stone: A Systematic Review and Meta-analysis.
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Yuan, Chi, Jian, Zhongyu, Jin, Xi, Ma, Yucheng, Li, Hong, and Wang, Kunjie
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EXTRACORPOREAL shock wave lithotripsy ,URINARY calculi ,WHOLE-body vibration ,KIDNEY pelvis ,KIDNEY stones ,SURGERY - Abstract
Introduction: The current study evaluated the efficacy and safety of external physical vibration lithecbole (EPVL) after extracorporeal shock wave lithotripsy (SWL) or retrograde intrarenal surgery (RIRS) for urolithiasis. Methods: Publicized literature was systematically searched from EMBASE, Cochrane Library, PubMed, ScienceDirect, ClinicalTrials.gov, and Web of Science up to February 2020. Fixed-effects or random-effects model was chosen in risk ratio (RR) calculation according to heterogeneity. Quality of evidence was estimated under the guidance of Cochrane handbook. Stone expulsion rate, stone-free rates (SFRs), and complication rates were set as end points. Results: Six randomized controlled trials, including 853 patients, were eligible for analysis. EPVL significantly increased SFR within 3 weeks (RR = 1.17, 95% CI: 1.06–1.29, P = 0.001) and above 3 weeks (RR = 1.19, 95% CI: 1.03–1.37, P = 0.02) after SWL. EPVL also improved SFR within 3 weeks (RR = 1.84, 95% CI: 1.35–2.49, P < 0.0001) and above 3 weeks (RR = 1.53, 95% CI: 1.33–1.77, P < 0.00001) after RIRS. Besides, EPVL can significantly increase SFRs for stones in renal pelvis, lower calix, and multiple locations (all P-value <0.05). Although the overall complication rate was not significantly higher in EPVL + RIRS group, it was found to be 1.38 times higher in EPVL+SWL group (RR = 1.38, 95% CI: 1.06–1.79, P = 0.02), especially the incidence of flank pain (RR = 3.11, 95% CI: 1.02–9.46, P = 0.05). Conclusions: EPVL is effective and safe with high SFRs (especially in renal pelvis, lower calix, and multiple locations) after SWL or RIRS and lower overall complication rate after RIRS in patients with urolithiasis. However, the overall complication rate (especially the incidence of flank pain) was higher after EPVL + SWL. [ABSTRACT FROM AUTHOR]
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- 2021
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13. Regional vs General Anesthesia for Retrograde Intrarenal Surgery: A Systematic Review and Meta-Analysis.
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Wang, Wei, Gao, XiaoShuai, Ma, Yucheng, Di, Xingpeng, Xiao, Kaiwen, Zhou, Liang, Jin, Xi, Li, Hong, and Wang, Kunjie
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GENERAL anesthesia ,CONDUCTION anesthesia ,CLINICAL trial registries ,VISUAL analog scale ,PATIENT selection ,ODDS ratio - Abstract
Purpose: To determine the effectiveness and safety of retrograde intrarenal surgery (RIRS) under regional anesthesia (RA) vs general anesthesia (GA). Methods: In February 2020, a comprehensive search of PubMed, EMBASE, Web of Science, Cochrane Library, ClinicalTrials.gov, and WHO International Clinical Trials Registry was performed to find eligible studies comparing outcomes of GA and RA during RIRS procedure. Result parameters, including stone-free rate (SFR), operation time, postoperative length of stay, postoperative first-day visual analog scale (VAS) score, and complication rates were assessed using RevMan 5.3. Results: Six studies (five randomized controlled trials and one retrospective study) with 1747 individuals were included. Pooled results revealed no statistical difference exist concerning SFR (odds ratio [OR] = 1.07, p = 0.63), postoperative length of stay (weighted mean difference [MD] = 0.08, p = 0.54), postoperative first-day VAS score (MD = −0.10, p = 0.23), and complication rates (OR = 0.91, p = 0.46). However, the RA group had shorter operation time (MD = −5.41, p < 0.00001) compared with GA group. Conclusion: The present study showed that RA demonstrated shorter operation time than GA, and was similar to GA regarding SFR, postoperative length of stay, postoperative first-day VAS score, and complication rates. We considered that RA might be a better alternative with prudent patient selection. [ABSTRACT FROM AUTHOR]
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- 2020
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14. Tumor M2-pyruvate kinase in stool as a biomarker for diagnosis of colorectal cancer: A meta-analysis
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Jin-Xi Huang, Yi Zhou, Chenghu Wang, Xie-Fu Zhang, Zhan-dong Zhang, and Weiwei Yuan
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Oncology ,medicine.medical_specialty ,diagnosis ,Colorectal cancer ,Pyruvate Kinase ,colorectal cancer ,Bioinformatics ,Sensitivity and Specificity ,lcsh:RC254-282 ,Likelihood ratios in diagnostic testing ,Internal medicine ,Biomarkers, Tumor ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Receiver operating characteristic ,business.industry ,Case-control study ,Biomarker ,General Medicine ,Publication bias ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,medicine.disease ,tumor M2-pyruvate kinase ,Confidence interval ,meta-analysis ,ROC Curve ,Case-Control Studies ,Meta-analysis ,Biomarker (medicine) ,Colorectal Neoplasms ,business ,Software - Abstract
Objective: The aim of this meta-analysis was to evaluate the diagnosis value of tumor M2-pyruvate kinase (M2-PK) in stool as a biomarker for diagnosis of colorectal cancer. Materials and Methods: By searching the databases of Cochrane Library, PubMed, China national knowledge Information and Wanfang, the diagnosis study related to tumor M2-PK in stool as a biomarker for diagnosis of colorectal cancer were screened and included in this study. The pooled sensitivity, specificity, positive likelihood ratio (+LR), negative likelihood ratio (−LR) and the receiver operating characteristic curve (ROC) were calculated by stata 11.0 software. Results: According to the including criteria, 14 trials including 1990 subjects were finally included in this meta-analysis. The pooled diagnosis sensitivity, specificity, +LR, −LR and area under curve were 0.78 (95% confidence interval [CI]: 0.74-0.81), 0.77 (95% CI: 0.76-0.79), 4.38 (95% CI: 3.27-5.88), 0.28 (95% CI: 0.23-0.34) and 0.86 (95% CI: 0.834-0.89). No statistical publication bias was found in this study. Conclusion: Tumor M2-PK in stool can be a useful biomarker in the diagnosis of colorectal cancer with relative high sensitivity and specificity.
- Published
- 2014
15. MicroRNA-146a rs2910164 G/C polymorphism and gastrointestinal cancer susceptibility: A meta-analysis based on East Asian population.
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Bei-Bei Chen, Xin-Guang Cao, Xiao-Bing Chen, Yi-Jie Ma, Wen-Ying Deng, Ning Li, Jin-Xi Huang, Su-Xia Luo, and Er-Jiang Zhao
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GASTROINTESTINAL cancer ,META-analysis ,MICRORNA ,GENETIC models ,GENOTYPES ,GENETICS - Abstract
Objective: The relationship between microRNA (miR-146a) rs2910164G/C polymorphism and gastrointestinal cancer susceptibility is not consistent with each other of the published articles. The aim of this meta-analysis was to acquire a more precise effect of the association between the miR-146a rs2910164 G/C polymorphism and gastrointestinal cancer. Materials and Methods: Through searching of the MedLine, Embase, China National Knowledge Infrastructure, and Wanfang databases. Case-control or cohort studies about the relationship between miR-146a rs2910164 G/C polymorphism and gastrointestinal cancer susceptibility were screened and included in this meta-analysis. Quantitative data synthesis was conducted for the associations of miR-146a rs2910164 G/C polymorphism and gastrointestinal cancer risk by statistical software STATA-11.0. Results: Ten studies including 6473 gastrointestinal cancer patients and 7923 controls were identified and included in this meta-analysis. For recessive genetic model (CC vs. CG + GG), people with CG or GG is associated with the susceptibility of gastrointestinal cancer compared with genotype of CC (R = 0.73, 5% confidence interval [CI]: 0.55-0.97, [P= 0.03]); But for dominant model (CC + CG vs. GG) and homozygous model (CC vs. GG), no association of the miR-146a rs2910164G/C polymorphism and gastrointestinal cancer susceptibility were found (dominant: Odds ratio [OR] =0.94, 95% CI: 0.82-1.03, [P= 0.37]; homozygous: OR = 0.85, 95% CI: 0.71-1.03, [P= 0.10]). Sub-group analysis, for homozygous model, people with GG genotype had increased risk of developing colorectal cancer (OR = 0.77, 95% CI: 0.6 4-0.93, [P= 0.008]). Conclusion: No significant association between miR-146a rs2910164G/C polymorphism and gastrointestinal cancer susceptibility was found in this meta-analysis. But for homozygous model, people with GG genotype may have increased risk of developing colorectal cancer. [ABSTRACT FROM AUTHOR]
- Published
- 2014
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16. Does combined lithotripter show superior stone-success rate than ultrasonic or pneumatic device alone during percutaneous nephrolithotrotomy? A meta-analysis.
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Lin, Lede, Zhou, Liang, Xiao, Kaiwen, Jin, Xi, Jian, Zhongyu, Liu, Yu, Li, Hong, and Wang, Kunjie
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META-analysis ,KIDNEY stones ,SYSTEMATIC reviews ,TREATMENT effectiveness ,LITHOTRIPSY ,ULTRASONICS ,LONGITUDINAL method - Abstract
Objectives: To compare the stone clearance rate and stone-success rate among lithotripter with ultrasonic lithotripter alone, pneumatic lithotripter alone and combined mechanisms.Methods: Up till 2021 May, we conducted a literature search among several widely used database around the world, including Pubmed, Embase (Ovid Version), Medline (Ovid Version) and Cochrane Central Register of Controlled Trials. Only English literature was considered. Pediatric patients were excluded. Reviews and protocols without any published data were excluded. Conference abstracts and articles with unrelated contents were also excluded.Results: Fifteen articles were included in our final meta-analysis, with 9 RCTs and 6 cohort studies. In Lithoclast combined with ultrasonic device vs pneumatic device subgroup, overall stone-success rate yielded insignificant difference. As for subgroup of Shock Pulse vs pneumatic device, pooled analysis yielded a higher 1-month stone-success rate for Shock Pulse (RR = 1.10, 95% CI: 1.01-1.19). In Lithoclast combined with ultrasonic device vs ultrasonic device subgroup and Cyberwand vs ultrasonic device subgroup, both overall stone-success rate did not differ from one another. We found Lithoclast with ultrasonic device was more efficient in stone clearance rate than pneumatic device (mean difference = 8.23, 95% CI: 4.99-11.47). The same situation was applied to the comparison between Lithoclast with ultrasonic device and ultrasonic device (mean difference = 13.02, 95% CI: 4.57-21.46).Conclusions: Combined lithotripter was more efficient in clearing stones than pneumatic or ultrasonic device alone. However, when it came to stone-success rate, no obvious superiority was seen in combined one. [ABSTRACT FROM AUTHOR]- Published
- 2022
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17. Meta-analysis for evaluating the accuracy of endoscopy with narrow band imaging in detecting colorectal adenomas.
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Jin, Xi-Feng, Chai, Tong-Hai, Shi, Jun-Wen, Yang, Xiu-Cheng, and Sun, Qing-Yan
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COLONOSCOPY , *COLON cancer diagnosis , *MEDICAL imaging systems , *ACCURACY , *META-analysis - Abstract
Background and Aim: The aim of this study was to determine whether the use of the narrow band imaging (NBI) system could enhance the accuracy of adenoma detection during an endoscopic examination of the colon and rectum. Methods: MEDLINE, EMBASE, and the Cochrane Library databases were searched along with a hand search of abstracts from relevant conferences up to June 2011. The rates of adenoma and flat adenoma detection, and withdrawal time were analyzed using Review Manager 4.2. Results: A total of 3049 subjects in eight trials were included. Meta-analysis revealed that there was no statistically significant difference in the rates of adenoma detection between the NBI group and the white light colonoscopy group (pooled relative risk [RR]: 1.09, 95% confidence interval [CI]: 1.00-1.19, P = 0.05). However, after exclusion of high-definition television modalities, the rate of adenoma detection by NBI was significantly higher than that by white light, particularly for patients with one adenoma (pooled RR 1.36, 95%CI 1.07-1.71, P = 0.02). Endoscopy with the NBI system significantly increased the rate of flat adenoma detection (pooled RR 1.96, 95%CI 1.09-3.52, P = 0.02). However, endoscopy with NBI had longer withdrawal time than that with white light (pooled weighted mean difference: 0.90, 95%CI: 0.38-1.42, P = 0.0006). Conclusions: Endoscopy with NBI seems to improve the detection of flat adenomas, particularly with high-definition technology, but prolongs the withdrawal time. These results indicate that endoscopy routinely using the NBI system for the surveillance of adenomas may be recommended after the technique is further modified. [ABSTRACT FROM AUTHOR]
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- 2012
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18. Glyceryl Trinitrate for Prevention of Post-ERCP Pancreatitis and Improve the Rate of Cannulation: A Meta-Analysis of Prospective, Randomized, Controlled Trials.
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Ding, Jiexia, Jin, Xi, Pan, Yue, Liu, Shan, and Li, Youming
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NITROGLYCERIN , *ENDOSCOPIC retrograde cholangiopancreatography , *PANCREATITIS , *CATHETERIZATION , *META-analysis , *LONGITUDINAL method , *RANDOMIZED controlled trials , *PANCREATITIS diagnosis , *PREVENTION - Abstract
Background:Acute pancreatitis is the most common complication of diagnostic and therapeutic endoscopic retrograde cholangiopancreatography (ERCP). Several clinical trials used glyceryl trinitrate (GTN) to prevent the incidence of post-ERCP pancreatitis (PEP). However, the results were still controversial. Objective:To conduct a meta-analysis of published, full-length, randomized controlled trials evaluating the effect of prophylactic GTN on the prevention of PEP, improve the rate of cannulation and the prevention of hyperamylasemia. Methods:Literature searches were conducted using PubMed, EMBASE, The Cochrane Library and Web of Knowledge databases, using keywords "post-ERCP" and "pancreatitis" and limited in randomized controlled trials. Results:Twelve RCTs involving 2649 patients were included. Eleven RCTs compared GTN with placebo for PEP prevention. Meta-analysis showed the overall incidence of PEP was significantly reduced by GTN treatment (RR 0.67; 95% CI, 0.52-0.87). Nevertheless, GTN administration did not decrease the incidence of moderate to severe PEP (RR 0.70; 95% CI, 0.42-1.15). Subgroup analyses revealed that GTN administered by sublingual was more effective than transdermal and topical in reducing the incidence of PEP. Besides, the prophylactic effect of GTN was far more obvious in the group of high PEP incidence than in the group of low PEP incidence. Additionally, the incidence of hyperamylasemia was significantly reduced by GTN treatment (RR 0.69; 95% CI, 0.54-0.90). No differences of the successful cannulation rate of bile ducts (RR 1.03; 95% CI, 0.99-1.06) attributable to GTN were observed. Conclusion:Prophylactic use of GTN reduced the overall incidence of PEP and hyperamylasemia. However, GTN was not helpful for the severity of PEP and the rate of cannulation. [ABSTRACT FROM AUTHOR]
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- 2013
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19. Association between insomnia and frailty in older population: A meta‐analytic evaluation of the observational studies.
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Wen, Quan, Yan, Xue, Ren, Zhong, Wang, Bo, Liu, Yuqiu, and Jin, Xi
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FRAILTY , *SLEEP quality , *INSOMNIA , *SCIENTIFIC observation , *OLDER people , *STUDENT adjustment - Abstract
Introduction: Poor sleep quality has been suggested as a risk factor of frailty. However, previous studies that evaluated the association between insomnia and frailty in older population showed inconsistent results. We performed a meta‐analysis to comprehensively evaluate the association. Methods: Observational studies related to the aim of the meta‐analysis were identified by search of PubMed, Embase, and Web of Science databases. A random‐effect model incorporating the potential between‐study heterogeneity was used to pool the results. Results: Twelve studies including 16,895 old people contributed to the meta‐analysis. Pooled results suggested a significant association between insomnia and frailty in the older population (odds ratio [OR]: 1.95, 95% confidence interval [CI]: 1.52–2.41, p <.001; I2 = 80%). Subgroup analyses showed consistent association between different symptoms of insomnia and frailty, including difficulty in falling asleep (OR: 1.45), difficulty in maintaining sleep (OR: 1.23), early morning awakening (OR: 1.21), and non‐restorative sleep (OR: 1.84, p for subgroup difference =.15). Results were also consistent for subgroup analyses according to the study country, sample size, cutoffs of age for defining the older population, proportions of men, diagnostic criteria for frailty, adjustment of depression, and scores of study quality (p for subgroup difference all >.05). However, a stronger association was observed for insomnia detected with the Athens Insomnia Scale (OR: 2.92) than that with Pittsburgh Sleep Quality Index (OR: 1.30) or self‐reporting (OR: 1.60, p for subgroup difference =.002). Conclusion: Insomnia is independently associated with frailty in the older population. [ABSTRACT FROM AUTHOR]
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- 2023
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20. Depression increases the risk of kidney stone: Results from the National Health and Nutrition Examination Survey 2007-2018 and Mendelian randomization analysis.
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Wang, Menghua, Jian, Zhongyu, Ma, Yucheng, Jin, Xi, Li, Hong, and Wang, Kunjie
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HEALTH & Nutrition Examination Survey , *KIDNEY stones , *DISEASE risk factors , *GENOME-wide association studies , *RESEARCH , *SEQUENCE analysis , *META-analysis , *GENETIC polymorphisms , *EVALUATION research , *SURVEYS , *COMPARATIVE studies , *MENTAL depression , *QUESTIONNAIRES , *LONGITUDINAL method - Abstract
Background: To investigate whether depression increases the kidney stone risk.Methods: First, we performed an observational study in the National Health and Nutrition Examination Survey (NHANES) 2007-2018. Depression severity was evaluated using the Patient Health Questionnaire-9 (PHQ-9) and classified into no, mild, moderate, and severe depression groups. Multivariable-adjusted logistic regression was used to assess the correlation between depression severity and kidney stone risk. Second, Mendelian randomization (MR) was applied to decrease the bias and avoid the reverse causality in the observational study. Genetic instruments were obtained from a large genome-wide association study (GWAS) meta-analysis of depression involved 246,363 cases and 561,190 controls. We obtained summary data for kidney stone from another large GWAS, which integrates data from 6536 stone formers and 388,508 controls. Inverse variance weighted (IVW) was the primary analytical method.Results: In the observational study, a total of 24,892 individuals were enrolled. Individuals with moderate (OR 1.38, 95 % CI 1.05-1.83, P = 0.022) and severe (OR 1.56, 95 % CI 1.02-2.40, P = 0.040) depression had a higher risk of kidney stone (P for trend = 0.006) compared with the control. For the MR, results also showed that genetically predicted depression was causally associated with a higher risk of kidney stone disease (OR 1.26, 95 % CI 1.04-1.53, P = 0.017) in IVW.Conclusions: Depression might be associated with kidney stone risk. This finding is needed to be verified in further prospective cohort studies with a large sample size and enough follow-up time. [ABSTRACT FROM AUTHOR]- Published
- 2022
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21. Traditional Chinese medicine based on Zheng differentiation versus angiotensin receptor blocker/angiotensin-converting enzyme antagonist in efficacy of treating diabetic kidney disease: A meta-analysis of randomized clinical trials
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Wei-Jun Huang, Tao Yang, Chuan-Jiang Liu, Yong-Hua Xiao, Qiang Fu, Qing Gong, Hua Zhang, Fan Shao, Hong Yue, Shi-Dong Wang, and Jin-Xi Zhao
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Angiotensin receptor antagonists ,angiotensin-converting enzyme inhibitors ,diabetic kidney disease ,meta-analysis ,traditional Chinese medicine ,Medicine (General) ,R5-920 - Abstract
Objective: To compare the efficacy of traditional Chinese medicine (TCM) based on Zheng differentiation with angiotensin receptor blocker/angiotensin-converting enzyme inhibitor (ARB/ACEI) in treating diabetic kidney disease (DKD) from the aspects of decreasing urinary microalbumin, declining 24-h urinary protein, reducing endpoint events, and renal function protection. Methods: The Chinese Biomedical Literature Database (CBM), the Chinese Academy of Sciences database (CNKI), the VIP Chinese journal database, Wanfang DATA, Medline database, Cochrane library, excerpt medical database (Embase), and Web of science were used for literature searching. The reviewer manager 5.3 software was utilized to analyze the data. Results: Twenty-four studies including 1956 participants were involved in this review. Results showed that TCM had a better effect (mean difference [MD], −23.20, 95% confidence interval [CI], −30.60 to −15.79, P < 0.00001) than ARB/ACEI on lowering urinary albumin excretion rate (UAER) and urine albumin-to-creatinine ratio (MD −4.56 mg/mmol, 95% CI, −5.76 to −3.36, P < 0.00001). Moreover, the advantage of decreasing UAER was greater as the follow-up period become longer (P = 0.04). TCM also had a better effect in 24-h urinal protein, decreasing 0.36 g/24 h (95% CI, −0.45 to −0.27, P < 0.00001) more than the control in shorter follow-up period (ranged from 12 to 24 weeks) subgroup but only 0.08 g/24 h (95% CI, −0.13 to −0.03, P = 0.0006) in the longer follow-up period (>24 weeks) subgroup. TCM worked as well as ACEI/ARB in reducing endpoint events (relative risk, 0.67, 95% CI, 0.20–2.224, P = 0.51) and decreasing urinary albumin concentration (UAC) (MD, −16.50, 95% CI, −46.28–13.28, P = 0.28). As for protecting renal function, TCM had an equal effect to AECI/ARB in improving creatinine clearance ratio (MD, −3.30, 95% CI, −6.66–0.03, P = 0.05) or estimated glomerular filtration rate (MD, 1.00, 95% CI, −0.59–2.58, P = 0.22). However, TCM had a better effect in releasing the glomerular hyperfiltration state (MD, −9.64, 95% CI, −14.45 to −4.84, P < 0.0001). Conclusions: TCM based on Zheng differentiation can work as well as ACEI/ARB in treating DKD and even better in decreasing urinary microalbumin and releasing glomerular hyperfiltration. It is a good alternative treatment of DKD.
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- 2019
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