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4 results on '"Ghojoghi A"'

2. Non-albicans candidemia in cancer patients as an increasing health problem: A comprehensive review and meta-analysis

Author

Aynaz Ghojoghi, Maryam Erfaninejad, Ehsan Ahmadpour, Eisa Nazar, Aleksandra Barac, and Mahnaz Fatahinia

Subjects
candidemia, non-albicans candida, cancer, epidemiology, systematic review, meta-analysis, Arctic medicine. Tropical medicine, RC955-962
Abstract

Objective: To evaluate the prevalence of Candida species in cancer patients with candidemia around the world, and to identify related risk factors and their antifungal resistance, with an emphasis on non-albicans Candida species (NACs). Methods: The published papers related to the subject were systematically searched in databases of MEDLINE (including PubMed), Web of Science, Scopus, Science Direct, and Google Scholar between the 1st January 2000 and 21st April 2021. Results: Among the 4 546 records, 69 studies met the inclusion criteria. The pooled prevalence of NACs in cancer patients with candidemia was 62% (95% CI 58%-67%; I2=94.85%, P=0.00). Based on type of cancer, the pooled prevalence of NACs in hematologic and solid cancer patients were 68% (95% CI 65%- 70%) and 52% (95% CI 49%-54%), respectively. Among NACs, Candida (C.) parapsilosis was the most frequently isolated organism followed by C. tropicalis and C. glabrata. In addition, the therapeutic usage of antibiotics was found as the most common risk factor, accounting for 85% (95% CI 81%-89%) and central venous catheter accounting for 69% (95% CI 62%-77%). Conclusions: The incidence of Candida bloodstream infections among cancer patients is a growing concern, especially when the etiologic agents of candidemia tend to shift towards NACs.

Published
2022
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3. Toxoplasma gondii Infection in Marine Animal Species, as a Potential Source of Food Contamination: A Systematic Review and Meta-Analysis

Author

Ehsan Ahmadpour, Mohamad Taghi Rahimi, Altin Ghojoghi, Fatemeh Rezaei, Kareem Hatam-Nahavandi, Sónia M. R. Oliveira, Maria de Lourdes Pereira, Hamidreza Majidiani, Abolghasem Siyadatpanah, Samira Elhamirad, Wei Cong, and Abdol Sattar Pagheh

Subjects
Antibodies, Protozoan, Toxoplasma gondii, Food Contamination, Review, Meta-analysis, Toxoplasmosis, Animal, Seroepidemiologic Studies, Marine animals, Agglutination Tests, parasitic diseases, Systematic review, Animals, Parasitology, Toxoplasma, Toxoplasmosis, Otters
Abstract

Purpose Many marine animals are infected and susceptible to toxoplasmosis, which is considered as a potential transmission source of Toxoplasma gondii to other hosts, especially humans. The current systematic review and meta-analysis aimed to determine the prevalence of T. gondii infection among sea animal species worldwide and highlight the existing gaps. Methods Data collection was systematically done through searching databases, including PubMed, Science Direct, Google Scholar, Scopus, and Web of Science from 1997 to July 2020. Results Our search strategy resulted in the retrieval of 55 eligible studies reporting the prevalence of marine T. gondii infection. The highest prevalence belonged to mustelids (sea otter) with 54.8% (95% CI 34.21–74.57) and cetaceans (whale, dolphin, and porpoise) with 30.92% (95% CI 17.85–45.76). The microscopic agglutination test (MAT) with 41 records and indirect immunofluorescence assay (IFA) with 30 records were the most applied diagnostic techniques for T. gondii detection in marine species. Conclusions Our results indicated the geographic distribution and spectrum of infected marine species with T. gondii in different parts of the world. The spread of T. gondii among marine animals can affect the health of humans and other animals; in addition, it is possible that marine mammals act as sentinels of environmental contamination, especially the parasites by consuming water or prey species. Graphical Abstract Supplementary Information The online version contains supplementary material available at 10.1007/s11686-021-00507-z.

Published
2021

4. Non-albicans candidemia in cancer patients as an increasing health problem: A comprehensive review and meta-analysis.

Author

Ghojoghi, Aynaz, Erfaninejad, Maryam, Ahmadpour, Ehsan, Nazar, Eisa, Barac, Aleksandra, and Fatahinia, Mahnaz

Abstract

Objective: To evaluate the prevalence of Candida species in cancer patients with candidemia around the world, and to identify related risk factors and their antifungal resistance, with an emphasis on non-albicans Candida species (NACs). Methods: The published papers related to the subject were systematically searched in databases of MEDLINE (including PubMed), Web of Science, Scopus, Science Direct, and Google Scholar between the 1st January 2000 and 21st April 2021. Candida (C.) parapsilosis was the most frequently isolated organism followed by C. tropicalis and C. glabrata. In addition, the therapeutic usage of antibiotics was found as the most common risk factor, accounting for 85% (95% CI 81%-89%) and central venous catheter accounting for 69% (95% CI 62%-77%). Conclusions: The incidence of Candida bloodstream infections among cancer patients is a growing concern, especially when the etiologic agents of candidemia tend to shift towards NACs. [ABSTRACT FROM AUTHOR]

Published
2022
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