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Your search keyword '"Cioffi Squitieri N"' showing total 3 results
Start Over Author "Cioffi Squitieri N" Topic mesentery
3 results on '"Cioffi Squitieri N"'

2. Gastrointestinal stromal tumors (GIST): a proposal of a "CT-based predictive model of Miettinen index" in predicting the risk of malignancy.

Author

Mazzei, M. A., Cioffi Squitieri, N., Vindigni, C., Guerrini, S., Gentili, F., Sadotti, G., Mercuri, P., Righi, L., Lucii, G., Mazzei, F. G., Marrelli, D., and Volterrani, L.

Subjects
*GASTROINTESTINAL stromal tumors, *PREDICTION models, *RECEIVER operating characteristic curves, *MESENTERY, *CALCIFICATIONS of the breast, *TUMOR growth
Abstract

Purpose: To identify the predictors of malignancy on CT for the evaluation of gastrointestinal stromal tumors (GIST) by correlating CT findings with the mitotic index in order to propose a "CT-based predictive model of Miettinen index." Methods: One radiologist and one resident in radiology with 14- and 4-year experience in oncological field reviewed the CT findings of 42 patients by consensus, with respect to lesion site, size, contour, tumor growth pattern, enhancing pattern, degree of enhancement of tumor, percentage of tumor necrosis, mesenteric fat infiltration, ulceration, calcification, regional lymphadenopathy, direct invasion to adjacent organs, and distant metastasis. All parameters were correlated with the mitotic index evaluated at histopathological analysis following surgery. Normality of variables was evaluated using Shapiro–Wilk test. Pearson's correlation test was used to assess the interaction between variables. The diagnostic accuracy percentage of tumor necrosis was measured by receiver operating characteristic (ROC) analysis for detecting whether the number of mitosis per 50 high-power fields was > 5. Results: A significant statistical correlation was found between percentage of tumor necrosis and the mitotic index (p < 0.005), dimension, and location of the tumor. Conclusion: CT could be an accurate technique in the prediction of malignancy of GIST in a CT risk assessment system, based on the location of the tumor, its size, and the percentage of tumor necrosis. [ABSTRACT FROM AUTHOR]

Published
2020
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3. Reperfusion in non-occlusive mesenteric ischaemia (NOMI): effectiveness of CT in an emergency setting

Author

Nevada Cioffi Squitieri, Giusi Imbriaco, Carla Vindigni, Francesco Gentili, Maria Antonietta Mazzei, Daniela Berritto, Luca Volterrani, Roberto Grassi, Francesco Giuseppe Mazzei, Susanna Guerrini, Mazzei, Ma, Guerrini, S, Cioffi Squitieri, N, Vindigni, C, Imbriaco, G, Gentili, F, Berritto, D, Mazzei, Fg, Grassi, Roberto, and Volterrani, L.

Subjects
Male, medicine.medical_specialty, Autopsy, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Mesenteric Artery, Superior, medicine.artery, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Superior mesenteric artery, Emergency Radiology Special Feature, Mesentery, Aged, Retrospective Studies, Aged, 80 and over, medicine.diagnostic_test, business.industry, Retrospective cohort study, General Medicine, Middle Aged, SMA, medicine.disease, Endoscopy, medicine.anatomical_structure, Mesenteric ischemia, Mesenteric Ischemia, 030220 oncology & carcinogenesis, Angiography, Female, Radiology, Emergency Service, Hospital, Tomography, X-Ray Computed, business
Abstract

To investigate the CT features of reperfusion (presence/absence) in non-occlusive mesenteric ischaemia (NOMI) and their prognostic value in an emergency setting.A revision was undertaken of imaging from 20 patients (16 males/4 females) with a dismissal summary of NOMI. All patients had previously undergone a minimum of one multidetector CT examination, and consequently underwent surgery (n = 8), autopsy (n = 2), angiography (n = 1) or endoscopy (n = 9). An evaluation of the CT scans was conducted to determine vessels, mesentery, bowel and peritoneal cavity features. The superior mesenteric artery (SMA) average diameter of NOMI cases were compared with 30 controlled cases. Kappa, Kolmogorov-Smirnov (K-S) and Fisher's exact tests were used for statistical analysis.A mean SMA diameter significantly smaller than that of the controlled cases was found for patients with NOMI (K-S test: D = 0.75, p = 3.7 × 10-08). Fisher's exact tests showed a strong connection between the presence of reperfusion and mesenteric fat stranding (p = 0.026), bowel wall thickening (p = 3.2 × 10-05) and a high attenuation of the bowel wall on unenhanced CT images (p = 2.8 × 10-04). A reduction in mortality was significantly linked to the combination of normal mesenteric vessels and wall thickening (p = 0.034).Analysis of not only vessels findings but also mesentery and bowel CT features will support the identification of NOMI with or without a reperfusion event in an emergency setting. A strong correlation between some CT features and lower mortality exists.CT features of NOMI with or without reperfusion are demonstrated. Correctly assessing the presence of reperfusion in NOMI, may allow better management of these conditions in the emergency setting.

Published
2016
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