Search

Whether caffeine (CAF) increases fat metabolism remains debatable. Using systematic review coupled with meta-analysis, our aim was to determine effects of CAF on fat metabolism and the relevant factors moderating this effect. Electronic databases PubMed, SPORTDiscus, and Web of Science were searched using the following string: CAF AND (fat OR lipid) AND (metabolism OR oxidation). A meta-analytic approach aggregated data from 94 studies examining CAF's effect on fat metabolism assessed by different biomarkers. The overall effect size (ES) was 0.39 (95% confidence interval [CI] [0.30, 0.47], p <.001), indicating a small effect of CAF to increase fat metabolism; however, ES was significantly higher (p <.001) based on blood biomarkers (e.g., free fatty acids, glycerol) (ES = 0.55, 95% CI [0.43, 0.67]) versus expired gas analysis (respiratory exchange ratio, calculated fat oxidation) (ES = 0.26, 95% CI [0.16, 0.37]), although both were greater than zero. Fat metabolism increased to a greater extent (p =.02) during rest (ES = 0.51, 95% CI [0.41, 0.62]) versus exercise (ES = 0.35, 95% CI [0.26, 0.44]) across all studies, although ES was not different for studies reporting both conditions (ES = 0.49 and 0.44, respectively). There were no subgroup differences based on participants' fitness level, sex, or CAF dosage. CAF ingestion increases fat metabolism but is more consistent with blood biomarkers versus whole-body gas exchange measures. CAF has a small effect during rest across all studies, although similar to exercise when compared within the same study. CAF dosage did not moderate this effect. [ABSTRACT FROM AUTHOR]

Introduction Conflicting evidence exists on whether physical activity (PA) levels of humans have changed over the last quarter-century. The main objective of this study was to determine if there is evidence of time trends in PA, from cross-sectional studies that assessed PA at different time points using wearable devices (e.g. pedometers and accelerometers). A secondary objective was to quantify the rate of change in PA. Methods A systematic literature review was conducted of English-language studies indexed in PubMed, SPORTDiscus, and Web of Science (1960–2020) using search terms (time OR temporal OR secular) AND trends AND (steps per day OR pedometer OR accelerometer OR MVPA). Subsequently, a meta-analytic approach was used to aggregate data from multiple studies and to examine specific factors (i.e. sex, age-group, sex and age-group, and PA metric). Results Based on 16 peer-reviewed scientific studies conducted between 1995 and 2017, levels of ambulatory PA are trending downward in developed countries. Significant declines were seen in both males and females (P < 0.001) as well as in children (P = 0.020), adolescents (P < 0.001), and adults (P = 0.004). The average study duration was 9.4 yr (accelerometer studies, 5.3 yr; pedometer studies, 10.8 yr). For studies that assessed steps, the average change in PA was −1118 steps per day over the course of the study (P < 0.001), and adolescents had the greatest change in PA at −2278 steps per day (P < 0.001). Adolescents also had the steepest rate of change over time, expressed in steps per day per decade. Conclusions Evidence from studies conducted in eight developed nations over a 22-yr period indicates that PA levels have declined overall, especially in adolescents. This study emphasizes the need for continued research tracking time trends in PA using wearable devices. [ABSTRACT FROM AUTHOR]

The purpose of this study was to develop a compendium of wheelchair-related physical activities. To accomplish this, we conducted a systematic review of the published energy costs of activities performed by individuals who use wheelchairs. A total of 266 studies were identified by a literature search using relevant keywords. Inclusion criteria were studies utilizing individuals who routinely use a manual wheelchair, indirect calorimetry as the criterion measurement, energy expenditure expressed as METs or VO2, and physical activities typical of wheelchair users. Eleven studies met the inclusion criteria. A total of 63 different wheelchair activities were identified with energy expenditure values ranging from 0.8 to 12.5 kcal·kg-1·hr-1. The energy requirements for some activities differed between individuals who use wheelchairs and those who do not. The compendium of wheelchair-related activities can be used to enhance scoring of physical activity surveys and to promote the benefits of activity in this population. [ABSTRACT FROM AUTHOR]

Context: Carbohydrate (CHO) and caffeine (CAF) both improve endurance performance. Purpose: To determine by systematic literature review coupled with meta-analysis whether CAF ingested with CHO (CHO+CAF) improves endurance performance more than CHO alone. Methods: Databases were searched using the keywords caffeine, endurance, exercise, carbohydrate, and performance. Criteria for inclusion were studies that used human subjects performing an endurance-exercise performance task and included both a CHO and CHO+CAF condition. Effect sizes (ESs) were calculated as the standardized mean difference. Results: Twenty-one studies met the criteria for analysis. ESs for individual studies ranged from -0.08 (trivial effect favoring CHO) to 1.01 (large effect favoring CHO+CAF). The overall ES equaled 0.26 (95% CI 0.15-0.38, p < .001), indicating that CHO+CAF provides a small but significant performance benefit over CHO. ES was not significantly (p > .05) related to CAF dose, exercise duration, or performance-assessment method. To determine whether ES of CHO+CAF vs. CHO was different than CAF compared with water (placebo), a subgroup meta-analysis compared 36 CAF vs. placebo studies against the 21 CHO+CAF vs. CHO studies. The overall ES for the former group of studies (ES = 0.51, 95% CI 0.40-0.61) was nearly 2-fold greater than in CHO+CAF vs. CHO studies (p = .006). Conclusions: CHO+CAF ingestion provides a significant but small effect to improve endurance performance compared with CHO alone. However, the magnitude of the performance benefit that CAF provides is less when added to CHO than when added to placebo. [ABSTRACT FROM AUTHOR]