1. Long‐term weight loss maintenance with obesity pharmacotherapy: A retrospective cohort study
- Author
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Louis J. Aronne, Alan Wu, Alpana P. Shukla, Mohini Aras, and Beverly G. Tchang
- Subjects
Pediatrics ,medicine.medical_specialty ,Nutrition and Dietetics ,business.industry ,Endocrinology, Diabetes and Metabolism ,Retrospective cohort study ,Weight control ,medicine.disease ,Obesity ,Term (time) ,Pharmacotherapy ,Weight loss ,Weight maintenance ,Weight management ,Medicine ,medicine.symptom ,business - Abstract
To determine the association of anti-obesity medications (AOMs) with weight loss maintenance over 2 years.This is a retrospective observational cohort study of adults treated for obesity between 1 April 2014 and 1 April 2016 at a tertiary academic weight management center and who completed 2 years of follow-up. Main outcome measures were mean percent weight loss, percent of individuals who achieved clinically significant long-term weight loss (≥5% weight loss over 2 years), and long-term weight loss maintenance (achievement of ≥5% weight loss at 1 year and maintenance of the ≥5% reduction for the second year).Of the 1566 new patients, 421 completed 1- and 2-year follow-up appointments. Patients were mostly female and on average 51 years old; they weighed 100.1 kg and had a BMI of 35.8 kg/mLong-term weight loss maintenance was observed among adults with medically managed obesity who completed 2 years of follow-up.
- Published
- 2021