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Neonatal diarrhea leads to overall loss of not only electrolytes and water, but also decreases carbohydrates, lipids, and amino acids in calves. The mean fecal fat content was higher in calves with diarrhea than in healthy calves, and the mean caloric intake from milk was decreased by 31% in diarrheic calves compared with that in healthy calves. The negative energy balance continues during the diarrhea period. In addition, diarrheic calves fall into metabolic acidosis. Several studies have demonstrated that metabolic acidosis activates the catabolism of proteins and oxidation of branched-chain amino acids (BCAA) in muscle. If plasma amino acid profiles of diarrheic calves are similar with those in human with acidemia, more energy may be required for diarrheic calves with acidemia. However, intravenous nutrition for diarrheic calves with proteolysis-induced acidemia is poorly understood. The aim of this study was to investigate the relationship between acid-base status and plasma BCAA concentration in calves with diarrhea. This data may be useful for intravenous nutrition, especially with amino acid solutions, in calves with diarrhea., American Association of Bovine Practitioners Proceedings of the Annual Conference, 2017

Neonatal diarrhea remains the most common cause of death in beef and dairy calves. Intravenous (IV) fluid therapy is an important method for decreasing mortality associated with diarrhea in calves. Although Acetated Ringer's (AR) solution is superior for correcting moderate metabolic acidosis and circulation volume in calves with dehydration, it cannot improve the negative energy balance. Fluids using AR with 5% dextrose (ARD) may be useful for the treatment of calf diarrhea in order to prevent catabolism. The objectives of this study were to evaluate the effects of ARD on rehydration and metabolism restoration in calves with diarrhea., American Association of Bovine Practitioners Proceedings of the Annual Conference, 2016

Amino acid metabolism in cancer cells is significantly altered compared with that of normal cells. These changes are also reflected in the plasma amino acid profiles of patients with various types of inflammatory disease in human. Our hypothesis is that serum amino acid profiles of calves with mycoplasma Effecbronchopneumonia will be similar to those in human disease due to the inflammation and generalized catabolic state of these animals. The aim of this study was to investigate the relationships with serum amino acid profiles, total amino acids (TAA), branched amino acid:aromatic amino acid (BCAA/AAA) ratio, branched chain amino acid to tyrosine ratio (BTR) and serine to phosphorserine ratio (SPR) in calves with lung inflammation associated with mycoplasma bronchopneumonia. Receiver operative characteristic (ROC) curves was constructed to describe the performance of amino acid profiles in calves with mycoplasma bronchopneumonia. These data may be useful diagnostically and prognostically in calves with bronchopneumonia., American Association of Bovine Practitioners Proceedings of the Annual Conference, 2015