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Oral mucositis is a common and debilitating consequence of cancer patients undergoing antineoplastic treatment. There is no consensus on the most appropriate treatment for this condition. The best protocol to use should. consider each patient's specific needs and cost-effectiveness of treatment. Copaiba oil is a low-cost herbal medicine with scientifically proven anti-inflammatory, bactericidal, antitumor,and healing action.

SummaryOnline-available information has been considered an accessory tool to estimate epidemiology and collect data on diseases and population behavior patterns. This study aimed to explore the potential use of Google and YouTube relative search volume to predict social distancing index in Brazil during COVID-19 outbreak and verify the correlation between social distancing measures with the course of the epidemic. Data concerning the social distancing index, epidemiological data on COVID-19 in Brazil and the search engines trends for “Coronavirus” were retrieved from online databases. Multiple linear regression was performed and resulted in a statistically significant model evidencing that Google and YouTube relative search volumes are predictors of the social distancing index. The Spearman correlation test revealed a weak correlation between social distancing measures and the course of the COVID-19 epidemic. Health authorities can apply these data to define the proper timing and location for practicing appropriate risk communication strategies.

Opportunistic infections in oral cavity can cause serious complications in immunocompromised cancer patients, being quick and efficient treatments options essential. This article proposes to report two clinical cases of adolescent patients diagnosed with leukemia and who presented infectious conditions in the oral cavity, in which antimicrobial photodynamic therapy was used as a adjuvant therapy to abbreviate the course of oral lesions.

Oral cancer persists as a public health problem. Thus, mechanisms that ensure active involvement of the population must be created. Within this context, the Mouth Cancer Control Program of the University of Pernambuco (UPE) has been updating and training professionals in the prevention, and differential and early diagnosis of oral cancer since 1998 by performing educational, preventive, and diagnostic activities without interruptions. CAAE: 0201.0.097.000-08. From January 2002 to January 2017, 1400 students from UPE and 300 students from other educational institutions participated in the development of the activities. A total of 8600 professionals were trained in 63 cities in Pernambuco and 59,600 individuals participated in the educational/preventive activities designed to improve self-care, prevention, and the early detection of oral cancer. A total of 2984 individuals were examined during the training. Among the oral lesions identified and investigated by biopsy, 33% were potentially malignant lesions and 12% were malignant lesions (cancer). Health education is an excellent tool for the popularization and diffusion of technical–scientific knowledge, demystifying the disease and bringing its description closer to the population, thus permitting the identification of risk factors and the search for prevention and early detection. Brazil still faces some challenges, but education and guaranteed access to and greater effectiveness of health services will provide better conditions for the prevention, early detection, and reduction of disabilities and death since oral cancer can be prevented and cured when diagnosed at an early stage.

O Papiloma Escamoso oral é uma neoplasia benigna de origem epitelial, bastante comum, associado à infecção pelo Papiloma Vírus Humano (HPV). Clinicamente apresenta-se como nódulo exofítico, mole, indolor e geralmente pedunculado, com aspecto verrucoso/papilomatoso. Esse trabalho tem por objetivo relatar um caso de uma paciente com diagnóstico clínico e histopatológico de papiloma escamoso oral de grande dimensão, com focos de displasia epitelial moderada, localizado em mucosa jugal e face interna de lábios do lado direito. O tratamento inicialmente indicado foi a excisão cirúrgica e, posteriormente a excisão cirúrgica com reconstrução plástica, porém a paciente em decorrência de questões sociais, medo e ausência de apoio familiar, mesmo sabendo dos riscos de transformação maligna da lesão recusou o tratamento. Apesar da necessidade de tratamento a paciente possui autonomia para tomada de decisões e o direito à recusa de tratamento é reconhecido pelo Código Civil brasileiro como um dos direitos da personalidade. Respeitar a autonomia da paciente caracteriza um sistema de saúde humanizado e constitui um dos principais desafios enfrentados pelos profissionais de saúde.

Patient N.J.E., a 69-year-old black male liver recipient, complained of pain in the oral cavity. Clinical examination revealed ulcerated lesions on the dorsal surface of the tongue, right buccal mucosa, and lower right vestibule. In view of clinical findings and medical history, the diagnostic hypothesis suggested an oral infection. The culture was carried out with the purpose of microbiologic analysis (swab) along with incisional biopsy of tongue lesion, leading to a diagnosis of Actinomyces infection. The patient was treated with specific antimicrobials, oral topical solutions, and, as an adjuvant, antimicrobial photodynamic therapy (aPDT). aPDT consisted of daily application of the photosensitizer on the lesions, and after 5 minutes, the low-level light laser was applied in the visible red spectrum (660 nm) with fixed power of 100 mW and energy density of 6 J/cm². After 15 days, good clinical tissue recovery was observed; however, because of other systemic complications, the patient died.