Search

The CARe Burn Scales are a portfolio of burn-specific PROMs for people affected by burns, including a Child Form (for children &lt, 8 years (parent-proxy)), a Young Person Form (for young people aged 8–17 years), an Adult Form, and a Parent Form (for parents/carers of children aged 0–17 years). This study aimed to determine the responsiveness and minimal important difference (MID) values of the three scales developed for use in paediatric burn services and research. Participants were recruited by 15 UK Burn Services. Participants completed the appropriate CARe Burn Scale and a set of appropriate comparison validated measures, at three time points: 4 weeks (T1), 3 months (T2) and 6 months (T3) post-burn injury. Spearman’s correlation analysis and effect sizes based on Cohen’s d thresholds were reported and MID values were calculated. At baseline, 250 participants completed the Child Form, 69 completed the Young Person Form, and 320 completed the Parent Form. A total of 85–92% of participants were retained at follow up. The tested CARe Burn Scales were all responsive to change over time. MID values were created for all subscales and ranged from 2 to 11 for the Child Form, 3 to 14 for the Young Person Form and 3 to 10 for the Parent Form. The CARe Burn Scales for children, young people and parents are responsive to change over time. The scales are freely available for clinical and research use.

Early initiation of breastfeeding is an effort to provide colostrum which is rich protective factors. This study aimed to determine the effect of early initiation of breastfeeding on breastmilk volume. This research use quasi experimental. The results showed that the Mann-Whitney test obtained a value of p=0.000 < of α=0.05, there was an effect on breastmilk volume in mothers who did early initiation of breastfeeding. Implementation of early initiation of breastfeeding in case group was 100% otherwise not done in control group, the duration 64% hasn’t been standardized, the breastmilk volume on the third day after early breastfeeding initiation was categorized sufficient (56%) and a lot 40%, which was not 76% breastmilk volume is lacking, there is a difference on breastmilk volume in mothers who have early initiation of breastfeeding and do not have. There is an effect on breastmilk production. It is expected that the role of midwives in providing information to mothers before giving birth about the importance of early breasfeeding initiation. It is expected that midwives will emphasize more on the duration of skin to skin contact, according to minimum standards of 1 hour, Rumkit Tk II Prof. Dr. J.A. Latumeten is expected to do early initiation of breastfeeding as a fixed procedure in the maternity room.

Se describen las diferentes aplicaciones que puede tener la versión argentina de la escala Vocal Tract Discomfort (VTD), herramienta de autovaloración de síntomas o sensaciones que pueden presentarse en sujetos con alteraciones de la voz o en riesgo de presentarlas. Esta herramienta ha sido adaptada de su versión original en inglés y validada al español argentino para su utilización en detección de sujetos en riesgo vocal, para complementar el diagnóstico subjetivo y objetivo de la voz, para monitorear las sensaciones del paciente en la terapéutica y para poder comparar y discutir con resultados de investigaciones en diferentes países del mundo; donde también ha sido validada para su uso clínico e investigativo.

This thesis aims to know the completed learning results of students after the study model of Course Review Horay applied to the science subjects of grade IV SD Negeri Bangunrejo. The research method used by quasy-experiment. Data collection techniques in research use tests and interviews. Data analysis techniques with steps: average score and standard deviation, normality test and z test. The results showed the results of studying the IPA of grade IV students of SD Negeri Bangunrejo after the Course Review Horay model was significantly completed.

While fecal incontinence and constipation can be measured through physiological testing, the subjective experience of severity and impact on health-related quality of life lead to both being most effectively captured through patient-reported measures. Patient-reported measures of severity and impact help to determine baseline symptoms, guide clinical decision making, and compare various treatments. Here, we take pause to review the psychometric qualities that make effective instruments, and discuss some of the most commonly used instruments along with the reasons behind their use. In addition, we highlight the benefits of a standardized instrument designed to evaluate the major symptoms of patients presenting with pelvic floor disorders (including fecal incontinence and constipation). Ultimately, we aim to provide guidance in choosing appropriate instruments for clinical and research use.

Despite broad support for hydroxyurea (HU) therapy, suboptimal adherence is reported for youth with sickle cell disease. Valid adherence measurement is crucial to understanding the relationship between medication behavior, disease response, and patient-centered health outcomes. The current pilot study examined the feasibility of the Wise electronic device for longitudinal HU adherence measurement in a sample of 36 youths prescribed HU. The study also explored the association between HU adherence, as measured by the Wise device, with other adherence measures (ie, family report, lab values, pill count, and medication possession ratio). A measure of family-reported acceptability was also completed. Overall, results supported the feasibility of the Wise device (rate of consent=82%, device use=75%, device failure=3%) for HU adherence measurement and most families rated their experience using their device positively (favorable responses ranged from 67% to 100%). Associations between HU adherence, as measured by the Wise device, and other adherence measures were not significant. Overall, the feasibility was supported. The Wise device allows longitudinal measurement of adherence with HU from initiation as a young child (ie, with liquid formulations) through adolescence and provides a novel means of adherence measurement for both clinical and research use.

Too many pre-clinical experiments are giving results which cannot be reproduced. This may be because the experiments are incorrectly designed. In “Completely randomized” (CR) and “Randomised block” (RB) experimental designs, both the assignment of treatments to experimental subjects and the order in which the experiment is done, are randomly determined. These designs have been used successfully in agricultural and industrial research and in clinical trials for nearly a century without excessive levels of irreproducibility. They must also be used in pre-clinical research if the excessive level of irreproducibility is to be eliminated. A survey of 100 papers involving mice and rats was used to determine whether scientists had used the CR or RB designs. The papers were assigned to three categories “Design acceptable”, “Randomised to treatment groups”, so of doubtful validity, or “Room for improvement”. Only 32 ± 4.7% of the papers fell into the first group, although none of them actually named either the CR or RB design. If the current high level of irreproducibility is to be eliminated, it is essential that scientists engaged in pre-clinical research use “Completely randomised” (CR), “Randomised block” (RB), or one of the more specialised named experimental designs described in textbooks on the subject.

ObjectiveThe success of treatment planning relies critically on our ability to predict the potential benefit of a therapy. In colorectal cancer (CRC), several nomograms are available to predict different outcomes based on the use of tumour specific features. Our objective is to provide an accurate and explainable prediction of the risk to die within 10 years after CRC diagnosis, by incorporating the tumour features and the patient medical and demographic information.DesignIn the prostate, lung, colorectal and ovarian cancer screening (PLCO) Trial, participants (n=154 900) were randomised to screening with flexible sigmoidoscopy, with a repeat screening at 3 or 5 years, or to usual care. We selected patients who were diagnosed with CRC during the follow-up to train a gradient-boosted model to predict the risk to die within 10 years after CRC diagnosis. Using Shapley values, we determined the 20 most relevant features and provided explanation to prediction.ResultsDuring the follow-up, 2359 patients were diagnosed with CRC. Median follow-up was 16.8 years (14.4–18.9) for mortality. In total, 686 patients (29%) died from CRC during the follow-up. The dataset was randomly split into a training (n=1887) and a testing (n=472) dataset. The area under the receiver operating characteristic was 0.84 (±0.04) and accuracy was 0.83 (±0.04) with a 0.5 classification threshold. The model is available online for research use.ConclusionsWe trained and validated a model with prospective data from a large multicentre cohort of patients. The model has high predictive performances at the individual scale. It could be used to discuss treatment strategies.

Dysmenorrhea is menstruation accompanied by pain or cramps in the lower abdominal area when approaching menstruation. One way to reduce dysmenorrheal pain is to use non-pharmacological therapy with dysmenorrhea exercises. Dysmenorrhea is a relaxation technique for reducing dysmenorrheal pain, when exercise is done regularly and the movement is appropriate then the muscles are tense to relax and reduce the intensity of dysmenorrhoeal pain during contractions. The purpose of this research is to know Influence of Dysmenorrhea Gymnastic on Change of Pain Level on Diploma Nursing Student at STIKes WijayaHusada Bogor in 2016. This research type is Quasi Eksperimen with Non Random Pretest &Postest Control Group Design design. Sampling method in this research use Purposive Sampling technique with sample number 32 responden. Data collection was obtained through observation with pain scale observation sheet and gymnastics with standard operational procedure of dysmenorrhenal exercises. The result of bivariate analysis using Wilcoxon test, in the intervention group obtained value (ρ =, 001 or ρ 0,05). The results of the analysis of differences in decreased levels of dysmenorrhea pain in both groups with Mann-Whitney test showed an average value of the difference in the decrease in the scale of dysmenorrhea pain before and after intervention (ρ = 000 or ρ

Perinatal death is the birth of life is the perfect outcome of conception from the mother who has been separated has signs of his life regardless of age of pregnancy. This study aims to study the relationship of low birth weight babies (BBLR) with perinatal mortality in the Perinatology Room RSUD. dr. M. Yunus Bengkulu. This research use cross sectional design. Population in this research all newborn in perinatology room of RSUD dr. M. Yunus Bengkulu in January-December 2016 as many as 653 people consisting of 293 people with LBW and 360 people not BBLR. Proportional sampling random sampling technique so that the number of samples will be taken as many as 87 people who consist of 39 babies babies with LBW and 48 babies who are not LBW. The data collection in this study used secondary data by looking at documentary documentation in the Perinatology Room of RSUD. dr. M. Yunus Bengkulu. Data analysis technique done by univariate and bivariat analysis with Chi-Square statistical test (c²) through SPSS program. The results of the study were : there were 52 (59.8%) infants who did not experience perinatal death, 48 (55.2%) of babies born not BBLR, there was a significant correlation between low birth weight infant with perinatal mortality in room perinatologi RSUD. dr. M. Yunus Bengkulu with moderate category, and low birth weight babies were at risk 5 times perinatal mortality when compared with infants who are not low birth weight (LBW). It was expected that midwives could provide counseling to pregnant women to routinely check pregnancy, so that later could reduce complications arising from pregnancy in mothers who were at high risk.Keywords : baby, low birth weight, perinatal death

Objective This study aims to increase the empowerment of active case finding through counseling the Flipchart containing the social determinants of Tuberculosis. Methods The research use qualitative and quantitative method. The subjects of the study were 200 samples obtained by using Slovin formula. Data collected using questionnaire and in-depth interview with the samples. Data analysis using Path Analysis statistics to find the link between knowledge and attitudes toward TB incidence (2,521) for quantitative data tested by Wilcoxon. Results Average score of knowledge before 41.86 and after intervention 102.34 with a value of p = 0.001 and attitudes showed that there were differences before and after intervention where the value of p = 0.001 discussion and conclusions; knowledge of attitudes and case-finding actions before and after intervention increased. Conclusion The result of the study showing that the model of flipchart intervention to increase knowledge of housewives and cadres finding TB cases.

In this commentary, we present a follow-up of two articles published in 2017 and 2018 about road traffic crashes, which is an important public health issue in Africa and Burkina Faso. The first article reported on a research project, conducted in partnership with local actors involved in road safety, carried out in Ouagadougou in 2015. Its aim was to test the effectiveness, acceptability, and capacity of a surveillance system to assess the number of road traffic crashes and their consequences on the health of crash victims. Several knowledge translation activities were carried out to maximize its impact and were reported in the 2018 article published in HRPS: monthly reports presenting the research data, large-format printed maps distributed to the city’s police stations, and a deliberative workshop held at the end of the research project. The present commentary presents our efforts to deepen our understanding of the impacts of the knowledge translation strategy, based on follow-up interviews, 18 months after the workshop, with the heads of the road traffic crash units in Ouagadougou police stations (n = 5). Several benefits were reported by respondents. Their involvement in the process prompted them to broaden their knowledge of other ways of dealing with the issue of road crashes. This led them, sometimes with their colleagues, to intervene differently: more rapid response at collision sites, increased surveillance of dangerous intersections, user awareness-raising on the importance of the highway code, etc. However, sustaining these actions over the longer term has proven difficult. Several lessons were derived from this experience, regarding the importance of producing useful and locally applicable research data, of ensuring the acceptability of the technologies used for data collection, of using collaborative approaches in research and knowledge translation, of ensuring the visibility of actions undertaken by actors in the field, and of involving decision-makers in the research process to maximize its impacts.

The use of research in public health policymaking is one of the prerequisites for successfully implemented health policies which have better population health as an outcome. This policy process is influenced by the actors involved under the policy umbrella, with inter-related contextual factors and specific structural and institutional circumstances. Our study investigates how policymakers’ research capacities influence the use of research in the health policy process and identify areas where capacity-building interventions give the most meaning and impact. Furthermore, we investigate policymakers’ research engagement and use this to inform public health policy in the public sector in Denmark. We collect and report data using Seeking, Engaging with, and Evaluation Research (SEER) methodology. Policymakers are reported to have research capacity, but it is questionable how those competences have actually been used in policymaking. Decision-makers were often not aware or did not know about the existing organizational tools and systems for research engagement and use and two third of respondents had not been part of any research activities or had any collaboration with researchers. Overall, research use in public health policymaking and evaluation was limited. As a conclusion, we propose that capacity-building interventions for increasing research use and collaboration in EIPM should be context-oriented, measurable, and sustainable in developing individual and organizational competences.

Background: Many mothers do not know about the benefits of Breast Crawl. Often mothers have an improper understanding, such as not having to breastfeed the baby because the breast milk has not come out or because the milk that comes out first and yellow is the dirt and stale.Purpose: The purpose of this research is to know the relationship of postpartum knowledge about Breast Crawl in newborn with the smoothness of milk production.Method: This research use analytical method with cross sectional approach. The study was conducted on May 29 to June 23, 2018. The population in this study were all post partum mothers in Sri Widayati Wiwik BPS, SST Tanggungan Ngraho Sub-district Bojonegoro Regency in 2018 as many as 22 people, the sample size of 22 postpartum women was taken by purposive sampling technique. The instrument used is a questionnaire, then performed data processing through editing, coding, scoring and tabulating and analysis of data with Cross tables.Results: The results showed that 22 postpartum mothers in BPS Wiwik Sri Widayati, SST Tanggungan Ngraho Sub-district Bojonegoro Regency is knowledgeable good of 11 people, more than half the smoothness of breast milk production smoothly for 14 people (63,64%).Conclusion: There is relation of maternal knowledge about Breast Crawl on newborn with smoothness of breast milk production at BPS Wiwik Sri Widayati, SST Tanggungan Ngraho Sub-district Bojonegoro Regency. From the results of this study should postpartum mother can improve knowledge especially about Breast Crawl in newborn by coming to counseling conducted by health workers at Maternal & Child Health Centre every month

Residual dried blood spots from millions of newborns are being stored and used for research. The state of Michigan proactively developed a broad consent process for research use of newborns' blood spots. However, the extent to which mothers make informed choices about this research is unclear. A descriptive, qualitative study was conducted examining this issue. Twenty-nine observations of the consent process and 20 semistructured interviews were conducted with mothers on the postpartum unit of a large, academic hospital in Michigan. Content analysis of the transcripts was conducted. While most mothers agreed to donate the blood spots (n = 14/20; 70%), findings indicated that most decisions were uninformed (n = 16/20; 80%), as mothers lacked knowledge of biobanking research. Misunderstandings about anonymity, the consenter's credentials, and entity conducting the research seemed to influence decision making. Suggestions for improving the consent process include (1) changing the venue of blood spot education and consent from the postpartum period to the perinatal period, (2) strengthening the depth of information and delivery of information provided about the topic, including ethical and values clarification, and (3) increasing consenter education and training. Implementation may help increase the proportion of informed decisions.

Masalah yang umum muncul yang dialami oleh pasien yang menjalani terapi hemodialisa berkaitan dengan ketidakpatuhan mereka terhadap intake cairan. Ketidakpatuhan pasien gagal ginjal dapat menyebabkan kelebihan volume cairan dalam tubuh. Pemantauan keberhasilan manjemen intake cairan dapat diukur dengan Intradialytic Weight Gain (IDWG). IDWG dipengaruhi oleh beberapa faktor, salah satunya adalah efikasi diri. Penelitian ini bertujuan untuk mengetahui hubungan antara efikasi diri pembatasan cairan dengan IDWG pada pasien gagal ginjal kronik yang menjalani hemodialisa di RSUD Pasar Minggu. Penelitian ini menggunakan desain penelitian survei analitik dengan metode Cross Sectional. Efikasi diri pembatasan cairan diukur dengan menggunakan kuesioner, sedangkan IDWG diobeservasi selama pre dan post hemodialisa sesuai dengan jadwal hemodialisa pasien. Dari 40 responden yang menjalani hemodialisis di RSUD Pasar Minggu, 20 pasien memiliki efikasi diri tinggi dan 2- pasien lagi memiliki efikasi diri rendah. Sedangkan rata-rata kenaikan IDWG pada pasien adalah 2,188 kg. Uji statistikmenggunakan Man Whitney test menunjukkan adanya hubungan antara efikasi diri pembatasan cairan dengan IDWG (p = 0,001, A: 0,05). Dengan demikian, efikasi diri dapat mempengaruhi IDWG

SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been found capable of inducing long term effects commonly referred to as post-acute sequelae of SARS-CoV-2 (PASC) or long COVID. To define the molecular basis of this condition, we compared the short- and long-term responses to influenza A virus and SARSCoV-2 in the golden hamster model. These data demonstrated that SARS-CoV-2 resulted in sustained changes to lung, kidney, and brain. The most significant change in response to SARS-CoV-2 was observed in the olfactory bulb, where persistent inflammation was visible beyond one month post infection. This was characterized by microglial activation, pro-inflammatory cytokine production, and a Type I interferon (IFN-I) response in the absence of detectable virus. Given the connection between olfactory bulb injury and neurological disorders, we postulate that this prolonged inflammation is an underlying cause of long COVID. Funding Information: This work was funded by generous support from the Marc Haas Foundation, the National Institutes of Health (NCI (R01CA234614) and NIAID (2R01AI107301) and NIDDK (R01DK121072 and 1RO3DK117252) to Department of Medicine, Weill Cornell Medicine (R.E.S.)), and DARPA’s PREPARE Program (HR0011-20-2-0040). The work was further funded by NINDS (NS111251, NSO86444, NSO86444S1)(V.Z., R.A.S.). Ethics Approval Statement: The Tissue Procurement Facility operates under Institutional Review Board (IRB) approved protocol and follows guidelines set by Health Insurance Portability and Accountability Act (HIPAA). Experiments using samples from human subjects were conducted in accordance with local regulations and with the approval of the IRB at the Weill Cornell Medicine. The autopsy samples are considered human tissue research and were collected under IRB protocols 20-04021814 and 19-11021069. All autopsies have consent for research use from next of kin, and these studies were determined as exempt by IRB at Weill Cornell Medicine under those protocol numbers.

World Health Organization recorded that about 44% of infant deaths in 2012 happened in the first 28 daysafter birth, and 78.5% of deaths happen in the first week after births. It was estimated that 80% of infantdeaths happen at home (with little or no contact with health workers). Good quality care service for infantsespecially newborns at home is a serious challenge, thus an effort that could be performed is to optimizethe role of health workers in the community by doing homevisit.The goal of this researchto identify theself-efficacy of postpartum mothers before home visit and after home visit, to compare the self-efficacy ofintervention group and control group on newborn care by means of health workers role during home visit.This research use quantitative research with quasi-experimental non-equivalent control group design method.The sample of the research was health workers; each with responsibility of one fostered family of a motherin postpartum period. The research site for the intervention group was the working area of UleeKarengHealth Center, and for the control group was the working area of Baiturrahman Health Center. The result ofthe research revealed that there was a change in self-efficacy of postpartum mothers on newborn care afterthree home visits by the health workers. The difference of the average efficacy score was 12.5, with p valueof 0.0001. When the efficacy of postpartum mothers from the intervention group (who received homevisits) was compared to that of mothers from the control group, there was a significant difference found,with p value of 0.003. Home visit executed by the health workers can improve self-efficacy of thepostpartum mothers on newborn care. This can be seen from the difference between self-efficacy of thepostpartum mothers before and after home visit by the health workers.

Research in genomics and “omics” technologies is making possible “precision medicine”, a targeted approach to the diagnosis and treatment of diseases. The goal of precision medicine, and one that holds great promise in oncology, is to treat patients with drugs that target the specific genetic mutations in their tumors. The research use of cancer tissues aims to unravel the mechanisms of cancer onset and evolution. To this end, collection of cancer tissues after the death of a cancer patient represents a unique opportunity for researchers. Rapid Tissue Donation (RTD) is an advancing oncology procedure that involves the procurement of “fresh” tissue within 2–6 h following the death of a cancer patient. This window of time is ideal to preserve the high quality of tissues retrieved. Whereas traditional tissue biopsies provide researchers with a limited amount of material that is often suboptimal for research needs, RTD offers the chance to overcome these barriers.

Background: One approach to promote students’ use of research in future practice involves integrating students’ research use in supervision during practice placements. Studies examining this aspect of supervision in practice placements are lacking. Aim: To explore how practice educators perceive and emphasize research in their supervision of occupational therapy students during practice placements. Materials and methods: A qualitative study was conducted. A purposive sample was recruited, consisting of participants from community-based health services and hospitals in Norway. We conducted three focus groups and one individual interview with occupational therapists (n = 9). The qualitative data analysis was based on interpretive description. Results: We identified four integrative themes: ‘emphasis on research in supervision of students’; ‘practice educators’ research competence and awareness of research’; ‘institutionalization of research use in everyday practice’; and ‘communication and cooperation between education and practice regarding research’. Despite highlighting several benefits of research use, the practice educators focus rarely on students’ research use in practice placements. Conclusions and significance: Cooperation between practice educators and faculty members regarding students’ training in research use seems essential. Practice educators may need additional training in how research should be emphasized in supervision.

PURPOSE: To evaluate publicly available de-identification tools on a large corpus of narrative-text radiology reports. MATERIALS AND METHODS: In this retrospective study, 21 categories of protected health information (PHI) in 2503 radiology reports were annotated from a large multihospital academic health system, collected between January 1, 2012 and January 8, 2019. A subset consisting of 1023 reports served as a test set; the remainder were used as domain-specific training data. The types and frequencies of PHI present within the reports were tallied. Five public de-identification tools were evaluated: MITRE Identification Scrubber Toolkit, U.S. National Library of Medicine‒Scrubber, Massachusetts Institute of Technology de-identification software, Emory Health Information DE-identification (HIDE) software, and Neuro named-entity recognition (NeuroNER). The tools were compared using metrics including recall, precision, and F1 score (the harmonic mean of recall and precision) for each category of PHI. RESULTS: The annotators identified 3528 spans of PHI text within the 2503 reports. Cohen κ for interrater agreement was 0.938. Dates accounted for the majority of PHI found in the dataset of radiology reports (n = 2755 [78%]). The two best-performing tools both used machine learning methods—NeuroNER (precision, 94.5%; recall, 92.6%; microaveraged F1 score [F1], 93.6%) and Emory HIDE (precision, 96.6%; recall, 88.2%; F1, 92.2%)—but none exceeded 50% F1 on the important patient names category. CONCLUSION: PHI appeared infrequently within the corpus of reports studied, which created difficulties for training machine learning systems. Out-of-the-box de-identification tools achieved limited performance on the corpus of radiology reports, suggesting the need for further advancements in public datasets and trained models. Supplemental material is available for this article. See also the commentary by Tenenholtz and Wood in this issue. © RSNA, 2020

Introduction Tissue from pediatric solid tumors is in high demand for use in high-impact research studies, making the allocation of tissue from an anatomic pathology laboratory challenging. We designed, implemented, and assessed an interdepartmental process to optimize tissue allocation of pediatric solid tumors for both clinical care and research. Methods Oncologists, pathologists, surgeons, interventional radiologists, pathology technical staff, and clinical research coordinators participated in the workflow design. Procedures were created to address patient identification and consent, prioritization of protocols, electronic communication of requests, tissue preparation, and distribution. Pathologists were surveyed about the value of the new workflow. Results Over a 5-year period, 644 pediatric solid tumor patients consented to one or more studies requesting archival or fresh tissue. Patients had a variety of tumor types, with many rare and singular diagnoses. Sixty-seven percent of 1768 research requests were fulfilled. Requests for archival tissue were fulfilled at a significantly higher rate than those for fresh tissue (P > .001), and requests from resection specimens were fulfilled at a significantly higher rate than those from biopsies (P > .0001). In an anonymous survey, seven of seven pathologists reported that the process had improved since the introduction of the electronic communication model. Conclusions A collaborative and informed model for tissue allocation is successful in distributing archival and fresh tissue for clinical research studies. Our workflows and policies have gained pathologists' approval and streamlined our processes. As clinical and research programs evolve, a thoughtful tissue allocation process will facilitate ongoing research.

The objective of this study was to determine the description of kidney histology of Mus musculus after giving Nano Herbal Rhodomyrtus tomentosa (Haramonting). R.tomentosa (Haramonting) is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD), which consists of six groups of CMC 0.5% and Nano- R.tomentosa (Haramonting) at dosage of (100; 141,42; 200; 282,82; 400)mg/20g body weight. The kidneys were made into preparations by using the paraffin method and Hematoxylin Erlich-Eosin staining (HE). The results of histological kidneys showed that there is a significant difference (P0,05).

The research exemption implemented in the new EU General Data Protection Regulation (EU-GDPR) gives member states leeway in determining whether patient consent is required for secondary data use in medical research. However, even though broad consent has become common in data-rich medical research in many EU countries, giving up consent altogether is likely to be controversial. The aim of this study was to examine whether abolishing consent for secondary data use would be acceptable to patients. A questionnaire study was conducted among 700 outpatients of a northern German university hospital to assess their attitude towards use of clinical data for scientific research without consent. There was both strong willingness to give broad consent for secondary data use (468 of 503 responders, 93.0%) and strong approval of abolishing patient consent (n = 381, 75.7%) among study participants. The willingness to give consent was moderately associated with approval of the respective stipulations by the EU-GDPR. In research settings where broad consent is widely accepted (e.g. university hospitals), abolishing consent for secondary research use of clinical data will likely be acceptable to a large majority of patients.

Febrile seizures is a disease that is quite common in infants. Half of the occurrence of febrile seizures occur recurrent febrile seizures, this occurs because the child's brain development is still not optimal enough in doing self-defense against the fever, resulting in the rise of febrile seizures. Parents often panic facing the event of febrile seizures. handling fever in children is very dependent on the parents. Level of knowledge of each different mother will lead to the management of fever in different children. This study aims to determine the level of knowledge of the mother about febrile seizures in children aged 6 mounth to 5 years in Puskesmas Kampar East Kampar District in 2018. this research use accidental sampling sampling technique and data collection is done by questioner. The research was conducted on 30 May - 9 June 2018 at Puskesmas Kampar East Kampar District. Sample was 50 respondents with univariate data analysis. The results of this study indicate that the mother's knowledge level is less with the number of 36 people (72%). It is hoped for the Puskesmas to be able to make extantion program about things related to febrile definition dan febrile seizures. And for the mother around Puskesmas Kampar East Kampar District is expected to be more open to new information and more accepting suggestion from nurse and medical officer that exist, especially about information that is important and useful for family health. Key Word : Level knowledge of mother, Febrile seizures

Hypertension is widely known for its cardiovascular disease in which sufferers have blood pressure above normal blood pressure, precisely where systolic blood pressure ≥ 140 mmHg and diastolic pressure ≥ 90 mmHg measured in calm at two measurements. Compliance to medication of hypertension contributes greatly to the stability of the blood pressure. One of the efforts made to improve compliance with medication of hypertension with the chronic disease management program (Prolanis). This research aims to know the relationship of the level of compliance of taking the drug with blood pressure in patients of hypertension in chronic disease management group (Prolanis) Qita Clinic. This research use analytic research method to approach cross-sectional, in the study sample is determined by the method of purposive. This research instrument is the questionnaire MMAS-8 (Morisky Medication Adherence Scale-8) and 1 set of tools tensimeter. From the results of the research showed that respondents with high compliance as much as 14 respondents (46.7%), compliance are as many as 5 respondents (15.7%) and low compliance as much as 11 respondents (36.7%). Correlation of test results of these studies showed a relationship with medication compliance systolic blood pressure with a p value of 0.05 signifies < 0.038 and there is a connection with diastolic blood pressure with a p value of 0.05 signifies < 0.024.

Inspection of Visual Inspection of Acetic Acid (IVA) is one way of earlydetection of cervical cancer disease. This check method is an easy-to-do and inexpensivemethod, but has high yield accuracy. The Srikuncorocommunity Health centersiscommunity Health centers which has the lowest IVA examination rate that is 5 people.The purpose of this research is to know factors related to posyandu cadre motivation inexamination of IVA test in working area of The Srikuncorocommunity Healthcenters2017 This research use cross sectional method. The population of the research wasposyandu cadres in The Srikuncorocommunity Health centersarea of 90 people, with totalsample technique. Using secondary data and primary data with univariate, bivariate, andmultivariate analyzes. The research results of most cadres received poor husband support(56.7%), poor environmental support (54.4%), poor information exposure (55.6%), andmost cadres have low motivation (62.2%). There is a significant relationship betweenhusband support p = 0,000 and OR = 10,750, environmental support p = 0,000 and OR =8,883, information exposure p = 0,000 and OR = 7,593 with cadre motivation in IVA testexamination at Puskesmas Srikuncoro 2017. husband is the most influential factor withcadre motivation in IVA examination

Hypertension becomes a silent killer because in some cases it does not show any symptoms on the sufferer. The purpose of this study was to determine factors related to self care in adults who experienced hypertension in Kendal 01 health center. This research used a descriptive correlative design with cross sectional study design. Sample in this research use accidental sampling technique counted 96 respondents. The statistical test in this study used Kendall Taub's test and Chi Square Test. The result of this research can be concluded that there is a strong positive relationship between functional status with self care (p value 0,0001) (r = 0,523), Family support with self care (p value 0.0001) (r count 0,411) , And Emotional Change with self care (p value 0.0001). Then suggested to health service can give information and do home care by way of visit to every patient of hypertension.

Low Birth Weight (LBW) is an infant born with a birth weight of less than 2500 grams regardless of gestation. Birth weight is the weight of the baby weighed in 1 hour after birth. (Depkes RI, 2009). Based on WHO and UNICEF data, in 2013 about 222 million babies were born in the world, of which 16% were born with low birth weight. The percentage of LBW in developing countries is 16.5% twice that of developed countries (7%) (Scholar Unand, 2014). The purpose of this study was to determine whether there is a relationship between anemia and Smoking Habit in Pregnant Women with LBW occurrence in General Hospital Dr. Mohammad Hoesin Palembang Year 2016. This research use analytical survey method with cross sectional approach. The population in this study were all mothers who gave birth monthly in Midwifery Installation of Dr. General Hospital Mohammad Hoesin Palembang in 2016 as many as 315 respondents. The sample of this research is some of mothers who give birth enough month in Midwifery Installation of Dr. General Hospital Mohammad Hoesin Palembang Year 2016 as many as 315 respondents. ". From the results of bivariate analysis of anemic respondents with the occurrence of LBW obtained statistical test X2 count = 23.22 which means there is a significant relationship between anemia with the incidence of BBLR. Respondents smoking with the occurrence of LBWR obtained statistical test X2 count = 41.20 which means there is a relationship Meaningful between smoking and LBW incidence. From the results of this study is expected that this research can be a reference material and is a complete information and useful for the development of knowledge about LBW.

Taking advantage of its single-payer, universal insurance system, Taiwan has leveraged its exhaustive database of health claims data for research purposes. Researchers can apply to receive access to pseudonymized (coded) medical data about insured patients, notably their diagnoses, health status and treatments. In view of the strict safeguards implemented, the Taiwanese government considers that this research use does not require patients' consent (either in the form of an opt-in or in the form of an opt-out). A group of non-governmental organizations has challenged this view in the Taiwanese Courts, but to no avail. The present article reviews the arguments both against and in favor of patients' consent for re-use of their data in research. It concludes that offering patients an opt-out would be appropriate as it would best balance the important interests at issue.

All troponin assays are equal but some assays are more equal than others (with apologies to George Orwell). Measurement of cardiac troponin (cTn) using ‘high sensitivity’ cTn (hs-cTn) assays is supported by evidence-based medicine and is incorporated into the guidelines of the European Society of Cardiology1 as well as the Fourth Universal Definition of Myocardial Infarction (2018).2 The majority of diagnostic companies have launched or are in the process of launching cTn assays into routine clinical practice and for use in research trials, which meet the criteria for high sensitivity. A high sensitivity assay is defined analytically3 by the ability to measure at least 50% of a reference population and an imprecision (coefficient of variation (%CV))

Diabetic foot ulcer (DFU) is a condition of deep tissue damage associated with Diabetes Mellitus in the lower extremities. Conducted with quantitative research of single group method with pre and post test design approach, this research primarily aims to know the effectiveness of utilizing combination of Autolysis & Conservative Sharp Wound Debridement in preparing granulation on unstageable DFU. It involved 30 respondents in the wound care clinic as the research sample and used the Wound Bed Score observation sheets measured on days 1, 7 and 28. The data analysis to determine effectiveness before and after intervention was carried out using dependent t-test (paired t-test), whilst to test effectiveness of giving intervention after controlled confounder was performed by linear regression. Based on the characteristics of the respondent’s, it is revealed that most of them were female (83.3%) and have normal BMI (80%). The average age of the respondents were 55.43 years old with the duration of DM of 13.27 years with average blood sugar of 101.2 mg/dL. The highest mean difference was on the 1st day of the 28th. The statistical results of this study indicated that the mean difference values for day 1 and 7 were 0.133 (SD 1.19, p value = 0.546), mean difference of day 7 and day 28th grade was of 2.5 (SD 1.306, p value=0.0001) and mean difference between day 1 and day 28 was of 2.63 (SD 1.273, p value=0.0001). This research recommends that the further research use different research methods.

Echocardiography plays a pivotal role as an imaging modality in the modern cardiology practice. Information derived from echocardiography is definitely helpful for a patient care. The Japanese Society of Echocardiography has promoted echocardiography for a routine clinical and research use. One of the missions of the Society is to provide information that is useful for high-quality examinations. To ensure it, we believe equipment in good conditions and a comfortable environment are important for both a patient and an examiner. Thus, the Committee for Guideline Writing, the Japanese Society of Echocardiography published brief guidance for the routine use of echocardiography equipment in 2015. Recently, the importance of international standardization has been emphasized in the medical laboratories. Accordingly, the committee has revised and updated our guidance for the routine use of echocardiography equipment.

Living with a chronic illness surely can affect clients and their families. Family capacity to adapt successfully can be quite different depend on characteristic of chronic illness and family perception about the illness. Consideration of the family’s view of illness support health care professionals in finding the best resources to assist family with chronic illness. The aim of this study was to describe impact of chronic illness to clients and their family. This research use a qualitative design with descriptive phenomenological approach. Using purposive-sampling, eight families living with chronic illness were participated in this study. Colaizzi’s method which involving participants to validate results was used in the research. The theme of this study are changes in the patient's health status, family system changes and family difficulties in maintenance tasks. Conclusion of this research is that family members are the biggest support to motivate clients and also challenged as they strive to assist member diagnosed with chronic condition to stay healthy. Involving clients and families in the decision making support the efforts of families in their self-management of chronic illness. Thus nurses could provide family counseling to strengthen family coping and capacity by providing family with adequate information about illness.  Â

Antiretroviral therapy (ART) requires lifelong daily oral therapy. While patient characteristics associated with suboptimal ART adherence and persistence have been described in cohorts of HIV-infected persons, these factors are poor predictors of individual medication taking behaviors. We aimed to create and test instruments for the estimation of future ART adherence and persistence for clinical and research applications. Following formative work, a battery of 148 items broadly related to HIV infection and treatment was developed and administered to 181 HIV-infected patients. ART adherence and persistence were assessed using electronic monitoring for 3 months. Perceived confidence in medication taking and self-reported barriers to adherence were strongest in predicting non-adherence over time. Barriers to adherence (e.g., affordability, scheduling) were the strongest predictors of non-adherence, as well as 3- and 7-day non-persistence. A ten-item battery for prediction of these outcomes ( www.med.unc.edu/ncaidstraining/adherence/for-providers ) and a 30-item battery reflective of underlying psychological constructs can help identify and study individuals at risk for suboptimal ART adherence and persistence.

BackgroundLeftover samples obtained during autopsies are extremely important basic materials for forensic research. However, there are no established practices for research-related use of obtained samples.ObjectiveThis study discusses good practice for the secondary use of samples collected during medicolegal autopsies.MethodsA questionnaire was posted to all 76 departments of forensic medicine performing medicolegal autopsies in Japan, and 48 responses were received (response rate: 63.2%). As a secondary analysis, we surveyed information provided on department websites.ResultsEthical reviews conducted when samples were to be used for research varied greatly among departments, with 21 (43.8%) departments reporting ‘fundamentally, all cases are subject to review’, eight (16.7%) reporting ‘only some are subject to review’ and 17 (39.6%) reporting ‘none are subject to review’. Information made available on websites indicated that 11 departments had a statement of some type to bereaved families about the potential research use of human samples obtained during autopsies. Nine of these included a notice stating that bereaved families may revoke their consent for use. Several departments used an opt-out system.ConclusionThere is no common practice in the field of legal medicine on the ethical use for medical research of leftover samples from medicolegal autopsies. The trust of not only bereaved families but also society in general is required for the scientific validity and social benefits of medical studies using leftover samples from medicolegal autopsies through the use of opt-out consenting and offline and online dissemination and public-relations activities.

The Interdialysis Weight Gain more than 5 % of weight dry can result in negative towards patients of them hypotension , edema , shortness of breath , lightheaded and can lead to the death .Research objectives is to find interdialysis weight gain in Chronic Kidney Disease Patients. A method in this research use descriptive design .Population in this study all patients of chronic kidney disease who get hemodialisa in installation hemodialisa RSD mardi waluyo blitar are 89 peoples , uses the technique total population. Data collection is performed by measuring weight patients after hemodialisa ago and before hemodialisa next .This research result that weight gain between the two time lightweight hemodialysis 60,7%, 12,4% on average, and 26,9% of danger . Extra weight category of danger caused because patients do not adhere to diet. Recommendations from the study is expected to become an evaluation for installation hemodialisa RSD Mardi Waluyo Blitar to increase intervention on patients who get hemodialisa .

Screening tools to identify HIV-associated neurocognitive disorder (HAND) are primarily devised to detect cognitive impairment on a single occasion. With the chronicity of HIV infection and the risk of HAND developing or progressing despite viral control, it may be pertinent to repeat HAND screening at more than one time point. Despite this, there are limited data on longitudinal use of such screening tools, particularly with regard to the role of practice effects. Additionally, no guidelines currently exist on the timeframe between testing intervals, or recommendation of the magnitude of baseline impairment that warrants follow-up testing. The aim of the current paper was to review existing evidence for longitudinal validity of HAND screening tools. Only those HAND screening tools previously found to have high cross-sectional criterion validity were included. Preliminary recommendations for clinical use and future research are proposed including in international settings.

Background & Aim BACKGROUND AND AIM: Public cord blood banks have thresholds for accepting cord blood unit (CBU) collections for processing based on economic models developed using surrogate markers of suitability, i.e. volume and total nucleated cell count (TNCC). Only after processing has it been possible to look at CD34+ cell numbers and colony forming units (CFU). Since as few as 0.52 × 105 CD34+ cells can be expanded in vitro and used successfully for transplant, it is important to understand what is in the smaller collections that public bank guidelines currently prevent from being processed. Hybrid public/private cord blood banks permit economic support from the private bank to help support the public bank. They also offer an opportunity to evaluate products outside public banking thresholds because all collections are processed. AIM To present data from the first 72 private cord blood unit (CBU) collections processed for the Cord Blood Bank of Arkansas, showing the relationship between collection volume, TNCC and CD34+ cell numbers. Methods, Results & Conclusion METHODS: The CBBA is a hybrid bank, providing cord blood banking for public, private and research use. Parents are informed of the different options for banking available, document their informed consent, and then receive a collection kit to bring to the delivering obstetrician. Cord blood is collected with the placenta in utero using Pall model # 791-08 collection kits. Collections are processed within 72 h of collection at a central site with plasma and red cells removed. Pre-processing TNCC are performed with a Beckman Coulter Ac.T Diff2 cell counter and TNCC determined as follows: actual cord blood weight x WBC 103/100=TNCC. Flow cytometry is performed using the ISHAGE technique with a Beckman Coulter CytoFLOW. RESULTS Mean maternal age for CBU was 34y (range 26-45). Of 72 CBU donated (37 male, 35 female), delivery route was spontaneous vaginal for 50 (69.45%) and caesarian section for 22 (30.55%). Mean birth weight was 3341.5 g (median 3355; range 2296-4337). Mean gestational age was 38.92 weeks (median 39; range 36-41.14). CONCLUSION Data on hematopoietic potential of low volume/low TNCC products are currently available only from a hybrid or private bank. Here we show that CBU below threshold TNCC and volume for public banks can have a significant number of CD34+ cells available for expansion and use in transplant.

Introduction/Background According to RARECARE, in Europe rare cancers account for 18% of all female genital tract cancers (figure 1).1 Although the quality of UK cancer registry collection has improved significantly recently, national registries do not record treatments or outcomes nor do they obtain patient consent allowing subsequent access for research use of tissue samples. Yet the amalgamation of such clinical information and permissions is essential to facilitate evaluation of existing strategies and improve options/outcomes for patients. RaNGO, a study developed by Gynaecological Clinical Studies Group, demonstrates the feasibility of collecting accessible information about such cancers in the UK. It includes the development of a tissue bank with appropriate patient consents, for suitable ethically approved translational research projects. Methodology Patients with a specified rare gynaecological cancer (see table 1) are offered participation in RaNGO a multicentre, non-randomised study to create an information repository to audit treatments/outcomes and a virtual tissue bank for future translational research. Consent is obtained for collection/retention of anonymised data and the provision of appropriate bloods, bodily fluids and tissue samples. Specific informed consent is sought for the exchange/release of data from the relevant National Cancer Registries (UK) for local audit purposes and for sharing hemi-aggregated RaNGO data internationally in the future. Results Of the 44 UK gynaecological cancer centres - 5 are currently fully open to recruitment, 10 are in set-up and 20 patients are recruited but up to date details will be provided in November 2019. Conclusion RaNGO demonstrates the safety/feasibility of acquiring blood, tumour samples and fluid from women with rare neoplasms of gynaecological origin from across the UK. The collection of detailed information about such patients will provide a much-needed benchmark of current management strategies. Involving all 44 gynaecological cancer centres will facilitate the development of future trials to improve outcomes for these patients Disclosure Nothing to disclose.

Background Despite the increased emphasis placed on the use of evidence for policy development, relatively few initiatives have been developed to support evidence-informed decision-making, especially in West Africa. Moreover, studies examining the conditions under which policy-makers use research-based evidence are still scarce, but they show that their attitudes and opinions about research are one of the main determinants of such use. In February 2017, Burkina Faso’s Minister of Health planned to create a unit to promote evidence-informed decision-making within the ministry. Before the unit was set up, documenting the attitudes towards research at the highest levels of his Ministry appeared profitable to the unit’s planning. Method Individual interviews were conducted by the author with 14 actors positioned to consider evidence during decision-making from the Burkina Faso’s Minister of health cabinet. An interview grid was used to explore several themes such as attitudes towards research, obstacles and facilitators to research use, example of research use in decision-making and finally, ways to increase decision-makers’ participation in knowledge transfer activities. Interviews were partially transcribed and analysed by the author. Results The results show a mixed attitude towards research and relatively little indication of research use reported by respondents. Important obstacles were identified: evidence inaccessibility, lack of implementation guidelines, absence of clear communication strategy and studies’ lack of relevance for decision-making. Many suggestions were proposed such as raising awareness, improving access and research communication and prioritizing interactions with researchers. Respondents agree with the low participation of decision-makers in knowledge transfer activities: more leadership from the senior officials was suggested and greater awareness of the importance of their presence. Conclusions The conclusion presents avenues for reflection and action to increase the potential impact of the knowledge transfer unit planned within the Ministry of Health of Burkina Faso. This innovative initiative will be impactful if the obstacles identified in this study and policy-makers’ preferences and needs are taken into account during its development and implementation.

BACKGROUND : Self-efficacy is an individual's belief in his ability to organize and perform the specific tasks required to get results as expected. Compliance is the extent to which a person's behavior is committed to a therapeutic regimen that has been agreed with a health care provider. The purpose of this study was to determine the correlation of self efficacy with low salt diit adherence in elderly hypertension in Jelbuk District Jember Working Area. SUBJECT AND METHODE : This research use correlation research design with cross sectional approach. The population in this study were 746 elderly with hypertension, with purposive sampling technique and proportional sampling with inclusion criteria and exclusion criteria were obtained as many as 149. RESULTS : The result of hypertension elderly with high self efficacy was 85.2%, low self efficacy 14.8%. Low salt with obedient 75.8%, low salt diit adherence with non-adherence 24.2%, self efficacy in good category and obdient in low-salt diit equal to 86,6%, whereas self efficacy less with low salt diit compliance in adherence category 13,6% using Chi Square analysis obtained p value 0.000 which means H1 accepted which means there is a relationship of self efficacy with low salt diit compliance. CONCLUSION : In conclusion there is a relationship of self efficacy with adherence of low salt diit in elderly hypertension In Work Area Puskesmas Jelbuk Jember regency. It is expected that elderly increase self efficacy so that they coul run in low-salt diit.

Background: Elderly is the final stage of the human life cycle, that is part of the inevitable life process and will be experienced by every individual. At this stage the individual undergoes many changes both physically and mentally, especially setbacks in various functions and abilities he once had. Preliminary study in Social House Tresna Wreda Yogyakarta Budhi Luhur Units there are 16 elderly who experience physical immobilization. In the social house has done various activities for the elderly are still active, but the elderly who experienced muscle weakness is not able to follow the exercise, so it needs to do ROM (Range Of Motion) exercise. Objective: The general purpose of this research is to know the effect of Range Of Motion (ROM) Active Assitif training to increase the range of motion of joints in elderly who experience physical immobility at Social House of Tresna Werdha Yogyakarta unit Budhi Luhur. Methode: This study was included in the type of pre-experiment, using the One Group Pretest Posttest design in which the range of motion of the joints before (pretest) and posttest (ROM) was performed ROM. Subjects in this study were all elderly with impaired physical mobility in Social House Tresna Wreda Yogyakarta Unit Budhi Luhur a number of 14 elderly people. Data analysis in this research use paired sample t-test statistic Result: The result of this research shows that there is influence of ROM (Range of Motion) Active training to increase of range of motion of joints in elderly who experience physical immobility at Social House Tresna Wredha Yogyakarta Unit Budhi Luhur. Conclusion: There is influence of ROM (Range of Motion) Active training to increase of range of motion of joints in elderly who experience physical immobility at Social House Tresna Wredha Yogyakarta Unit Budhi Luhur.

Background: About 80% of women will feel back pain at some point during pregnancy. Most back pain during pregnancy occurs due to changes in the spinal muscles which are as much as 70%. and 30% of back pain during pregnancy may be due to irregularities in the condition of the spine that occurred earlier. Effleurage massage is a form of massage by using a palm that gives a gentle pressure to the top of the body in a circular direction repeatedly. Purpose: Knowing the scale of pain in pregnant women who have back trimester III back pain before and after effleurage massage done at RB CI Semarang. Research methods: Type of research used quantitative method, population in this research is trimester III pregnant woman in RB CI Semarang a number of 40 Respondent with collecting data obtained by doing effleurage massage with pre experimental design using pretest - postest one group design. Sampling technique in this research use Purposive Sampling technique. Results: the results obtained before the effleurage massage performed on pregnant women on average - scale pain 7, while after effleurage massage performed on average pregnant women decreased to pain scale 3 . Conclusion: There is effect of effleurage massage on back pain in pregnant mother of trimester III. Keywords: effleurage massage, back pain Literature : 17 (2005 – 2017 ) Abstract About 80% of women will feel back pain at some point during pregnancy. Most back pain during pregnancy occurs due to changes in the spinal muscles which are as much as 70%. and 30% of back pain during pregnancy may be due to irregularities in the condition of the spine that occurred earlier. Effleurage massage is a form of massage by using a palm that gives a gentle pressure to the top of the body in a circular direction repeatedly. Knowing the scale of pain in pregnant women who have back trimester III back pain before and after effleurage massage done at RB CI Semarang. Type of research used quantitative method, population in this research is trimester III pregnant woman in RB CI Semarang a number of 40 Respondent with collecting data obtained by doing effleurage massage with pre experimental design using pretest - postest one group design. Sampling technique in this research use Purposive Sampling technique. the results obtained before the effleurage massage performed on pregnant women on average - scale pain 7, while after effleurage massage performed on average pregnant women decreased to pain scale 3 . There is effect of effleurage massage on back pain in pregnant mother of trimester III. Keywords : effleurage massage, back pain

Child sexual abuse (CSA) is common, severe, and substantively contributes to the global burden of disease through its impact on physical, mental, and behavioral health problems. While CSA is preventable through non-justice system response efforts, the vast majority of resources support criminal justice efforts to identify, prosecute, punish and monitor offenders after CSA has already occurred. Policy makers have not supported CSA prevention efforts in part because the public does not view CSA as a preventable public health problem. Here, we describe a program of research to be conducted to bridge the gaps between expert and public opinion about CSA as a preventable public health problem. We propose such research use a three-step approach to alter the way experts communicate about CSA to increase audiences' understanding of CSA as preventable. The three steps are: 1) identify consensus expert and public perspectives about CSA and the differences between these perspectives; 2) develop and test communication strategies to align public with expert perspectives; and 3) broadly disseminate validated communication strategies. Through this approach, we seek to develop and disseminate an informed communications strategy that effectively and accurately translates the science of CSA prevention to the public and the media.

The covid-19 pandemic period caused activities and the need for recovery paralysis to be disrupted, in other studies not much has analyzed training activities and athletic recovery during the covid-19 pandemic. Motion outside this research use non-experimental quantitative research methods and is written descriptively. The data was obtained by filling out the Google Form filled in by 13 Paralympian respondents. The data were analyzed by calculating the percentage. Thes results are Paralympian with sleep recovery 86% with the category always score and exercise activity reaches a percentage rate of 74,9%, the frequency of exercise gets an average of 51,3% with the occasional category, the intensity of the exercise has an average number of 63,2% with the frequent category, and the duration of exercise has an average rate of 53,8% with occasional category. The conclusions are that when the covid-19 pandemic hit, with the government’s provisions that physical distancing does not limit the paralysis to carry out activities and carry out maximum recovery. The sleep to be the highest percentage of 86% with the always the data average reaches 73 which is the value of 81%-100%, that the exercise activity or anaerobic and aerobic exercise has an average number of 74,9 with the frequent category, the intensity of light-moderate exercise has an average number the average was 63,2 with the frequent category and the exercise duration had 30-45 minutes a day the mean score was 53,8 with the occasional category. Suggestion by staying consistent in doing exercise activities gradually.

Academic pathology departments will be dramatically affected by proposed United States federal government regulatory initiatives. Pathology research will be substantially altered if proposed changes to the Common Rule (Code of Federal Regulations: Protection of Human Subjects title 45 CFR 46) and regulations governing the return of individual research results are approved and finalized, even more so now that the Precision Medicine initiative has been launched. Together, these changes are disruptive influences on academic pathology research as we know it, straining limited resources and compromising advances in diagnostic and academic pathology. Academic research pathologists will be challenged over the coming years and must demonstrate leadership to ensure the continued availability of and the ethical use of research pathology specimens.

Incidence of phlebitis is an indicator of the quality of hospital services with minimal rate of ≤1,5% standard. The incidence of phlebitis in Hospital AR. Bunda Prabumulih still high ranging from 8% to 17%. Highest incidence of phlebitis is in February amounted to 17%. This research to analyze the factors related incidence phlebitis in patient intravenous catheter. This research use description of the correlation with cross sectional method. This research was conducted in the surgical room (ibnu sina) AR. Bunda Prabumulih Hospital. Involving 92 respondens using total sampling and observation sheet as a measuring instrument. The method of analysis used in this research is both univariate and bivariate data. The result this test analysis research show that there is relationship between age and type of intravenous fluid toward phlebitis with significant influence p-value=0.000. In addition, intravenous catheter care and comorbidities no significant relationship with the incidence of phlebitis with p-value=0.643. The result is expected to be a reference to hospital, mainly for medical personnel in carrying out act of intravenous catheters still consider the factors supporting the occurence of phlebitis.

The purpose of this research was to assess the impact of an educational intervention on paternal knowledge, attitudes, and support about newborn screening (NBS) and dried blood spots (DBS). Participants (n = 147) were randomized into one of two groups. The results from this study indicated that video education tools about NBS and DBS is associated with significantly increased knowledge, support, and satisfaction for both NBS and research use of DBS and an opt-out consent approach for DBS among fathers.

NGR reports funding by NIGMS grant R35GM119582. BMA is supported by Bill and Melinda Gates Foundation through the Global Good Fund. SP and IMB were funded by the Armed Forces Health Surveillance Branch (GEIS: P0116_19_WR_03.11). Introduction: High quality epidemic forecasting and prediction are critical to support response to local, regional and global infectious disease threats. Other fields of biomedical research use consensus reporting guidelines to ensure standardization and quality of research practice among researchers, and to provide a framework for end-users to interpret the validity of study results. The purpose of this study was to determine whether guidelines exist specifically for epidemic forecast and prediction publications. Methods: We undertook a formal systematic review to identify and evaluate any published infectious disease epidemic forecasting and prediction reporting guidelines. This review leveraged a team of 18 investigators from US Government and academic sectors. Results: A literature database search through May 26, 2019, identified 1467 publications (MEDLINE n = 584, EMBASE n = 883), and a grey-literature review identified a further 407 publications, yielding a total 1777 unique publications. A paired-reviewer system screened in 25 potentially eligible publications, of which two were ultimately deemed eligible. A qualitative review of these two published reporting guidelines indicated that neither were specific for epidemic forecasting and prediction, although they described reporting items which may be relevant to epidemic forecasting and prediction studies. Conclusions: This systematic review confirms that no specific guidelines have been published to standardize the reporting of epidemic forecasting and prediction studies. These findings underscore the need to develop such reporting guidelines in order to improve the transparency, quality and implementation of epidemic forecasting and prediction research in operational public health. Publisher PDF