Author: "Rajab, A." / Topic: medicine.medical_specialty - Searchworks@Jio Institute Digital Library Search Results

802 results on '"Rajab, A."'

1. The Role of Diagnostic Laparoscopy in Chronic Pelvic Pain

Author: Jwan Abid, Israa Abid Al-Karim, and Waleed Rajab
Subjects: 03 medical and health sciences, medicine.medical_specialty, 030219 obstetrics & reproductive medicine, 0302 clinical medicine, business.industry, 030220 oncology & carcinogenesis, Pelvic pain, medicine, Pharmacology (medical), Diagnostic laparoscopy, Radiology, medicine.symptom, business
Abstract: One of the commonest symptomatology in gynecological outpatient clinics is chronic pelvic pain, it accounts for 10% of gynecologist’s general clinics patients. The study aimed to To evaluate the role of laparoscopy in evaluation of CPP, and its correlation with clinical examination and vaginal ultrasound examination. The present prospective study was done in the Department of Obstetrics and Gynecology Salah Al-Deen general hospital in Tikrit city from 1stApril- 31st August 2020. The study sample consists of 30 patients with chronic pelvic pain, according to the ACOG criteria, with a convenient sampling method. The data collection done through: a designed closed and open-ended questionnaire, physical examination, transvaginal ultrasound & laparoscopic examination for the 30 patients for evaluation of chronic pelvic pain. By laparoscopic examination (90%) of patients had positive findings, pelvic examination identified (89%) of them correctly. Those with negative findings in laparoscopy was (10%) of patient, (33.3%) of them were diagnosed as negative by pelvic examination, there were miss diagnosis in (67%) of the negative patient and (11.1%) of positive diagnosed patient, this was a statically significant relation. Sensitivity of TVS was 85%, versus 89% for the pelvic examination. Specificity for TVS, and pelvic examination was (100%), (33%) respectively. Accuracy of the test for TVS, and pelvic examination was (87%), (83%) respectively. Exploratory laparoscopy provides a definitive diagnosis in 90% of women complaining of unexplained CPP. The surgical treatment of these lesions improves painful symptomatology in 70% of women .
Published: 2023

2. Tumor glioneuronal leptomeníngeo difuso: diagnóstico y tratamiento con un caso ilustrativo

Author: Rajab Al-Ghanem, Rafael Luque Barona, Osamah Abdullah El-Rubaidi, José Manuel Galicia Bulnes, and Alicia Godoy-Hurtado
Subjects: Gynecology, medicine.medical_specialty, business.industry, Medicine, Surgery, Neurology (clinical), business
Abstract: Resumen El tumor glioneuronal leptomeningeo difuso es una entidad infrecuente, con un curso indolente; fue descrito en la clasificacion de los tumores del sistema del sistema nervioso central de la OMS 2016. Presentamos el caso de un varon de 11 anos que comienza con un cuadro clinico inespecifico de cefalea, dolor lumbosacro e hidrocefalia comunicante. En el curso clinico aparecen crisis epilepticas con lesiones nodulares en RM craneal; fue diagnosticado de meningitis tuberculosa y tratado con tuberclostaticos. Ante un deterioro clinico progresivo, a pesar del tratamiento, y empeoramiento de los hallazgos en RM craneoespinal, se le realiza biopsia cerebral y de leptomeninges que confirma el diagnostico de tumor glioneuronal leptomeningeo difuso. El tumor glioneuronal leptomeningeo difuso debe incluirse en el diagnostico diferencial de los cuadros que se presentan con hidrocefalia comunicante y lesiones leptomeningeas. Se precisa un diagnostico histologico precoz mediante biopsia para establecer un tratamiento adecuado.
Published: 2022

3. COVID-19 infection mortality risk in Iranian patients with type 2 diabetes, hypertension and obesity

Author: Manouchehr Nakhjavani, Nasrin Baiat Paridari, Fatemeh Ghaemi, Soghra Rabizadeh, Alireza Esteghamati, Mahdi Shadnoush, Armin Rajab, and Mostafa Khoshabi
Subjects: medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), business.industry, COVID-19, Comorbidity, General Medicine, Type 2 diabetes, Iran, medicine.disease, Obesity, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Risk Factors, Internal medicine, Hypertension, Diabetes Mellitus, medicine, Humans, business
Abstract: Diabetes mellitus and hypertension are highly prevalent among patients with severe COVID-19.To study the mortality risk of COVID-19 infection in patients with type 2 diabetes and additive effect of hypertension and obesity in the Iranian population.This was a cross-sectional survey of the national COVID-19 registry from the Iranian Ministry of Health. The medical status of 22 002 patients with COVID-19 between 1 March and 30 April 2020 was analysed.Patients with type 2 diabetes had a higher risk of mortality with an odds ratio (OR) of 1.67 [95% confidence interval (CI): 1.53-1.82, P0.001]. The risk of mortality was also high in patients with diabetes and hypertension, with an odds ratio of 1.76 (95% CI: 1.56-1.99, P0.001). The odds ratio of the risk of mortality in patients with diabetes, hypertension and obesity was 1.87 (95% CI: 1.35-2.58, P0.001).Type 2 diabetes, hypertension and obesity each predict mortality in Iranian patients with COVID-19, and when they are present together, patients have a greater risk of mortality.خطر الوفاة الناجمة عن الإصابة بكوفيد-19 لدى المرضى الإيرانيين المصابين بالنمط 2 من السكري وارتفاع ضغط الدم والسمنة.مهدي شدنوش، صغرا ربيع زاده، علي رضا إستغاماتي، منوشهر ناخجواني، نسرين بيات باريداري، مصطفى خشابي، أرمين رجب، فاطمة غامي.ينتشر داء السكري وارتفاع ضغط الدم انتشارًا كبيرًا بين المرضى المصابين بحالة وخيمة من كوفيد-19.هدفت هذه الدراسة إلى دراسة خطر الوفاة الناجمة عن الإصابة بكوفيد-19 لدى المرضى المصابين بالنمط 2 من السكري، والتأثير الإضافي لارتفاع ضغط الدم والسمنة لدى السكان الإيرانيين.أُجري مسح مقطعي للسجل الوطني الخاص بمرض كوفيد-19 في وزارة الصحة الإيرانية. وجرى تحليل الحالة الطبية لعدد 22002 من المرضى المصابين بكوفيد-19 في الفترة بين 1 مارس/ آذار و30 أبريل/ نيسان 2020.كان المرضى المصابون بالنمط 2 من السكري أكثر عرضة للوفاة بنسبة أرجحية 1.67 [فاصل ثقة 95٪: 1.53–1.82، القيمة الاحتمالية0.001]. وكان خطر الوفاة أيضًا أعلى لدى مرضى السكري وارتفاع ضغط الدم، بنسبة أرجحية 1.76 [فاصل ثقة 95٪: 1.56–1.99، القيمة الاحتمالية0.001). وبلغت نسبة أرجحية خطر الوفاة لدى مرضى السكري وارتفاع ضغط الدم والسمنة 1.87 (فاصل ثقة 95٪: 1.35–2.58، القيمة الاحتمالية0.001).يُنبئ كلٌ من النمط 2 من داء السكري وارتفاع ضغط الدم والسمنة بالوفيات لدى المرضى الإيرانيين المصابين بكوفيد-19، وعندما تترافق تلك الأمراض معًا، يزداد خطر وفاة المرضى.Risque de mortalité lié à l'infection par la COVID-19 chez les patients iraniens souffrant de diabète de type 2, d'hypertension et d'obésité.Le diabète sucré et l'hypertension sont très prévalents chez les patients atteints d'une forme grave de COVID-19.Étudier le risque de mortalité lié à l'infection par la COVID-19 chez les patients atteints de diabète de type 2 et l'effet additif de l'hypertension et de l'obésité dans la population iranienne.Il s'agissait d'une enquête transversale du registre national de la COVID-19 du ministère iranien de la Santé et de l'Éducation médicale. L'état de santé de 22 002 patients atteints de COVID-19 entre le 1Les patients atteints de diabète de type 2 présentaient un risque de mortalité plus élevé avec un odds ratio (OR) de 1,67 [intervalle de confiance (IC) à 95 % : 1,53-1,82, p0,001]. Le risque de mortalité était également plus élevé chez les patients diabétiques et hypertendus, avec un OR de 1,76 (IC à 95 % : 1,56-1,99, p0,001). L'odds ratio du risque de mortalité chez les patients diabétiques, hypertendus et obèses était de 1,87 (IC à 95 % : 1,35-2,58, p0,001).Le diabète de type 2, l'hypertension et l'obésité permettent respectivement de prédire la mortalité chez les patients iraniens atteints de COVID-19, et lorsqu'ils sont présents ensemble, les patients ont un risque de mortalité plus élevé.
Published: 2022

4. Ross Operation in Neonates: A Meta-analysis

Author: Suyog Mokashi, Andres Zorrilla-Vaca, Taufiek Konrad Rajab, Sandeep Sainathan, and Minoo N. Kavarana
Subjects: Pulmonary and Respiratory Medicine, medicine.medical_specialty, Pediatrics, Heart Valve Diseases, MEDLINE, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Aortic valve replacement, medicine, Humans, Heart Valve Prosthesis Implantation, business.industry, Mortality rate, Incidence (epidemiology), Infant, Newborn, Publication bias, medicine.disease, Confidence interval, Cardiac surgery, Treatment Outcome, 030228 respiratory system, Aortic Valve, Heart Valve Prosthesis, Meta-analysis, Surgery, Cardiology and Cardiovascular Medicine, business
Abstract: Background The Ross operation is the preferred treatment for aortic valve replacement in children. However previous studies indicate that outcomes in neonates are poor. This meta-analysis examines the pooled outcomes of the Ross operation in neonates. Methods Four major databases (PubMed/MEDLINE, EMBASE, Scopus, and ScienceDirect) were searched from inception until May 1, 2020 for studies describing outcomes of the Ross operation in neonates. The primary outcome was early mortality, and secondary outcomes were late mortality and mechanical support. Random-effects models were used to account for possible heterogeneity between studies, and continuity corrections were used to include zero total event trials. Results Eighteen studies comprising outcomes data on 181 neonates were included in the analysis. Meta-analysis showed a pooled early mortality rate of 24% (95% confidence interval, 12%-38%; I2 = 52%, P for heterogeneity = .01). Meta-regression analysis showed that more recently published studies reported significantly worse early mortality (P = .03). The pooled incidence of postoperative mechanical support was 15% (95% confidence interval, 5%-28%; I2 = 28%, P for heterogeneity = .22). No evidence of publication bias was found according to Egger’s test (bias coefficient = 0.21, P = .57). Conclusions The neonatal Ross operation carries a high early mortality rate. The treatment of unrepairable aortic valves in neonates remains an unsolved problem in congenital cardiac surgery.
Published: 2022

5. Pentalogy of Cantrell With a Left Ventricular Diverticulum and Muscular VSD

Author: Morgan Ashley Hill, Jennie H. Kwon, T. Konrad Rajab, and Minoo N. Kavarana
Subjects: Pulmonary and Respiratory Medicine, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, business.industry, Diaphragmatic breathing, medicine.disease, Diaphragm (structural system), Pentalogy of Cantrell, Abdominal wall, medicine.anatomical_structure, Internal medicine, cardiovascular system, medicine, Cardiology, Pericardium, Surgery, cardiovascular diseases, Cardiology and Cardiovascular Medicine, business, Diverticulum, Tetralogy of Fallot, Congenital disorder
Abstract: Pentalogy of Cantrell (POC) is a rare congenital disorder characterized by defects of the anterior diaphragm, midline supraumbilical abdominal wall, diaphragmatic pericardium, lower sternum, and heart. The low incidence and significant heterogeneity of POC make it difficult for most surgeons to gain consistent experience in treating these congenital heart defects. Here we describe the treatment of a patient with POC, Tetralogy of Fallot, left ventricular (LV) diverticulum, and a muscular ventricular septal defect (VSD). An innovative approach through a left ventricular diverticulotomy was utilized which provided excellent exposure for repair of the muscular VSD.
Published: 2022

6. ROLE OF TECHNICAL AND FUNCTIONAL QUALITY IN ACHIEVING PATIENT SATISFACTION (A STUDY OF OPINIONS OF SAMPLE OF PATIENTS IN MEDICAL CITY HOSPITALS)ESSES IN CHILE: AN APPROACH TO THE EARLY RESULTS OF THE SERCOTEC ARICA BUSINESS CENTER

Author: Qassem N. Alwan and Rasha A. Rajab
Subjects: medicine.medical_specialty, Patient satisfaction, Early results, media_common.quotation_subject, Family medicine, medicine, Sample (statistics), Center (algebra and category theory), Quality (business), General Medicine, Psychology, media_common
Published: 2021

7. Anti-diabetics and antimicrobials: Harmony of mutual interplay

Author: Amr S. Abu Lila, Azza A H Rajab, Wael A H Hegazy, and Hisham A. Abbas
Subjects: Harmony (color), medicine.medical_specialty, business.industry, Antimicrobials, Endocrinology, Diabetes and Metabolism, Diabetes, Anti-virulence, Review, Immune disorders, Anti-diabetics, Internal Medicine, Medicine, business, Intensive care medicine
Abstract: Diabetes is one of the four major non-communicable diseases, and appointed by the world health organization as the seventh leading cause of death worldwide. The scientists have turned over every rock in the corners of medical sciences in order to come up with better understanding and hence more effective treatments of diabetes. The continuous research on the subject has elucidated the role of immune disorders and inflammation as definitive factors in the trajectory of diabetes, assuring that blood glucose adjustments would result in a relief in the systemic stress leading to minimizing inflammation. On a parallel basis, microbial infections usually take advantage of immunity disorders and propagate creating a pro-inflammatory environment, all of which can be reversed by antimicrobial treatment. Standing at the crossroads between diabetes, immunity and infection, we aim in this review at projecting the interplay between immunity and diabetes, shedding the light on the overlapping playgrounds for the activity of some antimicrobial and anti-diabetic agents. Furthermore, we focused on the anti-diabetic drugs that can confer antimicrobial or anti-virulence activities.
Published: 2021

8. History and Mental Status Examination in Primary Care in Saudi Arabia: A Review

Author: Anas Murad Abdou Elrahwan, Eman Ahmed Ensseran, Aiyed Hamoud Alanezi, Ashjan Fouad Gholam, Badriah Helal Alazmi, Yasir Nasser Aloufi, Faisal Suliman Algaows, Hadeer Abdulhamid Rajab, Abdulalziz Otaywi A. Alyazidi, Mohammed Mousa Alammari, and Mohammed Abdullh Mutlaqah
Subjects: medicine.medical_specialty, Mental status examination, medicine.diagnostic_test, business.industry, Family medicine, Medicine, Primary care, business
Abstract: The mental state assessment is an important tool for doctors when determining psychiatric diagnosis. Physicians can better identify and differentiate psychiatric diseases if they are familiar with the components of the examination. A thorough medical history entails a more in-depth investigation into the patient's medical problems, including all diseases and illnesses that are currently being treated, as well as those that have left any lasting consequences on the patient's health. A major source of worry is the patient's health literacy, as well as how questions to acquire histories are asked in such a way that the patient understands and can respond appropriately. Medical record practices have a long history of criticism, despite their usefulness. Records that are untimed or outdated, use imprecise language or are illegible, lack a logical structure, are poorly synthesized, are difficult to access and prone to loss, lack information relevant to clinical treatment goals, or are plain incorrect are all common concerns. In this review we will be looking at approaches for mental and history examination, as well as the importance of such reports.
Published: 2021

9. Adhesion barriers in cardiac surgery: A systematic review of efficacy

Author: Morgan Ashley Hill, William T Head, Namrata Paladugu, Brielle Gerry, Jennie H. Kwon, Taufiek Konrad Rajab, Minoo N. Kavarana, and Emily Brennan
Subjects: Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, Adhesion (medicine), Tissue Adhesions, Adhesion barrier, medicine.disease, Cardiac surgery, Postoperative Complications, Reporting bias, medicine, Humans, Surgery, Cardiac Surgical Procedures, Cardiology and Cardiovascular Medicine, Intensive care medicine, business, Formation rate, Pericardium, Polytetrafluoroethylene
Abstract: BACKGROUND Postoperative pericardial adhesions have been associated with increased morbidity, mortality, and surgical difficulty. Barriers exist to limit adhesion formation, yet little is known about their use in cardiac surgery. The study presented here provides the first major systematic review of adhesion barriers in cardiac surgery. METHODS Scopus and PubMed were assessed on November 20, 2020. Inclusion criteria were clinical studies on human subjects, and exclusion criteria were studies not published in English and case reports. Risk of bias was evaluated with the Cochrane Risk of Bias Tool. Barrier efficacy data was assessed with Excel and GraphPad Prism 5. RESULTS Twenty-five studies were identified with a total of 13 barriers and 2928 patients. Polytetrafluoroethylene (PTFE) was the most frequently evaluated barrier (13 studies, 67% of patients) with adhesion formation rate of 37.31% and standardized tenacity score of 26.50. Several barriers had improved efficacy. In particular, Cova CARD had a standardized tenacity score of 15.00. CONCLUSIONS Overall, the data varied considerably in terms of study design and reporting bias. The amount of data was also limited for the non-PTFE studies. PTFE has historically been effective in preventing adhesions. More recent barriers may be superior, yet the current data is nonconfirmatory. No ideal adhesion barrier currently exists, and future barriers must focus on the requirements unique to operating in and around the heart.
Published: 2021

10. Anti-Inflammatory Drugs and Usage of Them among Saudi Population: Knowledge and Attitude Assessment

Author: Muteb A. Aldajam, Fadiyah D. Alanazi, Khames T. Alzahrani, Muhannad A. Almohaimeed, Khalid Abdullah Algamdi, Rasha S. Alshammari, and Alya M. Rajab
Subjects: medicine.medical_specialty, education.field_of_study, Data collection, business.industry, Population, Pharmacist, Sample size determination, Informed consent, Family medicine, Medicine, Observational study, Confidentiality, Medical prescription, business, education
Abstract: Aims: To measure knowledge and attitude among the Saudi population about non-steroidal inflammatory drugs. Study Design: This is an observational cross-sectional study. Place and Duration of Study: Conducted in the north region of Saudi Arabia between June 2020 and July 2021. Methodology: The data collection done by using an electronic questionnaire. Total sample size of 1018 participants, aged between 15-60, Female and Male, agree to participate. Each person meeting the inclusion criteria was provided informed consent, explaining the study aim, and ensuring the confidentiality of information. Data were obtained by filling out the designed Questionnaire. Results: A total of 1018 participants completed the survey questionnaire. About 81% of the study participants stated that they have a history of analgesic use without physician prescription in the past six months. More than 30% of participants stated that the pharmacist is the frequent source of recommendation about medication. The most common indication for the participants to use analgesia was headache followed by insomnia. Conclusion: The awareness and attitude of the participants to NSAIDs' usage and its complications was not that adequate. Paracetamol was the most usually used analgesic. It must to teach and strengthen the awareness among citizens about the proper method to use NSAIDs.
Published: 2021

11. Cerebrospinal Fluid Amyloid Beta, Tau Levels, Apolipoprotein, and 1H-MRS Brain Metabolites in Alzheimer's Disease: A Systematic Review

Author: Fadilah Rajab, Subapriya Suppiah, Mazlyfarina Mohamad, and Albert Dayor Piersson
Subjects: Apolipoprotein E, medicine.medical_specialty, Apolipoprotein B, Amyloid beta, Metabolite, Creatine, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cerebrospinal fluid, Neurochemical, Internal medicine, mental disorders, medicine, Choline, Radiology, Nuclear Medicine and imaging, biology, business.industry, nervous system diseases, Endocrinology, nervous system, chemistry, 030220 oncology & carcinogenesis, biology.protein, business
Abstract: Background There is compelling evidence that neurochemical changes measured by proton magnetic resonance spectroscopy (1H-MRS) occur at different phases of Alzheimer's disease (AD). However, the extent to which these neurochemical changes are associated with validated AD biomarkers and/or apolipoprotein (APOE) e4 is yet to be established. Objective This systematic review analyzed the available evidence on (1) neurochemical changes; and (2) the relations between brain metabolite and validated cerebrospinal fluid biomarkers, and/or APOE in AD. Methods PubMed, Cochrane, Scopus, and gray literature were systematically screened for studies deemed fit for the purpose of the current systematic review. Results Twenty four articles met the inclusion criteria. Decreased levels of N-acetyl aspartate (NAA), NAA/(creatine) Cr, and NAA/(myo-inositol) ml, and increased ml, ml/Cr, Cho (choline)/Cr, and ml/NAA were found in the posterior cingulate cortex/precuneus. Increased ml is associated with increased tau levels, reduced NAA/Cr is associated with increased tau. ml/Cr is negatively correlated with Aβ42, and ml/Cr is positively correlated with t-tau. NAA and glutathione levels are reduced in APOE e4 carriers. APOE e4 exerts no modulatory effect on NAA/Cr. There is interaction between APOE e4, Aβ42, and ml/Cr. Conclusion NAA, ml, NAA/Cr, NAA/ml and ml/Cr may be potentially useful biomarkers that may highlight functional changes in the clinical stages of AD. The combinations of ml and tau, NAA/Cr and Aβ42, and NAA/Cr and tau may support the diagnostic process of differentiating MCI/AD from healthy individuals. Large, longitudinal studies are required to clarify the effect of APOE e4 on brain metabolites.
Published: 2021

12. Higher levels of lead and aluminium are associated with increased risk of falls among community‐dwelling older adults: An 18‐month follow‐up study

Author: Razinah Sharif, Nor Fadilah Rajab, Suzana Shahar, Devinder Kaur Ajit Singh, and Theng Choon Ooi
Subjects: medicine.medical_specialty, business.industry, Incidence (epidemiology), Odds ratio, Logistic regression, Malondialdehyde, Confidence interval, chemistry.chemical_compound, chemistry, Ageing, Internal medicine, Medicine, Lead (electronics), business, Cohort study
Abstract: AIM The present study aims to determine the association of trace elements and oxidative and DNA damage biomarkers with fall incidence among community-dwelling older adults. METHODS This study is part of the Long-term Research Grant Scheme - Towards Useful Ageing cohort study in Malaysia. Of a total of 174 participants with complete trace elements and oxidative and DNA damage data during baseline, only 147 (84.5%) were successfully followed up after 18 months. Participants who experienced any fall events in the previous 18 months during the follow-up were categorized as fallers. RESULTS Thirty participants (20.4%) reported at least one fall in the previous 18 months. The mean concentrations of aluminium, lead and zinc were significantly higher (P
Published: 2021

13. Gain in growth after surgical repair of congenital heart disease among children with Down syndrome

Author: Bana Nasser Agha, Abdulrahman Almazrou, Baraa Tarek Ziad Oubaied, Nazmus Saquib, Juliann Saquib, Jesmin Hossain, Ahmad Mamoun Rajab, and Anas Naser Al Sarraj
Subjects: Heart Defects, Congenital, Male, Pediatrics, medicine.medical_specialty, Down syndrome, Younger age, Heart disease, business.industry, Medical record, Saudi Arabia, Genetic disorder, Infant, Repeated measures design, medicine.disease, Body Height, Body Mass Index, Genetics, medicine, Humans, Analysis of variance, Down Syndrome, Child, business, Body mass index, Genetics (clinical)
Abstract: Down syndrome (DS) is a common genetic disorder among Saudi children, for which limited data is available on growth for those who undergo surgery for congenital heart disease (CHD). We assessed the magnitude of growth over time following surgery and the factors associated with growth change. Eighty-eight children with DS and CHD who underwent surgery between 2009 and 2017 at the tertiary children's hospital in Al-Qassim, Saudi Arabia, were eligible. Information on gender, height, and weight (at surgery, 6 and 12 months), age at surgery, and type of CHD were abstracted from the medical records. Repeated measure analysis of variance (ANOVA) was used for data analysis. The sample's mean age (SD) was 16.2 months (20.1); 47% were male. Height, weight, and body mass index (BMI) increased significantly at both follow-up points. There was a significant interaction between age at surgery, type of heart disease, and time for all three physical indices (p-values0.001). The increase in height, weight, and BMI was significantly greater for children ≤8 months old with acyanotic CHD compared to children8 months with cyanotic CHD. Overall, the gain in growth was greater for the children with DS who had had surgery at a younger age.
Published: 2021

14. Barriers to initiation of insulin therapy in poorly controlled type 2 diabetes based on self-determination theory

Author: Soghra Rabizadeh, Salome Sadat Salehi, Pegah Khaloo, Alireza Esteghamati, Manouchehr Nakhjavani, Armin Rajab, Reza Majdzadeh, Hossein Mirmiranpour, Hamid Alemi, and Assadollah Rajab
Subjects: medicine.medical_specialty, business.industry, Insulin, medicine.medical_treatment, General Medicine, Type 2 diabetes, medicine.disease, Diabetes Mellitus, Type 2, Slow progression, Surveys and Questionnaires, Diabetes mellitus, Internal medicine, Personal Autonomy, Severity of illness, medicine, Humans, Patient Compliance, Intrinsic motivation, Medical prescription, business, Self-determination theory
Abstract: Proper glycaemic control can slow progression of diabetes complications. One of the main causes of poor glycaemic control is delayed initiation of insulin therapy.To explain the reasons for delayed insulin initiation based on a behavioural model using patients' innate psychological needs.We enrolled 151 patients with type 2 diabetes who had indications for insulin therapy. Thirty general practitioners (GPs) were included as care providers. Patients were studied by questionnaires evaluating components of self determination theory, such as competency, relatedness and autonomy. We also evaluated patients' attitudes towards insulin therapy using the Insulin Treatment Appraisal Scale questionnaire. GPs' attitudes towards insulin therapy were assessed with a different questionnaire.Competency of patients was scored as acceptable (14.44/20). Relatedness score was low at around 15.63/30. The findings suggested that the patients' intrinsic motivation was less than their extrinsic motivation (8.41/15 vs 15.03/20). The main barrier to insulin therapy on the patients' side was rejection of severity of illness (67.5%). According to GPs, low compliance (96.7%) was the main cause of delayed insulin prescription.We observed that patients do not have a proper understanding about their illness. Due to the low score of relatedness as a representative of patients and care providers' relationship, we highlight the importance of educating both about insulin therapy and how they can have the most effective relationship in this process.العوائق التي تَُول دون بدء العلاج بالأنسولين لداء السُّكَّري من النمط الثاني الذي لا يمكن ضبطه جيداً استناداً إلى نظرية تقرير المصير.أرمين رجب، بيجا خالو، صغرى رابي زاده، حميد العليمي، سالومي صالحي، رضا مجدزاده، حسين ميرميرانبور، أسد الله رجب، علي رضا إستغاماتي، منوچهر نخجواني.يمكن أن يؤدي ضبط سكر الدم على نحوٍ صحيح إلى إبطاء تفاقم مضاعفات السُّكَّري. ويُعد تأخر بدء العلاج بالأنسولين أحد الأسباب الرئيسية التي تحول دون الضبط الجيد لسكر الدم.هدفت هذه الدراسة إلى شرح أسباب تأخُّر بدء العلاج بالأنسولين بِناءً على نموذج سلوكي يستند إلى احتياجات المرضى النفسية الفطرية.شملت هذه الدراسة 151 مريضاً بالسُّكَّري من النمط الثاني تستدعي حالاتهم العلاج بالأنسولين. وشملت ثلاثين ممارساً عاماً يضطلعون بدور مُقدِّمي خدمات الرعاية. وخضع المرضى للدراسة عن طريق استبيانات لتقييم مكوِّنات نظرية تقرير المصير، مثل الكفاءة والارتباط والاستقلالية. كما أجرينا تقييماً لمواقف المرضى تجاه العلاج بالأنسولين باستخدام استبيان مقياس تقييم العلاج بالأنسولين. وقُيّمَت مواقف الممارسين العامِّين تجاه العلاج بالأنسولين باستخدام استبيان مختلف.حصلت كفاءة المرضى على درجة مقبولة (14.44 / 20)، فيما حصل الارتباط على درجة منخفضة تُقدَّر بنحو 15.63 / 30. وأشارت النتائج إلى أن الدافع الذاتي للمرضى كان أقلَّ من دوافعهم الخارجية (8.41 / 15 مقابل 15.03 / 20). وتَثَّل العائق الرئيسي الذي يحُول دون إقدام المرضى على العلاج بالأنسولين في عدم الاعتراف بشدة المرض (67.5٪). ووَفْقاً للممارسين العامِّين، كان انخفاض الامتثال (96.7٪) السبب الرئيسي لتأخُّر وصف الأنسولين.لاحظنا أن المرضى لا يتمتعون بفهمٍ صحيحٍ لمرضهم. ونظراً لانخفاض درجة الارتباط كممثل للعلاقة بين المرضى ومُقدِّمي خدمات الرعاية، فإننا نُسلّط الضوءَ على أهمية تثقيف كلٍ منهما بشأن العلاج بالأنسولين، وكيف يمكن الوصول إلى أفضل علاقة فعّالة بين الطرفين في إطار هذه العملية.Obstacles face à la mise en place de l’insulinothérapie dans le diabète de type 2 mal contrôlé selon la théorie de l’autodétermination.Un contrôle adéquat de la glycémie permet de ralentir la progression des complications du diabète. Le retard dans la mise en place de l’insulinothérapie constitue l’une des principales causes d’un mauvais contrôle de la glycémie.Expliquer les raisons du retard de la mise en place du traitement par insuline sur la base d’un modèle comportemental fondé sur les besoins psychologiques innés des patients.Nous avons recruté 151 patients atteints de diabète de type 2 pour lesquels l’insulinothérapie était indiquée. Une trentaine de médecins généralistes ont été inclus en qualité de prestataires de soins. L’étude a été menée au moyen de questionnaires évaluant des composantes de la théorie de l’autodétermination, telles que la compétence, l’affiliation et l’autonomie. Nous avons également évalué les attitudes des patients vis-à-vis de l’insulinothérapie à l’aide du questionnaire de l’échelle d’évaluation de l’insulinothérapie (Insulin Treatment Appraisal Scale). Les attitudes des médecins généralistes vis-à-vis de l’insulinothérapie ont été évaluées au moyen d’un questionnaire différent.La compétence des patients a été jugée acceptable (14,44/20). Le score se rapportant à l’affiliation était faible, à environ 15,63/30. Les résultats suggèrent que la motivation intrinsèque des patients était inférieure à leur motivation extrinsèque (8,41/15 contre 15,03/20). Du côté des patients, le rejet de la gravité de la maladie (67,5 %) constituait le principal obstacle à la mise en place de l’insulinothérapie. Selon les médecins généralistes, une faible observance (96,7 %) était la principale cause de retard dans la prescription d’insuline.Nous avons observé que les patients ont une mauvaise compréhension de leur maladie. En raison de la faiblesse du score concernant l’affiliation, en tant qu’élément représentant la relation entre les patients et les prestataires de soins, nous soulignons l’importance d’une meilleure sensibilisation des malades et soignants à l’insulinothérapie et de la manière de mettre en place une relation efficace.
Published: 2020

15. Methicillin-resistant Staphylococcus aureus development in intensive care patients

Author: Saed Enabi, Amjad Chamsi Basha, Mohamed Abdelghafour Ali, Ahmad Mamoun Rajab, Tawfik Mamoun Rajab, Nazmus Saquib, Ahmed Abdelgadir, Saleh Qusai Saleh Ayash, and Abdullah Murhaf Al-Khani
Subjects: medicine.medical_specialty, business.industry, Case-control study, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, medicine.disease_cause, Intensive care unit, Comorbidity, Methicillin-resistant Staphylococcus aureus, law.invention, Sepsis, 03 medical and health sciences, 0302 clinical medicine, Staphylococcus aureus, law, Internal medicine, Intensive care, Hospital-acquired infection, medicine, 030212 general & internal medicine, business
Abstract: Objectives : To determine the factors associated with the development of methicillin-resistant Staphylococcus aureus (MRSA), hospital stay and mortality, and early versus late MRSA infection. Methods : Cases (n=44) were intensive care unit (ICU) patients admitted to King Fahd Specialist Hospital, Al-Qassim, Saudi Arabia between 2015 and 2019 who developed MRSA during their hospital stay. Controls (n=48) were patients from the same place and period who did not develop MRSA. Data were abstracted from hospital records. Results : Admission with sepsis (case: 46% vs. control: 2%, p less than 0.001) and having at least one comorbid condition (case: 95% vs. control: 46%, p less than 0.001) were significantly associated with the development of MRSA. Age (mean ±SD: case: 65±18, control: 64±18, p=0.7) and gender (% male, case: 52%, control: 56%, p=0.70) were not associated with the development of MRSA. Approximately 73% of all MRSA cases developed within the first 2 weeks of admission. Among the early cases, 44% died during their ICU stay; the corresponding percentage among the late cases was 42% (p=0.69). There was no difference between early and late MRSA cases in terms of non-sepsis admissions (50% vs. 67%, p=0.32) or comorbid status (at least one: 97% vs. 92%, p=0.17). Conclusion : Sepsis and comorbid conditions were significant risk factors for MRSA development among hospital patients. Saudi Med J 2020; Vol. 41 (11): 1181-1186 doi: 10.15537/smj.2020.11.25465 How to cite this article: Ali MA, Rajab AM, Al-Khani AM, Ayash SQ, Basha AC, Abdelgadir A, Rajab TM, Enabi S, Saquib N. Methicillin-resistant Staphylococcus aureus development in intensive care patients. A case-control study. Saudi Med J. 2020 Nov;41(11):1181-1186. doi: 10.15537/smj.2020.11.25465.
Published: 2020

16. Immunohistochemical Expression of Retinoblastoma Gene Product and p53 Protein in Transitional Cell Carcinoma of the Urinary Bladder and its Relationship to Different Clinicopathological Parameters

Author: Zina A. Rajab Alhamadani, Alaa Qasim Yahya, and Mohanad Mundher
Subjects: medicine.medical_specialty, Bladder cancer, Urinary bladder, business.industry, Urinary system, medicine.medical_treatment, H&E stain, General Medicine, medicine.disease, Gastroenterology, Cystectomy, Transitional cell carcinoma, medicine.anatomical_structure, Internal medicine, Carcinoma, medicine, Bladder stones, business
Abstract: BACKGROUND: Carcinoma of urinary bladder is one of the most common malignancies worldwide and constitutes a major health problem. Multiple risk factors are associated with this tumor and its prognosis will depend on different clinicopathological parameters. Over expression of P53 protein and mutant Rb gene is associated with more aggressive clinical and histopathological features of the tumor such as advanced stage and higher grade. AIM: The immunohistochemical expression of Rb gene and P53 gene will be assessed through their protein products in transitional cell carcinoma (TCC) of the urinary bladder and then will be correlated with other well-known risk factors and prognostic parameters of bladder TCC, such as grading, tumor size, smoking, alcohol drinking, and family history. METHODS: Patients were recruited from the uro-surgical department/Surgical Subspecialties Teaching Hospital during the period from November 2020 through April 2021. In this study, patients enrolled were those suspected to have bladder carcinoma. The work up included a full history and clinical examination. Surgical samples were taken from the patients for histopathological evaluation; the study’s samples represented either endoscopic cup biopsy, transurethral resection of the tumor, or radical cystectomy. Sections obtained from these samples were stained with the conventional hematoxylin and eosin stain. Then, immunohistochemical staining for P53 and pRB was applied only for patients diagnosed with TCC. RESULTS: The differences between low-grade and high-grade tumors regarding pRb percentage score were statistically significant (p = 0.026), but were not significant regarding the intensity score (p = 0.094). There were significant correlations between tumor stage and both pRb intensity and percentage scores (p = 0.044 and 0.042, respectively). Differences between low-grade and high-grade tumors regarding p53 intensity score were significant (p = 0.022). The differences between low-grade and high-grade tumors regarding p53 percentage score were significant (p = 0.049). The differences between different tumor stages regarding p53 intensity score were significant (p = 0.018). The differences between different tumor stages regarding P53 percentage score were significant (p = 0.019). CONCLUSIONS: Tumor’s grade was found to be correlated with the tumor stage with no correlation with the age, gender, smoking, family history of TCC, history of urinary tract infection, bladder stones, nor the recurrence of the tumor. The pRb intensity and the percentage scores were correlated to each other and to tumor’s grade and stage, except for the pRb intensity which showed no correlation with the tumor’s grade. The P53 intensity and percentage scores were correlated to each other and also to tumor’s grade and stage, so that P53 is over-expressed in tumors with higher grade and stage.
Published: 2021

17. Study of Walnut Oil Supplementation on Serum Biochemical Parameters and Histopathology of Male Rats

Author: Ali Abbas Abo Ajon, Hayder Hasan Rajab, Mohammed Zuheir Hassan, Hussein Raof Al Ghazali, Ashraf Raoof Mohammed Ali, and Mohammed Jaffer Al Anssari
Subjects: medicine.medical_specialty, Developmental Neuroscience, Cognitive Neuroscience, Male rats, medicine, Physiology, Histopathology, Walnut oil, Biology, Atomic and Molecular Physics, and Optics
Abstract: The purpose of the experiment is an investigate the association of walnut oil with lipid profiles, glucose as well as total proteins and assessment its side effect on some sensitive organs such as the liver and spleen tissues. The experiment divided into two main groups are treated group with walnut oil and the control group, where the former divided into two subgroups 0.25 and 0.5 ml of oil per each. We found a statistically non-significant difference between treated and control groups (for total protein, lipid profile, and glucose). There was no change in total protein, but cholesterol decreased by 0.25 ml but a little increased by 0.5 ml. HDL was increased for the treated group. While on 0.25 ml LDL decreased in treated animals, on another hand no change for 0.5 ml. Also, no change for VLDL between treated and control. The only triglyceride was increased but non-significant for the treated group compared with the control. Both doses decreased in treated animals for glucose. We also found an increase in whole-body weight and on sensitive organs such as the liver and spleen. Even no change in a histological study for the mentioned organs. The conclusion: By walnut oil, all parameters have changed despite the treated group was normal without any induced diseases. So, recommended the researchers induce the disorders in the liver and assessment the extracted oil on the lipid profile.
Published: 2021

18. Native Aortic Root Thrombosis After Norwood Palliation for Hypoplastic Left Heart Syndrome

Author: Taufiek Konrad Rajab and Max B. Mitchell
Subjects: Pulmonary and Respiratory Medicine, medicine.medical_specialty, business.industry, medicine.medical_treatment, Thrombolysis, 030204 cardiovascular system & hematology, medicine.disease, Thrombosis, Surgery, Hypoplastic left heart syndrome, 03 medical and health sciences, Catheter, 0302 clinical medicine, 030228 respiratory system, medicine, Retrograde perfusion, Stage (cooking), Cardiology and Cardiovascular Medicine, business, Complication, Cardiac catheterization
Abstract: Background Norwood palliation for hypoplastic left heart syndrome typically results in retrograde perfusion of the native aortic root. This may predispose to native aortic root thrombosis (NART). Methods Patients who underwent stage 1 Norwood palliation at Children’s Hospital Colorado between 2003 and 2019 were retrospectively reviewed for NART. Additional patients were identified by a systematic literature review. Patient factors, operative details, presentation, diagnostic methods, treatments, and outcomes were analyzed. Results Three patients with NART were identified among 241 patients who had undergone stage 1 Norwood palliation at Children’s Hospital Colorado (mean follow-up, 48 months). A fourth patient identified at Children’s Hospital Colorado had undergone stage 1 palliation elsewhere. The systematic literature review identified 12 additional patients. Among the 16 patients, patients presented with new arrhythmias (38% [n = 6]), evidence of ischemia (31% [n = 5]), incidentally (19% [n = 3]), inability to wean from postoperative support (6% [n = 1]), and cardiac arrest (6% [n = 1). The diagnosis was made by transthoracic echocardiography (TTE) in 50% (n = 8), transesophageal echocardiography in 19% (n = 3), cardiac catheterization in 25% (n = 4), and cardiac computed tomography in 6% (n = 1). Importantly, 44% (n = 7) of patients were missed by TTE and subsequently diagnosed by other methods. Treatment strategies were surgical thrombectomy in 38% (n = 6), anticoagulation alone in 38% (n = 6), direct catheter thrombolysis in 19% (n = 3), and systemic thrombolysis in 6% (n = 1). The rate of mortality or transplant listing was 44% (n = 7). Conclusions NART is an underappreciated complication of Norwood palliation with high mortality. There should be a high index of suspicion for NART in patients after Norwood palliation with an unexplained complicated clinical course. Importantly, NART is frequently missed by TTE.
Published: 2021

19. Topographical patterns of whole-brain structural alterations in association with genetic risk, cerebrospinal fluid, positron emission tomography biomarkers of Alzheimer’s disease, and neuropsychological measures

Author: Subapriya Suppiah, Mazlyfarina Mohamad, Albert Dayor Piersson, and Nor Fadilah Rajab
Subjects: Apolipoprotein E, Oncology, medicine.medical_specialty, biology, medicine.diagnostic_test, business.industry, Tau protein, Neuropsychology, medicine.disease, Temporal lobe, Cerebrospinal fluid, Atrophy, Positron emission tomography, Internal medicine, biology.protein, Medicine, Radiology, Nuclear Medicine and imaging, business, Episodic memory
Abstract: This study aimed at investigating the topographical pattern of whole-brain structural alterations in association with apolipoprotein E e4 (APOE e4), cerebrospinal fluid (CSF) [amyloid-beta 42 (Aβ42), and neurofibrillary tau protein], positron emission tomography (PET) biomarkers [Aβ, tau, and 2-[18F]fluoro-2-deoxy-d-glucose (FDG)], and neuropsychological measures. PubMed, Scopus, Ovid, and Cochrane databases were searched. Risk of bias (using a modified Newcastle–Ottawa Scale) and level of evidence were determined. One hundred and thirty-one studies met the inclusion criteria. APOE e4 effect is exerted on the whole-brain. Still, the medial temporal lobe is the most affected, with moderate evidence observed across the lifespan (except late mid-life) and in the AD continuum. Moderate to strong evidence shows that atrophy of AD-vulnerable regions is associated with reduced CSF Aβ42, increased Aβ- and tau-PET, and increased CSF tau. No association between gray matter changes and FDG-PET measures in healthy late mid-life and older adults. Preliminary findings demonstrate a relationship between hippocampal atrophy and lower episodic memory in early life. Moderate evidence of an association between hippocampal atrophy and lower episodic memory is observed in late mid-life. In contrast, hippocampal atrophy is associated with reduced episodic memory and global cognition in older APOE e4 carriers. Strong evidence suggests that atrophy of the AD vulnerable regions is associated with CSF and PET biomarkers and cognitive measures. These relationships may be potentially helpful in characterizing the preclinical and clinical stages of MCI and AD and predicting AD progression.
Published: 2021

20. Switching of Hashimoto Thyroiditis Into Graves’ Disease: A Case Report and Literature Review

Author: Nour Maksoud, Lubana Wannous, Rajab Maksoud, and Samaher Almousa
Subjects: hashimoto thyroiditis, endocrine system, medicine.medical_specialty, Goiter, endocrine system diseases, Graves' disease, Levothyroxine, Physical examination, Gastroenterology, Lethargy, Thyroid peroxidase, Internal medicine, medicine, autoimmune diseases, biology, medicine.diagnostic_test, business.industry, Thyroid, medicine.disease, graves disease, medicine.anatomical_structure, biology.protein, Medicine, business, Hormone, medicine.drug
Abstract: Background: Hashimoto thyroiditis (HT) and Graves’ disease (GD) are autoimmune inflammatory thyroid disorders. The evolution from GD into HT is the most common scenario while the conversion from HT into GD seems to be less common. Case Presentation: A 20-year-old female patient referred to the endocrinology clinic with a three-month history of fatigue, lethargy, lack of appetite, constipation, menorrhagia, cold intolerance, and 5 kg weight gain in the last two months. Clinical examination showed dry skin, scalp hair loss, and painless hard goiter whereas thyroid ultrasound revealed generalized homogeneous hypoechoic thyroid hypertrophy. Laboratory tests demonstrated increased serum thyroid-stimulating hormone (TSH) 210 µIU/L (normal: 0.25-4.50), decreased free thyroxine (FT4) 0.37 ng/L (normal: 0.8-1.8) and free triiodothyronine (FT3) 1.94 pg/mL (normal: 1.8-4.6), and finally, increased thyroid peroxidase antibodies (anti-TPO) 462 IU/mL (normal: up to 34). Based on observations, HT was diagnosed and thus daily treatment with levothyroxine 75 mcg was started for the patient. Two months later, she referred with symptoms suggestive of hyperthyroidism with reduced TSH levels, which did not improve after levothyroxine cessation, thus more laboratory tests were conducted and revealed decreased TSH levels, increased T3 and T4, and TSH receptor stimulating antibody (TSAb)levels, and increased radioactive iodine uptake at 24 hours. Therefore, the diagnosis of GD was made. Five weeks after treatment, she was in full remission. Conclusion: Although the switch from HT into GD is rare, it can occur at any time during the disease. Nonetheless, early diagnosis and treatment would improve the quality of care.
Published: 2021

21. Neuroimaging Functional Magnetic Resonance Imaging Task‐Based Dorsolateral Prefrontal Cortex Activation Following 12 Weeks of <scp> Cosmos caudatus </scp> Supplementation Among Older Adults With Mild Cognitive Impairment

Author: Yee Xing You, Suzana Shahar, Nor Fadilah Rajab, Hamzaini Abdul Hamid, Normah Che Din, Mazlyfarina Mohamad, and Hasnah Haron
Subjects: education.field_of_study, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Working memory, Population, Neuropsychology, Audiology, Southeast asian, 030218 nuclear medicine & medical imaging, Dorsolateral prefrontal cortex, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, medicine, Memory span, Radiology, Nuclear Medicine and imaging, Functional magnetic resonance imaging, education, business, Anterior cingulate cortex
Abstract: BACKGROUND Cosmos caudatus (CC) is traditional Asian vegetable, commonly consumed among the Southeast Asian population. It has been reported to be high in flavonoids and might potentially improve brain activity among older adults with mild cognitive impairment (MCI). The effect of CC in brain activation improvement using neuroimaging is yet to be discovered. PURPOSE To investigate the effects of CC supplement on brain activity using functional magnetic resonance imaging (fMRI) among older adults with MCI. STUDY TYPE Prospective, randomized, double-blind, placebo-controlled trial. POPULATION/SUBJECTS Twenty older adults with mild cognitive impairment (60-75 years old), 14 of them (70%) were female subjects. FIELD STRENGTH/SEQUENCE A 3.0-T, T1-weighted anatomical images, T2*-weighted imaging data, A single shot, gradient echo-echo planar imaging (EPI) sequence. ASSESSMENT All subjects were asked to consume two 500 mg capsules of either CC supplement or placebo (maltodextrin) daily for 12 weeks. Cognitive function was measured using validated neuropsychological tests (i.e. Mini-mental State Examination and Digit Span) and task-based fMRI (N-back and Stroop Color Word Test) at baseline and 12th week. Brodmann's area 9, 46 and anterior cingulate cortex were selected as the regions of interest to define dorsolateral prefrontal cortex (DLPFC) in fMRI analysis. STATISTICAL TESTS Normality test was performed with the Shapiro-Wilk test. Two-way repeated ANOVA determined the intervention effects of the CC supplementation on brain activity after adjustments for covariates. Significance level at P
Published: 2021

22. Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries

Author: Stephen R Knight, Catherine A Shaw, Riinu Pius, Thomas M Drake, Lisa Norman, Adesoji O Ademuyiwa, Adewale O Adisa, Maria Lorena Aguilera, Sara W Al-Saqqa, Ibrahim Al-Slaibi, Aneel Bhangu, Bruce M Biccard, Peter Brocklehurst, Ainhoa Costas-Chavarri, Kathryn Chu, Anna Dare, Muhammed Elhadi, Cameron J Fairfield, J Edward Fitzgerald, Dhruv Ghosh, James Glasbey, Mark I. van Berge Henegouwen, J.C. Allen Ingabire, T Peter Kingham, Marie Carmela Lapitan, Ismaïl Lawani, Bettina Lieske, Richard Lilford, Janet Martin, Kenneth A McLean, Rachel Moore, Dion Morton, Dmitri Nepogodiev, Faustin Ntirenganya, Francesco Pata, Thomas Pinkney, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Aya Riad, Hosni Khairy Salem, Joana Simões, Richard Spence, Neil Smart, Stephen Tabiri, Hannah Thomas, Thomas G Weiser, Malcolm West, John Whitaker, Ewen M Harrison, Arben Gjata, Maria Marta Modolo, Sebastian King, Erick Chan, Sayeda Nazmun Nahar, Ade Waterman, Dominique Vervoort, Alemayehu Ginbo Bedada, Bernardo De Azevedo, Ana Gabriela Figueiredo, Manol Sokolov, Venerand Barendegere, Gerald Ekwen, Arnav Agarwal, Qinyang Liu, Juan Camilo Correa, Kalisya Luc Malemo, Jacques Bake, Jakov Mihanovic, Kamila Kuncarová, Julius Orhalmi, Hosni Salem, Jyri Teras, Aristotelis Kechagias, Alexis P Arnaud, Judith Lindert, Vasileios Kalles, Maria-Lorena Aguilera-Arevalo, Gustavo Recinos, Zsolt Baranyai, Basant Kumar, Harish Neelamraju Lakshmi, Sanoop Koshy Zachariah, Philip Alexander, Sunil Kumar Venkatappa, C Pramesh, Radhian Amandito, Christina Fleming, Luca Ansaloni, Gianluca Pellino, Ahmed M. Altibi, Ibrahim Nour, Intisar Hamdun, Ali M. Ghellai, Donatas Venskutonis, Tomas Poskus, Justas Zilinskas, Precious Malemia, Yong Yong Tew, Elaine Borg, Sarah Ellul, fatima Zahraa Wafqui, David W Borowski, Anne Sophie van Dalen, Cameron Wells, Harissou Adamou, Adesoji Ademuyiwa, Adewale Adisa, Kjetil Søreide, Sara Al Saqqa, Osaid Alser, Haya Tahboub, Helmut Alfredo Segovia Lohse, Sebastian Shu Yip, Piotr Major, António Sampaio Soares, Matei Razvan Bratu, Andrey Litvin, Armen Vardanyan, JC Allen Ingabire, Ahmad Gudal, Naif Albati, Jovan Juloski, Miran Rems, Sarah Rayne, Stephanie Van Straten, Yoshan Moodley, Irene Ortega Vázquez, Jaime Ruiz-Tovar, Kithsiri Janakantha Senanayake, Sujeewa Priyantha Bandara Thalgaspitiya, Omer Abdelbagi Omer, Anmar Homeida, Yucel Cengiz, Daniel Clerc, Muhammad Alshaar, Hanen Bouaziz, Yuksel Altinel, Matthew Doe, Maryna Freigofer, Ella Teasdale, Rakan Kabariti, Joshua Michael Clements, Stephen Richard Knight, Ahsan Ashfaq, Ijeoma Azodo, Gabriela Wagner, Ivan Trostchansky, Mayaba Maimbo, David Linyama, Helidon Nina, Amanda Zeko, Claudio Gabriel Fermani, Santiago Villalobos, Federico Carballo, Pablo Farina, Sebastian Guckenheimer, Marilla Dickfos, Ankit Ajmera, Chester Chong, Ralph Gourlay, Sikandar Hussaini, Yi Jia Lee, Adeeb Majid, Peter Martin, Rebecca Miles, Owen James Morris, Jamie Phua, William Ridley, Tarunpreet Saluja, Ryan Renxin Tan, Jen Teh, Anna Wells, Bharti Arora, Qaasim Dollie, Debbie Ho, Yanru Ma, Omattage Mahasha Perera, Anthony Truong, Amanda Caroline Dawson, Bryan Lim, Upuli Pahalawatta, Jacqueline Phan, Xiao-Ming Sarah Woon-Shoo-Tong, Andrea Yeoh, Lillian Charman, Andrew Drane, Sharon Laura, Charmaine Chu Wen Lo, Amy Mozes, Rita Poon, Hao Han Tan, Ellen Wall, Prakshi Chopra, Jasmine De Giovanni, Bal Dhital, Brian Draganic, Alexander Duller, Jonathan Gani, Yao Kuan Goh, Jun Young Jeong, Brendan McManus, Prakash Nagappan, Peter Pockney, Anya Rugendyke, Mahsa Sarrami, Stephen Smith, Vanessa Wills, Hsu Ven Wong, Geoffrey Ye, Geoffrey Zhang, Ethan Brooker, Daniel Feng, Bonnie Lau, Carlin Ngai, Sarah Birks, David Gyorki, Jaime Otero de Pablos, Ali Abbosh, Chris Gillespie, Ahmed Mahmoud, Bianca Kwan, Joshua Lawson, Andrea Warwick, Janne Bingham, Andrew J Cockbain, Nagendra Naidu Dudi-Venkata, Jordan Ellaby-Hall, Ben Finlay, Emily Humphries, Jade Pisaniello, Monique Pisaniello, Salma Salih, Tarik Sammour, Haidar Hadri Abd Wahab, April De Silva, Nicola Hayward, Kartik Iyer, Guy Maddern, Gian Andrea Prevost, Naga Annapureddy, Krishna Pranathi Settipalli, Jeremy Yeo, Lucy Hempenstall, Lily Pham, Shaun Purcell, Cherry Talavera, Ashish I Vaska, Gurpreet Chaggar, Phillip Chrapko, Annelise Cocco, Sarah Michelle Crystal Jade Coulter-Nile, Grahame Ctercteko, James French, Houchen Gong, Martijn Gosselink, Thuvarahan Jegathees, Ivan Jin, Michelle Kalachov, Kathryn Kiefhaber, Katherine Lee, Jason Luong, Steven Phan, Henry Pleass, Kelly Veale, Zhi Zeng, Angela Au, Ashe DeBiasio, Idy Deng, Jananee Myooran, Amrita Nair, Peter Stewart, Anton Stift, Lukas Walter Unger, Kerstin Wimmer, Nabila Ahmed, Syed Hasan, Saber Rahman, Margaret O'Shea, Greg Padmore, Adrian Peters, Pietro Perduca, Guenda Pulcina, Nicolas Tinton, Frederic Buxant, Elsa Dabin, Giulia Garofalo, Francis Dossou, Freddy Houehanou Rodrigue Gnangnon, Yacoubou Imorou Souaibou, Pako Motlaleselelo, Omphile Tlhomelang, Igor Lima Buarque, Gustavo Mendonça Ataíde Gomes, Aldo Vieira Barros, Ilia Batashki, Nikolai Damianov, Vladislav Stoyanov, Dragomir Dardanov, Svilen Maslyankov, Plamen Petkov, George Todorov, Evgeni Zhivkov, Aygulya Akisheva, Miguel Angel Castilla Moreno, Geno Genov, Ivelina Ilieva, Tsvetomir Ivanov, Martin Karamanliev, Azhar Khan, Emil Mitkov, Tsanko Yotsov, Boyko Atanasov, Nikolay Belev, Mihail Slavchev, Carlos Nsengiyumva, Elgan Jones, Simon Stock, Steve Kyota, James Brown, Tresor Mabanza K., Lemery Nigo Samuel, Chidi Otuneme, Ngwang Prosper, Franklin Umenze, Marylise Boutros, Natasha Caminsky, Sinziana Dumitra, Richard Garfinkle, Dominique Morency, Ebram Salama, Alexander Banks, Lorenzo Ferri, Haitian He, Amit Katz, Alexander Sender Liberman, Sarkis Meterissian, Allison Pang, Elena Parvez, Usmaan Hameed, Fahima Osman, Sangita Sequeira, Natalie Coburn, Alisha Jaffer, Paul Karanicolas, Matthew Mosseler, Reilly Musselman, Xinyuan Liu, Ching Wan Yip, Juan Sebastian Garces-Otero, Carolina Guzman, Sebastian Sierra, Andres Uribe Valencia, Paulo Andrés Cabrera Rivera, Saul Camelo, Andrea Gonzalez, Alejandro González-Orozco, Manuel Santiago Mosquera Paz, Carlos J- Perez Rivera, Felipe Gonzalez, Andres Isaza-Restrepo, Laura Nino- Torres, Natalia Arias Madrid, Maria Clara Mendoza Arango, Justin Tsandiraki, Damir Jemendžic, Branislav Kocman, Oliver Šuman, Renata Canic, Darko Jurišic, Ivana Karakas, Ana Krizanovic Rupcic, Vlatka Pitlovic, Josip Samardžic, Mario Kopljar, Ivan Bacic, Edgar Domini, Robert Karlo, Danijela Miljanic, Andrea Simic, Mariam Ahmed, Majdi Al Nassrallah, Rabiya Altaf, Talal Amjad, Ruba Eltoum, Heba Haidar, Alhassan Hassan, Omar Khalil, Marwan Qasem, Rommel Ramesh, Gautham Sajith, Maham Wisal, Jan Žatecký, Michele Bujda, Katerina Jirankova, Ales Paclik, Aya Abdallah, Mariam Abdulgawad Almogy, Esraa Ayman El-sawy, Ahmed Moustafa ElFayoumy, Nourhan Elghareeb, Nourhan Ahmed Esmat, Ahmed Fadel, Abdullah Habater, Heba Hamdy, Amr Hefni, Marwa Kamal, Norhan Mohamed Abobakr, Ahmed Sayed, Nancy Shaker, Ehab Taha, Hoda Tharwat, Omar Zakaria, Ibrahem Abdelmotaleb, Ali Al-Dhufri, Hamza S. Al-Himyari, Enas El sheikh, Asmaa Eldmaty, Aya Elkhalawy, Ahmed M.Elkhashen, Kithara Magdy, Safa Mostafa, Habib Doutoum Sadia, Mohamed mahmoud Saleh, Dina Samir, Mohamed Yahia Mohamed Ali, Mahmoud A. Nassar, Samar Abdelhady, Aly Abdelrazek, Israa Abdelsalam, Aya El-Sawy, Eman Essam, Mohamed Gadelkarim, Khaled Ghaly, Mohamed Hassabalnaby, Rana Masarani, Nourhan Mohamed Shaaban, Ahmed Sabry, Menatalla Salem, Nourhan Akram Soliman, Diaaaldin Zahran, Moustafa Ramadan Abou El.soud, Esraa Tarek Badr, Hala Borham, Nehal Elmeslemany, Mohammad Elsayed, Fawzia Elsherif, Sara Eslam, Gehad Gaber, Sondos Ibrahim, Yara Kamh, Abdelrahman Mahmoud, Shimaa gamal Mohamed, Eman Morshedy, Cinderella Omar, Fatima Salem Soliman, Shaza Abdelkawy, Naglaa Abdelmohsen, Mahmoud Abdelshakour, Ahmed Dahy, Norhan Gamal, Mohammed Gamal, Ahmad Hasan, Helal Hetta, Nehad Mousa, Mohamed Omar, Somia Rabie, Mahmoud Saad, Bakeer Saleh, Marwa Sayed Mohamed, Muhammad Shawqi, Heba Abdelhady Mousa, Mostafa Alnoury, Mohamed Elbealawy, Ahmed Elshafey, Muhammad Essam Ibrahim El Desouki Muhammad Ahmed, Mennatullah Ghonaim, Fawzy Hgag, Mohamed Ibrahim, Mahmoud Morsy, Mohamed Reda Loaloa, Ahmed Refaat, Hadeer Samir, Fatma Shahien, Mohamed Sobhy, Fathy Sroor, Esraa Abdellatif, Marina Adel, Amr Abdelghani Afifi, Eman Afifi, Marco Antaky, Amr Dawoud, Naira El Zoghby, Amira El-remaily, Ali Abdelazez Elzanfaly, Ahmed Gadallah, Fatma Alzahraa Gamal, Omar Hashem, Shrouk Medhat Youssef, Aliaa Muhammad Attyah, Malak Munir, Omar Shazly, Esraa Taha, Karim Wilson, Sawsan Adel, Asmaa Ali, Esraa Eid, Esraa Elhelow, Marwa Elmahdy, Bassant Elshatby, Amany Hossam el-din Zakaria, Ahmad Hossny, Eman Ibrahim, Ahmed M.Yonis, Maram Metwalli, Basant Yousry, Esraa Zid, Mina A Yacoub, Ahmed Abdelhakim, Nervana Abouelsoad, Mo'min Alkhatib, Ahmed Ashraf, Alaa Ashraf, Yasmin Elazab, Mahmoud Elfanty, Osama Elkabir, Mai Elsayed, Ahmed Elshimy, Hager Elsobky, John Eskander, Ahmed Gad, Ward Hamsho, Noura Khaled Abdelwahed, Menna Magdy, Dalia Moharam, Abeer Osama, Shereen Ramadan, Radwa Roum, Taqwa Sayed, Tarneem Shehada, Ahmed Mohy Zidan, Khalid Abbas, Amr Ali, Mohamed Attia, Mohamed Balata, Ayman El Nakeeb, Mohamed Ibrahim Elsayed Elewaily, Ahmed Elfallal, Hossam Elfeki, Ahmed Elkhadragy, Sameh Emile, Helmy Ezzat, Hasnaa Hosni, Islam Mansour, Waleed Omar, Gehad Othman, Kareem Sadek, Mostafa Shalaby, Noura Shehab-Eldeen, Rawda Anas khalifa, Helmy Badr, Mostafa Eldeep, Ahmed Eldeep, Amany Eldoseuky mohammed, Salwa Khallaf, Eman Magdy Hegazy, Rokia Mahmoud, Pola Mikhail, Mahmoud Morsi, Sara Mowafy, Dina Raafat, Amina Safy, Marwa Sera, Ahmed shible Sera, Mostafa Salim Mohamed AbdAllah, Muhammad Abdelkader, Abdulrahman Osama Abdou, Ahmedgaber Ahmed, Shireen Gaafar, Fatma Ibrahim negm, Mina Lapic, Ahmed Maher, Hagar Mahmoud, Ahmed Mostafa, Mohamed Samir, Fatma Samy, Nourhan Semeda, Hind I. Shalaby, Alaa El-taweel, Ahmed Galal Elnagar, Ahmed Gamal Hemidan, Mohamed Hussein, Ahmed.A. Kandil, Mf Moawad, Ayat Allah Nasser Hamamah, Mostafa Soliman, Mohamed Abdelkhalek, Noura Abdelmaksoud Tawakel, Ahmed Mohamed Abdelwahed, Alrawy Abdou, Khalid Atallah, Mohammed Yasser Elsherbeny, Eman Emara, Mohamed Hamdy, Omar Hamdy, Amira Haron, Salma Ismail, Islam Hany Metwally, Nihal Mohamed Hamed Elgaml, Ahmed Nassar, Basel Refky, Mirna Sadek, Mahmoud Saleh, Asmaa Yunes, Mai Zakaria, Mohammed Zuhdy, Notila Fayed, Mohammed Mustafa Hassan Mohammed, Sander Kütner, Priit Melnik, Indrek Seire, Toomas Ümarik, Eppu Ainoa, Verner Eerola, Hanna Koppatz, Laura Koskenvuo, Ville Sallinen, Sini Takala, Jevgeni Katunin, Arto Turunen, Niki Christou, Muriel Mathonnet, Vincent Lavoue, Krystel Nyangoh Timoh, Lucie Soulabaille, Romain Lesourd, Aude Merdrignac, Laurent Sulpice, Benoît André, Elodie Chantalat, Charlotte Vaysse, Bertrand Dousset, Sebastien Gaujoux, Gregory Martin, Octavian Clonda, Domantas Juodis, Klaus Kienle, Andras Mravik, Samuel Palmer, Gabor Szabadhegyi, Anita Eseenam Agbeko, Solomon Gyabaah, Frank Enoch Gyamfi, Nuhu Naabo, Atta Owusu senior, Joseph Yorke, Frank Owusu, Francis Abantanga, Theophilus Teddy Kojo Anyomih, Abdul-Jalilu Mohammed Muntaka, Emmanuel Owusu Abem, Mohammed Sheriff, Paul M. Wondoh, Dimitrios Balalis, Dimitrios Korkolis, Georgios Gkiokas, Eirini Pantiora, Theodosios Theodosopoulos, Argyrios Ioannidis, Konstantinos Konstantinidis, Sofia Konstantinidou, Nikolaos Machairas, Anna Paspala, Anastasia Prodromidou, Christos Chouliaras, Konstantinos Papadopoulos, Ioannis Baloyiannis, Ioannis Mamaloudis, George Tzovaras, Ioanna Akrida, Maria-Ioanna Argentou, Stylianos Germanos, Evangelos Iliopoulos, Ioannis Maroulis, George Skroubis, George Theofanis, Christos Chatzakis, Orestis Ioannidis, Lydia Loutzidou, Panagiotis Karathanasis, Nikolaos Michalopoulos, Charalampos Theodoropoulos, Dimitrios Theodorou, Tania Triantafyllou, Zoe Garoufalia, Natasha Hasemaki, Michalis Kontos, Gregory Kouraklis, Stylianos Kykalos, Theodore Liakakos, Eustratia Mpaili, Alexandros Papalampros, Dimitrios Schizas, Athanasios Syllaios, Ekaterini Christina Tampaki, Antonios Tsimpoukelis, Maria Ioanna Antonopoulou, Eirini Deskou, Dimitrios K. Manatakis, Dimitrios Papageorgiou, Menelaos Zoulamoglou, Christos Anthoulakis, Michalis Margaritis, Nikolaos Nikoloudis, Veronica Campo, André Ceballos, Mario-Andrés Flores, Waleska Giron, Donghyun Ko, Gabriel Martinez, Verónica Rivera Lara, Nataly Rueda, Andres Sanchez, Jorge Carlos Guillermo Tejeda Garrido, Alvaro Eduardo Alvarez Rivera, Elvis Benjamin Bamaca Ixcajoc, Lilian Elizabeth Barreda Zelaya, Patricia Chacòn-Herrera, Ligia Margarita Corea Ruiz, Guillermo Echeverria-Davila, Mario Garcia, Danilo García, Edgar Fernando Gutiérrez Mayen, Noriega José, Nery Mazariegos, Diego Méndez, Michael Paniagua Espinoza, David Bardos, Marton Benke, Kristof Illes, Balint András Kokas, Réka Szabó, Akhila Appukuttan, Anjitha Asok, Vijaykumar D.k, Kapil Malik, Praveen Ravishankaran, Ritesh Tapkire, Guru Moorthy, Joyner Abraham, Ramesh Muthuvel, John Alapatt, Abhay Kattepur, Nizamudheen Pareekutty, Mebanshanbor Garod, Caleb Harris, Cliff Wanniang, Ashish Gupta, Deepak Nehra, Sanjeev Parshad, Rajgopal Acharya, Rajendra Badwe, Manish Bhandare, Urvashi Jain, Karishma Kirti, Nita Nair, Shailesh Shrikhande, Purvi Thakkar, Premkumar Anandan, Archana C S, Arun Holenarasipur Narasannaiah, Tejaswi Jagarlamudi, Rashmi M R, Mallikarjuna Manangi, Abhishek Raghavendra, K. Seshagiri Rao, Vinay S, Vinay Sajjan, Aneesh Shenoy, Santhosh Shivashankar Chikkanayakanahalli, Kavya Tharanath, Sushmita V, Peter Adidharma, Raksheeth Agarwal, Phebe Anggita Gultom, Ghafur Rasyid Arifin, Matthew Billy, Zatira Elfizri, Alessa Fahira, Devi Felicia, Triana Hardianti Gunardi, Nadya Johanna, Nadia Rahmadiani Nugrahadi, Sonar Soni Panigoro, Siti Rahmayanti, Retta Catherina Sihotang, Santi Yuanita Brata, Hadi Winoto, Nastaran Barati, Manoochehr Karami, Hamidreza Khorshidi, Homa Naderifar, Mazin A. Abdulla, Maggie Coleman, Ronan J Doherty, Rob Hannon, Brenda Murphy, Aine Stakelum, Des Winter, Lylas Aljohmani, Richard Farnan, Yeshey Seldon, Tanna Tan, Shriya Varghese, Mohammad Alherz, Muaaz Ather, Mohammad Bajilan, Vivien Graziadei, Isobel Pilkington, Omar Quidwai, Paul Ridgway, Haaris Shiwani, Abd al-Rahman Tahir, Eimear Blunnie, Daniel Burke, Niall Kennedy, Kate Macdonagh, Maeve O'Neill, Siobhan Rooney, Giuseppe Falco, Guglielmo Ferrari, Simone Mele, Gabriela Elisa Nita, Lara Ugoletti, Maurizio Zizzo, Gianmaria Confalonieri, Giovanni Pesenti, Fulvio Tagliabue, Gianluca Baronio, Deborah Ongaro, Giacomo Pata, Bruno Compagnoni, Renato Salvadori, Lucio Taglietti, Nicola D'Alessandro, Pierpaolo Di Lascio, Giovanni Pascale, Luca Bortolasi, Tommaso Campagnaro, Massimo Carlini, Giorgio Lisi, Davide Lombardi, Corrado Pedrazzani, Domenico Spoletini, Giulia Turri, Paola Violi, Donato Francesco Altomare, Fabrizio Aquilino, Nicola Musa, Vincenzo Papagni, Arcangelo Picciariello, Leonardo Vincenti, Dario Andreotti, Savino Occhionorelli, Matteo Tondo, Stefano Maria Massimiliano. Basso, Riccardo Cirelli, Marco Enrico Mario Maino, Guglielmo Niccolò Piozzi, Emanuele Picone, Rosa Scaramuzzo, Giovanni Sinibaldi, Alfonso Amendola, Lorenzo Anastasio, Luigi Bucci, Emanuele Caruso, Antonio Castaldi, Sara Di Maso, Vincenza Paola Dinuzzi, Giovanni Esposito, Maria Gaudiello, Mariano Cesare Giglio, Paola Antonella Greco, Gaetano Luglio, Andrea Manfreda, Ester Marra, Federica Mastella, Gianluca Pagano, Roberto Peltrini, Vincenzo Pepe, Michele Sacco, Viviana Sollazzo, Giovanni Spiezio, Ettore Cianchetti, Nunzia Menduni, Michele Maria Carvello, Francesca Di Candido, Antonino Spinelli, Fabio Corsi, Luca Sorrentino, Fabio Marino, Emanuele Luigi Giuseppe Asti, Luigi Bonavina, Emanuele Rausa, Martina Asta, Andrea Belli, Francesco Bianco, Carmela Cervone, Paolo Delrio, Armando Falato, Andrea Fares Bucci, Rita Guarino, Ugo Pace, Daniela Rega, Emilia De Luca, Gaetano Gallo, Giuseppe Sammarco, Giuseppe Sena, Giuseppina Vescio, Letizia Santandrea, Giampaolo Ugolini, Davide Zattoni, Nicola Chetta, Gaetano Logrieco, Serafino Vanella, Gianluca Garulli, Nicola Zanini, Andrea Bondurri, Francesco Cammarata, Francesco Colombo, Diego Foschi, Giulia Maria Beatrice Lamperti, Anna Maffioli, Gianluca Matteo Sampietro, Al'ona Yakushkina, Gloria Zaffaroni, Enrico Cicuttin, Maria Grazia Sibilla, Harmony Impellizzeri, Marco Inama, Gianluigi Moretto, Sylvie Mochet, Elisa Ponte, Antonella Usai, Stefano Mancini, Andrea Sagnotta, Luigi Solinas, Elisa Bolzonaro, Nicolò Tamini, Gianluca Curletti, Raffaele Galleano, Michele Malerba, Sofia Campanella, Gianfranco Cocorullo, Francesco Colli, Paolino De Marco, Nicolò Falco, Tommaso Fontana, Leonel jospin Kamdem Mambou, Antonella La Brocca, Leo Licari, Brenda Randisi, Giovanna Rizzo, Giulia Rotolo, Giuseppe Salamone, Roberta Tutino, Paolina Venturelli, Stefano Malabarba, Alessandro Sgrò, Ivan Vella, Bruno Cirillo, Daniele Crocetti, Giorgio De Toma, Pierfrancesco Lapolla, Andrea Mingoli, Paolo Sapienza, Angela Belvedere, Stefania Bianchini, Margherita Binetti, Arianna Birindelli, Valeria Tonini, Mauro Podda, Fabio Pulighe, Michele De Rosa, Lorenzo Bono, Felice Borghi, Paolo Geretto, Maria Carmela Giuffrida, Corrado Lauro, Alessandra Marano, Luca Pellegrino, Paola Salusso, Diego Sasia, Michela Campanelli, Alberto Realis Luc, Mario Trompetto, Roberto Cardia, Nicola Cillara, Antonio Nicola Giordano, Antonio Costanzo, Mario Alessandro Giovilli, Luca Turati, Silvestro Canonico, Guido Sciaudone, Francesco Selvaggi, Lucio Selvaggi, Nader Albsoul, Ahmad AlBsoul, Ala'a Aldeen Alkhatib, Osama Alsallaq, Justin Z. Amarin, Rami Ayoub, Isam Bsisu, M S El Muhtaseb, Mohammad Jabaiti, Jamal Melhem, Yasmeen Z. Qwaider, Mohammad Hasan Salameh, Ahmad Suleihat, Haya H. Suradi, Mohammad Alammarin, Almoutuz Aljaafreh, Mohammad Bani hani, Zeina Bani hani, Farah Bani Hani, Toqa Fahmawee, Shadi Hamouri, Cyrine Katanani, Ra'fat Tawalbeh, Tamara Tawalbeh, Hassan Zawahrah, Mohamad K. Abou Chaar, Lana Abusalem, Mahmoud Al-Masri, Hani Al-Najjar, Lutfi Barghuthi, Zahra Ahmed, Adnan Maulana, Omar Ngotho, Charbel Kamau, Aruyaru Stanley Mwenda, Fridah Bosire, Elizabeth Mwachiro, Robert Parker, Ian Simel, Kimutai Sylvester, Abdulmunem Ahmed Mustafa Althini, Sofian Elbarouni, Aya Elseed Elbeshina, Ahmed Gwea, Ans Malek, Wedad Albashir Masoud Farag, Abdulwahab Abdalei, Abu Baker Abdel Malik, Areej Abo-khammash, Ma'aly Abuhlaiga, Nour Adnan, Marwa Albaggar, Asma Alfitory, Asma Aljanfi, Fakhruddin Almuzghi, Zohoor Altumei, Fatima Alzabti, Hana Ashoushan, Mohamed Assalhi, Joma Azzubia, Sondos Bnhameida, Malik Delhen, Houssein Elshafei, Hana Elteir, Fatima Esbaga, Abdel Aziz Gobbi, Fatma Hamouda, Hamdan Hilan, Rania Ismail, Fieruz Jebran, Muataz Kasbour, Galia Maderi, Saja Mohammad, Burooj Mohammed, Habib Murtadi, Hamassat Mustafa, Mohamed Rajab, Sarah Trenba, Mariam Wafaa, Eman Al Sagheir, Alabas Almigheerbi, Ahmed Alzahaf, Sumayyah Ghayth Bahroun, Najah Ben Dallah, Mahmoud Elshaibani, Haitem Eswaye, Maha Karar, Samah Omar, Eman Younes, Maha Younes, Dafer Zreeg, Saleh Abujamra, Firas Ashour, Mala Elgammudi, Wesal Omar F. Aljadidi, Enas Saddouh, Randa Sharif, Aya Alabuzidi, AbdulMawlay Alwerfally, Sarra Aribi, Fatma Bibas, Taha Elfaituri, Yasmine Elhajjaji, Ala Khaled, Wegdan Khalil, Tesneem Layas, Enas Soula, Ahmed Tarek, Muad fathi khalleefah Abu hallalah, Hazem Abdelkarem Ahmed, Tagwa Alsharef, Abdulsalam Ali Ben Saoud, Tasnim El Gharmoul, Ahmed Elhadi, Safa Elrais, Abdulhalim Shebani, Heba Zarti, Asaid Zeiton, Marijus Ambrazevicius, Nerijus Kaselis, Migle Stakyte, Oleg Aliosin, Agne Cizauskaite, Sarunas Dailidenas, Vitalijus Eismontas, Migle Kybransiene, Vitalija Nutautiene, Narimantas Samalavicius, Dainius Simcikas, Algirdas Slepavicius, Albinas Tamosiunas, Nerijus Ubartas, Paulius Zeromskas, Saulius Bradulskis, Edvinas Dainius, Juozas Juocas, Egle Kubiliute, Juozas Kutkevicius, Aurimas Opolskis, Audrius Parseliunas, Andrejus Subocius, Egle Virbickaite, Diana Zuikyte, Algirdas Bogusevicius, Kristina Buzaite, Daiva Cepuliene, Ieva Cesleviciene, Vaidotas Cesna, Jolanta Gribauskaite, Povilas Ignatavicius, Mantas Jokubauskas, Monika Liugailaite, Ernest Margelis, Ruta Mazelyte, Lina Pankratjevaite, Matas Pažusis, Agne Rackeviciute, Justina Saladyte, Monika Škimelyte, Vygintas Šlenfuktas, Monika Sudeikyte, Algimantas Tamelis, Tomas Vanagas, Žygimantas Žumbakys, Aivaras Atkociunas, Audrius Dulskas, Justas Kuliavas, Justas Birutis, Sigitas Paškevicius, Mindaugas Šatkauskas, Donatas Danys, Matas Jakubauskas, Lina Jakubauskiene, Marius Kryzauskas, Vytautas Lipnickas, Gabija Makunaite, Fanjandrainy Rasoaherinomenjanahary, Herizo Rasolofonarivo, Luc Hervé Samison, Bitiel Banda, Vanessa Msosa, Ahmad Imran Ahmad Izzuddin, Andre Das, Ying Yee Gan, Tan Shong Sheng, Jia yng Siaw, Mohd Fadliyazid Ab Rahim, Dyg Zahratul Hamrak Abang Jamari, Nurfariza Che Husin, Muhd Yusairi Kamarulzaman, Yi Ping Lim, Nil Amri Mohamed Kamil, Mohd Razeen Mohd Hassan, Saidah Mohd Sahid, Johari Mustafa, Elaine Hui Been Ng, Wan Khamizar Wan Khazim, Ng Chang Ern, P.g. Lingeshan, Syariz Ezuan Sulaiman, Sue Ean Ang, Muhammad Navid Bin Mohamad Sithik, Yih Jeng Cheong, Mahadevan Deva Tata, Law Jia Xian, Aravinthan Kadravello, I-Ern Koh, Li-Yen Ng, Yuki Julius Ng We Yong, Kandasami Palayan, Chi Xuan Sam, Phuah Siow Jin, Jeremy Tan Ern Hwei, Yita Tang, Alvin Zubin Ter, Michael Pak-Kai Wong, Andee Dzulkarnaen Zakaria, Zaidi Zakaria, Fitjerald Henry, Thyivya Kalaiselvan, Muhammad Fairuz Shah Abd Karim, Mohamed Rezal Abdul Aziz, Nora Abdul Aziz, Tak Loon Khong, Peng Choong Lau, Hiong Chin Lim, April Camilla Roslani, Jonathan Chen Ken Seak, Sui-Weng Wong, Lai Fen Wong, Leow Yeen Chin, Mercy Chinemerem Anyanwu, Zachary Busuttil, Thomas Calleja, Kurt Lee Chircop, Ruth Cutajar, Andrew Michael Dimech, Joseph Galea, Kiara Gascon Perai, Ruth Gatt, Lisa Kelman, Elizabeth Micallef, Favour Nwolu, Kim Sammut, Joanna Thompson, Sean Warwicker, Matthew Zammit, Fernando Cordera, Efraín Cruz González, Jorge Sánchez-García, Francisco José Barbosa Camacho, Francisco Javier Barrera López, Carlos Jose Zuloaga Fernandez del Valle, Eric Acosta, Iván Romarico González Espinoza, Perla Moreno, Ana Olivia Cortes-Flores, Clotilde Fuentes Orozco, Alejandro Gonzalez Ojeda, Samantha Corro Díaz González, Laura Martinez, Bonifacio Mosqueda Amador, Armando Novoa, Dennet Arturo Olazo Espejo, Alejandro Jimenez, Federico Lopez Rosales, Elva Gabriela Vanoye, Luis Alberto Garcia Gonzalez, Roberto Carlos Miranda-Ackerman, Manuel Solano-Genesta, Alethia Alvarez-Cano, Hector Hugo Romero-Garza, Heriberto Medina-Franco, Lorelí Mejía-Fernández, Noel Salgado-Nesme, Omar Vergara-Fernandez, Guadalupe Montserrat Gutiérrez-Mota, Francisco Xavier Hernandez Vera, Anabella Llantada Lopez, Gilberto Morgan Villela, Felipe de Jesus Ramirez Padilla, Walezka Tapia Marin, Mónica Martínez Maldonado, Ramses Sánchez Suárez, José Manuel Troche, Chaymae Benyaiche, Oumaima Outani, Souadka Amine, Amine Benkabbou, Anass Mohammed Majbar, Raouf Mohsine, Ali Rafik, Thida Oung, Moe Moe Tin, Philipp Plarre, Anna Alberga, Nina Sluiter, Jurriaan Tuynman, Robin Blok, Didem Cömert, Roel Hompes, Marianne Kalff, Merel Elisabeth Stellingwerf, Pieter Tanis, Mark van Berge Henegouwen, Elise Maria van Praag, Daan Wisselink, Michael Gerhards, Josephine Lopes Cardozo, Emma Westerduin, Joske de Jonge, Aaw van Geloven, Kaz van Schilt, Frank den Boer, Simone Stoots, Stijn Vlek, Jamie Adams, Ibrahim S. Al-Busaidi, Gabrielle Budd, Seung il Choi, Michael Jen Jie Chu, Anurag Ganugapati, Lucy McKinstry, Rebecca Pascoe, Simon Richards, Kenrick Rosser, Annie Stevenson, Rebecca White, Shebani Farik, Jin Kwun, Ahmed Murad, Sarah Cowan, Timothy Hall, Michael Hayton, Laminou Malam Sani, Souleymane Oumarou Garba, Ibrahim Amadou Magagi, Oumarou Habou, Halima Aliyu, Muhammad Daniyan, Tunde T. Sholadoye, Lawal Abdullahi, Lofty-John Anyanwu, Aminu Mohammad Mohammad, Abubakar Bala Muhammad, Abdurrahman Abba Sheshe, Ibrahim Suleiman, Alaba Adesina, Ajibola Awolowo, Clement Onuoha, Omotayo Salami, Ogechukwu Taiwo, Agboola Taiwo, Stephen Kache, Jerry Godfrey Makama, Danjuma Sale, Olajide Abiola, Akinlabi Ajao, Anthony Ajiboye, Amarachukwu Etonyeaku, Julius Olaogun, Ademola Adebanjo, Opeoluwa Adesanya, Michael Olatunji Afolayan, Olanrewaju Balogun, Ayomide Makanjuola, Samuel Nwokocha, Rufus Wale Ojewola, Thomas Olagboyega Olajide, Adewale Aderounmu, Abdul-Rashid Adesunkanmi, Augustine Agbakwuru, Adeleke Akeem Aderogba, Olusegun Isaac Alatise, Olukayode Arowolo, Oladejo Lawal, Tajudeen Mohammed, Chinedu Ndegbu, Olalekan Olasehinde, Funmilola Wuraola, Akinbolaji Akinkuolie, Arinzechukwu Mosanya, Omobolaji Ayandipo, Peter Elemile, Taiwo Akeem Lawal, Samuel Ali SANI, Stephen Garba, Rebecca Hauwa SANI, Samson Olori, Henry Onyebuashi, Ifeanyi Umoke, Adedire Adenuga, Ademola Adeyeye, Olufemi Habeeb, Bashir Lawal, Abdulrasheed Nasir, Eirik Kjus Aahlin, Didrik Kjønås, Elisabeth Myrseth, Jibran Abbasy, Abdul Alvi, Omair Saleem, Asma Afzal, Anam Nazir, Muhammad Farooq, Ayesha Liaqat, Syed Asghar Naqi, Ali Raza, Muzna Sarfraz, Muhammad Sarwar, Muntaha Banglani, Ambreen Munir, Rahmat Sehrish, Bushra Ayub, Raza Sayyed, Amna Altaf, Saima Ayub, Komal Saeed, Bilal Syed, Sana Amir Akbar, Abdul Wahid Anwer, Ruqayya Naheed Khan, Amina Iqbal Khan, Shahid Khattak, Sameen Mohtasham, Muhammad Asad Parvaiz, Aamir Ali Syed, Abdul Basit Ansari, Noman Shahzad, Tanwir Khaliq, Isbah Rashid, Shahzad Hussain Waqar, Hasan Abu Al-saleem, Amjad Abu Alqumboz, Mohammad Alqadi, Adham Amro, Rawan Assa, Eman Awesat, Rawan Ayyad, Mohammed Hammad, Ayat Haymony, Bassel Hijazi, Bara Hmeidat, Rowaa Lahaseh, Aseel Qawasmi, Alaa Rajabi, Mohammed Shehada, Sundus Shkokani, Yasmine Yaghi, Nadine Yaghi, Mohammad AlZohour, Mohammad Farid, Yousef Mahmoud Habes, Wesam Juba, Yanal Nubani, Abdelrahman Rabee, Mohammad Sa'deh, Saeed Abed, Iyad Al basos, Mohammad Alswerki, Dina Ashour, Israa Awad, Samar Diab, Alaa El Jamassi, Sahar El-Kahlout, Somaya Elhout, Ahmed N K Hajjaj, Doaa Hasanain, Baraa Nabil hajjaj, Mohammed Obaid, Eman Saikaly, Ahmed Salhi, Hiba Al-Tammam, Murad Almasri, Muath Baniowda, Doha Beshtawi, Ali Horoub, Rami Misk, Bayan Mohammad, Rami Qasrawi, Tasnim Sholi, Samar Abu-Nimeh, Abrar Abu-srour, Sadi A. Abukhalaf, Samer Adawi, Barah Alsalameh, Kholoud Ayesh, Muawiyah Elqadi, Ahmad Hammouri, Fatima Karim Mustafa, Natalie Marzouqa, Shatha Melhem, Dima Miqdad, Balqees Mohamad, Mhammed Rawhi, Ayman B. Abu Ahammala, Ahmed Abu Ataya, Israa Abu Jayyab, Samar Al-Shwaikh, Othman Alagha, Mohammed Alasttal, Haneen Awadallah, Mahmood Elblbessy, Jehad Fares, Akram Jarbou, Ibtisam Mahfouz, Moath A. Albahnasawi, Asmaa' Abo mahadi, Hasan Abuelhatal, Ayham Abuelqomboz, Abdelrahman Almoqayyad, Abdallah Alwali, Reem Balaawi, Mahmoud Hamouda, Mohammed Humeid, Abdullah Jedyan, Tasneem Mahmoud Abu hamam, Ghadeer Matar, Ali Salem, Tahani Samra, Nureddin Shaheen, Karam Shihada, Ayoob A.Nemer, Mahmoud Abu Al Amrain, Abdulwhhab Abu Alamrain, Najlaa Abu Jamie, Mohammed R. Abu-Rous, Nada Alfarra, Mohammed AlTaweel, Noor Alwhaidi, Ramadan Hamed, Bader Saqqa, Ahmad Shaheen, Dana Aljaber, Loay Aljaberi, Malak Alwaheidi, Assef Jawaada, Hani Khaldi, Rami Qahoush, Jalil Qari, Rana Saadeh, Ahlam Salim, Aseel Yacoub, Abbas Abbas, Rana Abu shua`ib, Baraa Abu Zainah, Mahmoud AbuSirrees, Basheer Babaa, Ola Barhoush, Asef Belal qadomi, Laith Daraghmeh, Reema Haji, Alaa Khatatbeh, Lana Khatib, Salsabeel Qarariah, Yara Quzmar, Khalil Safadi, Roqaya Salameh, Mohammad Hassan, Shifaa Herzallah, Loai Massad, Ahmed Nazzal, Ranin Nazzal, Dennis Escobar, Gustavo Miguel Machain V, Agustin Rodriguez Gonzalez, Jorge Emerson Chachaima Mar, Nathaly Olga Chinchihualpa Paredes, Vicente Cuba, Walter Lopez, Maria Milagros Niquen Jimenez, Nestor Alberto Sanchez Bartra, Olenka Sapallanay Ojeda, Diego Sequeiros, Andrea Toscano Pacheco, María Vergara, Sol Abarca, Rodrigo Alcorta, Giuliano Borda-Luque, Ivan Edward Eusebio Zegarra, Claudia Luján López, Mirella Marrufo, Cinthya Mogrovejo, Andrea Nomura, Yamile Rodríguez Angeles, Maitza Rosario Vidal Meza, Gabriela Zavala, José Neiser Castillo Arrascue, Jomara Caroline Hidrogo Cabrera, José Julio Mariano Larrea vera, Miguel Osorio, Edgar Alcides Ylatoma Díaz, Mark Anthony Fontanilla, Joseph Roy Fuentes, Anna Leah Salazar, Genieve Dominguez, Marc Paul Lopez, Shiela Macalindong, Mark Augustine Onglao, Arjel Ramirez, Marie Dione Sacdalan, Mayou Martin Tampo, Gemma Leonora Uy, Jeremiah Mangahas, Kenneth Yabut, Joannes Paul Cañete, Bernalynn Eris Cansana, Ernes John Castro, Maria Kaiserin Lipana, Manuel Francisco Roxas, Vlu Jean Zara, Maciej Chrol, Paula Franczak, Michal Orlowski, Piotr Budzynski, Andrzej Budzynski, Pawel Bury, Agata Czerwinska, Jadwiga Dworak, Jacek Dziedzic, Michal Kisielewski, Jan Kulawik, Anna Lasek, Piotr Malczak, Marcin Migaczewski, Michal Pedziwiatr, Magdalena Pisarska, Dorota Radkowiak, Mateusz Rubinkiewicz, Anna Rzepa, Tomasz Skoczylas, Maciej Stanek, Katarzyna Truszkiewicz, Mateusz Wierdak, Marek Winiarski, Piotr Zarzycki, Anna Zub-Pokrowiecka, Piotr Kowalewski, Rafal Roszkowski, Maciej Waledziak, Miguel Tomé, Sara Patrocinio, Ines Guerreiro, Filipe Almeida, Xavier de Sousa, Nuno Monteiro, Maria Teresa Costa Santos, Daniela de Oliveira, Marta Lopes Serra, Daniela Morgado, Christian Neves, Ana Carolina Oliveira, Alice Pimentel, Sofia Silva, Márcia Carvalho, Lúcia Carvalho, Joana Magalhães, Leonor Matos, Tânia Monteiro, Carlota Ramos, Vanessa Santos, José Barbosa, Jose Costa-Maia, Vítor Devezas, Ana Fareleira, Cristina Fernandes, Diana Gonçalves, Henrique Mora, Marina Morais, Fabiana Silva de Sousa, Sara Catarino Santos, Ana Logrado, André Tojal, Edgar Amorim, Miguel F. Cunha, Ana Fazenda, João Pedro Melo Neves, Inês Isabel Sampaio da Nóvoa Gomes Miguel, Diogo Veiga, José Azevedo, Hugo Cardoso Louro, Mariana Leite, Maria Bairos Menezes, Bárbara Gama, Diana Brito, Marta Cristina Cruz Martins, André Graça e Magalhães, Ana Catarina Longras, Rita Lourenço, Diana Matos, Luis Castro, Filipa Policarpo, Joana Romano, Cristina Monteiro, Diogo Pinto, Marina Duarte, Sónia Fortuna Martins, Mariline Oliveira, Diogo Galvão, Lisandra Martins, Anaisa Silva, Viorel Taranu, Bárbara Vieira, Jessica Neves, Simone Oliveira, Hugo Ribeiro, Margarida Cinza, Rosa Felix, Arnaldo Machado, Joana Oliveira, Joana Patrício, Rita Pedroso de Lima, Mário Pereira, Miguel Rocha Melo, Cristina Velez, Alberto Abreu da Silva, Mariana Claro, Daniel Costa Santos, Andreia Ferreira, Hugo Capote, Daniela Rosado, Filipa Taré, Oriana Nogueira, Miguel Ângelo, José Miguel Baiao, Andreia Guimarães, João Marques, Miguel Nico Albano, Marta Silva, Ana Valente da Costa, Teresa Vieira Caroço, Sara Almeida Braga, Ines Capunge, Marta Fragoso, João Guimarães, Bruno Pinto, João Ribeiro, Miguel Angel, Guilherme Fialho, Monica Guerrero, Filipa Campos Costa, Diogo Cardoso, Vasco Cardoso, Magda Alves, Inês Estalagem, Tiago Louro, Cláudia Marques, Rita Martelo, Miguel Morgado, Rita Canotilho, Ana Margarida Correia, Pedro Martins, Mariana Peyroteo, João Gomes, Rita Monteiro, Manuela Romano, Daniela Macedo Alves, Rita Peixoto, Catarina Quintela, Maria João Jervis, Débora Melo, André Pacheco, Valter Paixão, Vera Pedro, Joana Pimenta, João Pimenta de Castro, Ana Rocha, Mircea Beuran, Cezar Ciubotaru, Bogdan Diaconescu, Sorin Hostiuc, Ionut Negoi, Bogdan Stoica, NA NA, Evgeny Anokhin, Georgy Kuznetsov, Giorgi Oganezov, Fedor Paramzin, Ekaterina Romanova, Valeryan Rutkovskii, Vasilii Rutkovskii, Mikhail Shushval, Mikhail Zabiyaka, Khasan Dzhumabaev, Valerii Ivanov, Zaman Mamedli, Sergey Achkasov, Artem Balkarov, Elnur Nabiev, Marat Nagudov, Evgeny Rybakov, Karina Saifutdinova, Oleg Sushkov, Lule Joseph, Isaac Ndayishimiye, Ntirenganya Faustin, Alphonse Zeta Mutabazi, Jean Paul Mvukiyehe, Vizir J.P Nsengimana, Carine Uwakunda, Mohammad Monir Abbas, Nouf Akeel, Murad Aljiffry, Kholoud Awaji, Ali Farsi, Ghader Jamjoum, Ahmad Khoja, Ashraf Maghrabi, Nadim Malibary, Mohammed Nassif, Abdulaziz Saleem, Abdullah Sultan, Wail Tashkandi, Hanaa Tashkandi, Nora Trabulsi, Mouhamadou Bachir Ba, Adja Coumba Diallo, Abdourahmane Ndong, Vladica Cuk, Uroš Jankovic, Sharon Zhiling Koh, Frederick Koh, Kuok Chung Lee, Kai Yin Lee, Sean Lee, Wei Qi Leong, Su Ann Lui, Prajwala Prakash, Jan Grosek, Gregor Norcic, Ales Tomazic, Nicolas Fitchat, Robert Jaich, Devorah Wineberg, Modise Zacharia Koto, Daniella Baiocchi, Damian Clarke, Christina Johanna Steenkamp, Sharon Bannister, Adam Boutall, Galya Chinnery, Anna Coccia, Angela Dell, Parveen Karjiker, Christo Kloppers, Nicholas Loxton, Tumi Mabogoane, Francois Malherbe, Eugenio Panieri, Shreya Rayamajhi, Tirsa van Wyngaard, Claire Warden, T E Madiba, Nivashen Pillay, Savannah Brooks, Charlise Kruger, Lisa Hannah Van Der Merwe, Ferhana Gool, Maahir Kariem, Heather Bougard, Nazmie Kariem, Fazlin Noor, Reantha Pillay, Leandi Steynfaardt, Lucía González González, José Miguel Marín Santos, Paula Martín-Borregón, Javier Martínez Caballero, Cristina Nevado García, Pastora Rodriguez Fraga, Gonzalo De Castro Parga, Maria Pilar Fernández Veiga, Lucía Garrido López, Hugo Infante Pino, Irene Lages Cal, Marta López Otero, Manuel Nogueira Sixto, Marta Paniagua García Señorans, Laura Rodríguez Fernández, Alejandro Ruano Poblador, Erika Rufo Crespo, Raquel Sanchez-Santos, Vincenzo Vigorita, Ester Alonso Batanero, Dorisme Asnel, Isabel Cifrian Canales, Elisa Contreras Saiz, Irene De Santiago Alvarez, Tamara Díaz Vico, Sebastian Fernandez Arias, Daniel Fernández Martínez, Carmen García Bernardo, Luis Joaquín García Flórez, Carmen Garcia Gutierrez, Manuel García Munar, Carlos Alberto Márquez Zorrilla Molina, Marta Merayo, José Luis Michi Campos, Maria Moreno Gijon, Jorge L. Otero-Diez, Jose Luis Rodicio Miravalles, Lorena Solar-Garcia, Aida Suárez Sánchez, Nuria Truan, Cristina Alejandre Villalobos, Yurena Caballero Díaz, Marta Jimenez, Dacil Montesdeoca, Antonio Navarro-Sánchez, Victor Vega, Juan Beltrán de Heredia, Zahira Gómez, Carlos Jezieniecki, Ana Patricia Legido Morán, Mario Montes-Manrique, Mario Rodriguez-Lopez, María Ruiz Soriano, Jeancarlos Trujillo Díaz, Andrea Vazquez Fernandez, Nuria Argudo, Miguel Pera, Laia Torrent Jansà, Melody García Domínguez, Ignacio Goded, Marta Roldón Golet, Issa Talal El-Abur, Alejandra Utrilla Fornals, Vanesa Zambrana Campos, Maria Del Mar Aguilar Martinez, Marina Bosch, Luis García-Catalá, Luis Sánchez-Guillén, Eva Artigau, Nuria Gomez Romeu, David Julià Bergkvist, Beatriz Espina Perez, Olga Morató, Carles Olona, Beatriz Diéguez, Alexander Forero-Torres, Manuel Losada, Segundo Gomez-Abril, Paula Gonzálvez, Rosario Martinez, Sergio Navarro Martínez, Carmen Payá-Llorente, Álvaro Pérez Rubio, Sandra Santarrufina Martinez, Juan Carlos Sebastián Tomás, Ramon Trullenque Juan, Alberto Gegúndez Simón, Paloma Maté, Maria Isabel Prieto-Nieto, Ines Rubio-Perez, Aitor Urbieta, Marina Vicario Bravo, David Abelló, Matteo Frasson, Alvaro Garcia-Granero, Alfredo Abad Gurumeta, Ane Abad-Motos, Elena Lucena-de Pablo, Beatriz Nozal, Javier Ripollés-Melchor, Rut Salvachúa, Esther Ferrero, Luis Garcia-Sancho Tellez, Antonio L. Picardo, Jose Alberto Rojo López, Laura Patricia Zorrilla Matilla, Carmen Cagigas Fernandez, Sonia Castanedo Bezanilla, José Estevez Tesouro, Maria Jose Fernandez-Diaz, Juan García Cardo, Marcos Gomez Ruiz, Erik Gonzalez-Tolaretxipi, Jaime Jimeno Fraile, Cristobal Poch, Montserrat Rodriguez-Aguirre, Noemí Troche Pesqueira, Maria Soledad Trugeda-Carrera, Javier de la Torre, Ruth Blanco-Colino, Eloy Espin-Basany, Martin Espinosa-Bravo, Clara Morales Comas, Eduardo Reyes Afonso, Joaquín Rivero Déniz, Christian Siso Raber, Mireia Verdaguer Tremolosa, Pramodh Chandrasinghe, Sumudu Kumarage, Nimeshi Wijekoon Arachchilage, Ahmed Abdalla Ahmed Elkamel, Mohammed A. Adam, Nina Blomme, Anders Thorell, Fredrik Wogensen, Andreas Älgå, Dhirar Ansarei, Fuat Celebioglu, Göran Heinius, Linda Nigard, Emil Pieniowski, Sandra Ahlqvist, Ida Björklund, Andreas Frånberg, Martina Håkansson, Karin Adamo, Oskar Franklin, Malin Sund, Rebecca Wiberg, Yvette Andersson, Abbas Chabok, Maziar Nikberg, Alexander Kugelberg, Claudia Canonica, Dimitrios Christoforidis, Fabrizio Fasolini, Paolo Gaffuri, Mauro Giuliani, Francesco Meani, Sotirios Georgios Popeskou, Silvia Pozza, Wiebke Wandschneider, Lorenz Peterer, Lukas Werner Widmer, Bernd Zimmermann, Panagiotis Bakoleas, Iris Chanousi, Lydia Charalampidou, Lukasz Filip Grochola, Franziska Heid, Sotirios Ntaoulas, Michail Outos, Georgios Peros, Hanna Podolska-Skoczek, Katharina Beate Reinisch, Christian Zielasek, Nicolas Demartines, Jérôme Gilgien, Amaniel Kefleyesus, Pénélope St-Amour, Arnaud Toussaint, Maryam Alhimyar, Bayan Alsaid, Amr Alyafi, Ahmad Alkhaledi, Basel Kouz, Ahmad Omarain, Yusra Al-Sabbagh, Haya Alkhatib, Samer Sara, Ahmad Alhaj, Aghyad Danial, Lama Kadoura, Sarah Maa Albared, Yamen Monawar, Louei Nahas, Barook Abd, Ahmad Saad, Habib Wakkaf, Hatem Bouzaiene, Montassar Ghalleb, Elif Akaydin, Ata Cem Akbaba, Onur Atakul, Ege Baltaci, Sevval Besli, Gökçen Burgu, Ulukan Cenal, Cansu de Muijnck, Hasan Can Demirkaya, Alper Dogruoz, Zeynep Ipek Gezer, Yasemin Gündogdu, Merve Kara, Hasan Kürsad Korkmaz, Gökalp Kagan Kurtoglu, Volkan Ozben, Berk Baris Ozmen, Ahmet Murat Pektas, Eda Kübra Sel, Nilüfer Yenidünya, Fuat Baris Bengur, Berke Mustafa Oral, Tahir Koray Yozgatli, Seymur Abdullayev, Mehmet Emin Gunes, Nuri Alper Sahbaz, Tuba Banaz, Kübra Kargici, Omer Faruk Kuyumcu, Erkan Yanikoglu, Merve Yesilsancak, Duygu Yilmaz, Melik Kagan Aktas, Ahmet Rencuzogullari, Arda Isik, Sezai Leventoglu, Ali Yalçinkaya, Osman Yüksel, Mustafa U Kalayci, Yasin Kara, Inanc Samil Sarici, Alp Akin, Gökçe nur Alemdag, Ekin Arslan, Bahadir Emre Baki, Muhammed Selim Bodur, Adnan Calik, Bahar Candas Altinbas, Irem Cihanyurdu, Oguz Erkul, Burak Gül, Ali Guner, Beyza Köse, Anil Semiz, Sule Sevim, Serkan Tayar, Kadir Tomas, Ozan yavuz Tüfek, Serdar Türkyilmaz, Mehmet Ulusahin, Arif Usta, Reyyan Yildirim, Sertaç Ata Güler, Ozan Can Tatar, Ecenur Varol, Busenur Kirimtay, Muhammed Uysal, Alp Yildiz, Emin Kose, Ahmet Burak Ciftci, Elif Çolak, Huseyin Eraslan, Gultekin Ozan Kucuk, Kürsat Yemez, Herman Lule, Mumbere Bienfait, Emmanuel Bua, Noella Okalany, Maksym Basarab, Oleksii Bielosludtsev, Kateryna Kolhanova, Kateryna Perepelytsia, Kateryna Romanukha, Dmytro Savenkov, Stanislav Siryi, Maksym Tereshchenko, Nezamai Viacheslav, Anton Volovetskyi, Andrey Kebkalo, Yegor Tryliskyy, Volodimir Tyselskiy, Eilidh Bruce, Bing Lun Chow, Emma Iddles, Sarah McGuckin, Nicola Newall, George Ramsay, Parivrudh Sharma, Caitlin Stewart, Jeremy Wong, Abdul Badran, Michael Bath, Fanny Belais, Eman Butt, Kaustuv Joshi, Milan Kapur, Mike Shaw, Adam Townson, Christopher Yee Khang Williams, Timothy Gray, Robert Greig, Mansoor Husain, Elspeth Murray, Ahmed Mustafa, Ashar Asif, Arya Gokul, Max Shah, Mabel Temisanren Akitikori, Alexandros Charalabopoulos, Sophie Davidson, Sinead McNally, Shamil Rupani, Fatema Juma, Sarah Catherine Mills, Laura Muirhead, Kate Sellars, Una Walsh, Oliver Warren, Alice Chambers, Richard Hunt, Stephen Boyce, Hannah Cornwall, Isabel Tol, Eleftherios Orestis Argyriou, Nicola Eardley, Meical Povey, Joanna M S Aithie, Ahmer Irfan, Mari-Claire McGuigan, Robert Starr, Craig Russell Warren, Jess Archibald, Georgia Kirby, Ivan Kisyov, Chun Kheng Khoo, Rachel Lee, Dana Photiou, Rowan Davis, Uday Prasad, P Zichu Yang, Jonathan Bird, Edmund Leung, Virginia Summerour, Chelise Currow, Jianshen Kiam, Gerald Jack Soon Tan, Anitha Muthusami, Ibifunke Pegba-Otemolu, Tomas Urbonas, Joseph Nunoo-Mensah, Edgaras Smolskas, Alex Boddy, Gianpiero Gravante, David Hunter, David Andrew, Amanda Koh, Amari Thompson, Lawrence Adams, Hollie A Clements, Kasun De Silva, Ogbonnia Ekpete, Seraj Haque, Scott Henderson, Bilal Ibrahim, Thummini Jayasinghe, Jennifer Livie, Keir Mailley, Gopikrishnan Nair, Daniel Tan, Caitlin Baggaley, Aleksander Dawidziuk, Bartosz Szyszka, Charlotte Barter, Nirav Gandhi, Karen Hassell, Samantha Hitchin, Jennett Kelsall, Eva Nagy, Ashrafun Nessa, Lisa Whisker, Fady Yanni, Mahmoud Ali, Deeksha Arora, Sunanda Hediwattege, Navam Kumarasinghe, Munir Rathore, Athula Tennakoon, Syed Mustafa Ali Ahmad, Oreoluwa Bajomo, Fahema Nadira, Valerio Celentano, Ewen Griffiths, Rama Santhosh Karri, Jason Kei Chak Mak, Michelle Pipe, Muhammad Iqbal Bhatti, Mohamed Rabie, Connor Boyle, David Hamilton, Aishath Mihuna, James Chean Khun Ng, Gary Nicholson, Agata Oliwa, Robert Pearson, Anna Rose, Shun Qi Yong, Catherine Boereboom, Michael Hanna, Catherine Walter, Thomas Samuel Greensmith, Rachel Mitchell, Eimear Monaghan, James Crawford, Susan Moug, James Blackwell, Hannah Boyd-Carson, Philip Herrod, Omar Al-Allaf, Miriam Beattie, Cameron Bullock, Shivang Burman, Gemma Clark, Nicolas Flamey, Oliver Flannery, Alexander Harding, Ben Kodiatt, Samuel Lawday, Shivani Mahapatra, Navin Mukundu Nagesh, Michael Ng, Dupinderjit Rye, Andrel Yoong, Laura Clark, Chris Deans, Monisha Edirisooriya, Emma Victoria Carrington, Tsz Lun Ernest Wong, Baasil Yusuf, Carla Chamberlain, Kathryn Duke, Elizabeth Kmiotek, Azel Botes, Natalie Condie, Timothy Schrire, Reena Shah, Iolo Thomas-Jones, Charlotte Yates, Natasha Anthony, Edward Matthews, Kapil Sahnan, James Tankel, Sally Tucker, Jasmine Winter Beatty, Paul Ziprin, William Duggan, Anastasia Kantartzi, Shruthi Sridhar, Rachel Alys Khaw, Prakhar Srivastava, Charlotte Underwood, Homero Alves do Canto Brum, Sharat Chopra, Laura Davis, Rebecca Hughes, Joshua Tulley, Justin Alberts, Thomas Athisayaraj, Mojolaoluwa Olugbemi, Kasim Ahmad, Claudia Chan, Gavin Chapman, Hannah Fleming, Benjamin Fox, Julia Grewar, Kate Hulse, Duncan Rutherford, Mackay Sinead, Scott Smith, Doug Speake, Peter G Vaughan-Shaw, Natasha Christodoulides, Simrit Kudhail, Matthew Welch, Syed Muhibullah Husaini, Simon Lambracos, Chikamuche Anyanwu, Rishi Suresh, Jimmy Scott Thomas, Elizabeth Gleeson, Rebecca Platoff, Areeba Saif, Zachary Enumah, Eric Etchill, Alodia Gabre-Kidan, Mitchell Bernstein, Francesco Maria Carrano, Joseph Connors, Patricio Lynn, Marcovalerio Melis, Elliot Newman, Deshka S Foster, Kenneth Perrone, Ashley Titan, Sarwat Ahmad, Andrea Chao M.D. Bafford, Marco Dal Molin, Nader Hanna, Syed Nabeel Zafar, Mark Hemmila, Lena Napolitano, Jane J Wong, Julia Chandler, Lauren Wood, Sherry Wren, Taylor Ottesen, Lucia You, Kristin Yu, María del pilar Arciénega Yañez, Martin Ferreira Fernandes, Daniel González, Santiago Cubas, María Catalina González, Vanessa Zubiaurre, Rodrigo Demolin, Nicolas Giroff, Pablo Sciuto, Maite Campos, Gabriela Rodríguez Cantera, Garg Deepika, Elliot Simuchimba, Anadi Bulaya, Chali Chibuye, Bright Chirengendure, Mary-Rose Kabale, Kizito Kabongo, James Munthali, Oliver Mweso, Francis Pikiti, James Otieno, Log Tung Lai, Brighid Blackman, Sophie Richards, Suren Subramaniam, Rafid Karim, Nathan Kok, Yanni Dion Lee, Shabina Ali, Aanjaneya Sinha, Robert Corrigan, Nicole Barnes, Florence Wong, Grace Dennis, Julia Jedamzik, Emil Phillips, Wivine Piette, Marie Van hentenryck, Houenoukpo Koco, Souliath Lawani, Mamo Woldu Kassa, Tainá Santos Bezerra, Petar Gribnev, Dobromir Dimitrov, Panche Krastev, Sovannarith Oum, Divine Tim Bonghaseh, Maryam Al Farsi, Nourah Alsharqawi, Veronica Acevedo, Andrea Carolina Castillo Barbosa, Felipe Giron, Jimmy Paul Leon Rodriguez, Darko Kucan, Damir Rosko, Neven Barsic, Domagoj Župan, Amgad Hegazi, Vendula Truncíková, Vladimir Fryba, Mostafa Mohamed, Ahmed Sultan, Ahmed Nagi, Abdallah Rashad Temerik, Mohamed Elemam Elshawy, Moustafa Ibrahim Mahmoud, Shrouk Omar, Mohamed Anwar, Tarek Rageh, Aya Elmokadem, Khaled Gaballa, Sandra Teppo, Antti Turunen, Pasi Pengermä, Quentin Ballouhey, Damien Bergeat, Ariane Weyl, Elisabeth Hain, Adam Gyedu, Edwin Yenli, Dorcas 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Castilla Moreno M.A., Genov G., Ilieva I., Ivanov T., Karamanliev M., Khan A., Mitkov E., Yotsov T., Atanasov B., Belev N., Slavchev M., Nsengiyumva C., Jones E., Stock S., Kyota S., Brown J., Mabanza K. T., Nigo Samuel L., Otuneme C., Prosper N., Umenze F., Boutros M., Caminsky N., Dumitra S., Garfinkle R., Morency D., Salama E., Banks A., Ferri L., He H., Katz A., Liberman A.S., Meterissian S., Pang A., Parvez E., Hameed U., Osman F., Sequeira S., Coburn N., Jaffer A., Karanicolas P., Mosseler M., Musselman R., Liu X., Yip C.W., Garces-Otero J.S., Guzman C., Sierra S., Uribe Valencia A., Cabrera Rivera P.A., Camelo S., Gonzalez A., Gonzalez-Orozco A., Mosquera Paz M.S., Perez Rivera C.J., Gonzalez F., Isaza-Restrepo A., Nino- Torres L., Arias Madrid N., Mendoza Arango M.C., Tsandiraki J., Jemendzic D., Kocman B., Suman O., Canic R., Jurisic D., Karakas I., Krizanovic Rupcic A., Pitlovic V., Samardzic J., Kopljar M., Bacic I., Domini E., Karlo R., Miljanic D., Simic A., Ahmed M., Al Nassrallah M., Altaf R., Amjad T., Eltoum R., Haidar H., Hassan A., Khalil O., Qasem M., Ramesh R., Sajith G., Wisal M., Zatecky J., Bujda M., Jirankova K., Paclik A., Abdallah A., Abdulgawad Almogy M., Ayman El-sawy E., ElFayoumy A.M., Elghareeb N., Esmat N.A., Fadel A., Habater A., Hamdy H., Hefni A., Kamal M., Mohamed Abobakr N., Sayed A., Shaker N., Taha E., Tharwat H., Zakaria O., Abdelmotaleb I., Al-Dhufri A., Al-Himyari H.S., El sheikh E., Eldmaty A., Elkhalawy A., M.Elkhashen A., Magdy K., Mostafa S., Sadia H.D., Saleh M.M., Samir D., Yahia Mohamed Ali M., A. Nassar M., Abdelhady S., Abdelrazek A., Abdelsalam I., El-Sawy A., Essam E., Gadelkarim M., Ghaly K., Hassabalnaby M., Masarani R., Mohamed Shaaban N., Sabry A., Salem M., Soliman N.A., Zahran D., Abou El.soud M.R., Badr E.T., Borham H., Elmeslemany N., Elsayed M., Elsherif F., Eslam S., Gaber G., Ibrahim S., Kamh Y., Mohamed S.G., Morshedy E., Omar C., Salem Soliman F., Abdelkawy S., Abdelmohsen N., Abdelshakour M., Dahy A., Gamal N., Gamal M., Hasan A., Hetta H., Mousa N., Omar M., Rabie S., Saad M., Saleh B., Sayed Mohamed M., Shawqi M., Abdelhady Mousa H., Alnoury M., Elbealawy M., Elshafey A., Essam Ibrahim El Desouki Muhammad Ahmed M., Ghonaim M., Hgag F., Ibrahim M., Morsy M., Reda Loaloa M., Refaat A., Samir H., Shahien F., Sobhy M., Sroor F., Abdellatif E., Adel M., Afifi A.A., Afifi E., Antaky M., Dawoud A., El Zoghby N., El-remaily A., Elzanfaly A.A., Gadallah A., Gamal F.A., Hashem O., Medhat Youssef S., Muhammad Attyah A., Munir M., Shazly O., Wilson K., Adel S., Ali A., 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S., Alherz M., Ather M., Bajilan M., Graziadei V., Pilkington I., Quidwai O., Ridgway P., Shiwani H., Tahir A.A.-R., Blunnie E., Burke D., Kennedy N., Macdonagh K., O'Neill M., Rooney S., Falco G., Ferrari G., Mele S., Nita G.E., Ugoletti L., Zizzo M., Confalonieri G., Pesenti G., Tagliabue F., Baronio G., Ongaro D., Pata G., Compagnoni B., Salvadori R., Taglietti L., D'Alessandro N., Di Lascio P., Pascale G., Bortolasi L., Campagnaro T., Carlini M., Lisi G., Lombardi D., Pedrazzani C., Spoletini D., Turri G., Violi P., Altomare D.F., Aquilino F., Musa N., Papagni V., Picciariello A., Vincenti L., Andreotti D., Occhionorelli S., Tondo M., Basso S.M.M., Cirelli R., Maino M.E.M., Piozzi G.N., Picone E., Scaramuzzo R., Sinibaldi G., Amendola A., Anastasio L., Bucci L., Caruso E., Castaldi A., Di Maso S., Dinuzzi V.P., Esposito G., Gaudiello M., Giglio M.C., Greco P.A., Luglio G., Manfreda A., Marra E., Mastella F., Pagano G., Peltrini R., Pepe V., Sacco M., Sollazzo V., Spiezio G., 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G., Morshedy, E., Omar, C., Salem Soliman, F., Abdelkawy, S., Abdelmohsen, N., Abdelshakour, M., Dahy, A., Gamal, N., Gamal, M., Hasan, A., Hetta, H., Mousa, N., Omar, M., Rabie, S., Saad, M., Saleh, B., Sayed Mohamed, M., Shawqi, M., Abdelhady Mousa, H., Alnoury, M., Elbealawy, M., Elshafey, A., Essam Ibrahim El Desouki Muhammad Ahmed, M., Ghonaim, M., Hgag, F., Ibrahim, M., Morsy, M., Reda Loaloa, M., Refaat, A., Samir, H., Shahien, F., Sobhy, M., Sroor, F., Abdellatif, E., Adel, M., Afifi, A. A., Afifi, E., Antaky, M., Dawoud, A., El Zoghby, N., El-remaily, A., Elzanfaly, A. A., Gadallah, A., Gamal, F. A., Hashem, O., Medhat Youssef, S., Muhammad Attyah, A., Munir, M., Shazly, O., Wilson, K., Adel, S., Ali, A., Eid, E., Elhelow, E., Elmahdy, M., Elshatby, B., Hossam el-din Zakaria, A., Hossny, A., Ibrahim, E., M. 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G., Hussein, M., Kandil, A. A., Moawad, M., Nasser Hamamah, A. A., Soliman, M., Abdelkhalek, M., Abdelmaksoud Tawakel, N., Abdelwahed, A. M., Abdou, A., Atallah, K., Elsherbeny, M. Y., Emara, E., Hamdy, M., Hamdy, O., Haron, A., Ismail, S., Metwally, I. H., Mohamed Hamed Elgaml, N., Nassar, A., Refky, B., Sadek, M., Saleh, M., Yunes, A., Zakaria, M., Zuhdy, M., Fayed, N., Mohammed, M. M. H., Kutner, S., Melnik, P., Seire, I., Umarik, T., Ainoa, E., Eerola, V., Koppatz, H., Koskenvuo, L., Sallinen, V., Takala, S., Katunin, J., Turunen, A., Christou, N., Mathonnet, M., Lavoue, V., Nyangoh Timoh, K., Soulabaille, L., Lesourd, R., Merdrignac, A., Sulpice, L., Andre, B., Chantalat, E., Vaysse, C., Dousset, B., Gaujoux, S., Martin, G., Clonda, O., Juodis, D., Kienle, K., Mravik, A., Palmer, S., Szabadhegyi, G., Agbeko, A. E., Gyabaah, S., Gyamfi, F. E., Naabo, N., Owusu senior, A., Yorke, J., Owusu, F., Abantanga, F., Anyomih, T. T. K., Muntaka, A. -J. M., Owusu Abem, E., Sheriff, M., Wondoh, P. M., Balalis, D., Korkolis, D., Gkiokas, G., Pantiora, E., Theodosopoulos, T., Ioannidis, A., Konstantinidis, K., Konstantinidou, S., Machairas, N., Paspala, A., Prodromidou, A., Chouliaras, C., Papadopoulos, K., Baloyiannis, I., Mamaloudis, I., Tzovaras, G., Akrida, I., Argentou, M. -I., Germanos, S., Iliopoulos, E., Maroulis, I., Skroubis, G., Theofanis, G., Chatzakis, C., Ioannidis, O., Loutzidou, L., Karathanasis, P., Michalopoulos, N., Theodoropoulos, C., Theodorou, D., Triantafyllou, T., Garoufalia, Z., Hasemaki, N., Kontos, M., Kouraklis, G., Kykalos, S., Liakakos, T., Mpaili, E., Papalampros, A., Schizas, D., Syllaios, A., Tampaki, E. C., Tsimpoukelis, A., Antonopoulou, M. I., Deskou, E., Manatakis, D. K., Papageorgiou, D., Zoulamoglou, M., Anthoulakis, C., Margaritis, M., Nikoloudis, N., Campo, V., Ceballos, A., Flores, M. -A., Giron, W., Ko, D., Martinez, G., Rivera Lara, V., Rueda, N., Sanchez, A., Tejeda Garrido, J. C. 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M., Rodriguez Gonzalez, A., Chachaima Mar, J. E., Chinchihualpa Paredes, N. O., Cuba, V., Lopez, W., Niquen Jimenez, M. M., Sanchez Bartra, N. A., Sapallanay Ojeda, O., Sequeiros, D., Toscano Pacheco, A., Vergara, M., Abarca, S., Alcorta, R., Borda-Luque, G., Eusebio Zegarra, I. E., Lujan Lopez, C., Marrufo, M., Mogrovejo, C., Nomura, A., Rodriguez Angeles, Y., Vidal Meza, M. R., Zavala, G., Castillo Arrascue, J. N., Hidrogo Cabrera, J. C., Larrea vera, J. J. M., Osorio, M., Ylatoma Diaz, E. A., Fontanilla, M. A., Fuentes, J. R., Salazar, A. L., Dominguez, G., Lopez, M. P., Macalindong, S., Onglao, M. A., Ramirez, A., Sacdalan, M. D., Tampo, M. M., Uy, G. L., Mangahas, J., Yabut, K., Canete, J. P., Cansana, B. E., Castro, E. J., Lipana, M. K., Roxas, M. F., Zara, V. 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P., Cagigas Fernandez, C., Castanedo Bezanilla, S., Estevez Tesouro, J., Fernandez-Diaz, M. J., Garcia Cardo, J., Gomez Ruiz, M., Gonzalez-Tolaretxipi, E., Jimeno Fraile, J., Poch, C., Rodriguez-Aguirre, M., Troche Pesqueira, N., Trugeda-Carrera, M. S., de la Torre, J., Blanco-Colino, R., Espin-Basany, E., Espinosa-Bravo, M., Morales Comas, C., Reyes Afonso, E., Rivero Deniz, J., Siso Raber, C., Verdaguer Tremolosa, M., Chandrasinghe, P., Kumarage, S., Wijekoon Arachchilage, N., Abdalla Ahmed Elkamel, A., A. Adam, M., Blomme, N., Thorell, A., Wogensen, F., Alga, A., Ansarei, D., Celebioglu, F., Heinius, G., Nigard, L., Pieniowski, E., Ahlqvist, S., Bjorklund, I., Franberg, A., Hakansson, M., Adamo, K., Franklin, O., Sund, M., Wiberg, R., Andersson, Y., Chabok, A., Nikberg, M., Kugelberg, A., Canonica, C., Christoforidis, D., Fasolini, F., Gaffuri, P., Giuliani, M., Meani, F., Popeskou, S. G., Pozza, S., Wandschneider, W., Peterer, L., Widmer, L. 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Akram, Zahran, Diaaaldin, Abou El Soud, Moustafa Ramadan, Badr, Esraa Tarek, Borham, Hala, Elmeslemany, Nehal, Elsayed, Mohammad, Elsherif, Fawzia, Eslam, Sara, Gaber, Gehad, Ibrahim, Sondos, Kamh, Yara, Mahmoud, Abdelrahman, Mohamed, Shimaa Gamal, Morshedy, Eman, Omar, Cinderella, Salem Soliman, Fatima, Abdelkawy, Shaza, Abdelmohsen, Naglaa, Abdelshakour, Mahmoud, Dahy, Ahmed, Gamal, Norhan, Gamal, Mohammed, Hasan, Ahmad, Hetta, Helal, Mousa, Nehad, Omar, Mohamed, Rabie, Somia, Saad, Mahmoud, Saleh, Bakeer, Sayed Mohamed, Marwa, Shawqi, Muhammad, Abdelhady Mousa, Heba, Alnoury, Mostafa, Elbealawy, Mohamed, Elshafey, Ahmed, Essam Ibrahim El Desouki Muhammad Ahmed, Muhammad, Ghonaim, Mennatullah, Hgag, Fawzy, Ibrahim, Mohamed, Morsy, Mahmoud, Reda Loaloa, Mohamed, Refaat, Ahmed, Samir, Hadeer, Shahien, Fatma, Sobhy, Mohamed, Sroor, Fathy, Abdellatif, Esraa, Adel, Marina, Afifi, Amr Abdelghani, Afifi, Eman, Antaky, Marco, Dawoud, Amr, El Zoghby, Naira, El-Remaily, Amira, Elzanfaly, Ali Abdelazez, Gadallah, Ahmed, Gamal, Fatma Alzahraa, Hashem, Omar, Medhat Youssef, Shrouk, Muhammad Attyah, Aliaa, Munir, Malak, Shazly, Omar, Taha, Esraa, Wilson, Karim, Adel, Sawsan, Ali, Asmaa, Eid, Esraa, Elhelow, Esraa, Elmahdy, Marwa, Elshatby, Bassant, Hossam El-Din Zakaria, Amany, Hossny, Ahmad, Ibrahim, Eman, M Yonis, Ahmed, Metwalli, Maram, Yousry, Basant, Zid, Esraa, A Yacoub, Mina, Abdelhakim, Ahmed, Abouelsoad, Nervana, Alkhatib, Mo'min, Ashraf, Ahmed, Ashraf, Alaa, Elazab, Yasmin, Elfanty, Mahmoud, Elkabir, Osama, Elsayed, Mai, Elshimy, Ahmed, Elsobky, Hager, Eskander, John, Gad, Ahmed, Hamsho, Ward, Khaled Abdelwahed, Noura, Magdy, Menna, Moharam, Dalia, Osama, Abeer, Ramadan, Shereen, Roum, Radwa, Sayed, Taqwa, Shehada, Tarneem, Zidan, Ahmed Mohy, Abbas, Khalid, Ali, Amr, Attia, Mohamed, Balata, Mohamed, El Nakeeb, Ayman, Elewaily, Mohamed Ibrahim Elsayed, Elfallal, Ahmed, Elfeki, Hossam, Elkhadragy, Ahmed, Emile, Sameh, Ezzat, Helmy, Hosni, Hasnaa, Mansour, Islam, Omar, 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Athisayaraj, Thomas, Olugbemi, Mojolaoluwa, Ahmad, Kasim, Chan, Claudia, Chapman, Gavin, Fleming, Hannah, Fox, Benjamin, Grewar, Julia, Hulse, Kate, Rutherford, Duncan, Sinead, Mackay, Smith, Scott, Speake, Doug, Vaughan-Shaw, Peter G, Christodoulides, Natasha, Kudhail, Simrit, Welch, Matthew, Husaini, Syed Muhibullah, Lambracos, Simon, Anyanwu, Chikamuche, Suresh, Rishi, Thomas, Jimmy Scott, Gleeson, Elizabeth, Platoff, Rebecca, Saif, Areeba, Enumah, Zachary, Etchill, Eric, Gabre-Kidan, Alodia, Bernstein, Mitchell, Carrano, Francesco Maria, Connors, Joseph, Lynn, Patricio, Melis, Marcovalerio, Newman, Elliot, Foster, Deshka S, Perrone, Kenneth, Titan, Ashley, Ahmad, Sarwat, Bafford, Andrea Chao M D, Dal Molin, Marco, Hanna, Nader, Zafar, Syed Nabeel, Hemmila, Mark, Napolitano, Lena, Wong, Jane J, Chandler, Julia, Wood, Lauren, Wren, Sherry, Ottesen, Taylor, You, Lucia, Yu, Kristin, Arciénega Yañez, María Del Pilar, Ferreira Fernandes, Martin, González, Daniel, Cubas, Santiago, González, María Catalina, Zubiaurre, Vanessa, Demolin, Rodrigo, Giroff, Nicolas, Sciuto, Pablo, Campos, Maite, Rodríguez Cantera, Gabriela, Deepika, Garg, Simuchimba, Elliot, Bulaya, Anadi, Chibuye, Chali, Chirengendure, Bright, Kabale, Mary-Rose, Kabongo, Kizito, Munthali, James, Mweso, Oliver, Pikiti, Francis, Otieno, James, Lai, Log Tung, Blackman, Brighid, Richards, Sophie, Subramaniam, Suren, Karim, Rafid, Kok, Nathan, Lee, Yanni Dion, Ali, Shabina, Sinha, Aanjaneya, Corrigan, Robert, Barnes, Nicole, Wong, Florence, Dennis, Grace, Jedamzik, Julia, Phillips, Emil, Piette, Wivine, Van Hentenryck, Marie, Koco, Houenoukpo, Lawani, Souliath, Kassa, Mamo Woldu, Santos Bezerra, Tainá, Gribnev, Petar, Dimitrov, Dobromir, Krastev, Panche, Oum, Sovannarith, Bonghaseh, Divine Tim, Al Farsi, Maryam, Alsharqawi, Nourah, Acevedo, Veronica, Castillo Barbosa, Andrea Carolina, Giron, Felipe, Leon Rodriguez, Jimmy Paul, Kucan, Darko, Rosko, Damir, Barsic, Neven, Župan, Domagoj, Hegazi, Amgad, Truncíková, Vendula, Fryba, Vladimir, Mohamed, Mostafa, Sultan, Ahmed, Nagi, Ahmed, Rashad Temerik, Abdallah, Elshawy, Mohamed Elemam, Mahmoud, Moustafa Ibrahim, Omar, Shrouk, Anwar, Mohamed, Rageh, Tarek, Elmokadem, Aya, Gaballa, Khaled, Teppo, Sandra, Turunen, Antti, Pengermä, Pasi, Ballouhey, Quentin, Bergeat, Damien, Weyl, Ariane, Hain, Elisabeth, Gyedu, Adam, Yenli, Edwin, Osei-Poku, Dorcas, Rompou, Vaia-Aliki, Zoikas, Athanasios, Gaitanidis, Apostolos, Koukis, Georgios, Perivoliotis, Konstantinos, Tavlas, Panagiotis, Galanos-Demiris, Konstantinos, Zografos, George, Karavokyros, Ioannis, Xanthopoulou, Georgia, Iordanidou, Eirini, Ayau, Fernanda, Garcia, Allan, Damján, Pekli, Wason, Deepender, B L, Ashika, Rangganata, Ervandy, Kamath, Prerna, O'Connor, Donal B, Pinto, Margherita, Perrone, Fabrizio, Tropeano, Francesca Paola, Troilo, Francesca, Bossi, Daniela, Scala, Dario, Pulitanò, Lucrezia, Carella, Marcella, Pietrabissa, Andrea, Gori, Alice, Giraudo, Giorgio, De Simone, Veronica, Russo, Alfio Alessandro, Braccio, Bartolomeo, Al-Taher, Raed, Athamneh, Sarah, Parker, Andrea, Sawiee, Adnan, Kattia, Amina, Salem, Malik, Tababa, Osama, Shaeeb, Zuhour, Syminas, Vilius, Jurgaitis, Jonas, Damuleviciene, Gyte, Svagzdys, Saulius, Poskus, Tomas, Razafimanjato, Narindra Njarasoa Mihaja, Chieng Loo, Ling, Tiong, Ing Ching, Wan Muhmad, Wan Farahiyah, Vijeyan, Harinthiran, Li Ying, Teoh, Grech, Gabriella, Arrangoiz, Rodrigo, Jimenez Ley, Vania Brickelia, Arizpe, Daniel, Lagunes Lara, Elizabeth, Castro López, Elizabeth Victoria, Eaazim, Jose, Gordinou de Gouberville, Marije, Bastiaenen, Vivian, Rottier, Simone, Nahab, Fouad, Ji, Maria Yeonhee, Seyoji, Mohammed, Nwachukwu, Callistus, Emeghara, Okechukwu, Muhammed, Sayyid Egbunu, Idowu, Ayodeji, Sowemimo, Olamiposi, Ogundoyin, Olakayode, Akande, Oluwatosin, Lott, Alexander, Nadeem, Maliha, Laghari, Ahsan Ali, Loya, Asif, Mushtaq, Hassan, Abdullah, Muhammad Tariq, Abuhilal, Baseel, Atawneh, Mohammad, Hamdan, Hamdan, Alhabil, Belal, Srour, Abedelrahman, Mousa, Ibrahim, Da Silva Medina, Luis, Bartosiak, Katarzyna, Ferreira, Pedro, Francisco, Vítor, Lemos, Ricardo, Frutuoso, Luísa, Fernandes, Sara, Fonseca, Telma, Pereira, Jorge, Rachadell, Juan, Torre, Ana, Madeira Martins, Filipe, Carvalho, Ana Cristina, Rodrigues Ferreira, Joana, Ribeiro da Silva, Bruno, Devesa, Helena, Vieira, Ana, Mónica, Inês, Amaro, Margarida, Sousa, Diogo, Reia, Marta, Louro, João, Martins, Ana, Dominguez, Joaquina, Santos, Inês, Freitas Oliveira, Nuno Miguel, Pereira, José Carlos, Silva-Vaz, Pedro, Freire, Ligia, Escrevente, Ricardo, Negoita, Valentina Madalina, Shakhmatov, Dmitry, Nezerwa, Yves, Radulovic, Radosav, Obery, Gareth, Viljoen, Francois, Mendes, Tome, Suarez, Antonio, Moncada, Enrique, Fernandez-Hevia, Maria, Curtis Martínez, Carolina, Gil Garcia, Julia Maria, González Zunzarren, Mariana, Idris, Tarig, Eklöv, Karolina, Grahn, Oskar, Amin, Leila, Blomqvist, Malin, Ajani, Costanza, Kraus, Rebecca, Seeger, Nico, Willemin, Melissa, Rayya, Fadi, Ayash, Mohammad, Msouti, Raneem, Kannas, Israa, Abazid, Eias, Esper, Asil, Slim, Skander, Kavcar, Akil Serdar, Aytac, Erman, Dural, Ahmet Cem, Ilker, Ayse, Eray, Ismail Cem, Kurnaz, Eray, Altiner, Saygin, Tepe, Mustafa Deniz, Sahin, Can, Savli, Evrim, Innocent, Aryon, Babirye, Lilian, Diachenko, Andrii, Hordoskiy, Vladislav, Curry, Heather, Chau, Charlene Yat Che, Robertson, Harry, Mahmoud, Arin, Lennon, Hannah, Loi, Lynette, Kirkham, Emily, McCann, Cameron, Watts, Daniel, Gurung, Binay, Wilson, Michael, Tribedi, Thomas, Garofalo, Eleonora, Zahra, Baryab, MacDonald, Scott, Daniels, Ian, Ng, Nathan, Khosla, Shivun, Olivier, James, Yue, Sum Yu Pansy, Suresh, Gayathri, Wellington, Jack, Lorejo, Emmanuel, Mossaad, Mafdi, Crutcher, Madison, Alimi, Marjan, Baiu, Ioana, Abdou, Hossam, Conway, Alison, Peck, Connor, Perdomo Perez, Mauro Andres, Zulu, Stanley, Nakazwe, Mildred, Burger, Sule, Davies, Justine, Donaldson, Rachel, Ede, Chikwendu, Garden, O James, Lesetedi, Chiapo, Mabedi, Charles, Magill, Laura, Makinde Alakaloko, Felix, Makupe, Alex, Monahan, Mark, Mulira, Soloman, Muller, Elmi, Musowoyo, Jospeh, Olory-Togbe, Jean Léon, Roberts, Tracey, Smith, Martin, Tayler, Viki, Windsor, John, Yepez, Raul, Sundar, Sudha, Runigamugabo, Emmy, Verjee, Azmina, Chen, José, Daya, Leonid, El Aroussi, Nouhaila, Farina, Valeria, Gnintedeme Olivier, Tchianze, Gonzales Nacarino, Mauricio, Hammani, Aamr, Honjo, Sarah, Jacobs, Rebecca, Kimura, Hitomi, Nkoronko, Mugisha, Oscullo Yepez, Jasson Javier, Pin Hung, Wei, Raj, Ankit, Romani Pozo, Alina, Rommaneh, Muna, Sassamela Fabiano, Samuel Chimbioputo, Shiroma Gago, Camila Milagros, Srinivas, Abhishekh, Sung, Chia-Yen, Tai, Aswan, Valle Aranda, Yener Cristyell, Venturini, Sara, and Wilguens Lartigue, Jean
Subjects: Pediatrics, Colorectal cancer, IMPACT, Disease, Colorectal Neoplasm, 030204 cardiovascular system & hematology, Cancer, surgery, postoperative mortality, 0302 clinical medicine, Postoperative Complications, Global health, 030212 general & internal medicine, Prospective Studies, Prospective cohort study, General Medicine, DISEASES, Income, cancer surgery, Colorectal Neoplasms, Breast Neoplasm, Cohort study, Human, Adult, Developed Countrie, medicine.medical_specialty, Global surgery, General surgery, International multicentre study, Cancer surgery, Breast Neoplasms, Department of Error, NO, Developing Countrie, 03 medical and health sciences, Breast cancer, Stomach Neoplasms, medicine, Humans, Developing Countries, Neoplasm Staging, business.industry, Developed Countries, Odds ratio, CARE, medicine.disease, 3126 Surgery, anesthesiology, intensive care, radiology, Prospective Studie, Postoperative Complication, business
Abstract: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Background: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit.
Published: 2021

23. THE USE OF TONGUE TWISTER TECHNIQUE TO IMPROVE STUDENTS’ PRONUNCIATION

Author: Hilda Hafid, Dzur Ri’fah, Abd Rajab, and Awalia Azis
Subjects: medicine.medical_specialty, education.field_of_study, Population, medicine, Audiology, Pronunciation, education, After treatment, Test (assessment), Mathematics, Tongue-twister
Abstract: The objective of this research was to find out whether the use of tongue twister technique can improve students’ pronunciation especially in pronouncing sound /ð/, /d/, /θ/, /t/, /ᶴ/, and /s/ or not.The method of this research was pre-experimental with pre-test and post-test as an instrument of the research. The population of the research was the eleventh grade of SMP 2 Sungguminasa that consisted of 63 students. The number of samples was 33 students. The data collection consisted of pre-test, treatment and post-test. Forms of pre-test and post-test were oral test that contained 18 words that related with the focus sounds.The findings of the research showed that the students’ mean score of pre-test before treatment was 63.09%. While after treatment, the mean score of post-test was 86.81%. Therefore, the significant between pre-test and post-test was 37.59%. In order that, the researcher assumed that using tongue twister technique could improve students’ pronunciation correctly especially in pronouncing sound /ð/, /d/, /θ/, /t/, /ᶴ/, and /s/.
Published: 2021

24. LDL/apo B ratio predict coronary heart disease in Type 2 diabetes independent of ASCVD risk score: A case-cohort study

Author: Yekta Rahimi, Soghra Rabizadeh, Alireza Esteghamati, Fatemeh Moosaie, Armin Rajab, Jeffrey I. Mechanick, and Manouchehr Nakhjavani
Subjects: Male, medicine.medical_specialty, Apolipoprotein B, Endocrinology, Diabetes and Metabolism, Medicine (miscellaneous), Coronary Disease, 030209 endocrinology & metabolism, Type 2 diabetes, Iran, 030204 cardiovascular system & hematology, Risk Assessment, Coronary artery disease, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Diabetes mellitus, Internal medicine, Prevalence, medicine, Humans, Risk factor, Aged, Dyslipidemias, Retrospective Studies, Nutrition and Dietetics, Framingham Risk Score, biology, business.industry, nutritional and metabolic diseases, Cholesterol, LDL, Middle Aged, Prognosis, medicine.disease, Glycemic index, Diabetes Mellitus, Type 2, Apolipoprotein B-100, biology.protein, Cardiology, Female, lipids (amino acids, peptides, and proteins), Metabolic syndrome, Cardiology and Cardiovascular Medicine, business, Biomarkers
Abstract: Coronary heart disease (CHD) is a major mortality risk factor in patients with diabetes. LDL cholesterol (LDL-C) is a major risk factor for the development of atherosclerosis. There is one apolipoprotein B (ApoB) molecule in each LDL particle. We aimed to evaluate the predictive value of the LDL-C/ApoB ratio for CHD in patients with type 2 diabetes (T2D).In this case-cohort study (apo)lipoproteins and glycemic indices were measured in 1058 individuals with T2D from February 2002 to March 2019, with a median duration of follow up of 10 years. Of 1058 patients with T2D, coronary heart disease occurred in 242 patients. Increased waist circumference, waist-to-hip ratio, and hemoglobin A1c, low-density lipoprotein cholesterol (LDL-C)/Apolipoprotein B (ApoB) ratio, presence of hypertension and metabolic syndrome, and insulin and statin use were more prevalent among patients with CHD (P 0.001). Logistic regression analysis showed that an LDL-C/ApoB ratio equal or lower than 1.2 could predict CHD independent of ASCVD risk score [adjusted OR:1.841, CI:1.257-2.698, P 0.001] when adjusted for multiple confounders. The atherogenic index of plasma (AIP) did not predict CHD.This study showed that LDL-C/ApoB ratio, but not the atherogenic index of plasma, may be considered as an indicator of CHD independent of the ASCVD risk score in patients with T2D. This finding merits further clarification to optimize preventive strategies for CHD.
Published: 2021

25. Effectiveness of an Otolaryngology Head and Neck Surgery Residents' Induction 'Boot Camp' in Saudi Arabia

Author: Fazal Hussain, Eulaf H. Alaadah, Alaeddin Jebreel, Fouad Jabri, Naif H. Alotaibi, Ibrahim S. Alnoury, Muataz H. Alhashem, and Mohammad Hasan Rajab
Subjects: Boot camp, medicine.medical_specialty, Otorhinolaryngology, business.industry, General surgery, medicine, Head and neck surgery, business
Abstract: Introduction The otolaryngology (ORL) boot camp was designed to onboard ORL residents through a curriculum focusing on their needs as novice otolaryngologists. This boot camp provided systematic, specialty-wide training in core elements of knowledge, procedural skills, professionalism, supervision, and communications for residents entering ORL. The present study aimed to assess the effectiveness of an ORL resident induction “boot camp” in the Kingdom of Saudi Arabia. Methods This was a cross-sectional (multicenter) study encompassing data collection through an online voluntary questionnaire. Participants were new ORL residents in the Saudi residency training program. Results Fifty responses were returned, with a completion rate of 88%. Sixty-four percent of the respondents were male. Most of the respondents were aged from 26 to 27 years. Respondents were from different cities. Most participants agreed that the scientific value of the course was beneficial (agree, 40%; strongly agree, 44%) and they felt better prepared for their residency training after this boot camp (agree, 44%; strongly agree, 28%). Conclusion Boot camp in ORL is an additional important activity during the early years of training. It provides significant effects in terms of knowledge readiness at the beginning of specialty training. We believe that boot camp should include other dimensions of training, including surgical, communication, and judgmental skills, not only for the early years of training but also during the remaining period until training completion.
Published: 2021

26. Heart transplantation following donation after cardiac death: History, current techniques, and future

Author: David N. Campbell, James Jaggers, and Taufiek Konrad Rajab
Subjects: Adult, Pulmonary and Respiratory Medicine, Heart transplantation, medicine.medical_specialty, Tissue and Organ Procurement, business.industry, medicine.medical_treatment, MEDLINE, Donation after cardiac death, History, 20th Century, History, 21st Century, Tissue Donors, Death, medicine, Heart Transplantation, Humans, Surgery, Cardiology and Cardiovascular Medicine, Intensive care medicine, business
Published: 2021

27. Effect of Stretching Exercises Plus Caflam on Flexibility of Female Athletes

Author: Abida Naseer, Sumeria Rajab, Fehmida Ayoob, Shahbaz Ahmad, Hira Shahid, Sajjad Ali Gill, Samaviya Noor, Rana Adil, Saeed Javed, and Qurban Ali
Subjects: medicine.medical_specialty, Flexibility (anatomy), biology, Proprioception, business.industry, Athletes, biology.organism_classification, Dynamic stretching, medicine.anatomical_structure, Paired samples, Sit and reach test, Physical therapy, Medicine, Controlled experiment, business, Stretching exercises
Abstract: The present study investigated how stretching exercises (Static, Dynamic and Proprioceptive neuromuscular facilitation (PNF)) along with Caflam (diclofenac potassium) affect the flexibility of female athletes at Punjab University Level. It is a controlled experiment with (n=40) female athletes, aged 18-24 years, divided into two groups intervention (N=30) and control group (N=10) randomly. Stretching exercises were conducted through 6 weeks divided into two sessions that consisted of both static and dynamic exercises in each session. Flexibility was measured with sit and reach test in pre and post evaluation sessions. The study purpose was to identify the effect of stretching exercises on flexibility of female athletes (N=40) by using different stretching exercises techniques (static and dynamic stretching exercises) on female athletes. Paired sample t-test used and found that it showed highly significant results using “Statistical Package for Social Sciences” (SPSS) V.22 utilized. The effect size was also calculated through Cohans’D which was 1.41. The subjects were followed for 4 months to check the recurrence rate of the control & intervention groups and found that 19% having injuries of lower extremity (control group) and 11% having after post-exercise evaluation (intervention group).
Published: 2021

28. Assessment of the relationship between depression and treatment compliance in chronically-ill patients in Jeddah, Saudi Arabia

Author: Somayah Saeed Bawazeer, Joud Jamal Balkhair, Aroub Adel Rajab, and Ameen Almohammadi
Subjects: medicine.medical_specialty, business.industry, Treatment adherence, Pharmaceutical Science, Medication adherence, Disease, Chronic illness, Depression, Medication adherence, Treatment compliance, medicine.disease, Moderate depression, Mild depression, Treatment compliance, Internal medicine, Hyperlipidemia, medicine, Pharmacology (medical), business, Depression (differential diagnoses)
Abstract: Purpose: To find the relationship between depression, treatment adherence and lifestyle changes inchronically-ill patients residing in Jeddah, Saudi Arabia.Methods: A cross-sectional study was conducted. A self-administered questionnaire was used tocollect data from patients of multi-healthcare centers located in Jeddah. The questionnaire aimed tocollect the information regarding patients’ levels of medication compliance, patients’ capacity to copewith the disease and adherence to medication, along with their depression level.Results: Of the overall sample size of 439 patients, 43.1 % were suffering from hypertension, 37.8 %were diabetic and 33.7 % had hyperlipidemia. Besides, total scores of Patient Health Questionnaire-9(PHQ-9) showed that approximately 5 % patients were severely depressed, 8 % had moderately severedepression, 27 % had moderate depression, and 60 % had mild depression. Compliance scale datarevealed that 38 % patients showed low compliance, 51 % showed partial compliance, and 11 %showed high compliance. Also, a significant inverse relationship between depression and compliancescales (rs = -0.221, p = 0.004) was observed.Conclusion: The results show an inverse association between depression and medication adherencein patients with chronic disease in Jeddah. Therefore, clinicians are advised to assess the level ofdepression in chronically-ill patients in order to improve their adherence to medicine.Keywords: Chronic illness, Depression, Medication adherence, Treatment compliance
Published: 2021

29. Characteristics of pediatric maxillofacial fractures in Kuwait: A single‐center retrospective study

Author: Abdullah Algharib, Fahad Alsaad, Bashar Rajab, Hussein Hassan Hamed Ibrahim, and Ahmad M. AlAli
Subjects: Male, medicine.medical_specialty, Adolescent, Conservative management, Single Center, 03 medical and health sciences, 0302 clinical medicine, Mandibular Fractures, medicine, Humans, Child, Road traffic, Retrospective Studies, business.industry, Incidence (epidemiology), General surgery, Accidents, Traffic, Infant, Newborn, Infant, Retrospective cohort study, 030229 sport sciences, 030206 dentistry, Cross-Sectional Studies, medicine.anatomical_structure, Kuwait, Male patient, Child, Preschool, Etiology, Facial skeleton, Female, Maxillofacial Injuries, Oral Surgery, business
Abstract: BACKGROUND Pediatric maxillofacial fractures always present a challenge due to the unique nature of the facial skeleton anatomy and development. The aim of this study was to investigate the incidence, etiology, site of fracture, and management modalities of pediatric maxillofacial fractures in Kuwait. METHODS A retrospective cross-sectional study was conducted. The records of all pediatric patients who were diagnosed with maxillofacial fractures and admitted to one of the major hospitals in Kuwait between January 2007 and March 2020 were reviewed. RESULTS A total of 186 patients aged between 0 and 13 years old were included. An average of 13 patients was seen each year between 2007 and 2020. The leading cause of the pediatric maxillofacial trauma was road traffic accidents (RTA) that accounted for 38.2% of the patients followed by 22% falls from height (FFH). Male patients were more affected than females, with a ratio of 2.3:1. More than half of the children had mid-face fractures, of which 57% were in multiple sites. Conservative management was the main approach for 52.2% of the patients. CONCLUSIONS Pediatric maxillofacial fractures were mainly attributed to road traffic accidents in Kuwait. Mid-face bone fractures were reported more than mandibular fractures and were mostly managed conservatively.
Published: 2021

30. An eight-year multicenter study on short-term peripheral intravenous catheter–related bloodstream infection rates in 100 intensive care units of 9 countries in Latin America: Argentina, Brazil, Colombia, Costa Rica, Dominican Republic, Ecuador, Mexico, Panama, and Venezuela. Findings of the International Nosocomial Infection Control Consortium (INICC)

Author: Nepomuceno Mejia, Daisy Aguilar-de-Moros, Mohamed Rajab Abu-Jarad, Rayo Morfin-Otero, Daniela Vieira da Silva Escudero, Miguel Angel Altuzar-Figueroa, María Guadalupe Miranda-Novales, Blanca Estela Hernandez-Chena, Gabriela Di-Silvestre, Evelia Maria Diaz-Hernandez, Gustavo Jorge Chaparro, Esteban Gonzalez-Diaz, Elizabeth Castaño-Guerra, Julio C Mijangos-Méndez, Dayana Souza-Fram, Gabriel Munoz-Gutierrez, Eduardo Alexandrino Servolo-Medeiros, Jenia Johana Acebo-Arcentales, Victor D. Rosenthal, Eduardo Rodríguez-Noriega, Guadalupe Aguirre-Avalos, Federico Corona-Jiménez, José Guillermo Vázquez-Rosales, and Sandra M. Gualtero-Trujillo
Subjects: Costa Rica, Microbiology (medical), medicine.medical_specialty, Catheters, Latin Americans, Panama, Epidemiology, Argentina, Colombia, 030501 epidemiology, Meropenem, 03 medical and health sciences, Sepsis, Internal medicine, Intensive care, medicine, Humans, Prospective Studies, Mexico, Cross Infection, 0303 health sciences, biology, 030306 microbiology, business.industry, Mortality rate, Dominican Republic, Acinetobacter, Venezuela, biology.organism_classification, Nosocomial infection control, Intensive Care Units, Latin America, Infectious Diseases, Amikacin, Peripheral venous catheter, Ecuador, 0305 other medical science, business, Brazil, medicine.drug
Abstract: Background:Data on short-term peripheral intravenous catheter–related bloodstream infections per 1,000 peripheral venous catheter days (PIVCR BSIs per 1,000 PVC days) rates from Latin America are not available, so they have not been thoroughly studied.Methods:International Nosocomial Infection Control Consortium (INICC) members conducted a prospective, surveillance study on PIVCR BSIs from January 2010 to March 2018 in 100 intensive care units (ICUs) among 41 hospitals, in 26 cities of 9 countries in Latin America (Argentina, Brazil, Colombia, Costa Rica, Dominican-Republic, Ecuador, Mexico, Panama, and Venezuela). The Centers for Disease Control and Prevention (CDC) National Health Safety Network (NHSN) definitions were applied, and INICC methodology and INICC Surveillance Online System software were used.Results:In total, 10,120 ICU patients were followed for 40,078 bed days and 38,262 PVC days. In addition, 79 PIVCR BSIs were identified, with a rate of 2.06 per 1,000 PVC days (95% confidence interval [CI], 1.635–2.257). The average length of stay (ALOS) of patients without a PIVCR BSI was 3.95 days, and the ALOS was 5.29 days for patients with a PIVCR BSI. The crude extra ALOS was 1.34 days (RR, 1.33; 95% CI, 1.0975–1.6351; P = .040).The mortality rate in patients without PIVCR BSI was 3.67%, and this rate was 6.33% in patients with a PIVCR BSI. The crude extra mortality was 1.70 times higher. The microorganism profile showed 48.5% gram-positive bacteria (coagulase-negative Staphylococci 25.7%) and 48.5% gram-negative bacteria: Acinetobacter spp, Escherichia coli, and Klebsiella spp (8.5% each one), Pseudomonas aeruginosa (5.7%), and Candida spp (2.8%). The resistances of Pseudomonas aeruginosa were 0% to amikacin and 50% to meropenem. The resistance of Acinetobacter baumanii to amikacin was 0%, and the resistance of coagulase-negative Staphylococcus to oxacillin was 75%.Conclusions:Our PIVCR BSI rates were higher than rates from more economically developed countries and were similar to those of countries with limited resources.
Published: 2021

31. Health providers and irritable bowel syndrome

Author: Aishah Yahya Saeed Qatomah, Khalid Ayidh AlAmri, Wesam Mostafa Edrees, Wafa Yahya Saeed Qatomah, Mohammed Saleh Salem Alammari, Yahya Amer Ahmed Wadani, Sattam Awwadh Almalki, Nashmi Salom Aletesh, and Mohammad Rajab Alkhalaf
Subjects: Abdominal pain, medicine.medical_specialty, Constipation, business.industry, education, Stressor, Workload, Disease, medicine.disease, Diarrhea, Family medicine, Etiology, Medicine, medicine.symptom, business, Irritable bowel syndrome
Abstract: Irritable bowel syndrome (IBS) is the most commonly diagnosed condition, which accounts for the highest number of new referrals to gastroenterology clinics. The disease is characterized by symptoms, including diarrhea, abdominal pain, constipation, or a combination of both constipation and diarrhea, which could be accompanied by discharge of mucus in stool and changes in its appearance. The precise etiology of IBS and its pathophysiology are still unknown. However, it is believed that complex interactions between the hormonal, immune, and nervous systems are responsible for causing it. The prevalence of IBS varies across different regions globally, with the highest prevalence reported in South America (21%) and the lowest in Southeast Asia (7%). This review highlights several factors responsible for contributing to the development of IBS, among which stress was found to be an important factor. The current study observed an association between the increasing prevalence of IBS and stressful and hectic working conditions among healthcare professionals compared to the general public. General practitioners, family physicians, nurses, and dentists are exposed to several stressors due to their workload, resulting in an increased prevalence of IBS among healthcare professionals. Similarly, more stress is experienced by the medical students than the normal population because of the stressful academic environment. The review concludes that IBS is more prevalent among healthcare professionals and students, especially among female workers and students, than male workers and students.
Published: 2021

32. Impact of Fas/Fasl Gene Polymorphisms on Susceptibility Risk and Imatinib Mesylate Treatment Response in Chronic Myeloid Leukaemia Patients

Author: Ravindran Ankathil, Sarina Sulong, Nur Shafawati Ab Rajab, Mohd Ismail Ibrahim, Azlan Husin, Ahmad Aizat Abdul Aziz, Nazihah Mohd Yunus, and Aziati Azwari Annuar
Subjects: 0301 basic medicine, Oncology, Adult, Male, medicine.medical_specialty, Fas Ligand Protein, Adolescent, Genotype, FAS/FASL, Antineoplastic Agents, Lower risk, Fas ligand, resistance, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Polymorphism (computer science), Internal medicine, hemic and lymphatic diseases, imatinib mesylate, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Medicine, Humans, Genetic Predisposition to Disease, Allele, Child, Promoter Regions, Genetic, Chronic myeloid leukaemia, Aged, Retrospective Studies, Polymorphism, Genetic, business.industry, Malaysia, Cancer, General Medicine, Odds ratio, Middle Aged, medicine.disease, promoter polymorphism, 030104 developmental biology, Imatinib mesylate, Logistic Models, 030220 oncology & carcinogenesis, Female, business, Research Article
Abstract: Background: The FAS mediated apoptosis pathway involving the FAS and FASL genes plays a crucial role in the regulation of apoptotic cell death and imatinib mesylate (IM) mechanism of action. Promoter polymorphisms FAS-670 A>G and FAS-844 T>C which alter the transcriptional activity of these genes may grant a risk to develop cancer and revamp the drug activities towards the cancer cell. We investigated the association of these two polymorphisms with the susceptibility risk and IM treatment response in Malaysian chronic myeloid leukaemia (CML) patients. Methods: This is a retrospective study, which included 93 CML patients and 98 controls. The polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) method was used to genotype the FAS and FASL polymorphisms. Data nanlysis was done using SPSS Version 22. The associations of the genotypes with susceptibility risk and IM response in CML patients were assessed by means of logistic regression analysis and deriving odds ratio with 95% CI. Results: We observed a significant association between FASL-844T>C polymorphism and CML susceptibility risk and IM response. Variant C allele and FASL-844 CC variant genotype carriers had significantly higher risk for CML susceptibility (OR 1.756, CI 1.163-2.652, p=0.007 and OR 2.261, CI 1.013-5.047, p=0.047 respectively). Conversely, the heterozygous genotype FASL-844 TC conferred lower risk for CML susceptibility (OR 0.379, CI 0.176-0.816, p=0.013). The heterozygous and homozygous variant genotypes and variant C alleles were found to confer a lower risk for the development of IM resistance with OR 0.129 (95% CI: 0.034-0.489 p=0.003), OR 0.257 (95% CI: 0.081-0.818, p=0.021), and OR 0.486 (95% CI: 0.262-0.899, p=0.021) respectively. We also found that FAS-670 A>G polymorphism was not associated with CML susceptibility risk or IM response. Conclusion: The genetic polymorphism FASL-844 T>C may contribute to the CML susceptibility risk and also IM treatment response in CML patients. Accodringly, it may be useful as a biomarker for predicting CML susceptibility risk and IM resistance.
Published: 2021

33. Effect of an Educational Guideline about Gynecological Examination on Nurses' Knowledge and Practices

Author: Huda Abdulazim Elbnedari, Kamillia Rajab Abu Shabana, Mahmoud Salah Mahmoud Rady, and Nagat Salah Shalaby
Subjects: medicine.medical_specialty, business.industry, Family medicine, Nurses knowledge, medicine, Guideline, business, Gynecological Examination
Published: 2020

34. Immediate Postoperative Insulin Requirements May Predict Metabolic Outcome after Total Pancreatectomy and Islet Autotransplantation

Author: Philip Hart, Kristin Kuntz, Luis F. Lara, Amer Rajab, Sylvester M. Black, W. Kenneth Washburn, Shumei Meng, Kyle Porter, Neha Verma, Jill Buss, and Darwin L. Conwell
Subjects: Adult, Blood Glucose, Male, medicine.medical_specialty, Time Factors, Article Subject, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Islets of Langerhans Transplantation, Urology, Transplantation, Autologous, Diseases of the endocrine glands. Clinical endocrinology, Young Adult, Pancreatectomy, Endocrinology, Interquartile range, Insulin-Secreting Cells, Pancreatitis, Chronic, medicine, Humans, Hypoglycemic Agents, Insulin, Endocrine system, Ohio, Retrospective Studies, geography, geography.geographical_feature_category, business.industry, Retrospective cohort study, Middle Aged, RC648-665, medicine.disease, Islet, Autotransplantation, Treatment Outcome, Pancreatitis, Female, business, Biomarkers, Progressive disease, Research Article
Abstract: Chronic pancreatitis (CP) is a progressive disease that leads to eventual loss of endocrine and exocrine function. Total pancreatectomy and islet autotransplantation (TPIAT) is a treatment option for patients with CP; however, predicting postoperative metabolic outcomes remains elusive. In this single-center retrospective study, we report pre-TPIAT characteristics, beta cell function indices, islet yield, and post-TPIAT glucose management data to further understand their relationship. Islet yield, glucose level, and insulin requirement for 72 hours postoperatively were collected for a total of 13 TPIAT recipients between 9-2013 and 9-2018. In addition, their glucose control and basal insulin requirements at 3, 6, and 12 months post-TPIAT were analyzed. All 13 subjects had normal baseline fasting glucose levels. Median islet yield was 4882 IEq/kg (interquartile range 3412 to 8987). Median postoperative total insulin requirement on day 3 was 0.43 units/kg. Pre-TPIAT baseline glucose, insulin, or c-peptide level did not have a significant correlation with the islet yield. Similarly, there was no correlation between islet yield and insulin requirement at 72-hour postoperatively. However, there was an inverse correlation between the absolute islet yield (IEq) and insulin requirement at 6 months and 12 months following post-TPIAT. Further analysis of the relationship between 72-hour post-op insulin requirement and insulin requirement at discharge, 3, 6, and 12 months showed a positive correlation. Despite the finding of inverse correlation of islet yield with long-term basal insulin requirement, this study was not able to detect a correlation between the preoperative parameters to postoperative short-term or long-term outcome as noted in other studies. The 72-hour postoperative insulin requirement is a helpful postoperative predictor of patients needing long-term insulin management following TPIAT. This observation may identify a high-risk group of patients in need of more intensive diabetes education and insulin treatment prior to hospital discharge.
Published: 2020

35. Racial disparities in the incidence and survival of spinal meningioma

Author: Mahmoud Dibas, Mohammad J Atiah, Saadi Aljundi, Sherief Ghozy, Ahmad Mamoun Rajab, Nazmus Saquib, and Kevin Phan
Subjects: End results, medicine.medical_specialty, Future studies, business.industry, Incidence, Incidence (epidemiology), Large population, Retrospective cohort study, General Medicine, medicine.disease, survival, Meningioma, Internal medicine, Epidemiology, Medicine, Pacific islanders, Original Article, business, race, spinal meningioma
Abstract: Objective: Race is a significant prognostic factor in various cancers, including the breast. Its prognostic association with spinal meningioma has not been established, although the incidence of spinal meningioma varies by race. In this retrospective cohort study, we aimed to investigate the association of race with the incidence and survival of spinal meningioma among a large population sample. Materials and Methods: A comprehensive search was done in the surveillance, epidemiology, and end results database between 2000 and 2016 to identify patients with spinal meningioma. Overall and race-specific incidence were calculated. The effect of race on overall survival among these patients was determined with Kaplan–Meier curve and Cox proportional hazard models. Results: Of 3502 spinal meningioma patients, 82.6% were Caucasian, 7.7% were African-American, 8.8% were Asian/Pacific Islander and 0.7% were American Indian/Alaska Native. The overall age-adjusted incidence was 0.239/100,000; it was highest among Caucasian (0.249) and lowest among American Indian/Alaska Native patients (0.137). There was a race effect in overall survival in the unadjusted analysis with the worst overall survival reported for Caucasian patients, and the best reported for American Indian/Alaska Native patients. However, this relationship was insignificant in the adjusted analysis. Conclusions: Race was not significantly associated with overall survival among these patients. Future studies should use spinal-meningioma-specific survival as outcome to see whether there is a racial difference in survival.
Published: 2020

36. Thyroid neoplasm in Makkah region, Saudi Arabia

Author: Suhail I. Sayed, Omar A. Abu Suliman, Firas R. Abi Sheffah, Rajab Alzahrani, Haddad H. Alkaff, Sherif K. Abdelmonim, Saeed A. Al-Ghamdi, Ameen Z. Alherabi, Mohammad A. Alessa, Fares E. Alghamdi, Bayan O. Besharah, Osama A. Marglani, Deemah H. Bukhari, Anas H. Al-Tammas, John C. Heaphy, and Osama A. Bawazir
Subjects: Adult, Male, Makkah, medicine.medical_specialty, Pediatrics, Time Factors, Future studies, education, Saudi Arabia, 030204 cardiovascular system & hematology, medicine.disease_cause, thyroid, Thyroid carcinoma, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, parasitic diseases, Epidemiology, medicine, Humans, cancer, Thyroid Neoplasms, 030212 general & internal medicine, Thyroid tumors, Thyroid neoplasm, Retrospective Studies, business.industry, Incidence, Thyroid disease, Incidence (epidemiology), Thyroid, Age Factors, General Medicine, Middle Aged, medicine.disease, medicine.anatomical_structure, Head and Neck Neoplasms, Thyroid Cancer, Papillary, Female, Original Article, business, geographic locations, Follow-Up Studies
Abstract: Objectives: To improve our local data and demographics of thyroid neoplasm in Makkah region, Kingdom of Saudi Arabia and provide some basic statistics for future studies in our local community. Methods: A record based retrospective epidemiological study was conducted and included 314 thyroid disease patients who were presented to our centers at Makkah region, Kingdom of Saudi Arabia between December 2009 and December 2019. Results: A descriptive statistical analysis was carried out. The average age was 42.77 years, with a female-to-male ratio of 3:1, and most of the patients were Saudi (77%). Fifty-seven percent of cases were benign, while in malignant cases, 33.4% were papillary thyroid carcinoma. The mean follow-up time was 15.44 months, with excellent compliance in 39.4% of the patients. Conclusion: Thyroid tumors have a leading incidence in head and neck tumors in Makkah, Kingdom of Saudi Arabia, mandating further studies to determine the causes and distribution in other regions of the country.
Published: 2020

37. IMPROVEMENT IN REDOX HOMEOSTASIS AFTER CYTOREDUCTIVE SURGERY IN COLORECTAL ADENOCARCINOMA

Author: Soghra Rabizadeh, Giovanni Tomasello, Niloofar Najafi, Alireza Esteghamati, Manouchehr Nakhjavani, Armin Rajab, Abbas Alibakhshi, Hossein Mirmiranpour, Salome Sadat Salehi, Sadat Salehi,S, Mirmiranpour,H, Rabizadeh,S, Esteghmati,A, Tomasello,G, Alibakhshi,A, Najafi,N, Rajab,A, and Nakhjavani,M
Subjects: Glycation End Products, Advanced, Male, 0301 basic medicine, Aging, Antioxidant, Colorectal cancer, medicine.medical_treatment, medicine.disease_cause, Biochemistry, Gastroenterology, chemistry.chemical_compound, Postoperative Complications, 0302 clinical medicine, Malondialdehyde, Homeostasis, chemistry.chemical_classification, biology, Glutathione peroxidase, Cytoreduction Surgical Procedures, General Medicine, Middle Aged, Catalase, colorectal cancer, colorectal surgery, cytoreductive surgery, redox homeostasis, Lipoproteins, LDL, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, Research Article, Adult, medicine.medical_specialty, Article Subject, Adenocarcinoma, Superoxide dismutase, 03 medical and health sciences, Internal medicine, medicine, Humans, Aged, Glutathione Peroxidase, QH573-671, business.industry, Cell Biology, medicine.disease, Oxidative Stress, 030104 developmental biology, chemistry, biology.protein, Cytology, business, Oxidative stress, Lipoprotein
Abstract: Colorectal cancer (CRC) as one the most common cancer type is associated with oxidative stress. Surgery is the only curative modality for early-stage CRC. The aim of this study was to evaluate the oxidative damage biomarkers as well as enzymatic and nonenzymatic antioxidants in patients with CRC before and after tumor resection and in healthy controls. 60 patients with stage I/II colorectal adenocarcinoma and 43 healthy controls were recruited in this study. We measured plasma levels of oxidative damage biomarkers, including advanced oxidation protein products (AOPP), advanced glycation end products (AGEs), malondialdehyde (MDA), and oxidized low-density lipoprotein (ox-LDL) at baseline and after tumor removal. We also evaluated the plasma activity of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) as enzymatic antioxidants and the ferric reducing antioxidant power (FRAP) assay for nonenzymatic antioxidant capacity. Patients with CRC had significantly higher AGE, AOPP, MDA, and ox-LDL and also FRAP levels and higher SOD and GPx and lower CAT activity levels compared to healthy controls (p<0.05). We did not observe any statistically significant correlation between redox biomarkers and the size and stage of the tumor. AGEs (72.49±4.7vs.67.93±8.8,p<0.001), AOPP (137.64±21.9vs.119.08±33.1,p<0.001), MDA (3.56±0.30vs.3.05±0.33,p<0.001), and ox-LDL (19.78±0.97vs.16.94±1.02,p<0.001) concentrations reduced significantly after tumor removal. The largest effect sizes were found in ox-LDL (d=−2.853, 95% CI 2.50-3.19) and MDA (d=−1.617, 95% CI 0.43-0.57). Serum FRAP levels (1097.5±156.7vs.1239.3±290,p<0.001) and CAT (2.34±0.34vs.2.63±0.38,p<0.001), GPx (102.37±6.58vs.108.03±6.95,p<0.001), and SOD (5.13±0.39vs.5.53±0.31,p<0.001) activity levels increased significantly after surgery. The largest effect sizes among antioxidants were seen in SOD (d=1.135, 95% CI 0.46-0.34) and GPx (d=0.836, 95% CI 0.35-0.23). This study indicated that patients with colorectal cancer had higher levels of oxidative stress and antioxidant activity compared to healthy controls. After surgical resection of tumor, we observed a substantial improvement in redox homeostasis.
Published: 2021

38. Role of fine-needle aspiration cytology in evaluating thyroid nodules

Author: Firas R. Abi Sheffah, Sherif K. Abdelmonim, Ameen Z. Alherabi, Suhail I. Sayed, Haddad H. Alkaff, Mohammad A. Alessa, Omar A. Abu Suliman, Ahmed S. Bahaj, Anwar N. Melebari, Anas H. Al-Tammas, Saeed A. Al-Ghamdi, Osama A. Bawazir, Fares E. Alghamdi, Rajab Alzahrani, John C. Heaphy, Syeddah S. Mujtaba, Bashair N. Melebari, and Osama A. Marglani
Subjects: Adult, Male, Thyroid nodules, medicine.medical_specialty, Cytological Techniques, Saudi Arabia, Thyroid Gland, carcinoma, 030204 cardiovascular system & hematology, Sensitivity and Specificity, Tertiary care, thyroid, Tertiary Care Centers, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Fine needle aspiration cytology, medicine, Humans, Thyroid Neoplasms, Thyroid Nodule, 030212 general & internal medicine, skin and connective tissue diseases, Endoscopic Ultrasound-Guided Fine Needle Aspiration, Retrospective Studies, business.industry, General surgery, Thyroid, Retrospective cohort study, General Medicine, Middle Aged, medicine.disease, Aspiration cytology, body regions, medicine.anatomical_structure, FNA, cytology, Referral center, Female, Original Article, Ultrasonography, business
Abstract: Objectives : To evaluate the accuracy and e cacy of ne-needle aspiration cytology (FNAC) in diagnosing thyroid nodules, correlating it with the histopathological findings. Methods : A retrospective evaluation of 314 patients was undertaken at a tertiary referral center of King Abdullah Medical City (KAMC), Makkah, Kingdom of Saudi Arabia, between 2010-2019. Patients who presented with thyroid swellings underwent ultrasonography and FNAC. If indicated, surgery was performed. The FNAC findings were compared to the final histopathological reports. Results : Th e findings for FNAC from our data set of 314 patients showed a sensitivity value of 79.8%, specificity of 82.1%, accuracy of 74.8%, positive predictive value of 74.8%, and negative predictive value of 85.9%. Conclusion : Our study showed that FNAC has high sensitivity and speci city in the initial evaluation of patients with thyroid nodules. When guided by ultrasonography, the accuracy can be markedly improved. Molecular markers once widely available can improve the diagnostic power of FNAC to be no less than the histopathologic evaluation of thyroid tissue. Saudi Med J 2020; Vol. 41 (10): 1098-1103 doi: 10.15537/smj.2020.10.25417 How to cite this article: Ahmed S. Bahaj, Haddad H. Alka, Bashair N. Melebari, Anwar N. Melebari, Suhail I. Sayed, Syeddah S. Mujtaba, Sherif K. Abdelmonim, Saeed A. Alghamdi, Fares E. Alghamdi, Omar A. Abu Suliman, Mohammad A. Alessa, Firas R. Abi Sheffah, Anas H. Al-Tammas, Rajab A. Al-Zahrani, Osama A. Marglani, John C. Heaphy, Osama A. Bawazir, Ameen Z. Alherabi. Role of fine-needle aspiration cytology in evaluating thyroid nodules. A retrospective study from a tertiary care center of Western region, Saudi Arabia. Saudi Med J 2020; Vol. 41 (10): 1098-1103. doi: 10.15537/smj.2020.10.25417
Published: 2020

39. Transplantation in Fontan failure: The final stage

Author: James Jaggers and Taufiek Konrad Rajab
Subjects: medicine.medical_specialty, business.industry, medicine.medical_treatment, Protein losing enteropathy, Arteriovenous malformation, medicine.disease, Surgery, Transplantation, Ventricular assist device, medicine, Extracorporeal membrane oxygenation, Fontan failure, Stage (cooking), business
Published: 2020

40. Gluteal muscles primary hydatid cyst after cortical bone destruction in the sacrum

Author: Kusay Ayoub, Abdelaziz Alibraheem, Shaban Suliman, Ammar Niazi, Yasser Hendawi, Ahmad Al-Mouakeh, Mohammad Karam Abouzied, and Samer Rajab Basha
Subjects: musculoskeletal diseases, Foot drop, medicine.medical_specialty, Sacrum, Gait disorders, A Rare Case Report, 03 medical and health sciences, 0302 clinical medicine, Echinococcosis, parasitic diseases, medicine, Paresthesia, Echinococcus granulosus, Main text, Sciatica, biology, business.industry, General Medicine, Pelvic cavity, medicine.disease, biology.organism_classification, Low back pain, Hydatid disease, Surgery, medicine.anatomical_structure, 030220 oncology & carcinogenesis, 030211 gastroenterology & hepatology, medicine.symptom, Differential diagnosis, business
Abstract: Introduction Hydatid disease is caused by infection of Echinococcus Granulosus. Usually Hydatid Cysts occur in the liver and lungs. Presenting hydatid cysts in bone without hepatic affectation is rare and occurs in 0.5–2% of cases. Hence, this rare case makes the diagnosis difficult for the clinicians and, as a result, misdiagnosis of sacral Echinococcosis is common. Presentation of case The authors report on a 47-year male with primary sacral hydatidosis and 34 years of recurrence. He was admitted with compressive neurological symptoms like tingling pain, numbness, sciatica and foot drop. He has undergone 8 operations and has been treated with Albendazole. He has developed a Sacro-cutaneous fistula. Discussion When assessing sciatica, low back pain or lower limb weakness the pelvic cavity should be examined for hidden disease that might explain the neurological symptoms. Conclusion A missed diagnosis of osseous Hydatidosis could be devastating. Accordingly, the sacral Hydatid cyst must be included as a differential diagnosis for compressive neurological symptoms. In clinical practice, surgery remains the gold standard for treating osseous Hydatidosis., Highlights • The symptoms of osseous echinococcosis are non-specific and widely variable. • Sacral hydatid cyst it should be included in the differential diagnosis of any bone mass caused compressive neurological symptoms. • Treatment of hydatid cyst is primarily surgical, demanding total removal without rupture. • Posterior approach is preferred over anterior due to feasibility of the intervention and decrease of the recurrence rate.
Published: 2020

41. Thyroglossal duct surgery. What is the acceptable recurrence rate?

Author: Ameen Z. Alherabi, Firas R. Abi Sheffah, Anas H. Al-Tammas, Asma A. Alahmadi, Mohannad K. Rajab, Osama A. Bawazir, Abdullah Bawazir, Ibtihal A. Althobaiti, John C. Heaphy, and Osama A. Marglani
Subjects: Male, medicine.medical_specialty, recurrence, Adolescent, Thyroglossal duct, Biopsy, Fine-Needle, Saudi Arabia, lcsh:Medicine, 030204 cardiovascular system & hematology, Brief Communication, Malignancy, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, surgical, Biopsy, medicine, Humans, 030212 general & internal medicine, Child, sistrunk, Retrospective Studies, Duct cyst, medicine.diagnostic_test, business.industry, lcsh:R, Gold standard, Infant, Retrospective cohort study, General Medicine, medicine.disease, Thyroglossal Cyst, thyroglossal duct cyst, Surgery, Fine-needle aspiration, medicine.anatomical_structure, Research centre, Child, Preschool, Surgical Procedures, Operative, Female, business
Abstract: Objectives: To present experiences of different specialties in the treatment of thyroglossal duct cysts (TGDCs) and subsequent complications in multiple centers. Methods: A retrospective cross-sectional study of all cases of TGDC for a period of 11 years from 2008-2019 by different departments from 3 different centers in Jeddah, Kingdom of Saudi Arabia (King Faisal Specialist Hospital and Research Centre, Bakhsh Hospital and International Medical Center). Results: Forty-nine patients were included. The type of surgery performed plays a significant role in recurrence (p less than 0.001). The Sistrunk procedure had a lower recurrence rate (0%) than simple excision (70%) and has showed a significantly long recurrence-free interval (p less than 0.001). Higher recurrence rates are associated with higher postoperative complications (p=0.002). Patients who underwent pre-operative fine needle aspiration did not have any recurrence during the follow-up period. Conclusion: The Sistrunk procedure is the gold standard technique with the highest recurrence-free interval rate. Fine needle aspiration could be recommended as a less invasive procedure to exclude malignancy.
Published: 2020

42. The Effect of Oligopin Supplement on Systolic Blood Pressure in Women with Type 2 Diabetic Mellitus

Author: Reza Haji Hosseini, Koroush Rajab Khah, Razieh Bakhshandeh Amnieh, Manoochehrkhan Nakhjavani, Rasool Orouji, and Ali Hasan Shaban Khamseh
Subjects: medicine.medical_specialty, Blood pressure, business.industry, Internal medicine, Diabetic mellitus, medicine, Cardiology, business
Published: 2020

43. ABNORMAL FINDING OF PAP SMEAR AMONG WOMEN HOSPITAL VISITORS IN CITY OF MOSUL, IRAQ

Author: Thukaa T Yahya, Layla G Saeed, Wasnaa A Elias, and Sanaa Rajab
Subjects: Infertility, Vaginal discharge, medicine.medical_specialty, Intraepithelial neoplasia, Abdominal pain, business.industry, Obstetrics, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Abnormal PAP Smear, Obstetrics and gynaecology, 030220 oncology & carcinogenesis, Medicine, Abnormal Finding, 030212 general & internal medicine, medicine.symptom, business, Prospective cohort study
Abstract: Objective: The research aims to test the use of the Pap smear screening system to identify precancerous lesions among women in City of Mosul, Iraq. Methods: This prospective study was carried out over 1 year at the Department of Obstetrics and Gynaecology in Mosul Teaching Hospital, city of Mosul, Iraq. We screened 100 sexually active women who were more than 21 years of age. Women with different complaints, including vaginal discharge, blood‑mixed discharge, foul-smelling discharge, postcoital bleeding, intermenstrual bleeding, postmenopausal bleeding, abdominal pain, infertility, and secondary amenorrhea, were included in this study. The glass slides had been sent for cytopathological review to the pathology department. The laboratory results have been reported by the new Bethesda Cervical Cytology Reporting System 2014. The device divided the lesions narrowly into certain negative ones for intraepithelial neoplasia and with epithelial cell abnormalities (ECA) that involve squamous and glandular cells. Upon pap smear, the patient was treated accordingly. Results: The study had enrolled a total of 100 cases. All of these patients had an abnormal Pap smear finding that fell according to TBS-2014 criteria in the category of Epithelial Cell abnormality. We interviewed all patients in Detail by proforma. The data reported were statistically analyzed and were collected following observations and tests. Among the study subject, the most common abnormal findings (68.9%) were negative findings. Inflammatory constitute (15.4), and Atypical squamous cells of undetermined significance (7%) followed by LSIL (5.9) and HSIL (2.9). Conclusion: Pap smear is an effective method for screening for Cervical Lesions Precancerous and cancerous. Nevertheless, a cervical biopsy must be performed which Is gold standard if any epithelial defects are found to be confirmed in cervical cytology.
Published: 2020

44. Role of Hippocampal 5-HT6 Receptors in Glucocorticoid-Induced Enhancement of Memory Consolidation in Rats

Author: Rajab Mohamad Rezaei, Abbas Ali Vafaei, Nasroallah Moradi Kor, Seyed Ali Seyedinia, Ali Rashidy Pour, and Abdolhossein Shiravi
Subjects: 0301 basic medicine, Agonist, medicine.medical_specialty, medicine.drug_class, Hippocampal formation, inhibitory avoidance, lcsh:RC321-571, 03 medical and health sciences, Cellular and Molecular Neuroscience, chemistry.chemical_compound, 0302 clinical medicine, HT6 Receptor, Corticosterone, Internal medicine, medicine, Receptor, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, corticosterone, Antagonist, Receptor antagonist, 030104 developmental biology, Endocrinology, memory consolidation, chemistry, 5-ht6 receptor, Memory consolidation, Neurology (clinical), 030217 neurology & neurosurgery, Glucocorticoid, Research Paper, medicine.drug
Abstract: Introduction: of the study: Post-training administration of glucocorticoids enhance memory consolidation of inhibitory avoidance learning. Given the involvement of 5-HT6 receptors in memory processing and the interaction of glucocorticoids with the brain serotonergic system in modulating memory processing, we investigated whether the effect of glucocorticoids on the consolidation of emotionally arousing training depends on hippocampal 5-HT6 receptors. Methods: Rats were trained in an inhibitory avoidance task and immediately received the systemic injections of corticosterone (CORT) as well as the intra-hippocampal injections of 5-HT receptors agonist or antagonist. The memory retention test was done 48 hours after training and immediately after the behavioral test, the animals were sacrificed and the hippocampi (left and right) rapidly dissected out for molecular studies. Results: Post-training injections of different doses of CORT (1.25, 2.5, 5, and 10 mg/kg) enhanced memory retention in a dose-dependent manner. The CORT-induced enhancement of memory consolidation was blocked by bilateral intra-hippocampal injections of 5-HT6 receptor antagonist SB271046 (5 or 10 ng/per side), but not agonist EMD386088 (5 or 10 ng/per side). Furthermore, systemic CORT reduced 5-HT6 receptor mRNA and protein expression in the hippocampus. Both doses of 5-HT6 receptor agonist and antagonist significantly enhanced and reduced the expression of the 5-HT6 receptor, respectively, and both ligands at the higher dose (10 ng) enhanced memory consolidation. Moreover, CORT injection attenuated and enhanced, respectively, the effects of agonist and antagonist on 5-HT6 receptor expression. Conclusion: These behavioral and molecular findings indicated an interaction between glucocorticoids and hippocampal 5-HT6 receptors in the consolidation of emotionally arousing experiences.
Published: 2020

45. Characteristics and Causes of Neonatal Mortality in Hospitalized Cases at Benghazi Children's Hospital (2013-2014)

Author: Suad F. Elnasfi, Amal Elfakhri, Sami A. Lawgaly, Hind K. Elgetaany, Abeer Eltigane, Raja Elfakhri, and Ashraf M. Rajab
Subjects: Pediatrics, medicine.medical_specialty, Neonatal mortality, business.industry, Applied Mathematics, medicine, Neonatal death, business
Abstract: Background: Neonatal morbidity and mortality are major global public health challenges with approximately 3.1 million babies worldwide dying each year in the first month of life. The vast majority of neonatal death occurs in developing countries. Aims: This study was undertaken to assess the magnitude of neonatal mortality and identify the main causes and associated factors of neonatal mortality. Methodology: A retrospective study of 5791 neonates was conducted in Benghazi children hospital from 1st January 2013 up to December 2014. Results: During the two years of the study there were 5791 neonates admitted to neonatal unit of Benghazi hospital, out of them 389 died (6.7% of total neonatal admissions) accounting for 59.6% of the total Paediatric deaths within the same period, moreover approximately one neonate died every 48 hours throughout the study period. There was a slight predominance of male deaths 225 (57.5%) over females 164 (42.5%). The majority of neonates were Libyan 365 (94%), 212 of them were born in Benghazi, while the remaining 177 from other cities. Preterm neonate accounted for 35% (138) of deceased neonates. The most common causes were lung diseases of prematurity (29%), sepsis (25%), Congenital Heart Diseases (12.5%), post-operative intestinal obstruction (7%), multiple congenital anomalies (7%), intractable convulsions (6.5%). Conclusion: This study indicated that neonatal mortality represented the highest portion of all deaths reported at Benghazi children hospital during the study period. Lung diseases of prematurity was found to be the top leading cause followed by sepsis then congenital heart diseases. Male showed marginal predominance over female in this study. More than one third of deceased neonates were preterm.
Published: 2020

46. Nitric oxide and TNF-α are correlates of diabetic retinopathy independent of hs-CRP and HbA1c

Author: Manouchehr Nakhjavani, Soghra Rabizadeh, Alireza Esteghamati, Reihane Qahremani, Armin Rajab, Mohammad Omidi, Pegah Khaloo, Ghasem Farahmand, Firouzeh Heidari, Hossein Mirmiranpour, and Masoume Bitaraf
Subjects: medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Inflammation, Type 2 diabetes, Nitric Oxide, Gastroenterology, Nitric oxide, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Internal medicine, Diabetes mellitus, medicine, Humans, Glycated Hemoglobin, Diabetic Retinopathy, Triglyceride, Tumor Necrosis Factor-alpha, business.industry, Type 2 Diabetes Mellitus, Diabetic retinopathy, medicine.disease, C-Reactive Protein, Diabetes Mellitus, Type 2, chemistry, 030220 oncology & carcinogenesis, medicine.symptom, business, Biomarkers, Retinopathy
Abstract: Regarding the role of inflammation in progression of diabetes this study was conducted to investigate the association between inflammatory biomarkers such as nitric oxide (NO), tumor necrosis factor alpha (TNF-α), and high-sensitivity C-reactive protein (hs-CRP) with the chance of existence of diabetic retinopathy and its progression in patients with diabetes. A total of 83 patients with T2DM (Type 2 diabetes mellitus) were divided into three groups of patients with proliferative diabetic retinopathy (PDR), patients with non-proliferative diabetic retinopathy (NPDR) and patients without diabetic retinopathy (NDR) based on ophthalmologic funduscopic examination. Twenty six healthy controls were also enrolled. Blood samples were taken after 12 h of overnight fasting, NO, TNF-α, and hs-CRP were measured. Association of the level of these biomarkers with retinopathy was analyzed. The levels of TNF-α, NO and hs-CRP were higher among patients with diabetic retinopathy. Multinomial Logistic Regression model showed that TNF-α and NO could predict the presence of retinopathy among patients with diabetes when adjusted for hs-CRP, HbA1c, FBS, gender, total cholesterol, triglyceride, HDL, LDL, BMI, and age (respectively OR = 1.76, CI 95% = 1.01–3.02, p = 0.046 and OR = 1.12, CI 95% = 1.05–1.18, p
Published: 2020

47. Substance use disorders in Saudi Arabia: a scoping review

Author: Abdulrahman Almazrou, Nazmus Saquib, Juliann Saquib, and Ahmad Mamoun Rajab
Subjects: medicine.medical_specialty, lcsh:Social pathology. Social and public welfare. Criminology, Substance-Related Disorders, Saudi Arabia, 030508 substance abuse, Comorbidity, Review, Substance use disorder, Severity of Illness Index, lcsh:HV1-9960, 03 medical and health sciences, 0302 clinical medicine, Recurrence, Risk Factors, Medicine, Humans, 030212 general & internal medicine, Social work, business.industry, Health Policy, Public health, lcsh:Public aspects of medicine, lcsh:RA1-1270, medicine.disease, Mental health, Quality, Substance abuse, Psychiatry and Mental health, Health psychology, Cross-Sectional Studies, Scale (social sciences), Family medicine, Case-Control Studies, Family Relations, 0305 other medical science, business, Qualitative research, Primary research
Abstract: BackgroundSubstance use disorders (SUD) are mental health conditions that arise from chronic drug use. There is an increased recognition of this problem in Saudi Arabia.ObjectiveConduct a comprehensive review of published literature on SUD to identify knowledge gaps and to guide future research.MethodsPubMed, Embase and Cochrane databases were searched with suitable keywords for SUD publications up to June 10, 2019. Eligible studies (primary research conducted in Saudi Arabia) were organized into three broad domains: (1) risk (or protective) factors of SUD, (2) perspectives on drug use of people who use drugs, and (3) impact on family. The quality of the included studies was assessed with the Newcastle-Ottawa Scale.ResultsOf the 113 search records, 23 were eligible for analysis (19 cross-sectional and 4 case-control). All studies were conducted in clinical settings; all but two included males only. There were 4 studies about SUD risk factors, 6 studies about the perspectives of people who use drugs, and none about family impact. None of the cross-sectional studies (0%) and 25% of case-control studies were of good quality.ConclusionsThe available studies were few in number, weak in methodology, and poor in quality. Quantitative as well as qualitative studies about SUD are warranted in each domain and should represent both genders.
Published: 2020

48. C-reactive protein in gallbladder diseases: diagnostic and therapeutic insights

Author: Matthew S. Nelson, Mihee L. Choe, Jenna M. B. Addams, Margaret E. Olson, Ibraheem M. Rajab, Daniel Majerczyk, and Lawrence A. Potempa
Subjects: Pathology, medicine.medical_specialty, Gallbladder disease, Inflammation, 02 engineering and technology, Excretion, 03 medical and health sciences, chemistry.chemical_compound, medicine, 030304 developmental biology, 0303 health sciences, biology, Cholesterol, business.industry, Gallbladder, C-reactive protein, General Medicine, Gallstones, 021001 nanoscience & nanotechnology, medicine.disease, Biomarker (cell), medicine.anatomical_structure, chemistry, biology.protein, medicine.symptom, 0210 nano-technology, business
Abstract: The gallbladder is an important component of the hepatobiliary system whose primary function is to aid in digestion of foodstuffs, excretion of drugs and facilitate removal of waste products from the body. The gall bladder is principally a storage organ for bile, chemically modified salts and acids of cholesterol which are synthesized in the liver and which function as surfactants to solubilize fatty substances of limited aqueous solubility. Any disruption in the amount or activity of bile surfactant can lead to an accumulation of insoluble molecular clumps (e.g., gallstones) that deposit in and obstruct fluid movement within the gallbladder, and which can lead to pathological congestion and tissue damage. The natural host defense response to any event that causes tissue damage is to stimulate inflammation, which non-specifically but aggressively reacts to the stimuli so to remove the cause and repair damaged tissues. The C-reactive protein (CRP) is a primarily hepatically produced serum protein whose blood levels increase within 6–10 h of any tissue-damaging event. The extent with which it increases correlates with the level of tissue damage and associated inflammation. CRP levels are reported to be of value in diagnosing acute cholecystitis severity, in predicting the outcome and prognosis of cancer-associated gallbladder resection, and in helping identify cystic structures during emergency laparoscopic cholecystectomies. As an understanding of distinctive CRP structural isoforms is evolving, its role not only as a biomarker but as regulator of both physiologic and pathophysiologic processes of inflammation may be relevant in the understanding of and treatment approaches for gallbladder-associated disease.
Published: 2020

49. Perception of Pathology of Otolaryngology-Related Subjects: Students’ Perspective in an Innovative Multidisciplinary Classroom

Author: Ihab Shafek Atta and Rajab Alzahrani
Subjects: medicine.medical_specialty, Pathology, media_common.quotation_subject, Teaching method, education, Education, Dreyfus model of skill acquisition, Test (assessment), Formative assessment, Otorhinolaryngology, Multidisciplinary approach, Perception, medicine, Psychology, Curriculum, media_common
Abstract: Aim Multidisciplinary, as a term, is used to define people from different scientific backgrounds working together, each drawing on their field of expertise. Some related terms are frequently used interchangeably, such as interdisciplinary and transdisciplinary, but they are confusing and ambiguous. Introduction of a multidisciplinary teaching method in the early phases of medical curricula is insufficient for effective learning. Here, we aim to implement a multidisciplinary approach in the early phase of medical education and identify outcomes. Methods Two groups were evaluated in this study, each representing phases II and III of the Albaha medical curriculum, and including 90 and 86 students, respectively. "Hearing tests and their clinical applications" was selected as a subject to evaluate the understanding of special senses as studied by the phase II group, while "pathology of otolaryngology-related tumors and clinical correlations" was selected as a subject to evaluate the understanding of otolaryngology as studied by the phase III group. These subjects were selected by faculty members from otolaryngology, pathology and physiology departments and taught in successive stations. Teaching sessions were followed by a formative test that included 10 multiple-choice questions and a mini-clinical evaluation exercise (mini-CEX). A questionnaire to evaluate student satisfaction was completed after the exam. Results Students' satisfaction for the "hearing tests and their clinical applications" and "pathology of otolaryngology-related tumors and clinical correlations" subjects were 80% and 90.5%, respectively. The formative assessment revealed good student performance at 63.28%, and 60.46% of all students in both phases attained scores above 80%. Conclusion Introduction of a multidisciplinary approach early in the medical curriculum improves knowledge and skill acquisition. This is reflected in student performance, especially if evaluated using the mini-CEX format, thus providing rapid feedback to students concerning their performance.
Published: 2020

50. Effectiveness of Solution-based Therapy on Self-Compassion and Reducing Blood Glucose in Elderly Patients with Type 2 Diabetes

Author: Zari Ahmadi, Asadollah Rajab, Biouk Tajeri, and Saeideh Bazzazian
Subjects: medicine.medical_specialty, business.industry, Medicine, Blood sugar, Research article, Type 2 diabetes, business, Intensive care medicine, medicine.disease, Self-compassion
Abstract: Introduction and Objectives: One of the problems of diabetes in the elderly is the likelihood of another condition that makes it more difficult to control blood sugar. This study aimed to investigate the effectiveness of solution-based therapy on self-compassion and blood glucose reduction in elderly patients with type 2 diabetes. Materials and Methods: This quasi-experimental study was conducted based on a pretest-posttest design with a control group and follow-up. The statistical population of the study consisted of 60-75-year-old patients with type 2 diabetes referring to Iranian Diabetes Association treatment centers in Tehran, Iran. A total of 36 patients were selected and randomly assigned into two groups of experimental and control. The data were collected using a self-compassion questionnaire and glycated hemoglobin test (HbA1c). The HbA1c test was also administered two months after the end of the training to follow-up and evaluate the sustainability of the treatment effects. The data were analyzed in SPSS software (version 26) through repeated measure ANOVA. Results: The results showed that the solution-based therapy increased self-compassion in the posttest phase (P
Published: 2020

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