1. Time-varying serum albumin levels and all-cause mortality in prevalent peritoneal dialysis patients: a 5-year observational study
- Author
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Li-Chueh Kuo, Chien-Hsing Wu, Hong-Tao Yang, Jin-Bor Chen, Yang-Yang Lei, Pei-Ying Wang, Ben-Chung Cheng, Cheng-Hong Yang, Na Hao, Mei-Chen Chao, and Sin-Hua Moi
- Subjects
Adult ,Male ,Nephrology ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Peritoneal dialysis ,030232 urology & nephrology ,Serum albumin ,030204 cardiovascular system & hematology ,lcsh:RC870-923 ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Cause of Death ,Internal medicine ,medicine ,Humans ,Mortality ,Serum Albumin ,Aged ,Retrospective Studies ,biology ,business.industry ,Albumin ,Hazard ratio ,Middle Aged ,lcsh:Diseases of the genitourinary system. Urology ,Confidence interval ,Cohort ,biology.protein ,Kidney Failure, Chronic ,Female ,Observational study ,business ,Research Article - Abstract
Background In this study, we investigated the association of time-varying serum albumin levels with mortality over a 5-year period in one cohort of patients undergoing long-term peritoneal dialysis (PD) therapy. Methods The participants in this study enrolled 302 patients who underwent long-term PD at a single PD center in Taiwan. We reviewed medical records from 2011 to 2015 retrospectively. Time-averaged albumin level and serum albumin reach rate (defined as the percentage of serum albumin measurements that reached ≥3.5 g/dL) were applied as the predictor variables in the first 2 years (2011–2012). All-cause mortality was used as the outcome variable in the subsequent 3 years (2013–2015). Hazard function of all-cause mortality in the study participants was examined by using Cox proportional hazard regression models . Results Patients with different albumin reach rates (75–
- Published
- 2019