1. The Association Between Inflammatory Biomarkers and Vitamin D Level With the Evolution and Severity of Stroke
- Author
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Afshin Borhani-Haghighi, Anahid Safari, and Nima Fadakar
- Subjects
Oncology ,Cellular and Molecular Neuroscience ,medicine.medical_specialty ,business.industry ,Internal medicine ,medicine ,Vitamin D and neurology ,cardiovascular diseases ,Neurology (clinical) ,medicine.disease ,business ,Stroke ,Inflammatory biomarkers - Abstract
Introduction: Vitamin D deficiency has been linked to the evolution of ischemic stroke, but the data regarding the association between stroke severity and vitamin D level is scarce. Methods: Patients with first-ever ischemic stroke in the middle cerebral artery territory, within seven days after the stroke, were recruited. The control group included age- and gender-matched individuals. We compared 25-OH vitamin D (vitamin D), high sensitive C-reactive protein (hsCRP), serum amyloid A (SAA), and osteopontin levels between stroke patients and the control group. The association between stroke severity according to the National Institutes of Health Stroke Scale (NIHSS) and the Alberta stroke program early CT score (ASPECTS) and levels of vitamin D and inflammatory biomarkers were also studied. Results: There was an association between hypertension (P=0.035), diabetes mellitus (P=0.043), smoking (P=0.016), history of ischemic heart disease (P=0.002), higher SAA (P
- Published
- 2022