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8 results on '"Kosaku NAGAI"'

1. [Usefulness of 7 day therapy with cefluprenam in the management of respiratory tract infections]

Author

Kaoru SHIMADA, Mitsuhide OHMICHI, Hiroko SASAKI, Akira WATANABE, Kazuo SATO, Kosaku NAGAI, Kazuki KONISHI, Takashi OHTA, Yoshifumi MATSUURA, Hideki IKEDA, Kenichi IGARASHI, Fumihide IWATA, Koichi WADA, Michio MARUYAMA, Shigeyuki HOSHINO, Akira IWASHIMA, Yasutoshi SUZUKI, Osamu SEKINE, Nobuki AOKI, Saburo IZUMI, Toshio NAKAMURA, Toshiki IWABUCHI, Harumi SHISHIDO, Shoko TANOUE, Yuko KOMASE, Iwao SAKURAI, Kenji KASAI, Hiroyuki TERAWAKI, Michihiro TSUKUI, Keita HIRANO, Hiroyuki TANIGUCHI, Junya IKUTA, Akira YAMAGISAWA, Kunihiko GOTOH, Masashi YAMAMOTO, Mitsuo SATO, Akihisa KUMASAWA, Takashi SONODA, Jiro OKIMOTO, Makoto KIMURA, Hirohide YONEYAMA, Takayuki KARINO, Kazue FUJITA, Hideo OHBA, Takashi TSUYA, Akimasa OHUNE, Kohya SHIBA, Akira SAITOH, Hiroyuki KOBAYASHI, Toshiharu MATSUSHIMA, and Shigeru KOHNO

Subjects
Adult, Male, medicine.medical_specialty, Time Factors, medicine.drug_class, Cephalosporin, Ceftazidime, chemistry.chemical_compound, Internal medicine, Cefluprenam, medicine, Potency, Humans, Intensive care medicine, Infusions, Intravenous, Respiratory Tract Infections, Aged, Respiratory tract infections, business.industry, Incidence (epidemiology), Bacterial pneumonia, General Medicine, Middle Aged, medicine.disease, Rash, Cephalosporins, chemistry, Female, medicine.symptom, business, medicine.drug
Abstract

Efficacy and safety of a newer injectable cephalosporin, cefluprenam (CFLP) on cases with bacterial pneumonia and chronic respiratory tract infections were evaluated at a dose of 1g (potency), d.i.d for 7 days. 1. Of 130 cases in total, 116 cases were enrolled for the clinical efficacy evaluation. The efficacy rate (excellent and good responses) was 94.8% (110/116). The efficacy rate was 93.8% (60/64) for cases with bacterial pneumonia, and 96.2% (50/52) for cases with chronic respiratory tract infections. The recurrence was noted in 1.2% (1/82). The bacteriological response rate was 100.0% (32/32) for gram positive cocci, 93.8% (15/16) for gram negative rods and 97.9% (47/48) in total. 2. Adverse drug reactions were noted in 3.9% (5/129), consisting of 2 cases with skin rash, 1 case with drug fever, 1 case with skin rash and skin itching and 1 case with drug fever and headache. The abnormal laboratory changes were noted in 23.6% (30/127), mainly containing the elevation in GPT and GOT, and eosinophylia. The safety rate (no problem evaluation) was 74.8% (95/127). 3. The usefulness rate (very useful and useful evaluations) was 93.1% (108/116). As suggested by the evaluation on the secondary endpoint in the phase III comparative studies with both bacterial pneumonia and chronic respiratory tract infections, it was confirmed that the 7 day therapy of CFLP was promising for treatment of moderate bacterial pneumonia and chronic respiratory tract infections, because the high clinical efficacy was obtained and also the incidence of allergic reactions with CFLP was almost the same as that of ceftazidime (CAZ) evaluated highly safe. Based on these results, it was concluded that CFLP was useful in the management of moderate respiratory tract infections and also the recommended therapeutic period with CFLP was within 7 days.

Published
1997

2. [A comparative study between cefpirome (CPR) and ceftazidime (CAZ) in respiratory tract infections]

Author

Rinzo SOEJIMA, Masaru SUMI, Jiro HINO, Niro OKIMOTO, Yoshikazu KAWAKAMI, Etsuro YAMAGUCHI, Tsugio TERAI, Takashi YOSHIKAWA, Kazuo TAKAOKA, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Hidetoshi SHIBAKI, Koji TANEICHI, Tsuyoshi KIKUIRI, Masahide SHINOHARA, Akira MIWA, Choei ITO, Mitsuo SATO, Akira SUZUKI, Yasuhito HONDA, Kyuichiro SEKINE, Yomei HIRAGA, Mitsuhide OMICHI, Shinya YASUDA, Tetsuji KOROKU, Susumu ITO, Shoji KASAGI, Sokichi ONODERA, Yoshinobu OSAKI, Hiroyuki MATSUMOTO, Takafumi OTA, Eiichi SAKAI, Tetsuo SHIMIZU, Nobuhiro SASAKI, Toshiaki FUJIKANE, Satoshi FUJIUCHI, Toshiaki SHISHIDO, Kazuo TAKEBE, Atsuko YANADA, Mitsuo MASUDA, Seiichi MURAKAMI, Kenichi IMAMURA, Toyokazu TAMURA, Katsumi ENDO, Hideya MURABAYASHI, Shigeru OCHIAI, Hidekazu SAWADA, Michitaka SHIMURA, Masashi TAMURA, Kazuki KONISHI, Taiji YOSHIDA, Morio SUDO, Takeshi BANDO, Nobuhisa SATO, Masayuki OURA, Tetsuro UNOURA, Takashi MOURI, Tamotsu TAKISHIMA, Yasuo TANNO, Kunio KUDO, Munehiko ISHII, Masaharu SUGIYAMA, Masakichi MOTOMIYA, Akira WATANABE, Kosaku NAGAI, Kazuo SATO, Kiyoshi KONNO, Teruo HASUIKE, Kuniharu SHIDA, Satoshi SHINDO, Izumi HAYASHI, Jingoro SHIMADA, Masaki YOSHIDA, Atsushi SAITO, Koya SHIBA, Masanobu KAJI, Seiji HORI, Osamu SAKAI, Hideo MIYASHITA, Yasuo ONO, Masumi BABA, Hiroyuki KOBAYASHI, Hiroshi OSHITANI, Hiroshi MIURA, Takashi INOUE, Kaoru SHIMADA, Mieko GOTO, Hajime GOTO, Yasuyuki SANO, Yasufumi MIYAMOTO, Yasuo ARAI, Kanzaburo MATSUMURA, Yoshitaka NAKAMORI, Koji NARUI, Masayuki NOGUCHI, Tatsuo NAKATANI, Koichiro NAKATA, Iwao SAKURAI, Takeo IMAI, Fumio MATSUMOTO, Shigeki ODAGIRI, Masanori MATSUMURA, Kaneo SUZUKI, Kou MUROHASHI, Hiroshi TAKAHASHI, Kenichi TAKAHASHI, Teruaki YOSHIOKA, Izumi KOYAMA, Takashi OGURA, Masaaki ARAKAWA, Koichi WADA, Takashi KAWASHIMA, Masanaga TAKATO, Hidenori KUMANO, Nobuki AOKI, Tatsuo SATAKE, Kenichi YAMAKI, Ryujiro SUZUKI, Kenzo TAKAGI, Hitoshi TANAKA, Masatoshi IMAI, Toshiaki TSUNODA, Yoshiaki WATANABE, Toshihiko TAKEUCHI, Yoshimitsu HAYASHI, Kazuhide YAMAMOTO, Yasuo YAMADA, Fumiyuki KUZE, Takako MURAYAMA, Katsuhiro SUZUKI, Motokazu KATO, Masaru CHIBA, Riyo YAMAGUCHI, Hitoshi NAGAI, Fumikazu UMEDA, Hiromi TOMIOKA, Osamu EBISUI, Hironobu IWASAKI, Kenji BANDO, Takashi NISHIMURA, Tatsuki OYAIZU, Sunao ISHIDA, Shunsaku OHSHIMA, Masao KADO, Hirotaka YASUBA, Kikuo SUGIMOTO, Seibun YONEZU, Yoshihiro UEDA, Kojiro YASUNAGA, Fumio MIKI, Eiro TSUBURA, Masaru NAKAGAWA, Takeshi OGURA, Fumitaka OGUSHI, Masashi KAWANISHI, Waka ICHIKAWA, Kazuhito MIZUNO, Seiko ISHIKAWA, Yoshihiro TAKISHITA, Hiroyasu BANDO, Yoshihiro HASHIMOTO, Nobuhiro NARITA, Masayoshi SAWAKI, Keiichi MIKASA, Mitsuru KONISHI, Toshiharu MATSUSHIMA, Makoto KIMURA, Masayasu KAWANISHI, Tadasu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Takao SASAKI, Yukio MATSUMOTO, Yuji SUGIMOTO, Yoshiro SAWAE, Toshiyuki ISHIMARU, Koji TAKAGI, Nobuyuki SHIMONO, Nobuaki SHIGEMATSU, Katsuro YAGAWA, Shinichiro HAYASHI, Kenji KONO, Keisuke ONUKI, Shinichi TOHARA, Seiji TAKEDA, Masahide TAKII, Katsumi OKUDAIRA, Akihiko SAKAUE, Koichi SHINOHARA, Kotaro OIZUMI, Yoichiro ICHIKAWA, Masashi KAWAHARA, Kohei HARA, Masaki HIROTA, Keizo YAMAGUCHI, Shigeru KONO, Hironobu KOGA, Mitsuo KAKU, Yasumasa DOTSU, Hiroshi YAMADA, Kiyoyasu FUKUSHIMA, Naofumi SUYAMA, Toshiaki HAYASHI, Keizo MATSUMOTO, Toshiaki YOSHIDA, Tsuyoshi NAGATAKE, Moritoshi AKIYAMA, Masakazu TAKASUGI, Mikio TAGUCHI, Kiwao WATANABE, Harumi SHISHIDO, Kiyoshi SHIMA, Shinobu TAKENAKA, Masaru NASU, Jun GOTO, Hideaki SHIGENO, Yoichiro GOTO, Takayoshi TASHIRO, Hiroyuki NAGAI, Toru YAMAZAKI, Mitsunobu AKASHI, Hiroshi FUKUHARA, Hiroshi KANESHIMA, Yuei IRABU, Katsuyoshi SHIMOJI, Keizo KITSUKAWA, Yoshiteru SHIGENO, and Nobuya OGAWA

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, education, Ceftazidime, CEFPIROME SULFATE, medicine, Humans, In patient, Clinical efficacy, Intensive care medicine, Respiratory Tract Infections, Aged, Aged, 80 and over, Respiratory tract infections, business.industry, Significant difference, General Medicine, Cefpirome, Middle Aged, Cephalosporins, Clinical trial, Anesthesia, Female, business, medicine.drug
Abstract

Efficacy and safety of a new injectable cephem antibiotic, cefpirome sulfate (hereafter, CPR), against respiratory tract infections were examined and compared with those of a control drug, ceftazidime (hereafter, CAZ). As a rule, CPR 0.5 g twice a day, 1.0 g twice a day, or CAZ 1.0 g twice a day (hereafter CPR 0.5 g group, CPR 1.0 g group, and CAZ group) was administered for 14 days and the following results were obtained. 1. The total number of cases was 470 (155 cases in the CPR 0.5 g group, 160 cases in the CPR 1.0 g group, and 155 cases in the CAZ group). Among them 390 cases were subjected to analyses of clinical efficacy by the efficacy evaluation committee (131 cases in the CPR 0.5 g group, 131 cases in the CPR 1.0 g group and 128 cases in the CAZ group). 2. Efficacy rates determined by the efficacy evaluation committee were 82.4% (108/131) for the CPR 0.5 g group, 81.7% (107/131) for the CPR 1.0 g group, and 83.6% (107/128) for the CAZ group. Efficacy rates determined by the physician in charge were 82.0% (105/128) for the CPR 0.5 g group, 80.5% (99/123) for the CPR 1.0 g group, and 88.5% (108/122) for the CAZ group. No statistically significant difference was observed among the 3 groups. In evaluation of equivalency, clinical efficacy for the CPR 0.5 g group and the CPR 1.0 g group determined by the clinical efficacy evaluation committee was proved to be statistically equivalent to that for the CAZ group. 3. In patients with pneumonia, efficacy rates determined by the efficacy evaluation committee were 87.1% (61/70) for the CPR 0.5 g group, 80.7% (71/88) for the CPR 1.0 g group, and 78.9% (56/71) for the CAZ group. Efficacy rates determined by the physician in charge were 85.3% (58/68) for the CPR 0.5 g group, 80.7% (67/83) for the CPR 1.0 g group, and 86.2% (56/65) for the CAZ group and no statistically significant difference was observed among the 3 groups. In patients with chronic respiratory tract infection, efficacy rates determined by the efficacy evaluation committee were 77.0% (47/61) for the CPR 0.5 g group, 83.7% (36/43) for the CPR 1.0 g group, and 89.5% (51/57) for the CAZ group. Efficacy rates determined by the physician in charge were 78.3% (47/60) for the CPR 0.5 g group, 80.0% (32/40) for the CPR 1.0 g group, and 91.2% (52/57) for the CAZ group. No statistically significant difference was observed among the 3 groups.(ABSTRACT TRUNCATED AT 400 WORDS)

Published
1991

3. [An optimum dose-finding study of HR810 (CPR) in chronic respiratory tract infections]

Author

Rinzo SOEJIMA, Jiro HINO, Masaru SUMI, Niro OKIMOTO, Susumu YAGI, Kuninori TSUKIYAMA, Toshiharu MATSUSHIMA, Masayoshi KAWANISHI, Yohmei HIRAGA, Mitsuhide OHMICHI, Akira WATANABE, Kotaro OIZUMI, Yoshihiro HONDA, Yutaka TOKUE, Masakichi MOTOMIYA, Kazuo SATO, Kosaku NAGAI, Shigeru SHIMODA, Kiyoshi KONNO, Izumi HAYASHI, Hiroshi OSHITANI, Hiroshi MIURA, Takashi INOUE, Hiroyuki KOBAYASHI, Kaoru SHIMADA, Takashi INAMATSU, Mieko GOTO, Shinichi OKA, Hajime GOTO, Yoshitaka NAKAMORI, Koji NARUI, Masayuki NOGUCHI, Tatsuo NAKAYA, Koichiro NAKATA, Iwao SAKURAI, Takeo IMAI, Fumio MATSUMOTO, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MUROHASHI, Hiroshi TAKAHASHI, Yasuhiko ASHIKARI, Izumi KOYAMA, Toshikazu ISHII, Eiro TSUBURA, Masaru NAKAGAWA, Hideki NISHIKAWA, Yoshihiro TAKISHITA, Hiroyasu BANDO, Yoshihiro HASHIMOTO, Shinji ATAGI, Yukio MATSUMOTO, Mitsunobu YAMAMOTO, Tatsuya KONISHI, Yuji SUGIMOTO, Takuya SAKATA, Hiroaki HIRAI, Yutaka HITSUDA, Takao SASAKI, Kohei HARA, Masaki HIROTA, Shigeru KOHNO, Toshiaki HAYASHI, Naofumi SUYAMA, Yukishige MIYAZAKI, Yasumasa DOHTSU, Akira YASUOKA, Tatsuya KATSUMATA, Hiroshi YAMADA, Toshiaki YOSHIDA, Tsuyoshi NAGATAKE, Moritoshi AKIYAMA, Masakazu TAKASUGI, Mikio TAGUCHI, Kiwao WATANABE, Keizo MATSUMOTO, Masaru NASU, Jun GOTO, Hideaki SHIGENO, Yoichiro GOTO, Takayoshi TASHIRO, Hiroyuki NAGAI, Toru YAMAZAKI, Mitsunobu AKASHI, Atsushi SAITO, Hiroshi FUKUHARA, Hiroshi KANESHIMA, Yuei IRABU, Katsuyoshi SHIMOJI, Keizo KITSUKAWA, Yoshiteru SHIGENO, and Nobuya OGAWA

Subjects
Adult, Male, Adolescent, Ceftazidime, law.invention, Random Allocation, Randomized controlled trial, law, CEFPIROME SULFATE, medicine, Humans, Respiratory Tract Infections, Aged, Aged, 80 and over, Chi-Square Distribution, Respiratory tract infections, business.industry, Incidence (epidemiology), General Medicine, Middle Aged, Cephalosporins, Clinical trial, Diarrhea, Anesthesia, Chronic Disease, Drug Evaluation, Female, medicine.symptom, business, Chi-squared distribution, medicine.drug
Abstract

In order to determine the optimal dose of cefpirome sulfate (HR810, CPR) against respiratory tract infections (RTI), an optimal dose-finding study was conducted on cases of chronic RTI, and the clinical properties of the drug were compared with those of ceftazidime (CAZ). Inpatients with chronic RTI were randomly assigned to 3 groups: an HR 0.5 g group, receiving 0.5 g X 2/day of CPR an HR 1.0 g group, receiving 1.0 X 2/day of CPR and a CAZ group, receiving 1.0 g X 2/day of CAZ. As a rule, the drugs were administered by intravenous drip infusion for 14 days, after which period clinical efficacy, bacteriological response, safety, and utility were investigated. Of the total 121 cases, 106 were subject to analysis of clinical efficacy, including 38 cases in the HR 0.5 g group, 32 in the HR 1.0 g group, and 36 in the CAZ group. Efficacy rates in the assessment by the committee were 84.2% for the HR 0.5 g group, 75.0% for the HR 1.0 g group, and 86.1% for the CAZ group, without any significant difference between the 3 groups. The bacterial elimination rates were 73.9%, 75.0% m and 88.5%, respectively, without any significant difference between the 3 groups. Associated reactions were noted in 2 of 36 cases in the HR 1.0 g group (eruption and diarrhea), but not in the other 2 groups. The incidence of abnormal clinical laboratory findings was 23.1% in the HR 0.5 g group, 22.2% in the HR 1.0 g group, and 22.5% in the CAZ group, without any significant difference between the 3 groups. Utility rates were 84.2% for the HR 0.5 g group, 74.2% for the HR 1.0 g group, and 86.1% for the CAZ group, without any significant difference between the 3 groups. The HR 0.5 g and 1.0 groups showed no difference in clinical efficacy, bacteriological response, safety, and utility against RTI, and the results of both groups were about equal to those of the CAZ group.

Published
1991

4. Comparative Study on Sultamicillin and Bacampicillin in the Treatment of Respiratory Tract Infections

Author

Hiroyuki KOBAYASHI, Kenji TAKAMURA, Kota KONO, Tomoko NIHEI, Akira SAITO, Ichiro NAKAYAMA, Akira UJIIE, Osamu YAJIMA, Mikihiko TANGO, Masumi TOMIZAWA, Yoshio KURIHARA, Yomei HIRAGA, Kohki KIKUCHI, Asako YAMAMOTO, Masao TAMURA, Takashi ITO, Shinya MIYAMOTO, Kiyoshi KONNO, Kotaro OIZUMI, Seiichi AONUMA, Kosaku NAGAI, Izumi HAYASHI, Tsugushi ITO, Masataka KATSU, Kenichi OKAYAMA, Masaaki ARAKAWA, Hajime TAKEDA, Koichi WADA, Osamu SEKINE, Nobuki AOKI, Yoshimaru USUDA, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Yutaka KANAZAWA, Tadashi MIYAHARA, Atsushi SAITO, Kohya SHIBA, Hideo IKEMOTO, Kazuyoshi WATANABE, Kentaro WATANABE, Masaru KOYAMA, Katsuhito ITO, Fukuo IIJIMA, Keimei MASHIMO, Tetsuro UKAI, Hiroichi TANIMOTO, Tatsuo NAKATANI, Kunihiko YOSHIMURA, Yoshitaka NAKAMORI, Naohiko CHONABAYASHI, Koichiro NAKATA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Yasuyuki SANO, Ryozo YONEDA, Atsuyuki KURASHIMA, Ippei FUJIMORI, Yoshio KOBAYASHI, Yasushi NAKAMURA, Kazufuto FUKAYA, Tadashi TAKIGAMI, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MUROHASHI, Shinichiro WATANABE, Masanori MATSUMURA, Keinosuke NOSE, Kaoru OYAMA, Nobuo OHYA, Mitsuru HAYASE, Toshihiko TAKEUCHI, Toshiyuki YAMAMOTO, Masahito KATO, Joichi KATO, Hidekazu HANAKI, Ikuji USAMI, Fumiyuki KUZE, Michiyasu NAKANISHI, Hideki NISHIYAMA, Hiroyuki TSUJINO, Nobuo INABA, Akira KAGIOKA, Takekuni IWATA, Kazukiyo OIDA, Tsuneo MATSUBARA, Kohei AOKI, Hiroshi OKUBO, Yoshihiro UEDA, Keigo MAEHARA, Yube IIDA, Seibun YONEZU, Yuruko OKAMOTO, Kojiro YASUNAGA, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Minoru YOSHIYAMA, Susumu HIRAGA, Tetsuto MURATA, Shinichi TANIZAWA, Kazuo SAKAMOTO, Kazunori KOZUMI, Kenji TAKAMATSU, Riichiro MIKAMI, Masayoshi SAWAKI, Rinzo SOEJIMA, Yoshihito NIKI, Masatoshi WATANABE, Osamu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Masakazu TAMURA, Yoshiro SAWAE, Kaoru OKADA, Minoru YOSHIDA, Masahide TAKII, Masahiko SEKI, Hitoshi NAGANO, Ryuji HIROSE, Atsushi SHINODA, Tsuneo ISHIBASHI, Masahiro TAKAMOTO, Kohei HARA, Kinichi IZUMIKAWA, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Akira IKEBE, Toshiro ODA, Michisuke OHTA, Keizo MATSUMOTO, Mikio TAGUCHI, Tsuyoshi NAGATAKE, Takashi ITOGA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Takayoshi TASHIRO, Yasuyuki HAYASHI, and Toyoko OGURI

Subjects
Adult, Male, medicine.medical_specialty, Penicillin Resistance, Sultamicillin, Penicillanic Acid, Gastroenterology, Double-Blind Method, Ampicillin, Internal medicine, medicine, Humans, Respiratory Tract Infections, Aged, Clinical Trials as Topic, Respiratory tract infections, business.industry, Pneumonia, General Medicine, Sulbactam, Middle Aged, medicine.disease, Drug Combinations, Penicillin resistance, Bacampicillin, Drug Evaluation, Female, business, medicine.drug
Published
1985

5. Comparative Study of Cefuzonam (CZON) with Cefotiam in Bacterial Pneumonia and Pulmonary Suppuration

Author

Rinzo SOEJIMA, Toshiharu MATSUSHIMA, Yoshihito NIKI, Hiroshi KAWANE, Masayasu KAWANISHI, Masatoshi WATANABE, Jiro HINO, Yoshihisa NAKAGAWA, Shigenobu UMEKI, Masaru SUMI, Toshio KISHIMOTO, Akira SAITO, Ichiro NAKAYAMA, Masumi TOMIZAWA, Shinya YASUDA, Tetsuji KORAKU, Hiromichi HORIKAWA, Akio HIRAYAMA, Soichiro UEHARA, Masashi TAMURA, Takashi ITO, Fumitoshi YAMAUCHI, Hitoshi KOBAYASHI, Kazumichi MIYA, Yoshikatsu NEMOTO, Tamotsu TAKISHIMA, Shiro IDA, Makoto TAKAHASHI, Tadao ISE, Kiyoshi KONNO, Kotaro OIZUMI, Akira WATANABE, Kikuo ONUMA, Yuji NAKAI, Kosaku NAGAI, Kenji BABA, Masayuki ITO, Fumio ARIJI, Teruo HASUIKE, Yoichi FUKUDA, Izumi HAYASHI, Tsuguji ITO, Masaaki ARAKAWA, Koichi WADA, Masanaga TAKATO, Morito IWANAGA, Fusanosuke YAMASAKU, Yasutoshi SUZUKI, Osamu SEKINE, Nobuki AOKI, Masataka KATSU, Shinji OKUI, Takashi YOKOSE, Yasushi UEDA, Tadashi MIYAHARA, Atsushi SAITO, Hideo IKEMOTO, Kazuyoshi WATANABE, Hiroyuki KOBAYASHI, Kota KONO, Hiroaki TAKEDA, Keimei MASHIMO, Tadahiro KURASAWA, Hiroichi TANIMOTO, Naohiko CHONABAYASHI, Kunihiko YOSHIMURA, Tatsuo NAKATANI, Koichiro NAKATA, Yoshitaka NAKAMORI, Hiroko SUGI, Junzaburo KABE, Yasuyuki SANO, Koichiro KUDO, Tetsuzo WATANABE, Mitsuo YAMAGISHI, Fuyuhiko HIGASHI, Yuzo FUNATSU, Takashi INAMATSU, Shinichi OKA, Akio AOYAGI, Ippei FUJIMORI, Yoshio KOBAYASHI, Mitsuo OBANA, Takao OKUBO, Akira ITO, Shigeki ODAGIRI, Hideo TAKAHASHI, Tomiji MIURA, Kaitaro YAMABE, Makio KURIHARA, Kenichi TAKAHASHI, Fumio MATSUMOTO, Tatsuo SATAKE, Kenzo TAKAGI, Kenichi YAMAKI, Ryujiro SUZUKI, Shigeki YOKOYAMA, Hitoshi IWATA, Motohide SASAMOTO, Tomoyasu SASAKI, Masatoshi IMAI, Masao TANO, Masahito KATO, Toshihiko TAKEUCHI, Teiichi KATO, Yoshimitsu HAYASHI, Hidekazu HANAKI, Yoji USAMI, Hideaki KUROKI, Fumiyuki KUZE, Takako MURAYAMA, Hideki NISHIYAMA, Motokazu KATO, Hiroshi OKUBO, Yoshihiro UEDA, Tadanao TAKEDA, Naotsugu KURIHARA, Kazuhiko TERAKAWA, Yuriko OKAMOTO, Seibun YONEZU, Yube IIDA, Yoshihiko SAKAKIBARA, Kojiro YASUNAGA, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Akihito MURATA, Shinichi TANIZAWA, Kazuo SAKAMOTO, Hirozumi SAKAI, Kenzo SHIODA, Keiji KOBAYASHI, Yoshio YAMADA, Kiyomichi YOSHIMARU, Eiro TSUBURA, Koichi FUKUYAMA, Masaru NAKAGAWA, Eiji CHIKATA, Yasuhiro HASEGAWA, Einosuke UEDA, Hideki NISHIKAWA, Yukio NISHIMOTO, Michiro YAMAKIDO, Akimitsu KAMITSUNA, Yoshinao IHARA, Kazuo ITASAKA, Osamu KURIMURA, Hirofumi FUKUHARA, Hideo SASAKI, Masakazu TAMURA, Yoshiro SAWAE, Yukio KUMAGAI, Jun NAGANO, Hiroshi NAKANO, Chiharu KUBO, Hiroko KAWAMURA, Atsushi SHINODA, Masahiro TAKAMOTO, Tsuneo ISHIBASHI, Masashi KAWAHARA, Yasuko HARADA, Kohei HARA, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Takakazu KIYA, Kyoko YAMASHITA, Kazuo SASAYAMA, Toshiaki HAYASHI, Hiroshi TOMITA, Kinichi IZUMIKAWA, Kazunori SHIMOGUCHI, Tsunetoshi KOTEDA, Koichi WATANABE, Kazuhiro OKUNO, Keizo MATSUMOTO, Fumishige SONODA, Toshiaki YOSHIDA, Akira SAKAMOTO, Masaru NASU, Yoichiro GOTO, Jun GOTO, Takayoshi TASHIRO, Yasuko OJIRO, Minoru NISHIMIYA, Toshinori KAWASAKI, Syukuro ARAKI, Masayuki ANDO, Moritaka SUGA, Toshifumi NIIBORI, Hidetsugu KAMIYAMA, Kazuko YOSHIDA, Fujio TANAKA, Kazumine KOBORI, and Masao NAKATOMI

Subjects
Adult, Aged, 80 and over, Lung Diseases, Male, Suppuration, Cefotiam, business.industry, Ceftizoxime, Bacterial pneumonia, Bacterial Infections, Cefotaxime, Pneumonia, General Medicine, Middle Aged, medicine.disease, Cefuzonam, Cephalosporins, Microbiology, Humans, Medicine, Female, business, Aged, medicine.drug
Published
1986

6. [Comparative study of TMS-19-Q and midecamycin for respiratory tract infection by double-blind method]

Author

Hiroyuki KOBAYASHI, Tomoko NIHEI, Hiroaki TAKEDA, Kohta KOHNO, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Yomei HIRAGA, Kohki KIKUCHI, Asako YAMAMOTO, Kazuo TAKEBE, Shiro KOSAKA, Teruo NAKAMURA, Shuichiro YOSHIDA, Masao TAMURA, Takashi ITO, Taro CHIBA, Ryoji OGATA, Kazuo TANIFUJI, Kotaro ITAKURA, Kiyoshi KONNO, Kotaro OIZUMI, Kosaku NAGAI, Izumi HAYASHI, Tatsuya ABE, Masataka KATSU, Shinji OKUI, Masanori ADACHI, Atsushi SAITO, Kohya SHIBA, Tadashi MIYAHARA, Tetsuro UGAI, Yoshiji YAMANE, Keimei MASHIMO, Keiichi NAKAGAWA, Masaru KOYAMA, Ryuji AKIYOSHI, Ichiro MURATA, Ippei FUJIMORI, Yoshio KOBAYASHI, Mitsuo OBANA, Fumio MATSUMOTO, Shigeki ODAGIRI, Hirotada IKEDA, Kaneo SUZUKI, Kou MUROHASHI, Tamotsu KANEKO, Osamu SEKINE, Yoshimaru USUDA, Nobuki AOKI, Fusanosuke YAMASAKU, Kaoru OYAMA, Toshiyuki YAMAMOTO, Masahito KATO, Kunio NANJO, Motoko YAMAMOTO, Hidekazu HANAKI, Hirohiko NAGASAKA, Tsuyoshi ITO, Toshihiko TAKEUCHI, Masakazu KOHNO, Fumio MIKI, Kenji TAKAMATSU, Yuruko OKAMOTO, Keigo MAEHARA, Yube IIDA, Rinzo SOEJIMA, Toshiharu MATSUSHIMA, Yoshihito NIKI, Hiroshi KAWANE, Masayoshi KAWANISHI, Chikara NAKAHAMA, Masatoshi WATANABE, Jiro HINO, Michio YAMAKIDO, Yuzo ODA, Osamu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Masakazu TAMURA, Toshihiro GOTO, Eiro TSUBURA, Yoshiro SAWAE, Kaoru OKADA, Yukio KUMAGAI, Kohei HARA, Kinichi IZUMIKAWA, Keizo YAMAGUCHI, Yoji SUZUYAMA, Yoshiteru SHIGENO, Munetaka KOMORI, Naomi ITO, Masao SAI, Hiromaru IWASAKI, Koichi WATANABE, Akira IKEBE, Kozo YAMADA, Keizo MATSUMOTO, Yoshio UZUKA, Masayuki ANDO, Mineharu SUGIMOTO, Moritaka SUGA, Shukuro ARAKI, Yasutsugu FUKUDA, Katsumasa TOKUNAGA, Haruhiko TOKUOMI, Takashi ITOGA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Takayoshi TASHIRO, Kazumine KOBARI, Yuei IRABU, Yutoku KINJO, Masao NAKATOMI, and Tsuneo TANAKA

Subjects
medicine.medical_specialty, Clinical Trials as Topic, business.industry, General Medicine, Bacterial Infections, Pneumonia, Gastroenterology, Leucomycins, Midecamycin, Double blind, medicine.anatomical_structure, Double-Blind Method, Internal medicine, Pneumonia, Mycoplasma, Medicine, Humans, Miocamycin, business, medicine.drug, Respiratory tract
Published
1985

7. [Comparative clinical trial of HBK and amikacin (AMK) in the treatment of respiratory infections]

Author

Kohei HARA, Atsushi SAITO, Keizo YAMAGUCHI, Yoshiteru SHIGENO, Kazushige TAIRA, Toshiro ODA, Toshiaki HAYASHI, Hiroshi TOMITA, Yasuharu MASUYAMA, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Morikuni ABE, Shosei MATSUHASHI, Kiyofumi ISHIKAWA, Akira UJIIE, Takehito NAKABAYASHI, Tetsuji KOROKU, Yohmei HIRAGA, Kohki KIKUCHI, Asako YAMAMOTO, Kazuo TAKEBE, Katsuhiro OKAMOTO, Morio SAGARA, Toyokazu TAMURA, Katsumi ENDO, Tatsuro IRIE, Osamu UEHARA, Masao TAMURA, Takashi ITO, Kazuo OBARA, Shinya MIYAMOTO, Tomohiro KANAZAWA, Hiroshi TAKAHASHI, Hirokazu KUROKAWA, Shoji YASUI, Keiji TAKAHASHI, Shinobu SATO, Hideki IKEDA, Hidenori NAKAMURA, Seiji YASUMURA, Kohichi IGARASHI, Hikaru HOSHI, Sunao YAKUWA, Tamotsu TAKISHIMA, Shiroh IDA, Kiyoshi KONNO, Kotaro OIZUMI, Seiichi AONUMA, Akira WATANABE, Kosaku NAGAI, Kazuo SATO, Izumi HAYASHI, Masataka KATSU, Mieko KAWAI, Koji OGIWARA, Takeshi KAWAI, Atsushi AJISAWA, Shigeaki SATO, Kazuhito ISHIKAWA, Tadashi MIYAHARA, Hideo IKEMOTO, Kazuyoshi WATANABE, Hiroshi ISONUMA, Hiroyuki KOBAYASHI, Shin KAWAI, Masahiko YOSHIDA, Otohiko KUNII, Keimei MASHIMO, Yoshiji YAMANE, Tetsuro UKAI, Masaru KOYAMA, Fukuo IIJIMA, Junzaburo KABE, Hiroyoshi ISHIBASHI, Yuko UNO, Hiroichi TANIMOTO, Naohiko CHONABAYASHI, Yoshitaka NAKAMORI, Kunihiko YOSHIMURA, Tatsuo NAKATANI, Koichiro NAKATA, Gohta MASUDA, Masayoshi NEGISHI, Chenden YOUNG, Fuyuhiko HIGASHI, Yuzo FUNATSU, Ippei FUJIMORI, Yoshio KOBAYASHI, Takao OKUBO, Akira ITO, Fumihiko SANO, Michio MATSUZAKI, Yuko ASADA, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MUROHASHI, Tsutomu FUKUDA, Yasuhiro YOSHIIKE, Masanori MATSUMURA, Mitsuyo KIUCHI, Fumio MATSUMOTO, Kazufuto FUKAYA, Tadashi TAKIGAMI, Masataka SHODA, Masaaki ARAKAWA, Kohichi WADA, Osamu SEKINE, Nobuki AOKI, Kaoru OYAMA, Shinobu NAKAMURA, Takeshi NAKAMURA, Toshiyuki YAMAMOTO, Kanzo SUZUKI, Akira ADACHI, Fumiyuki KUZE, Michiyasu NAKANISHI, Takuya KURASAWA, Yoshiro KUBO, Hideki NISHIYAMA, Nobuaki IKEDA, Norio INABA, Akira KAGIOKA, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Akihito MURATA, Shin-ichi TANIZAWA, Kazuo SAKAMOTO, Kenji TAKAMATSU, Rinzo SOEJIMA, Yoshihito NIKI, Jiro HINO, Yoshihisa NAKAGAWA, Yukio NISHIMOTO, Michio YAMAKIDO, Akimitsu KAMITSUNA, Kenji HASEGAWA, Osamu KURIMURA, Hideo SASAKI, Hirofumi FUKUHARA, Masakazu TAMURA, Eiro TSUBURA, Koichi FUKUYAMA, Tadaaki MORIMOTO, Yoshiro SAWAE, Hitoshi NAGANO, Takeo YOKOTA, Kinji YOKOTA, Atsushi SHINODA, Tsuneo ISHIBASHI, Masahiro TAKAMOTO, Yasuko HARADA, Yoshinari KITAHARA, Masaro KAJI, Yoichiro ICHIKAWA, Masaru NASU, Jun GOTO, Yoichiro GOTO, Hitoshi YAMAZAKI, Takayoshi TASHIRO, Keizo MATSUMOTO, Kazunori OHISHI, Kinichi IZUMIKAWA, Tsunetoshi KOTEDA, Manabu NAKAJIMA, Kohei KOMATSU, Masaya NAKATA, Reiko SENJU, Masayuki ANDO, Moritaka SUGA, Toshifumi NIIBORI, Toshiyuki NAKAGAWA, Kazuko YOSHIDA, Kazumine KOBARI, Masao NAKATOMI, and Tsuneo TANAKA

Subjects
Adult, Male, medicine.medical_specialty, Double-Blind Method, Kanamycin, medicine, Humans, Respiratory system, Intensive care medicine, Amikacin, Respiratory Tract Infections, Aged, Aged, 80 and over, Clinical Trials as Topic, business.industry, Dibekacin, General Medicine, Bacterial Infections, Middle Aged, Anti-Bacterial Agents, Clinical trial, Aminoglycosides, Female, business, medicine.drug
Published
1987

8. [Comparative clinical study of CS-807 and cefaclor for bacterial pneumonia by a double-blind method]

Author

Khoya SHIBA, Atsushi SAITO, Jingoro SHIMADA, Tadashi MIYAHARA, Soukichi ONODERA, Nobuhiro SASAKI, Akira SAITO, Masumi TOMIZAWA, Ichiro NAKAYAMA, Masao TAMURA, Takashi ITO, Mamoru MICHIMATA, Katsuyoshi MORIYA, Kotaro ITAKURA, Kazumichi MIYA, Tamotsu TAKISHIMA, Shiroh IDA, Yoshio TANNO, Kiyoshi KONNO, Kotaro OIZUMI, Akira WATANABE, Seiichi AONUMA, Kosaku NAGAI, Izumi HAYASHI, Tsugushi ITO, Shizuo HASEGAWA, Yasuyuki YOSHIZAWA, Yoshiyuki UCHIDA, Masataka KATSU, Tsuguji OKUI, Toshio FUKUI, Mieko KAWAI, Toshihito TOGO, Kazuo MIZUKOSHI, Takeo TOYODA, Tohru ABE, Jun KOIDE, Fuyuhiko HIGASHI, Yuzo FUNATSU, Takashi INAMATSU, Makiko FUKAYAMA, Junzaburou KABE, Hiroyoshi ISHIBASHI, Kouichirou KUDOU, Hideo IKEMOTO, Kazuyoshi WATANABE, Hiroichi TANIMOTO, Yoshitaka NAKAMORI, Kunihiko YOSHIMURA, Tatsuo NAKATANI, Naohiko CHONABAYASHI, Koichiro NAKATA, Keimei MASHIMO, Yoshiji YAMANE, Tatsuo KATO, Toshiichi HARADA, Kaoru SHIMADA, Hajime ORIMO, Yoshinosuke FUKUCHI, Makoto YAMAOKA, Kentaro WATANABE, Masaru KOYAMA, Hiroyuki KOBAYASHI, Hiroaki TAKEDA, Masashi INOUE, Hiroshi MIURA, Yuichiro UEDA, Hajime NISHIYA, Yasuo ONO, Norio NOZUE, Hajime MURAOKA, Toshiaki HAGA, Otohiko KUNII, Hideo MIYASHITA, Ippei FUJIMORI, Yoshio KOBAYASHI, Tomohiro FURUKAWA, Yasuhisa KITAGAWA, Kazufuto FUKAYA, Akira ITO, Takao OKUBO, Shigeki ODAGIRI, Kaneo SUZUKI, Kou MOROHASHI, Masaaki ARAKAWA, Koichi WADA, Osamu SEKINE, Nobuki AOKI, Hajime TAKEDA, Kaoru OYAMA, Kaoru SHIMOKATA, Yoshihiro SENDA, Shuzo SAKAI, Osamu KOUNOU, Keisuke NISHIWAKI, Toshihiko TAKEUCHI, Masahito KATO, Hidekazu HANAKI, Sakae KAN, Kunio NANJO, Toshiyuki YAMAMOTO, Kanzo SUZUKI, Kazuhide YAMAMOTO, Satoru ADACHI, Fumiyuki KUZE, Mitsuru KAWAI, Fumio MIKI, Yoshiyasu IKUNO, Eiji INOUE, Akihito MURATA, Shinichi TANIZAWA, Kazuo SAKAMOTO, Akira TAHARA, Yoshio KAWASE, Kojiro YASUNAGA, Seibun YONEZU, Yube IIDA, Yoshihiko SAKAKIBARA, Yoshihiro UEDA, Hiroshi OKUBO, Kenzo SHIOTA, Keiji KOBAYASHI, Rinzo SOEJIMA, Yoshihito NIKI, Takeshi OGURA, Susumu YASUOKA, Toshio OZAKI, Yoshiro SAWAE, Atushi SHINODA, Tsuneo ISHIBASHI, Masahiro TAKAMOTO, Yasuko HARADA, Yoshiya KITAHARA, Hideaki NINOMIYA, Kohei HARA, Masaki HIROTA, Keizo YAMAGUCHI, Shigeru KOHNO, Toshiaki HAYASHI, Yasumasa DOTSU, Taiji MASUYAMA, Yuuichi INOUE, Yoshihiro OHTA, Toshiro ODA, Touru ISHINO, Koichi WATANABE, Akitoshi KINOSHITA, Keizo MATSUMOTO, Atsushi TAKAHASHI, Masaru NASU, Takayoshi TASHIRO, Jun GOTO, Hideaki SHIGENO, and Yoichiro GOTO

Subjects
Adult, Male, medicine.medical_specialty, Adolescent, Chemical Phenomena, Double blind, Clinical study, Double-Blind Method, Internal medicine, medicine, Humans, Multicenter Studies as Topic, Cefaclor, Aged, Cephalexin, Clinical Trials as Topic, business.industry, Bacterial pneumonia, Ceftizoxime, General Medicine, Bacterial Infections, Pneumonia, Middle Aged, medicine.disease, Cephalosporins, Chemistry, Female, business, medicine.drug
Published
1988

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