1. Extensively drug-resistant Salmonella Typhi in a patient returning from Pakistan, complicated by relapse with meropenem monotherapy
- Author
-
Abhimanyu Kaura, Maria A. Caravedo, and David Reynoso
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Abdominal pain ,030106 microbiology ,Drug resistance ,Infectious and parasitic diseases ,RC109-216 ,Salmonella typhi ,Meropenem ,complex mixtures ,Typhoid fever ,Article ,Third generation cephalosporins ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Extremely drug resistant salmonella(XDR salmonella) ,030212 general & internal medicine ,Relapse ,Travel ,business.industry ,Febrile illness ,medicine.disease ,bacterial infections and mycoses ,Infectious Diseases ,Salmonella enterica serovar Typhi ,medicine.symptom ,business ,medicine.drug - Abstract
In developing countries, typhoid fever is a common cause of febrile illness accompanied by abdominal pain and weakness. It is caused by Salmonella enterica serovar Typhi. Humans are the only known reservoir of infection, and typhoid fever is common in regions where access to clean water and sanitation is limited. The antimicrobials of choice for a case of typhoid fever acquired outside Pakistan are third generation cephalosporins. Lately, cases of extensively drug-resistant (XDR) Salmonella Typhi have been reported in people with a travel history to Pakistan. We present a case of XDR typhoid fever which relapsed after treatment with meropenem.
- Published
- 2021