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Aim: The purpose of this work was to study the dynamics of structural manifestations of acute cases of postpartum endometritis in cows. Materials and Methods: The light and electron microscopy methods were used when studying structural changes in the endometrium in case of postpartum endometritis in seven cows. Sections of endometrial specimens for light microscopy, 5-7 μm thick, were stained with hematoxylin and eosin and also by Van Gieson's. For electron microscopy, semi-thin sections were stained with Azur-2 in combination with basic fuchsin, as well as contrasting by lead citrate and uranyl acetate. Results: As a result of the study, we have established the following: Necrobiosis of the epithelial layer of the mucosa, cellular infiltration with shaped elements of blood in the functional layer, swelling of the cells of the uterine gland, and single microbial cells on the surface of the mucosa. We have noted edema of the stroma of the functional layer of the endometrium, swelling of the epithelial layer of the endometrial mucosa, and swelling of fibroblastic and lymphoid cells. Ultrastructural changes in endometrial cells in case of acute postpartum endometritis in cows are accompanied by the destruction of microvilli on the apical surface of the epithelium, an abundance of coccal microflora on the surface of the epithelium, necrobiosis of epithelial cells, and partial edema of the nucleus, and cytoplasm of the histiocyte. Conclusion: We had established that acute purulent-catarrhal dystrophic processes were observed in the structural organization of the endometrium. In the depth of catarrhal mucus on the surface of the endometrium, there was an abundance of bacterial flora, with diplococci being prevalent. In ultrastructural organization of the endometrium, we observed deep dystrophic and necrobiotic processes in the parenchyma and endometrial stroma, as well as exudative processes with a change in the integrity of the microcirculatory bed. Thus, to prevent an inflammatory process from turning into a latent form, it is necessary to detect acute postpartum endometritis promptly using diagnostic methods taking into account the obtained parameters of the dynamics of structural changes in the uterine tissues.

There is no objection that many pathological manifestations after thrombosis of cerebral vessels are associated in many respects with microcirculation disorders. These dysfunctions of microcirculation on the side of the lesion in patients are increasingly considered a point of influence for the recovery of this contingent of patients. In this connection, it is required to clarify the state of microcirculation in post-stroke patients at the late stage of their rehabilitation. In the article, the state of microcirculation in patients was clarified 7 months after the stroke. It was found that the deterioration of microcirculation processes is very typical for this contingent of patients, especially on the paretic side. Apparently, improvement in the state of motor function in patients after thrombosis of cerebral vessels is associated with increased microcirculation in affected limbs and in healthy limbs. The disturbances of microcirculation persisting in patients give grounds to recommend such a combination of drug treatment and nonmedicamentous effects in the late stages of recovery, using the latter particularly actively on the affected side.

Shar-Pei's amyloidosis is a hereditary disease which is characterized by amyloid deposition in stromal-vascular organs. The contributory cause of amyloidosis is а genetic disease Shar Pei's fever. Amyloidosis is based on enzymatic processes abnormality in connective-tissue cells. Enzymopathy is followed by synthesis of the abnormal fibrous protein entering strong compound with proteins of plasma and glycosaminoglycans of ground substance of connective tissue.