1. Morbihan Syndrome, a UK Case Series
- Author
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Hardeep Singh Mudhar, Camille Yvon, Raman Malhotra, Tessa Fayers, Jennifer H Y Tan, Saul N. Rajak, We Fong Siah, and Zanna I. Currie
- Subjects
Male ,medicine.medical_specialty ,Chronic condition ,Triamcinolone acetonide ,Erythema ,Disease ,03 medical and health sciences ,0302 clinical medicine ,Edema ,Biopsy ,medicine ,Humans ,Isotretinoin ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Debulking ,Dermatology ,United Kingdom ,Ophthalmology ,Rosacea ,030221 ophthalmology & optometry ,Surgery ,medicine.symptom ,business ,medicine.drug - Abstract
Purpose To describe 10 patients with Morbihan syndrome, a rare condition characterized by the slow appearance of erythema and solid edema on the upper portion of the face, and review the literature. Methods Retrospective case series and review. Results The majority of patients were male (80%), and the mean age at presentation was 67 years (range, 48-88 years); 60% had asymmetrical disease (affecting mainly the right side). All subjects underwent a lid biopsy to support the diagnosis of Morbihan syndrome, which showed features of inflammation and vascular dysfunction, highly suggestive of a rosacea histological picture complicated by chronic lymphoedema. A range of medical and surgical treatment were used with variable success. The most effective ones included oral isotretinoin, intralesional triamcinolone injections, and debulking surgery. Conclusions Morbihan syndrome is a rare and chronic condition. It can be difficult to treat and may require a range of interventions.
- Published
- 2020
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