1. Association of Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorders with Mean Platelet Volume and Vitamin D
- Author
-
Tuba Mutluer, Sultan Kaba, Murat Doğan, Lokman Üstyol, Mesut Garipardic, Keziban Aslı Bala, and Oktay Aslan
- Subjects
Male ,Vitamin ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Autism Spectrum Disorder ,Disease ,030204 cardiovascular system & hematology ,behavioral disciplines and activities ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Clinical Research ,Risk Factors ,mental disorders ,Vitamin D and neurology ,Humans ,Medicine ,Attention deficit hyperactivity disorder ,Vitamin B12 ,Autistic Disorder ,Vitamin D ,Mean platelet volume ,Child ,business.industry ,Vitamin B 12 Deficiency ,Avitaminosis ,Adhd group ,General Medicine ,medicine.disease ,Vitamin B 12 ,chemistry ,Attention Deficit Disorder with Hyperactivity ,Cardiovascular Diseases ,Autism ,Female ,business ,Mean Platelet Volume ,Biomarkers ,030217 neurology & neurosurgery - Abstract
BACKGROUND The purpose of this study was to assess the values of the mean platelet volume (MPV) in children with attention deficit hyperactivity disorder (ADHD) and with autism spectrum disorders (ASDs) to determine the risk of cardiovascular disease in these 2 disorder groups. MATERIAL AND METHODS The study included a total of 79 patients with ADHD or ASDs and controls in the Van region of Turkey. The control group included subjects of matching age and sex with no ADHD, ASDs, or chronic disease and taking no vitamins. The hematological parameters of the patients, including MPV, vitamin B12, and vitamin D, were assessed. RESULTS The study included a total of 79 children and adolescents aged 2-18 years (32 females and 47 males). Of the patients, 36 were in the ADHD group, 18 in the ASDs group, and 25 in the control group. There was no statistically significant difference in hematological parameters between the groups, but there were significant differences in terms of vitamin D and vitamin B12. The patient groups showed lower levels of vitamin B12 and vitamin D. In the ADHD group, there was a negative correlation between both vitamins and MPV (p
- Published
- 2017