1. Correlation between severity of spinal stenosis and multifidus atrophy in degenerative lumbar spinal stenosis
- Author
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Bin Fu, Gen Xia, Yongdong Qiao, Xueru Li, Yanbing Shang, Feng Jiang, and Huan Liu
- Subjects
Male ,medicine.medical_specialty ,Spinal stenosis ,Paraspinal Muscles ,Diseases of the musculoskeletal system ,Claudication distance ,Multifidus muscle ,Multifidus atrophy ,03 medical and health sciences ,Spinal Stenosis ,0302 clinical medicine ,Atrophy ,Rheumatology ,medicine ,Humans ,Orthopedics and Sports Medicine ,Spinal canal ,030212 general & internal medicine ,Spinal stenosis TCSA/TFCSA ratio ,Aged ,Retrospective Studies ,Lumbar Vertebrae ,business.industry ,Research ,Muscle weakness ,medicine.disease ,Magnetic Resonance Imaging ,Muscle atrophy ,Muscular Atrophy ,Stenosis ,medicine.anatomical_structure ,RC925-935 ,Orthopedic surgery ,Female ,Radiology ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Degenerative lumbar spinal stenosis - Abstract
Background Degenerative lumbar spinal stenosis (DLSS) is a common degenerative condition in older adults. Muscle atrophy (MA) is a leading cause of muscle weakness and disability commonly reported in individuals with spinal stenosis. The purpose of this study was to investigate if the MA correlates with the grade of spinal stenosis in patients with DLSS. Methods A retrospective analysis on 48 male and 184 female DLSS patients aged around 54.04 years (54.04 ± 8.93) were involved and divided into 6 groups according to claudication-distance-based grading of spinal stenosis, which confirmed by two independent orthopedic surgeons using T2- weighted images. Using 1.5T MRI scanner, the severity of MA is assessed based on its negative correlation with the ratio of total fat-free multifidus muscle cross-sectional area (TFCSA) to total multifidus muscle cross-sectional area (TCSA). Adobe Photoshop CS6 was used for qualitative image analysis and calculate the TFCSA/TCSA ratio to assess the severity of MA, compare the grade of MA with the spinal stenosis segment, stenosis grade and symptom side. Results In DLSS group, The TFCSA/TCSA ratio are 74.33 ± 2.18 in L3/4 stenosis, 75.51 ± 2.79 in L4/5 stenosis, and 75.49 ± 2.69 in L5/S1 stenosis. there were significant decreases in the TFCSA/TCSA ratio of stenotic segments compared with non-stenotic segments of the spinal canal (P < 0.05) while no significant difference between the non-stenotic segments (P > 0.05). TFCSA/TCSA ratios is significant differences in the TFCSA/TCSA ratios of the 6 DLSS groups (F = 67.832; P < 0.05). From Group 1 to Group 6, the TFCSA/TCSA ratio of stenotic segments positively correlated with the absolute claudication distance (ACD). (P r = 0.852). Besides, the TFCSA/TCSA ratios are smaller in the symptomatic sides of the spine than the contralateral sides (t = 4.128, P = 0.001). Conclusions The stenotic segments of the spinal canal are more atrophied than the non-stenotic segment in DLSS patients. It is shows that a strong positive correlation between the severity of multifidus atrophy and the severity of spinal stenosis.
- Published
- 2021