1. Effects of stimulant treatment on sleep in attention deficit hyperactivity disorder (ADHD)
- Author
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Miriam Sanabra, José A. Alda, Carlota Alcover, Oscar Sans, and Tary Gómez-Hinojosa
- Subjects
Pediatrics ,medicine.medical_specialty ,Neurology ,Physiology ,Methylphenidate ,business.industry ,medicine.medical_treatment ,Case-control study ,Actigraphy ,medicine.disease ,Sleep in non-human animals ,Stimulant ,03 medical and health sciences ,0302 clinical medicine ,Neuropsychology and Physiological Psychology ,Physiology (medical) ,mental disorders ,medicine ,Attention deficit hyperactivity disorder ,Sleep diary ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
The main objective of this study is to assess the prevalence of sleep disorders in treatment-naive children and adolescents with ADHD compared with healthy controls matched for age and gender; and, at the same time, to determine whether stimulant medication (methylphenidate) affects sleep in the same group of children and adolescents with ADHD (naive) after a 3-month treatment. A total of 120 children and adolescents (60 newly diagnosed with ADHD according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM IV), and 60 gender- and age-matched controls) were evaluated through objective (actigraphy) and subjective (sleep diary) measures. Later, of those 60 newly diagnosed with ADHD, 30 started pharmacological treatment with methylphenidate with a mean daily dose of 0.58 mg/kg. No significant differences in both measures within the ADHD group after following the 3-month pharmacological treatment with methylphenidate were found. There were neither any significant differences in sleep parameters through objective measures between the medication-naive ADHD group and the control group, while significant differences were found through sleep diary (registered by parents) in latency and efficiency (p =
- Published
- 2020
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