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Aim: In this study, sensitivity and specificity of the albumin-bilirubin (ALBI) score were investigated to detect significant liver fibrosis, and these findings were then compared to fibrosis-4 (FIB-4) and aspartate aminotransferase to platelet ratio index (APRI) scores. Material and Methods: A total of 69 patients were included in the study. Of these patients, 54 (78.3%) were male and 15 (21.7%) were female. Serology, molecular analysis, biochemical parameters, and pathology results of the patients who underwent a liver biopsy due to a chronic hepatitis B virus (HBV) infection, were retrospectively evaluated. ALBI, APRI, and FIB-4 scores were calculated. To predict the fibrosis stage, F≥2 and F≥4, ALBI, APRI, and FIB-4 scores were investigated using the receiver operator characteristic (ROC) curve analysis. Results: The area under the ROC curve with 95% confidence interval (CI) for the ALBI, APRI, and FIB-4 scores were 0.613 (95% CI: 0.463-0.762, p=0.160), 0.658 (95% CI: 0.513-0.803, p=0.040), and 0.731 (95% CI: 0.570-0.891, p=0.004), respectively, to predict the F≥2, and 0.758 (95% CI: 0.544-0.971, p=0.090), 0.604 (95% CI:0.451-0.757, p=0.490), and 0.923 (95% CI: 0.856-0.990, p=0.005), respectively, in prediction of F≥4. The sensitivity and specificity rates of the ALBI score were 61.1% and 64.7%, respectively, for the cut-off value of -2.81 in predicting F≥2, and 75.0% and 70.8% for the cut-off value of -2.78 in predicting F≥4. Conclusion: ALBI scores can be used to detect F≥2 in patients with chronic HBV. However, it is not yet clear whether this approach is superior to other non-invasive methods for detecting F≥4.

Angiomyofibroblastoma (AMFB) is a rare seen mesenchymal tumor that is categorized as a genital stromal tumor. It is commonly seen in the middle-aged women usually affecting the labia majora and rarely the vagina. A variant called AMFB-like tumors are also rarely seen in male patients. AMFB with its clinical presentation and location can be wrongly diagnosed as an aggressive angiomyxomas, bartholin cyst or lower genital tract lipomas. In the patients who are applying because of the vulvar mass, AMFB should not be forgotten for the pre-diagnosis. The treatment is generally simple surgical excision.In this case, AMFB was reported with a wrongly pre-diagnosis as a bartholin cyst to which a medical treatment had been given. [Cukurova Med J 2015; 40(4.000): 822-825]

Angimyofiblastomlar(AMFB), genital stromal tümörler içerisinde yer alan,nadir izlenen benign mezenkimal tümörlerdir. Genellikle orta-yaş bayanlarda görülüp, sıklıkla labium majörü daha az sıklıklada vajinayı etkileyebilmektedir. AMFB benzeri tümörler adı altında, nadiren erkekler de görülebilmektedir. Yerleşim yeri ve klinik prezentasyonu ile bartolin kistleri, alt genital tract lipomları veya nadiren de agresif anjiyomiksomalar ile karışabilmektedir. Vulvar kitle ile başvuran hastalarda, ön tanıda AMFB ler unutulmamalıdır. Tedavisi genellikle basit cerrahi eksizyondur.Bu olguda, bartolin kist yanlış ön tanısı ile medikal tedavi verilen AMFB olgusundan bahsedildi

Appendiks intussussepsiyonu nadir görülen ve semptomlarının apandisite olan benzerliği nedeniyle hem klinik hem de radyolojik olarak preoperatif tanısı oldukça güç olan bir durumdur. Burada akut batın bulguları ile başvuran tanı ve tedavi sonrasında appendiks intussussepsiyonu olarak değerlendirilen olguyu bildirdik. Diagnostik görüntüleme yöntemleri gelişmiş olsa da bazen preoperatif dönemde tanı koymada yardımcı olmamaktadırlar. Bu yüzden doktorlar akut batın ile başvuran hastalarda akut apandisit, tümör ve ek olarak intussussepsiyonu alternatif tanı olarak düşünmeleri önerilir.

Intussusception of the appendix is a rare condition. As the symptoms can mixed with acute apandicitis, the diagnosis is difficult both clinically and radiologically at the preoperative period. This article reports a case of appendiceal intussusception who was presented as acute abdomen. Although diagnostic imaging was improved, sometimes preoperative findings are not enough helpful for the diagnosis. Therefore doctors should consider alternative diagnosis such as appendicitis, tumor in addition to intussusception at acute abdomen . [Cukurova Med J 2012; 37(4.000): 238-242]

Objective: The aim of this study was to determine the potential, protective effects of amlodipine in an experimental, ischemia-reperfusion (I/R) model in the rabbit small intestine. Materials and Methods: The rabbits were divided into four groups: sham-operated, amlodipine (10 mg/kg) + sham-operated, I/R, and I/R + amlodipine (10 mg/kg) groups. An intestinal I/R model was applied to the rabbits. The superior mesenteric artery was occluded for 1 h with an atraumatic vascular clamp and then was reperfused for 2 h. Animals in the amlodipine and I/R + amlodipine groups received the amlodipine by oral gavage. At the end of the 2-h-reperfusion period, the animals were sacrificed. Results: Pretreatment with amlodipine significantly increased SOD activity and GSH levels to values close to those found in the serum from the I/R group. Rabbits in the I/R group showed high levels of serum MDA. Amlodipine pretreatment significantly reduced the serum MDA levels compared to the I/R group, although the MDA levels in the I/R + amlodipine group were still higher than in the sham-operated group. The I/R damage was ameliorated by amlodipine pretreatment, as evidenced by histopathological analysis. Conclusion: The present study is the first to report an attenuation of I/R-induced intestinal injury by the systemic administration of amlodipine.